-
2
-
-
1642578298
-
Dr. William Coley and tumour regression: A place in history or in the future
-
Hoption Cann, S. A.; van Netten, J. P.; van Netten, C. Dr. William Coley and tumour regression: a place in history or in the future. Postgrad. Med. J. 2003, 79, 672-680.
-
(2003)
Postgrad. Med. J.
, vol.79
, pp. 672-680
-
-
Hoption Cann, S.A.1
Van Netten, J.P.2
Van Netten, C.3
-
3
-
-
0000812865
-
Late results of the treatment of inoperable sarcoma by the mixed toxins of erysipelas and bacillus prodigiosus
-
Coley, W. B. Late results of the treatment of inoperable sarcoma by the mixed toxins of erysipelas and bacillus prodigiosus. Am. J. Med. Sci. 1906, 131, 375-430.
-
(1906)
Am. J. Med. Sci.
, vol.131
, pp. 375-430
-
-
Coley, W.B.1
-
4
-
-
0003396519
-
The beneficial effects of bacterial infections on host resistance to cancer: End results in 449 cases
-
2nd Edition. Monograph No 8. New York
-
Nauts, H. C. The beneficial effects of bacterial infections on host resistance to cancer: end results in 449 cases. 2nd Edition. Monograph No 8. New York: Cancer Res. Inst. 1980.
-
(1980)
Cancer Res. Inst.
-
-
Nauts, H.C.1
-
5
-
-
0014031945
-
Relations between bacterial lipopolysaccharide structures and those of human cells
-
Springer, G. F.; Wang, E. T.; Nichols, J. H.; Shear, J. M. Relations between bacterial lipopolysaccharide structures and those of human cells. Ann. NY Acad. Sci. 1966, 133(2), 566-579.
-
(1966)
Ann. NY Acad. Sci.
, vol.133
, Issue.2
, pp. 566-579
-
-
Springer, G.F.1
Wang, E.T.2
Nichols, J.H.3
Shear, J.M.4
-
6
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell, E. A.; Old, L. J.; Kassel, R. L.; Green, S.; Fiore, N.; Williamson, B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 1975, 72, 3666-3670.
-
(1975)
Proc. Natl. Acad. Sci. USA
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
7
-
-
0022393776
-
Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor
-
Marmenout, A.; Fransen, L.; Tavernier, J.; Van der Heyden, J.; Tizard, R.; Kawashima, E.; Shaw, A.; Fiers, W. Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor. Eur. J. Biochem. 1985, 152, 515-522.
-
(1985)
Eur. J. Biochem.
, vol.152
, pp. 515-522
-
-
Marmenout, A.1
Fransen, L.2
Tavernier, J.3
Van Der Heyden, J.4
Tizard, R.5
Kawashima, E.6
Shaw, A.7
Fiers, W.8
-
8
-
-
0021949137
-
Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor
-
Shirai, T.; Yamaguchi, H.; Ito, H.; Todd, C. W.; Wallace, R. B. Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. Nature 1985, 131, 803-806.
-
(1985)
Nature
, vol.131
, pp. 803-806
-
-
Shirai, T.1
Yamaguchi, H.2
Ito, H.3
Todd, C.W.4
Wallace, R.B.5
-
9
-
-
0021681058
-
Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin
-
Pennica, D.; Nedwin, G. E.; Hayflick, J. S.; Seeburg, P. H.; Derynck, R.; Palladino, M. A.; Kohr, W. J.; Aggarwal, B. B.; Goeddel, D. V. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature 1984, 312, 724-729.
-
(1984)
Nature
, vol.312
, pp. 724-729
-
-
Pennica, D.1
Nedwin, G.E.2
Hayflick, J.S.3
Seeburg, P.H.4
Derynck, R.5
Palladino, M.A.6
Kohr, W.J.7
Aggarwal, B.B.8
Goeddel, D.V.9
-
10
-
-
0025149247
-
A non-secretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact
-
Perez, C.; Albert, I.; DeFay, K.; Zachariades, N.; Gooding, L.; Kriegler, M. A non-secretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact. Cell 1990, 63(2), 251-258.
-
(1990)
Cell
, vol.63
, Issue.2
, pp. 251-258
-
-
Perez, C.1
Albert, I.2
Defay, K.3
Zachariades, N.4
Gooding, L.5
Kriegler, M.6
-
11
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor alpha from cells
-
Black, R. A.; Rauch, C. T.; Kozlosky, C. J.; Peschon, J. J.; Slack, J. L.; Wolfson, M. F.; Castner, B. J.; Stocking, K. L.; Reddy, P.; Srinivasan, S.; Nelson, N.; Boiani, N.; Schooley, K. A.; Gerhart, M.; Davis, R.; Fitzner, J. N.; Johnson, R. S.; Paxton, R. J.; March, C. J.; Cerretti, D. P. A metalloproteinase disintegrin that releases tumour-necrosis factor alpha from cells. Nature 1997, 385, 729-733.
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
Stocking, K.L.8
Reddy, P.9
Srinivasan, S.10
Nelson, N.11
Boiani, N.12
Schooley, K.A.13
Gerhart, M.14
Davis, R.15
Fitzner, J.N.16
Johnson, R.S.17
Paxton, R.J.18
March, C.J.19
Cerretti, D.P.20
more..
-
12
-
-
0026717674
-
The pathophysiology of tumor necrosis factors
-
Vassalli, P. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 1992, 10, 411-452.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 411-452
-
-
Vassalli, P.1
-
13
-
-
1542409974
-
Death receptors as targets of cancer therapeutics
-
Sheikh, M. S.; Huang, Y. Death receptors as targets of cancer therapeutics. Curr. Cancer Drug Targets 2004, 4(1), 97-104.
-
(2004)
Curr. Cancer Drug Targets
, vol.4
, Issue.1
, pp. 97-104
-
-
Sheikh, M.S.1
Huang, Y.2
-
14
-
-
0024357657
-
The structure of tumor necrosis factor-alpha at 2.6 a resolution. Implications for receptor binding
-
Eck, M. J.; Sprang, S. R. The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. J. Biol. Chem. 1989, 264(29), 17595-17605.
-
(1989)
J. Biol. Chem.
, vol.264
, Issue.29
, pp. 17595-17605
-
-
Eck, M.J.1
Sprang, S.R.2
-
15
-
-
0024539057
-
Structure of tumour necrosis factor
-
Jones, E. Y.; Stuart, D. I.; Walker, N. P. Structure of tumour necrosis factor. Nature 1989, 338(6212), 225-228.
-
(1989)
Nature
, vol.338
, Issue.6212
, pp. 225-228
-
-
Jones, E.Y.1
Stuart, D.I.2
Walker, N.P.3
-
16
-
-
0026563754
-
Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor
-
Brakebusch, C.; Nophar, Y.; Kemper, O.; Engelmann, H.; Wallach, D. Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. EMBO J. 1992, 11(3), 943-950.
-
(1992)
EMBO J.
, vol.11
, Issue.3
, pp. 943-950
-
-
Brakebusch, C.1
Nophar, Y.2
Kemper, O.3
Engelmann, H.4
Wallach, D.5
-
17
-
-
0025082527
-
Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity
-
Engelmann, H.; Holtmann, H.; Brakebusch, C.; Avni, Y. S.; Sarov, I.; Nophar, Y.; Hadas, E.; Leitner, O.; Wallach, D. Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. J. Biol. Chem. 1990, 265(24), 14497-14504.
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.24
, pp. 14497-14504
-
-
Engelmann, H.1
Holtmann, H.2
Brakebusch, C.3
Avni, Y.S.4
Sarov, I.5
Nophar, Y.6
Hadas, E.7
Leitner, O.8
Wallach, D.9
-
18
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
-
Grell, M.; Douni, E.; Wajant, H.; Lohden, M.; Clauss, M.; Maxeiner, B.; Georgopoulos, S.; Lesslauer, W.; Kollias, G.; Pfizenmaier, K.; Scheurich, P. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995, 83(5), 793-802.
-
(1995)
Cell
, vol.83
, Issue.5
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
Lohden, M.4
Clauss, M.5
Maxeiner, B.6
Georgopoulos, S.7
Lesslauer, W.8
Kollias, G.9
Pfizenmaier, K.10
Scheurich, P.11
-
19
-
-
0031882913
-
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
-
Grell, M.; Wajant, H.; Zimmermann, G.; Scheurich, P. The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc. Natl. Acad. Sci. USA 1998, 95(2), 570-575.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.2
, pp. 570-575
-
-
Grell, M.1
Wajant, H.2
Zimmermann, G.3
Scheurich, P.4
-
20
-
-
0029164968
-
Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor
-
Decoster, E.; Vanhaesebroeck, B.; Vandenabeele, P.; Grooten, J.; Fiers, W. Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor. J. Biol. Chem. 1995, 270(31), 18473-18478.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.31
, pp. 18473-18478
-
-
Decoster, E.1
Vanhaesebroeck, B.2
Vandenabeele, P.3
Grooten, J.4
Fiers, W.5
-
21
-
-
0024307648
-
A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity
-
Engelmann, H.; Aderka, D.; Rubinstein, M.; Rotman, D.; Wallach, D. A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. J. Biol. Chem. 1989, 264(20), 11974-11980.
-
(1989)
J. Biol. Chem.
, vol.264
, Issue.20
, pp. 11974-11980
-
-
Engelmann, H.1
Aderka, D.2
Rubinstein, M.3
Rotman, D.4
Wallach, D.5
-
22
-
-
0025165135
-
Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors
-
Engelmann, H.; Novick, D.; Wallach, D. Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J. Biol. Chem. 1990, 265(3), 1531-1536.
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.3
, pp. 1531-1536
-
-
Engelmann, H.1
Novick, D.2
Wallach, D.3
-
23
-
-
0034640286
-
Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme
-
Reddy, P.; Slack, J. L.; Davis, R.; Cerretti, D. P.; Kozlosky, C. J.; Blanton, R. A.; Shows, D.; Peschon, J. J.; Black, R. A. Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme. J. Biol. Chem. 2000, 275(19), 14608-14614.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.19
, pp. 14608-14614
-
-
Reddy, P.1
Slack, J.L.2
Davis, R.3
Cerretti, D.P.4
Kozlosky, C.J.5
Blanton, R.A.6
Shows, D.7
Peschon, J.J.8
Black, R.A.9
-
24
-
-
0026516744
-
Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors
-
Aderka, D.; Engelmann, H.; Maor, Y.; Brakebusch, C.; Wallach, D. Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J. Exp. Med. 1992, 175(2), 323-329.
-
(1992)
J. Exp. Med.
, vol.175
, Issue.2
, pp. 323-329
-
-
Aderka, D.1
Engelmann, H.2
Maor, Y.3
Brakebusch, C.4
Wallach, D.5
-
25
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach, D.; Varfolomeev, E. E.; Malinin, N. L.; Goltsev, Y. V.; Kovalenko, A. V.; Boldin, M. P. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 1999, 17, 331-367.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
26
-
-
0027275490
-
A novel domain within the 55 kd TNF receptor signals cell death
-
Tartaglia, L. A.; Ayres, T. M.; Wong, G. H.; Goeddel, D. V. A novel domain within the 55 kd TNF receptor signals cell death. Cell 1993, 74, 845-853.
-
(1993)
Cell
, vol.74
, pp. 845-853
-
-
Tartaglia, L.A.1
Ayres, T.M.2
Wong, G.H.3
Goeddel, D.V.4
-
27
-
-
0031567897
-
TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation
-
Lin, R. H.; Hwang, Y. W.; Yang, B. C.; Lin, C. S. TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation. J. Immunol. 1997, 158(2), 598-603.
-
(1997)
J. Immunol.
, vol.158
, Issue.2
, pp. 598-603
-
-
Lin, R.H.1
Hwang, Y.W.2
Yang, B.C.3
Lin, C.S.4
-
28
-
-
0031795272
-
Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells
-
Lucas, R.; Garcia, I.; Donati, Y. R.; Hribar, M.; Mandriota, S. J.; Giroud, C.; Buurman, W. A.; Fransen, L.; Suter, P. M.; Nunez, G.; Pepper, M. S.; Grau, G. E. Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells. Eur. J. Immunol. 1998, 28(11), 3577-3586.
-
(1998)
Eur. J. Immunol.
, vol.28
, Issue.11
, pp. 3577-3586
-
-
Lucas, R.1
Garcia, I.2
Donati, Y.R.3
Hribar, M.4
Mandriota, S.J.5
Giroud, C.6
Buurman, W.A.7
Fransen, L.8
Suter, P.M.9
Nunez, G.10
Pepper, M.S.11
Grau, G.E.12
-
29
-
-
0037149542
-
TNF-RII and C-IAP1 mediate ubiquitination and degradation of TRAF2
-
Li, X.; Yang, Y.; Ashwell, J. D. TNF-RII and C-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 2002, 416(6878), 345-347.
-
(2002)
Nature
, vol.416
, Issue.6878
, pp. 345-347
-
-
Li, X.1
Yang, Y.2
Ashwell, J.D.3
-
30
-
-
0026093190
-
Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro
-
Robaye, B.; Mosselmans, R.; Fiers, W.; Dumont, J. E.; Galand, P. Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro. Am. J. Pathol. 1991, 138(2), 447-453.
-
(1991)
Am. J. Pathol.
, vol.138
, Issue.2
, pp. 447-453
-
-
Robaye, B.1
Mosselmans, R.2
Fiers, W.3
Dumont, J.E.4
Galand, P.5
-
31
-
-
0040887215
-
Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma
-
Ruegg, C.; Yilmaz, A.; Bieler, G.; Bamat, J.; Chaubert, P.; Lejeune, F. J. Evidence for the involvement of endothelial cell integrin alphaVbeta3 in the disruption of the tumor vasculature induced by TNF and IFN-gamma. Nat. Med. 1998, 4(4), 408-414.
-
(1998)
Nat. Med.
, vol.4
, Issue.4
, pp. 408-414
-
-
Ruegg, C.1
Yilmaz, A.2
Bieler, G.3
Bamat, J.4
Chaubert, P.5
Lejeune, F.J.6
-
32
-
-
0027327619
-
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
-
Rothe, J.; Lesslauer, W.; Lotscher, H.; Lang, Y.; Koebel, P.; Kontgen, F.; Althage, A.; Zinkernagel, R.; Steinmetz, M.; Bluethmann, H. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 1993, 364, 798-802.
-
(1993)
Nature
, vol.364
, pp. 798-802
-
-
Rothe, J.1
Lesslauer, W.2
Lotscher, H.3
Lang, Y.4
Koebel, P.5
Kontgen, F.6
Althage, A.7
Zinkernagel, R.8
Steinmetz, M.9
Bluethmann, H.10
-
33
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K.; Matsuyama, T.; Kundig, T. M.; Wakeham, A.; Kishihara, K.; Shahinian, A.; Wiegmann, K.; Ohashi, P. S.; Kronke, M.; Mak, T. W. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993, 73, 457-467.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
34
-
-
0030240764
-
TNF receptors in murine Candida albicans infection: Evidence for an important role of TNF receptor p55 in antifungal defense
-
Steinshamn, S.; Bemelmans, M. H.; van Tits, L. J.; Bergh, K.; Buurman, W. A.; Waage, A. TNF receptors in murine Candida albicans infection: evidence for an important role of TNF receptor p55 in antifungal defense. J. Immunol. 1996, 157, 2155-2159.
-
(1996)
J. Immunol.
, vol.157
, pp. 2155-2159
-
-
Steinshamn, S.1
Bemelmans, M.H.2
Van Tits, L.J.3
Bergh, K.4
Buurman, W.A.5
Waage, A.6
-
35
-
-
0030722084
-
Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors
-
Ruby, J.; Bluethmann, H.; Peschon, J. J. Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors. J. Exp. Med. 1997, 186(9), 1591-1596.
-
(1997)
J. Exp. Med.
, vol.186
, Issue.9
, pp. 1591-1596
-
-
Ruby, J.1
Bluethmann, H.2
Peschon, J.J.3
-
36
-
-
0028218545
-
Mapping the lectin-like activity of tumor necrosis factor
-
Lucas, R.; Magez, S.; De Leys, R.; Fransen, L.; Scheerlinck, J. P.; Rampelberg, M.; Sablon, E.; De Baetselier, P. Mapping the lectin-like activity of tumor necrosis factor. Science 1994, 263(5148), 814-817.
-
(1994)
Science
, vol.263
, Issue.5148
, pp. 814-817
-
-
Lucas, R.1
Magez, S.2
De Leys, R.3
Fransen, L.4
Scheerlinck, J.P.5
Rampelberg, M.6
Sablon, E.7
De Baetselier, P.8
-
37
-
-
0032986496
-
Tumor necrosis factor alpha is a key mediator in the regulation of experimental Trypanosoma brucei infections
-
Magez, S.; Radwanska, M.; Beschin, A.; Sekikawa, K.; De Baetselier, P. Tumor necrosis factor alpha is a key mediator in the regulation of experimental Trypanosoma brucei infections. Infect. Immun. 1999, 67(6), 3128-3132.
-
(1999)
Infect. Immun.
, vol.67
, Issue.6
, pp. 3128-3132
-
-
Magez, S.1
Radwanska, M.2
Beschin, A.3
Sekikawa, K.4
De Baetselier, P.5
-
38
-
-
0023671596
-
The role of cachectin/TNF in endotoxic shock and cachexia
-
Cerami, A.; Beutler, B. The role of cachectin/TNF in endotoxic shock and cachexia. Immunol. Today 1988, 9(1), 28-31.
-
(1988)
Immunol. Today
, vol.9
, Issue.1
, pp. 28-31
-
-
Cerami, A.1
Beutler, B.2
-
39
-
-
0023177157
-
Tumor necrosis factor mediates endotoxic effects in mice
-
Bauss, F.; Droge, W.; Mannel, D. N. Tumor necrosis factor mediates endotoxic effects in mice. Infect. Immun. 1987, 55(7), 1622-1625.
-
(1987)
Infect. Immun.
, vol.55
, Issue.7
, pp. 1622-1625
-
-
Bauss, F.1
Droge, W.2
Mannel, D.N.3
-
40
-
-
0023189866
-
Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria
-
Grau, G. E.; Fajardo, L. F.; Piguet, P. F.; Allet, B.; Lambert, P. H.; Vassalli, P. Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 1987, 237(4819), 1210-1212.
-
(1987)
Science
, vol.237
, Issue.4819
, pp. 1210-1212
-
-
Grau, G.E.1
Fajardo, L.F.2
Piguet, P.F.3
Allet, B.4
Lambert, P.H.5
Vassalli, P.6
-
41
-
-
0343505811
-
In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis
-
Kusters, S.; Tiegs, G.; Alexopoulou, L.; Pasparakis, M.; Douni, E.; Kunstle, G.; Bluethmann, H.; Wendel, A.; Pfizenmaier, K.; Kollias, G.; Grell, M. In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. Eur. J. Immunol. 1997, 27(11), 2870-2875.
-
(1997)
Eur. J. Immunol.
, vol.27
, Issue.11
, pp. 2870-2875
-
-
Kusters, S.1
Tiegs, G.2
Alexopoulou, L.3
Pasparakis, M.4
Douni, E.5
Kunstle, G.6
Bluethmann, H.7
Wendel, A.8
Pfizenmaier, K.9
Kollias, G.10
Grell, M.11
-
42
-
-
15644382222
-
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria
-
Lucas, R.; Juillard, P.; Decoster, E.; Redard, M.; Burger, D.; Donati, Y.; Giroud, C.; Monso-Hinard, C.; De Kesel, T.; Buurman, W. A.; Moore, M. W.; Dayer, J. M.; Fiers, W.; Bluethmann, H.; Grau, G. E. Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria. Eur. J. Immunol. 1997, 27(7), 1719-1725.
-
(1997)
Eur. J. Immunol.
, vol.27
, Issue.7
, pp. 1719-1725
-
-
Lucas, R.1
Juillard, P.2
Decoster, E.3
Redard, M.4
Burger, D.5
Donati, Y.6
Giroud, C.7
Monso-Hinard, C.8
De Kesel, T.9
Buurman, W.A.10
Moore, M.W.11
Dayer, J.M.12
Fiers, W.13
Bluethmann, H.14
Grau, G.E.15
-
43
-
-
0034761722
-
Pathogenesis of cerebral malaria: Recent experimental data and possible applications for humans
-
Lou, J.; Lucas, R.; Grau, G. E. Pathogenesis of cerebral malaria: recent experimental data and possible applications for humans. Clin. Microbiol. Rev. 2001, 14(4), 810-820.
-
(2001)
Clin. Microbiol. Rev.
, vol.14
, Issue.4
, pp. 810-820
-
-
Lou, J.1
Lucas, R.2
Grau, G.E.3
-
44
-
-
0038783439
-
GM-CSF restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro
-
Xu, J.; Lucas, R.; Schuchmann, M.; Kuhnle, S.; Meergans, T.; Barreiros, A. P.; Lohse, A. W.; Otto, G.; Wendel, A. GM-CSF restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro. J. Immunol. 2003, 171(2), 938-947.
-
(2003)
J. Immunol.
, vol.171
, Issue.2
, pp. 938-947
-
-
Xu, J.1
Lucas, R.2
Schuchmann, M.3
Kuhnle, S.4
Meergans, T.5
Barreiros, A.P.6
Lohse, A.W.7
Otto, G.8
Wendel, A.9
-
45
-
-
2142659293
-
The potential of GM-CSF to improve resistance against infections in organ transplantation
-
Xu, J.; Lucas, R.; Wendel, A. The potential of GM-CSF to improve resistance against infections in organ transplantation. Trends Pharmacol. Sci. 2004, 25(5), 254-258.
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, Issue.5
, pp. 254-258
-
-
Xu, J.1
Lucas, R.2
Wendel, A.3
-
46
-
-
0035846326
-
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
-
Keane, J.; Gershon, S.; Wise, R. P.; Mirabile-Levens, E.; Kasznica, J.; Schwieterman, W. D.; Siegel, J. N.; Braun, M. M. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N. Engl. J. Med. 2001, 345(15), 1098-1104.
-
(2001)
N. Engl. J. Med.
, vol.345
, Issue.15
, pp. 1098-1104
-
-
Keane, J.1
Gershon, S.2
Wise, R.P.3
Mirabile-Levens, E.4
Kasznica, J.5
Schwieterman, W.D.6
Siegel, J.N.7
Braun, M.M.8
-
47
-
-
0036852241
-
Cancer immunoediting: From immunosurveillance to tumor escape
-
Dunn, G. P.; Bruce, A. T.; Ikeda, H.; Old, L. J.; Schreiber, R. D. Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol. 2002 3(11), 991-998.
-
(2002)
Nat. Immunol.
, vol.3
, Issue.11
, pp. 991-998
-
-
Dunn, G.P.1
Bruce, A.T.2
Ikeda, H.3
Old, L.J.4
Schreiber, R.D.5
-
48
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L. M.; Werb, Z. Inflammation and cancer. Nature 2002, 420(6917), 860-867.
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
49
-
-
0037057521
-
Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
-
Harmey, J. H.; Bucana, C. D.; Lu, W.; Byrne, A. M.; McDonnell, S.; Lynch, C.; Bouchier-Hayes, D.; Dong, Z. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int. J. Cancer 2002, 101(5), 415-422.
-
(2002)
Int. J. Cancer
, vol.101
, Issue.5
, pp. 415-422
-
-
Harmey, J.H.1
Bucana, C.D.2
Lu, W.3
Byrne, A.M.4
McDonnell, S.5
Lynch, C.6
Bouchier-Hayes, D.7
Dong, Z.8
-
50
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin, M.; Cao, Y.; Greten, F. R.; Li, Z. W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer 2002, 2(4), 301-310.
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.4
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
51
-
-
4544224979
-
Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression
-
Luo, J. L.; Maeda, S.; Hsu, L. C.; Yagita, H.; Karin, M. Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. Cancer Cell. 2004, 6(3), 297-305.
-
(2004)
Cancer Cell.
, vol.6
, Issue.3
, pp. 297-305
-
-
Luo, J.L.1
Maeda, S.2
Hsu, L.C.3
Yagita, H.4
Karin, M.5
-
52
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
-
Wang, C. Y.; Cusack, J. C. Jr.; Liu, R.; Baldwin, A. S. Jr. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat. Med. 1999, 5(4), 412-417.
-
(1999)
Nat. Med.
, vol.5
, Issue.4
, pp. 412-417
-
-
Wang, C.Y.1
Cusack Jr., J.C.2
Liu, R.3
Baldwin Jr., A.S.4
-
53
-
-
0023778218
-
Recombinant human tumor necrosis factor administered as a 24-hour intravenous infusion. A phase I and pharmacologic study
-
Spriggs, D. R.; Sherman, M. L.; Michie, H.; Arthur, K. A.; Imamura, K.; Wilmore, D.; Frei, E. 3rd.; Kufe, D. W. Recombinant human tumor necrosis factor administered as a 24-hour intravenous infusion. A phase I and pharmacologic study. J. Natl. Cancer Inst. 1988, 80(13), 1039-1044.
-
(1988)
J. Natl. Cancer Inst.
, vol.80
, Issue.13
, pp. 1039-1044
-
-
Spriggs, D.R.1
Sherman, M.L.2
Michie, H.3
Arthur, K.A.4
Imamura, K.5
Wilmore, D.6
Frei III, E.7
Kufe, D.W.8
-
54
-
-
0023863335
-
Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: Phase I toxicity and effects on lipid metabolism
-
Sherman, M. L.; Spriggs, D. R.; Arthur, K. A.; Imamura, K.; Frei, E. 3rd.; Kufe, D. W. Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism. J. Clin. Oncol. 1988, 6(2), 344-350.
-
(1988)
J. Clin. Oncol.
, vol.6
, Issue.2
, pp. 344-350
-
-
Sherman, M.L.1
Spriggs, D.R.2
Arthur, K.A.3
Imamura, K.4
Frei III, E.5
Kufe, D.W.6
-
55
-
-
0025311435
-
Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice
-
Giavazzi, R.; Garofalo, A.; Bani, M. R.; Abbate, M.; Ghezzi, P.; Boraschi, D.; Mantovani, A.; Dejana, E. Interleukin 1-induced augmentation of experimental metastases from a human melanoma in nude mice. Cancer Res. 1990, 50(15), 4771-4775.
-
(1990)
Cancer Res.
, vol.50
, Issue.15
, pp. 4771-4775
-
-
Giavazzi, R.1
Garofalo, A.2
Bani, M.R.3
Abbate, M.4
Ghezzi, P.5
Boraschi, D.6
Mantovani, A.7
Dejana, E.8
-
56
-
-
0027534917
-
Enhancement of experimental metastasis by tumor necrosis factor
-
Orosz, P.; Echtenacher, B.; Falk, W.; Ruschoff, J.; Weber, D.; Mannel, D. N. Enhancement of experimental metastasis by tumor necrosis factor. J. Exp. Med. 1993, 177(5), 1391-1398.
-
(1993)
J. Exp. Med.
, vol.177
, Issue.5
, pp. 1391-1398
-
-
Orosz, P.1
Echtenacher, B.2
Falk, W.3
Ruschoff, J.4
Weber, D.5
Mannel, D.N.6
-
57
-
-
0029887296
-
TNF promotes metastasis by impairing natural killer cell activity
-
Hafner, M.; Orosz, P.; Kruger, A.; Mannel, D. N. TNF promotes metastasis by impairing natural killer cell activity. Int. J. Cancer 1996, 66(3), 388-392.
-
(1996)
Int. J. Cancer
, vol.66
, Issue.3
, pp. 388-392
-
-
Hafner, M.1
Orosz, P.2
Kruger, A.3
Mannel, D.N.4
-
58
-
-
8344234108
-
Cachexia in cancer-zeroing in on myosin
-
Chamberlain, J. S. Cachexia in cancer-zeroing in on myosin. N. Engl. J. Med. 2004, 351(20), 2124-2125.
-
(2004)
N. Engl. J. Med.
, vol.351
, Issue.20
, pp. 2124-2125
-
-
Chamberlain, J.S.1
-
59
-
-
4344697232
-
Cancer cachexia
-
Tisdale, M. J. Cancer cachexia. Langenbecks Arch. Surg. 2004, 389(4), 299-305.
-
(2004)
Langenbecks Arch. Surg.
, vol.389
, Issue.4
, pp. 299-305
-
-
Tisdale, M.J.1
-
60
-
-
4043154377
-
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
-
Acharyya, S.; Ladner, K. J.; Nelsen, L. L.; Damrauer, J.; Reiser P. J.; Swoap, S.; Guttridge, D. C. Cancer cachexia is regulated by selective targeting of skeletal muscle gene products. J. Clin. Invest. 2004, 114(3), 370-378.
-
(2004)
J. Clin. Invest.
, vol.114
, Issue.3
, pp. 370-378
-
-
Acharyya, S.1
Ladner, K.J.2
Nelsen, L.L.3
Damrauer, J.4
Reiser, P.J.5
Swoap, S.6
Guttridge, D.C.7
-
61
-
-
8544237014
-
Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia
-
Kwak, K. S.; Zhou, X.; Solomon, V.; Baracos, V. E.; Davis, J.; Bannon, A. W.; Boyle, W. J.; Lacey, D. L.; Han, H. Q. Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia. Cancer Res. 2004, 64(22), 8193-8198.
-
(2004)
Cancer Res.
, vol.64
, Issue.22
, pp. 8193-8198
-
-
Kwak, K.S.1
Zhou, X.2
Solomon, V.3
Baracos, V.E.4
Davis, J.5
Bannon, A.W.6
Boyle, W.J.7
Lacey, D.L.8
Han, H.Q.9
-
62
-
-
0033711655
-
Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase
-
Cauwels, A.; Van Molle, W.; Janssen, B.; Everaerdt, B.; Huang, P.; Fiers, W.; Brouckaert, P. Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase. Immunity 2000, 13(2), 223-231.
-
(2000)
Immunity
, vol.13
, Issue.2
, pp. 223-231
-
-
Cauwels, A.1
Van Molle, W.2
Janssen, B.3
Everaerdt, B.4
Huang, P.5
Fiers, W.6
Brouckaert, P.7
-
63
-
-
0027998359
-
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest
-
Leist, M.; Gantner, F.; Bohlinger, I.; Germann, P. G.; Tiegs, G.; Wendel, A. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J. Immunol. 1994, 153(4), 1778-1788.
-
(1994)
J. Immunol.
, vol.153
, Issue.4
, pp. 1778-1788
-
-
Leist, M.1
Gantner, F.2
Bohlinger, I.3
Germann, P.G.4
Tiegs, G.5
Wendel, A.6
-
64
-
-
0028895940
-
Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release
-
Leist, M.; Gantner, F.; Jilg, S.; Wendel, A. Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release. J. Immunol. 1995, 154(3), 1307-1316.
-
(1995)
J. Immunol.
, vol.154
, Issue.3
, pp. 1307-1316
-
-
Leist, M.1
Gantner, F.2
Jilg, S.3
Wendel, A.4
-
65
-
-
0025756330
-
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific
-
Lewis, M.; Tartaglia, L. A.; Lee, A.; Bennett, G. L.; Rice, G. C.; Wong, G. H.; Chen, E. Y.; Goeddel, D. V. Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. Proc. Natl. Acad. Sci. USA 1991, 88(7), 2830-2834.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, Issue.7
, pp. 2830-2834
-
-
Lewis, M.1
Tartaglia, L.A.2
Lee, A.3
Bennett, G.L.4
Rice, G.C.5
Wong, G.H.6
Chen, E.Y.7
Goeddel, D.V.8
-
66
-
-
0027392199
-
Human TNF mutants with selective activity on the p55 receptor
-
Van Ostade, X.; Vandenabeele, P.; Everaerdt, B.; Loetscher, H.; Gentz, R.; Brockhaus, M.; Lesslauer, W.; Tavernier, J.; Brouckaert, P.; Fiers, W. Human TNF mutants with selective activity on the p55 receptor. Nature 1993, 361(6409), 266-269.
-
(1993)
Nature
, vol.361
, Issue.6409
, pp. 266-269
-
-
Van Ostade, X.1
Vandenabeele, P.2
Everaerdt, B.3
Loetscher, H.4
Gentz, R.5
Brockhaus, M.6
Lesslauer, W.7
Tavernier, J.8
Brouckaert, P.9
Fiers, W.10
-
67
-
-
0028203560
-
A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon
-
Van Zee, K. J.; Stackpole, S. A.; Montegut, W. J.; Rogy, M. A.; Galvano, S. E.; Hsu, K. C.; Chao, M.; Meschter, C. L.; Loetscher, H.; Stuber, D. et al. A human tumor necrosis factor (TNF) alpha mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon. J. Exp. Med. 1994, 179(4), 1185-1191.
-
(1994)
J. Exp. Med.
, vol.179
, Issue.4
, pp. 1185-1191
-
-
Van Zee, K.J.1
Stackpole, S.A.2
Montegut, W.J.3
Rogy, M.A.4
Galvano, S.E.5
Hsu, K.C.6
Chao, M.7
Meschter, C.L.8
Loetscher, H.9
Stuber, D.10
-
68
-
-
0036772312
-
Bioavailability of recombinant tumor necrosis factor determines its lethality in mice
-
Ameloot, P.; Takahashi, N.; Everaerdt, B.; Hostens, J.; Eugster, H. P.; Fiers, W.; Brouckaert, P. Bioavailability of recombinant tumor necrosis factor determines its lethality in mice. Eur. J. Immunol. 2002, 32(10), 2759-2765.
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.10
, pp. 2759-2765
-
-
Ameloot, P.1
Takahashi, N.2
Everaerdt, B.3
Hostens, J.4
Eugster, H.P.5
Fiers, W.6
Brouckaert, P.7
-
69
-
-
0030587125
-
Differential activation of the nuclear factor-kappa B by TNF mutants specific for the p60 and p80 TNF receptors
-
Chainy, G. B.; Singh, S.; Raju, U.; Aggarwal, B. B. Differential activation of the nuclear factor-kappa B by TNF mutants specific for the p60 and p80 TNF receptors. J. Immunol. 1996, 157(6), 2410-2417.
-
(1996)
J. Immunol.
, vol.157
, Issue.6
, pp. 2410-2417
-
-
Chainy, G.B.1
Singh, S.2
Raju, U.3
Aggarwal, B.B.4
-
70
-
-
0029115675
-
Novel mutant of tumor necrosis factor alpha (F4614) with reduced hypotensive effect
-
Shikama, H.; Miyata, K.; Sakae, N.; Mitsuishi, Y.; Nishimura, K.; Kuroda, K.; Kato, M. Novel mutant of tumor necrosis factor alpha (F4614) with reduced hypotensive effect. J. Interferon Cytokine Res. 1995, 15(8), 677-684.
-
(1995)
J. Interferon Cytokine Res.
, vol.15
, Issue.8
, pp. 677-684
-
-
Shikama, H.1
Miyata, K.2
Sakae, N.3
Mitsuishi, Y.4
Nishimura, K.5
Kuroda, K.6
Kato, M.7
-
71
-
-
17144440090
-
A novel human tumor necrosis factor alfa mutant, F4614, inhibits in vitro and in vivo growth of murine and human hepatoma: Implication for immunotherapy of human hepatocellular carcinoma
-
Atarashi, Y.; Yasumura, S.; Nambu, S.; Yoshio, Y.; Murakami, J.; Takahara, T.; Higuchi, K.; Watanabe, A.; Miyata, K.; Kato, M. A novel human tumor necrosis factor alfa mutant, F4614, inhibits in vitro and in vivo growth of murine and human hepatoma: implication for immunotherapy of human hepatocellular carcinoma. Hepatology 1998, 28(1), 57-67.
-
(1998)
Hepatology
, vol.28
, Issue.1
, pp. 57-67
-
-
Atarashi, Y.1
Yasumura, S.2
Nambu, S.3
Yoshio, Y.4
Murakami, J.5
Takahara, T.6
Higuchi, K.7
Watanabe, A.8
Miyata, K.9
Kato, M.10
-
72
-
-
0031914977
-
High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity
-
Cha, S. S.; Kim, J. S.; Cho, H. S.; Shin, N. K.; Jeong, W.; Shin, H. C.; Kim, Y. J.; Hahn, J. H.; Oh, B. H. High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity. J. Biol. Chem. 1998, 273(4), 2153-2160.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.4
, pp. 2153-2160
-
-
Cha, S.S.1
Kim, J.S.2
Cho, H.S.3
Shin, N.K.4
Jeong, W.5
Shin, H.C.6
Kim, Y.J.7
Hahn, J.H.8
Oh, B.H.9
-
73
-
-
0023259013
-
Uromodulin (Tamm-Horsfall glycoprotein): A renal ligand for lymphokines
-
Hession, C.; Decker, J. M.; Sherblom, A. P.; Kumar, S.; Yue, C. C.; Mattaliano, R. J.; Tizard, R.; Kawashima, E.; Schmeissner, U.; Heletky, S.; Muchmore, A. V. Uromodulin (Tamm-Horsfall glycoprotein): a renal ligand for lymphokines. Science 1987, 237(4821), 1479-1484.
-
(1987)
Science
, vol.237
, Issue.4821
, pp. 1479-1484
-
-
Hession, C.1
Decker, J.M.2
Sherblom, A.P.3
Kumar, S.4
Yue, C.C.5
Mattaliano, R.J.6
Tizard, R.7
Kawashima, E.8
Schmeissner, U.9
Heletky, S.10
Muchmore, A.V.11
-
74
-
-
0023895601
-
The lectin-like interaction between recombinant tumor necrosis factor and uromodulin
-
Sherblom, A. P.; Decker, J. M.; Muchmore, A. V. The lectin-like interaction between recombinant tumor necrosis factor and uromodulin. J. Biol. Chem. 1988, 263(11), 5418-5424.
-
(1988)
J. Biol. Chem.
, vol.263
, Issue.11
, pp. 5418-5424
-
-
Sherblom, A.P.1
Decker, J.M.2
Muchmore, A.V.3
-
75
-
-
0030919489
-
Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei
-
Magez, S.; Geuskens, M.; Beschin, A.; del Favero, H.; Verschueren, H.; Lucas, R.; Pays, E.; de Baetselier P. Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei. J. Cell Biol. 1997, 137(3), 715-727.
-
(1997)
J. Cell Biol.
, vol.137
, Issue.3
, pp. 715-727
-
-
Magez, S.1
Geuskens, M.2
Beschin, A.3
Del Favero, H.4
Verschueren, H.5
Lucas, R.6
Pays, E.7
De Baetselier, P.8
-
76
-
-
0030962992
-
Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity
-
Lucas, R.; Echtenacher, B.; Sablon, E.; Juillard, P.; Magez, S.; Lou, J.; Donati, Y.; Bosman, F.; Van de Voorde, A.; Fransen L.; Mannel, D. N.; Grau, G. E.; de Baetselier, P. Generation of a mouse tumor necrosis factor mutant with antiperitonitis and desensitization activities comparable to those of the wild type but with reduced systemic toxicity. Infect. Immun. 1997, 65(6), 2006-2010.
-
(1997)
Infect. Immun.
, vol.65
, Issue.6
, pp. 2006-2010
-
-
Lucas, R.1
Echtenacher, B.2
Sablon, E.3
Juillard, P.4
Magez, S.5
Lou, J.6
Donati, Y.7
Bosman, F.8
Van De Voorde, A.9
Fransen, L.10
Mannel, D.N.11
Grau, G.E.12
De Baetselier, P.13
-
77
-
-
0034992333
-
Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium
-
Fukuda, N.; Jayr, C.; Lazrak, A.; Wang, Y.; Lucas, R.; Matalon, S.; Matthay, M. A. Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium. Am. J. Physiol. Lung Cell Mol. Physiol. 2001, 280(6), L1258-L1265.
-
(2001)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.280
, Issue.6
-
-
Fukuda, N.1
Jayr, C.2
Lazrak, A.3
Wang, Y.4
Lucas, R.5
Matalon, S.6
Matthay, M.A.7
-
78
-
-
0032825294
-
The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages
-
Hribar, M.; Bloc, A.; van der Goot, F. G.; Fransen, L.; De Baetselier, P.; Grau, G. E.; Bluethmann, H.; Matthay, M. A.; Dunant, Y.; Pugin, J.; Lucas, R. The lectin-like domain of tumor necrosis factor-alpha increases membrane conductance in microvascular endothelial cells and peritoneal macrophages. Eur. J. Immunol. 1999, 29(10), 3105-3111.
-
(1999)
Eur. J. Immunol.
, vol.29
, Issue.10
, pp. 3105-3111
-
-
Hribar, M.1
Bloc, A.2
Van Der Goot, F.G.3
Fransen, L.4
De Baetselier, P.5
Grau, G.E.6
Bluethmann, H.7
Matthay, M.A.8
Dunant, Y.9
Pugin, J.10
Lucas, R.11
-
79
-
-
0035866033
-
Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule
-
Lucas, R.; Montesano, R.; Pepper, M. S.; Hafner, M.; Sablon, E.; Dunant, Y.; Grau, G. E.; De Baetselier, P.; Mannel, D.; Fransen, L. Lectin-deficient TNF mutants display comparable anti-tumour but reduced pro-metastatic potential as compared to the wild-type molecule. Int. J. Cancer 2001, 91(4), 543-549.
-
(2001)
Int. J. Cancer
, vol.91
, Issue.4
, pp. 543-549
-
-
Lucas, R.1
Montesano, R.2
Pepper, M.S.3
Hafner, M.4
Sablon, E.5
Dunant, Y.6
Grau, G.E.7
De Baetselier, P.8
Mannel, D.9
Fransen, L.10
-
80
-
-
0031059247
-
Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins
-
Leist, M.; Gantner, F.; Naumann, H.; Bluethmann, H.; Vogt, K.; Brigelius-Flohe, R.; Nicotera, P.; Volk, H. D.; Wendel, A. Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. Gastroenterology 1997, 112(3), 923-934.
-
(1997)
Gastroenterology
, vol.112
, Issue.3
, pp. 923-934
-
-
Leist, M.1
Gantner, F.2
Naumann, H.3
Bluethmann, H.4
Vogt, K.5
Brigelius-Flohe, R.6
Nicotera, P.7
Volk, H.D.8
Wendel, A.9
-
81
-
-
0031617224
-
Cytokine-mediated hepatic apoptosis
-
Leist, M.; Gantner, F.; Kunstle, G.; Wendel, A. Cytokine-mediated hepatic apoptosis. Rev. Physiol. Biochem. Pharmacol. 1998, 133, 109-155.
-
(1998)
Rev. Physiol. Biochem. Pharmacol.
, vol.133
, pp. 109-155
-
-
Leist, M.1
Gantner, F.2
Kunstle, G.3
Wendel, A.4
-
82
-
-
0030982279
-
Liver apoptosis
-
Feldmann, G. Liver apoptosis. J. Hepatol. 1997, 26(Suppl. 2), 1-11.
-
(1997)
J. Hepatol.
, vol.26
, Issue.SUPPL. 2
, pp. 1-11
-
-
Feldmann, G.1
-
83
-
-
0034007745
-
Liver regeneration
-
Fausto, N. Liver regeneration. J. Hepatol. 2000, 32(Suppl. 1), 19-31.
-
(2000)
J. Hepatol.
, vol.32
, Issue.SUPPL. 1
, pp. 19-31
-
-
Fausto, N.1
-
84
-
-
0036142543
-
Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver
-
Rudiger, H. A.; Clavien, P. A. Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology 2002, 122(1), 202-210.
-
(2002)
Gastroenterology
, vol.122
, Issue.1
, pp. 202-210
-
-
Rudiger, H.A.1
Clavien, P.A.2
-
85
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi, A.; Pai, R. C.; Fong, S.; Leung, S.; Lawrence, D. A.; Marsters, S. A.; Blackie, C.; Chang, L.; McMurtrey, A. E.; Hebert, A.; DeForge, L.; Koumenis, I. L.; Lewis, D.; Harris, L.; Bussiere, J.; Koeppen, H.; Shahrokh, Z.; Schwall, R. H. Safety and antitumor activity of recombinant soluble Apo2 ligand. J. Clin. Invest. 1999, 104(2), 155-162.
-
(1999)
J. Clin. Invest.
, vol.104
, Issue.2
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
Deforge, L.11
Koumenis, I.L.12
Lewis, D.13
Harris, L.14
Bussiere, J.15
Koeppen, H.16
Shahrokh, Z.17
Schwall, R.H.18
-
86
-
-
9244237679
-
TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
-
Hao, C.; Song, J. H.; Hsi, B.; Lewis, J.; Song, D. K.; Petruk, K. C.; Tyrrell, D. L.; Kneteman, N. M. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 2004, 64(23), 8502-8506.
-
(2004)
Cancer Res.
, vol.64
, Issue.23
, pp. 8502-8506
-
-
Hao, C.1
Song, J.H.2
Hsi, B.3
Lewis, J.4
Song, D.K.5
Petruk, K.C.6
Tyrrell, D.L.7
Kneteman, N.M.8
-
87
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan, J. P.; Marsters, S. A.; Pitti, R. M.; Gurney, A.; Skubatch, M.; Baldwin, D.; Ramakrishnan, L.; Gray, C. L.; Baker, K.; Wood, W. I.; Goddard, A. D.; Godowski, P.; Ashkenazi A. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997, 277(5327), 818-821.
-
(1997)
Science
, vol.277
, Issue.5327
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
Ramakrishnan, L.7
Gray, C.L.8
Baker, K.9
Wood, W.I.10
Goddard, A.D.11
Godowski, P.12
Ashkenazi, A.13
-
88
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan, G.; Ni, J.; Wei, Y. F.; Yu, G.; Gentz, R.; Dixit, V. M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997, 277(5327), 815-818.
-
(1997)
Science
, vol.277
, Issue.5327
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
89
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo, M.; Kim, T. H.; Seol, D. W.; Esplen, J. E.; Dorko, K.; Billiar, T. R.; Strom, S. C. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 2000, 6(5), 564-567.
-
(2000)
Nat. Med.
, vol.6
, Issue.5
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
Esplen, J.E.4
Dorko, K.5
Billiar, T.R.6
Strom, S.C.7
-
90
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence, D.; Shahrokh, Z.; Marsters, S.; Achilles, K.; Shih, D.; Mounho, B.; Hillan, K.; Totpal, K.; DeForge, L.; Schow, P.; Hooley, J.; Sherwood, S.; Pai, R.; Leung, S.; Khan, L.; Gliniak, B.; Bussiere, J.; Smith, C. A.; Strom, S. S.; Kelley, S.; Fox, J. A.; Thomas, D.; Ashkenazi, A. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat. Med. 2001, 7(4), 383-385.
-
(2001)
Nat. Med.
, vol.7
, Issue.4
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan, K.7
Totpal, K.8
DeForge, L.9
Schow, P.10
Hooley, J.11
Sherwood, S.12
Pai, R.13
Leung, S.14
Khan, L.15
Gliniak, B.16
Bussiere, J.17
Smith, C.A.18
Strom, S.S.19
Kelley, S.20
Fox, J.A.21
Thomas, D.22
Ashkenazi, A.23
more..
-
91
-
-
1542466794
-
Critical roles of TRAIL in hepatic cell death and hepatic inflammation
-
Zheng, S. J.; Wang, P.; Tsabary, G.; Chen, Y. H. Critical roles of TRAIL in hepatic cell death and hepatic inflammation. J. Clin. Invest. 2004, 113(1), 58-64.
-
(2004)
J. Clin. Invest.
, vol.113
, Issue.1
, pp. 58-64
-
-
Zheng, S.J.1
Wang, P.2
Tsabary, G.3
Chen, Y.H.4
-
92
-
-
10344260656
-
TRAIL-R as a negative regulator of innate immune cell responses
-
Diehl, G. E.; Yue, H. H.; Hsieh, K.; Kuang, A. A.; Ho, M.; Morici, L. A.; Lenz, L. L.; Cado, D.; Riley, L. W.; Winoto, A. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 2004, 21(6), 877-889.
-
(2004)
Immunity
, vol.21
, Issue.6
, pp. 877-889
-
-
Diehl, G.E.1
Yue, H.H.2
Hsieh, K.3
Kuang, A.A.4
Ho, M.5
Morici, L.A.6
Lenz, L.L.7
Cado, D.8
Riley, L.W.9
Winoto, A.10
-
93
-
-
4444229437
-
Abnormal TNF activity in Timp3-/- Mice leads to chronic hepatic inflammation and failure of liver regeneration
-
Mohammed, F. F.; Smookler, D. S.; Taylor, S. E.; Fingleton, B.; Kassiri, Z.; Sanchez, O. H.; English, J. L.; Matrisian, L. M.; Au, B.; Yeh, W. C.; Khokha, R. Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat. Genet. 2004, 36(9), 969-977.
-
(2004)
Nat. Genet.
, vol.36
, Issue.9
, pp. 969-977
-
-
Mohammed, F.F.1
Smookler, D.S.2
Taylor, S.E.3
Fingleton, B.4
Kassiri, Z.5
Sanchez, O.H.6
English, J.L.7
Matrisian, L.M.8
Au, B.9
Yeh, W.C.10
Khokha, R.11
-
94
-
-
0028783367
-
Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage
-
Galle, P. R.; Hofmann, W. J.; Walczak, H.; Schauer, H.; Otto, G.; Stremmel, W, Krammer, P. H.; Runkel, L. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J. Exp. Med. 1995, 182(5), 1223-1230.
-
(1995)
J. Exp. Med.
, vol.182
, Issue.5
, pp. 1223-1230
-
-
Galle, P.R.1
Hofmann, W.J.2
Walczak, H.3
Schauer, H.4
Otto, G.5
Stremmel, W.6
Krammer, P.H.7
Runkel, L.8
-
95
-
-
0030858904
-
Apoptosis in liver disease
-
Galle, P. R. Apoptosis in liver disease. J. Hepatol. 1997, 27(2), 405-412.
-
(1997)
J. Hepatol.
, vol.27
, Issue.2
, pp. 405-412
-
-
Galle, P.R.1
-
96
-
-
0031682110
-
Mechanisms of hepatic toxicity. I. TNF-induced liver injury
-
Bradham, C. A.; Plumpe, J.; Manns, M. P.; Brenner, D. A.; Trautwein, C. Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am. J. Physiol. 1998, 275(3 Pt 1), G387-G392.
-
(1998)
Am. J. Physiol.
, vol.275
, Issue.3 PART 1
-
-
Bradham, C.A.1
Plumpe, J.2
Manns, M.P.3
Brenner, D.A.4
Trautwein, C.5
-
97
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
Leist, M.; Single, B.; Castoldi, A. F.; Kuhnle, S.; Nicotera, P. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 1997, 185(8), 1481-1486.
-
(1997)
J. Exp. Med.
, vol.185
, Issue.8
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
98
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi, Y.; Shimizu, S.; Tsujimoto, Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 1997, 57(10), 1835-1840.
-
(1997)
Cancer Res.
, vol.57
, Issue.10
, pp. 1835-1840
-
-
Eguchi, Y.1
Shimizu, S.2
Tsujimoto, Y.3
-
99
-
-
0343618415
-
Metabolic depletion of ATP by fructose inversely controls CD95- And tumor necrosis factor receptor 1-mediated hepatic apoptosis
-
Latta, M.; Kunstle, G.; Leist, M.; Wendel, A. Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis. J. Exp. Med. 2000, 191(11), 1975-1985.
-
(2000)
J. Exp. Med.
, vol.191
, Issue.11
, pp. 1975-1985
-
-
Latta, M.1
Kunstle, G.2
Leist, M.3
Wendel, A.4
-
100
-
-
0014424849
-
Liver adenine nucleotides: Fructose-induced depletion and its effect on protein synthesis
-
Maenpaa, P. H.; Raivio, K. O.; Kekomaki, M. P. Liver adenine nucleotides: fructose-induced depletion and its effect on protein synthesis. Science 1968, 161(847), 1253-1254.
-
(1968)
Science
, vol.161
, Issue.847
, pp. 1253-1254
-
-
Maenpaa, P.H.1
Raivio, K.O.2
Kekomaki, M.P.3
-
101
-
-
49849121535
-
Depletion of liver adenine nucleotides induced by D-fructose. Dose-dependence and specificity of the fructose effect
-
Raivio, K. O.; Kekomaki, M. P.; Maenpaa, P. H. Depletion of liver adenine nucleotides induced by D-fructose. Dose-dependence and specificity of the fructose effect. Biochem. Pharmacol. 1969, 18(10), 2615-2624.
-
(1969)
Biochem. Pharmacol.
, vol.18
, Issue.10
, pp. 2615-2624
-
-
Raivio, K.O.1
Kekomaki, M.P.2
Maenpaa, P.H.3
-
102
-
-
0033400542
-
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death
-
Lemasters, J. J.; Qian, T.; Bradham, C. A.; Brenner, D. A.; Cascio, W. E.; Trost, L. C.; Nishimura, Y.; Nieminen, A. L.; Herman, B. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J. Bioenerg. Biomembr. 1999, 31(4), 305-319.
-
(1999)
J. Bioenerg. Biomembr.
, vol.31
, Issue.4
, pp. 305-319
-
-
Lemasters, J.J.1
Qian, T.2
Bradham, C.A.3
Brenner, D.A.4
Cascio, W.E.5
Trost, L.C.6
Nishimura, Y.7
Nieminen, A.L.8
Herman, B.9
-
103
-
-
0023742525
-
Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes
-
Gores, G. J.; Nieminen, A. L.; Fleishman, K. E.; Dawson, T. L.; Herman, B.; Lemasters, J. J. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. Am. J. Physiol. 1988, 255(3 Pt 1), C315-C322.
-
(1988)
Am. J. Physiol.
, vol.255
, Issue.3 PART 1
-
-
Gores, G.J.1
Nieminen, A.L.2
Fleishman, K.E.3
Dawson, T.L.4
Herman, B.5
Lemasters, J.J.6
-
104
-
-
0033556544
-
The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187
-
Qian, T.; Herman, B.; Lemasters, J. J. The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol. Appl. Pharmacol. 1999, 154(2), 117-125.
-
(1999)
Toxicol. Appl. Pharmacol.
, vol.154
, Issue.2
, pp. 117-125
-
-
Qian, T.1
Herman, B.2
Lemasters, J.J.3
-
105
-
-
0026531756
-
High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
-
Lienard, D.; Ewalenko, P.; Delmotte, J. J.; Renard, N.; Lejeune, F. J. High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J. Clin. Oncol. 1992, 10(1), 52-60.
-
(1992)
J. Clin. Oncol.
, vol.10
, Issue.1
, pp. 52-60
-
-
Lienard, D.1
Ewalenko, P.2
Delmotte, J.J.3
Renard, N.4
Lejeune, F.J.5
-
106
-
-
0028641633
-
Clinical experience with high-dose tumor necrosis factor alpha in regional therapy of advanced melanoma
-
Lejeune, F.; Lienard, D.; Eggermont, A.; Schraffordt Koops, H.; Kroon, B.; Gerain, J.; Rosenkaimer, F.; Schmitz P. Clinical experience with high-dose tumor necrosis factor alpha in regional therapy of advanced melanoma. Circ. Shock 1994, 43(4), 191-197.
-
(1994)
Circ. Shock
, vol.43
, Issue.4
, pp. 191-197
-
-
Lejeune, F.1
Lienard, D.2
Eggermont, A.3
Schraffordt Koops, H.4
Kroon, B.5
Gerain, J.6
Rosenkaimer, F.7
Schmitz, P.8
-
107
-
-
0030058843
-
Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: Results of a tumor necrosis factor dose-escalation study
-
Fraker, D. L.; Alexander, H. R.; Andrich, M.; Rosenberg, S. A. Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study. J. Clin. Oncol. 1996, 14(2), 479-489.
-
(1996)
J. Clin. Oncol.
, vol.14
, Issue.2
, pp. 479-489
-
-
Fraker, D.L.1
Alexander, H.R.2
Andrich, M.3
Rosenberg, S.A.4
-
108
-
-
0345596439
-
Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
-
Alexander, H. R. Jr.; Bartlett, D. L.; Libutti, S. K.; Fraker, D. L.; Moser, T.; Rosenberg, S. A. Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J. Clin. Oncol. 1998, 16(4), 1479-1489.
-
(1998)
J. Clin. Oncol.
, vol.16
, Issue.4
, pp. 1479-1489
-
-
Alexander Jr., H.R.1
Bartlett, D.L.2
Libutti, S.K.3
Fraker, D.L.4
Moser, T.5
Rosenberg, S.A.6
-
109
-
-
0004388350
-
Studies on the anti-tumour activity of p-di-(2-chloroethyl) aminophenylalanine (sarcolysine)
-
Larionov, L. F.; Shkodinskaja, E. N.; Troosheikina, V. I.; Khokhlov, A. S.; Vasina, O. S.; Novikova, M. A. Studies on the anti-tumour activity of p-di-(2-chloroethyl) aminophenylalanine (sarcolysine). Lancet 1955, 269(6882), 169-171.
-
(1955)
Lancet
, vol.269
, Issue.6882
, pp. 169-171
-
-
Larionov, L.F.1
Shkodinskaja, E.N.2
Troosheikina, V.I.3
Khokhlov, A.S.4
Vasina, O.S.5
Novikova, M.A.6
-
110
-
-
0029059542
-
Nitrogen mustard inhibits transcription and translation in a cell free system
-
Masta, A.; Gray, P. J.; Phillips, D. R. Nitrogen mustard inhibits transcription and translation in a cell free system. Nucl. Acids Res. 1995, 23(17), 3508-3515.
-
(1995)
Nucl. Acids Res.
, vol.23
, Issue.17
, pp. 3508-3515
-
-
Masta, A.1
Gray, P.J.2
Phillips, D.R.3
-
111
-
-
0024246023
-
The systemic administration of intravenous melphalan
-
Sarosy, G.; Leyland-Jones, B.; Soochan, P.; Cheson, B. D. The systemic administration of intravenous melphalan. J. Clin. Oncol. 1988, 6(11), 1768-1782.
-
(1988)
J. Clin. Oncol.
, vol.6
, Issue.11
, pp. 1768-1782
-
-
Sarosy, G.1
Leyland-Jones, B.2
Soochan, P.3
Cheson, B.D.4
-
112
-
-
3142516376
-
TNF-based isolated limb perfusion: A decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas
-
Grunhagen, D. J.; Brunstein, F.; ten Hagen, T. L.; van Geel, A. N.; de Wilt, J. H.; Eggermont, A. M. TNF-based isolated limb perfusion: a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas. Cancer Treat. Res. 2004, 120, 65-79.
-
(2004)
Cancer Treat. Res.
, vol.120
, pp. 65-79
-
-
Grunhagen, D.J.1
Brunstein, F.2
Ten Hagen, T.L.3
Van Geel, A.N.4
De Wilt, J.H.5
Eggermont, A.M.6
-
113
-
-
0035664781
-
Factors affecting survival after complete response to isolated limb perfusion in patients with in-transit melanoma
-
Zogakis, T. G.; Bartlett, D. L.; Libutti, S. K.; Liewehr, D. J.; Steinberg, S. M.; Fraker, D. L.; Alexander, H. R. Factors affecting survival after complete response to isolated limb perfusion in patients with in-transit melanoma. Ann. Surg. Oncol. 2001, 8(10), 771-778.
-
(2001)
Ann. Surg. Oncol.
, vol.8
, Issue.10
, pp. 771-778
-
-
Zogakis, T.G.1
Bartlett, D.L.2
Libutti, S.K.3
Liewehr, D.J.4
Steinberg, S.M.5
Fraker, D.L.6
Alexander, H.R.7
-
114
-
-
0141792648
-
Solid tumor therapy: Manipulation of the vasculature with TNF
-
ten Hagen, T. L.; Eggermont, A. M. Solid tumor therapy: manipulation of the vasculature with TNF. Technol. Cancer Res. Treat. 2003, 2(3), 195-203.
-
(2003)
Technol. Cancer Res. Treat.
, vol.2
, Issue.3
, pp. 195-203
-
-
Ten Hagen, T.L.1
Eggermont, A.M.2
-
115
-
-
1342288382
-
Tumor necrosis factor-alpha augmented tumor response in B16BL6 melanoma-bearing mice treated with stealth liposomal doxorubicin (Doxil) correlates with altered Doxil pharmacokinetics
-
Brouckaert, P.; Takahashi, N.; van Tiel, S. T.; Hostens, J.; Eggermont, A. M.; Seynhaeve, A. L.; Fiers, W.; ten Hagen, T. L. Tumor necrosis factor-alpha augmented tumor response in B16BL6 melanoma-bearing mice treated with stealth liposomal doxorubicin (Doxil) correlates with altered Doxil pharmacokinetics. Int. J. Cancer 2004, 109(3), 442-448.
-
(2004)
Int. J. Cancer
, vol.109
, Issue.3
, pp. 442-448
-
-
Brouckaert, P.1
Takahashi, N.2
Van Tiel, S.T.3
Hostens, J.4
Eggermont, A.M.5
Seynhaeve, A.L.6
Fiers, W.7
Ten Hagen, T.L.8
-
116
-
-
0025688912
-
Vascular permeability factor: A tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration
-
Clauss, M.; Gerlach, M.; Gerlach, H.; Brett, J.; Wang, F.; Familletti, P. C.; Pan, Y. C.; Olander, J. V.; Connolly, D. T.; Stern, D. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J. Exp. Med. 1990, 172(6), 1535-1545.
-
(1990)
J. Exp. Med.
, vol.172
, Issue.6
, pp. 1535-1545
-
-
Clauss, M.1
Gerlach, M.2
Gerlach, H.3
Brett, J.4
Wang, F.5
Familletti, P.C.6
Pan, Y.C.7
Olander, J.V.8
Connolly, D.T.9
Stern, D.10
-
117
-
-
0343962297
-
Tumour necrosis factor receptor I (p55) is upregulated on endothelial cells by exposure to the tumour-derived cytokine endothelial monocyte-activating polypeptide II (EMAP-II)
-
Berger, A. C.; Alexander, H. R.; Wu, P. C.; Tang, G.; Gnant, M. F.; Mixon, A.; Turner, E. S.; Libutti, S. K. Tumour necrosis factor receptor I (p55) is upregulated on endothelial cells by exposure to the tumour-derived cytokine endothelial monocyte-activating polypeptide II (EMAP-II). Cytokine 2000, 12(7), 992-1000.
-
(2000)
Cytokine
, vol.12
, Issue.7
, pp. 992-1000
-
-
Berger, A.C.1
Alexander, H.R.2
Wu, P.C.3
Tang, G.4
Gnant, M.F.5
Mixon, A.6
Turner, E.S.7
Libutti, S.K.8
-
118
-
-
0035148890
-
Endothelial monocyte activating polypeptide II (EMAP II) enhances the effect of TNF on tumor-associated vasculature
-
Kayton, M. L.; Libutti, S. K. Endothelial monocyte activating polypeptide II (EMAP II) enhances the effect of TNF on tumor-associated vasculature. Curr. Opin. Investig. Drugs 2001, 2(1), 136-138.
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, Issue.1
, pp. 136-138
-
-
Kayton, M.L.1
Libutti, S.K.2
-
119
-
-
0032894132
-
In vivo sensitivity of human melanoma to tumor necrosis factor (TNF)-alpha is determined by tumor production of the novel cytokine endothelial-monocyte activating polypeptide II (EMAPII)
-
Wu, P. C.; Alexander, H. R.; Huang, J.; Hwu, P.; Gnant, M.; Berger, A. C.; Turner, E.; Wilson, O.; Libutti, S. K. In vivo sensitivity of human melanoma to tumor necrosis factor (TNF)-alpha is determined by tumor production of the novel cytokine endothelial-monocyte activating polypeptide II (EMAPII). Cancer Res. 1999, 59(1), 205-212.
-
(1999)
Cancer Res.
, vol.59
, Issue.1
, pp. 205-212
-
-
Wu, P.C.1
Alexander, H.R.2
Huang, J.3
Hwu, P.4
Gnant, M.5
Berger, A.C.6
Turner, E.7
Wilson, O.8
Libutti, S.K.9
-
120
-
-
4444284590
-
Involvement of endothelial monocyte activating polypeptide II in tumor necrosis factor-alpha-based anti-cancer therapy
-
Lans, T. E.; Van Horssen, R.; Eggermont, A. M.; Ten Hagen, T. L. Involvement of endothelial monocyte activating polypeptide II in tumor necrosis factor-alpha-based anti-cancer therapy. Anticancer Res. 2004, 24(4), 2243-2248.
-
(2004)
Anticancer Res.
, vol.24
, Issue.4
, pp. 2243-2248
-
-
Lans, T.E.1
Van Horssen, R.2
Eggermont, A.M.3
Ten Hagen, T.L.4
-
121
-
-
0038724539
-
Vascular integrins: Pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis
-
Ruegg, C.; Mariotti, A. Vascular integrins: pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis. Cell Mol. Life Sci. 2003, 60(6), 1135-1157.
-
(2003)
Cell Mol. Life Sci.
, vol.60
, Issue.6
, pp. 1135-1157
-
-
Ruegg, C.1
Mariotti, A.2
-
122
-
-
0027970092
-
Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
-
O'Reilly, M. S.; Holmgren, L.; Shing, Y.; Chen, C.; Rosenthal, R. A.; Moses, M.; Lane, W. S.; Cao, Y.; Sage, E. H.; Folkman, J. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994, 79(2), 315-328.
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 315-328
-
-
O'Reilly, M.S.1
Holmgren, L.2
Shing, Y.3
Chen, C.4
Rosenthal, R.A.5
Moses, M.6
Lane, W.S.7
Cao, Y.8
Sage, E.H.9
Folkman, J.10
-
123
-
-
17444390815
-
Multiple forms of angiostatin induce apoptosis in endothelial cells
-
Lucas, R.; Holmgren, L.; Garcia, I.; Jimenez, B.; Mandriota, S. J.; Borlat, F.; Sim, B. K.; Wu, Z.; Grau, G. E.; Shing, Y.; Soff, G. A.; Bouck, N.; Pepper, M. S. Multiple forms of angiostatin induce apoptosis in endothelial cells. Blood 1998, 92(12), 4730-4741.
-
(1998)
Blood
, vol.92
, Issue.12
, pp. 4730-4741
-
-
Lucas, R.1
Holmgren, L.2
Garcia, I.3
Jimenez, B.4
Mandriota, S.J.5
Borlat, F.6
Sim, B.K.7
Wu, Z.8
Grau, G.E.9
Shing, Y.10
Soff, G.A.11
Bouck, N.12
Pepper, M.S.13
-
124
-
-
0032510801
-
Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD
-
Claesson-Welsh, L.; Welsh, M.; Ito, N.; Anand-Apte, B.; Soker, S.; Zetter, B.; O'Reilly, M.; Folkman, J.; Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc. Natl. Acad. Sci. USA 1998, 95(10), 5579-5583.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, Issue.10
, pp. 5579-5583
-
-
Claesson-Welsh, L.1
Welsh, M.2
Ito, N.3
Anand-Apte, B.4
Soker, S.5
Zetter, B.6
O'Reilly, M.7
Folkman, J.8
-
125
-
-
0043175171
-
Angiostatin(4.5)-mediated apoptosis of vascular endothelial cells
-
Hanford, H. A.; Wong, C. A.; Kassan, H.; Cundiff, D. L.; Chandel, N.; Underwood, S.; Mitchell, C. A.; Soff, G. A. Angiostatin(4.5)-mediated apoptosis of vascular endothelial cells. Cancer Res. 2003, 63(14), 4275-4280.
-
(2003)
Cancer Res.
, vol.63
, Issue.14
, pp. 4275-4280
-
-
Hanford, H.A.1
Wong, C.A.2
Kassan, H.3
Cundiff, D.L.4
Chandel, N.5
Underwood, S.6
Mitchell, C.A.7
Soff, G.A.8
-
126
-
-
0031454617
-
Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
-
O'Reilly, M. S.; Boehm, T.; Shing, Y.; Fukai, N.; Vasios, G.; Lane, W. S.; Flynn, E.; Birkhead, J. R.; Olsen, B. R.; Folkman, J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997, 88(2), 277-285.
-
(1997)
Cell
, vol.88
, Issue.2
, pp. 277-285
-
-
O'Reilly, M.S.1
Boehm, T.2
Shing, Y.3
Fukai, N.4
Vasios, G.5
Lane, W.S.6
Flynn, E.7
Birkhead, J.R.8
Olsen, B.R.9
Folkman, J.10
-
127
-
-
0033542129
-
Cloning, expression, and in vitro activity of human endostatin
-
Dhanabal, M.; Volk, R.; Ramchandran, R.; Simons, M.; Sukhatme, V. P. Cloning, expression, and in vitro activity of human endostatin. Biochem. Biophys. Res. Commun. 1999, 258(2), 345-352.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.258
, Issue.2
, pp. 345-352
-
-
Dhanabal, M.1
Volk, R.2
Ramchandran, R.3
Simons, M.4
Sukhatme, V.P.5
-
128
-
-
0024508087
-
Hepatic resection for colorectal liver metastases
-
Roh, M. S. Hepatic resection for colorectal liver metastases. Hematol. Oncol. Clin. North Am. 1989, 3(1), 171-181.
-
(1989)
Hematol. Oncol. Clin. North Am.
, vol.3
, Issue.1
, pp. 171-181
-
-
Roh, M.S.1
-
129
-
-
73049177706
-
Development of a technic for isolated perfusion of the liver
-
Ausman, R. K. Development of a technic for isolated perfusion of the liver. NY State J. Med. 1961, 61, 3993-3997.
-
(1961)
NY State J. Med.
, vol.61
, pp. 3993-3997
-
-
Ausman, R.K.1
-
130
-
-
0032421016
-
High-dose mitomycin C in isolated hyperthermic liver perfusion for unresectable liver metastases
-
Oldhafer, K. J.; Frerker, M. K.; Lang, H.; Fauler, J.; Flemming, P.; Schmoll, E.; Nadalin, S.; Moreno, L.; Pichlmayr, R. High-dose mitomycin C in isolated hyperthermic liver perfusion for unresectable liver metastases. J. Invest. Surg. 1998, 11(6), 393-400.
-
(1998)
J. Invest. Surg.
, vol.11
, Issue.6
, pp. 393-400
-
-
Oldhafer, K.J.1
Frerker, M.K.2
Lang, H.3
Fauler, J.4
Flemming, P.5
Schmoll, E.6
Nadalin, S.7
Moreno, L.8
Pichlmayr, R.9
-
131
-
-
0028020609
-
Percutaneous hepatic vein isolation and high-dose hepatic arterial infusion chemotherapy for unresectable liver tumors
-
Ravikumar, T. S.; Pizzorno, G.; Bodden, W.; Marsh, J.; Strair, R.; Pollack, J.; Hendler, R.; Hanna, J.; D'Andrea, E. Percutaneous hepatic vein isolation and high-dose hepatic arterial infusion chemotherapy for unresectable liver tumors. J. Clin. Oncol. 1994, 12(12), 2723-2736.
-
(1994)
J. Clin. Oncol.
, vol.12
, Issue.12
, pp. 2723-2736
-
-
Ravikumar, T.S.1
Pizzorno, G.2
Bodden, W.3
Marsh, J.4
Strair, R.5
Pollack, J.6
Hendler, R.7
Hanna, J.8
D'Andrea, E.9
-
132
-
-
0034896632
-
Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion
-
Lans, T. E.; Bartlett, D. L.; Libutti, S. K.; Gnant, M. F.; Liewehr, D. J.; Venzon, D. J.; Turner, E. M.; Alexander, H. R. Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion. Clin. Cancer Res. 2001, 7(4), 784-790.
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.4
, pp. 784-790
-
-
Lans, T.E.1
Bartlett, D.L.2
Libutti, S.K.3
Gnant, M.F.4
Liewehr, D.J.5
Venzon, D.J.6
Turner, E.M.7
Alexander, H.R.8
-
133
-
-
0036214346
-
Transarterial perfusion of liver metastases
-
Weinreich, D. M.; Alexander, H. R. Transarterial perfusion of liver metastases. Semin. Oncol. 2002, 29(2), 136-144.
-
(2002)
Semin. Oncol.
, vol.29
, Issue.2
, pp. 136-144
-
-
Weinreich, D.M.1
Alexander, H.R.2
-
134
-
-
0345596439
-
Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
-
Alexander, H. R. Jr.; Bartlett, D. L.; Libutti, S. K.; Fraker, D. L.; Moser, T.; Rosenberg, S. A. Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J. Clin. Oncol. 1998, 16(4), 1479-1489.
-
(1998)
J. Clin. Oncol.
, vol.16
, Issue.4
, pp. 1479-1489
-
-
Alexander Jr., H.R.1
Bartlett, D.L.2
Libutti, S.K.3
Fraker, D.L.4
Moser, T.5
Rosenberg, S.A.6
-
135
-
-
0031688717
-
Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: Requirement for type 1 but not type 2 receptor
-
Yamada, Y.; Webber, E. M.; Kirillova, I.; Peschon, J. J.; Fausto, N. Analysis of liver regeneration in mice lacking type 1 or type 2 tumor necrosis factor receptor: requirement for type 1 but not type 2 receptor. Hepatology 1998, 28(4), 959-970.
-
(1998)
Hepatology
, vol.28
, Issue.4
, pp. 959-970
-
-
Yamada, Y.1
Webber, E.M.2
Kirillova, I.3
Peschon, J.J.4
Fausto, N.5
-
136
-
-
0034684651
-
Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice
-
Knight, B.; Yeoh, G. C.; Husk, K. L.; Ly, T.; Abraham, L. J.; Yu, C.; Rhim, J. A.; Fausto N. Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice. J. Exp. Med. 2000, 192(12), 1809-1818.
-
(2000)
J. Exp. Med.
, vol.192
, Issue.12
, pp. 1809-1818
-
-
Knight, B.1
Yeoh, G.C.2
Husk, K.L.3
Ly, T.4
Abraham, L.J.5
Yu, C.6
Rhim, J.A.7
Fausto, N.8
-
137
-
-
0033710992
-
The role of tumor necrosis factor alpha in chemical-induced hepatotoxicity
-
Luster, M. I.; Simeonova, P. P.; Gallucci, R. M.; Bruccoleri, A.; Blazka, M. E.; Yucesoy, B.; Matheson, J. M. The role of tumor necrosis factor alpha in chemical-induced hepatotoxicity. Ann. NY Acad. Sci. 2000, 919, 214-220.
-
(2000)
Ann. NY Acad. Sci.
, vol.919
, pp. 214-220
-
-
Luster, M.I.1
Simeonova, P.P.2
Gallucci, R.M.3
Bruccoleri, A.4
Blazka, M.E.5
Yucesoy, B.6
Matheson, J.M.7
-
138
-
-
0035675083
-
The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride
-
Simeonova, P. P.; Gallucci, R. M.; Hulderman, T.; Wilson, R.; Kommineni, C.; Rao, M.; Luster, M. I. The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride. Toxicol. Appl. Pharmacol. 2001, 177(2), 112-120.
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.177
, Issue.2
, pp. 112-120
-
-
Simeonova, P.P.1
Gallucci, R.M.2
Hulderman, T.3
Wilson, R.4
Kommineni, C.5
Rao, M.6
Luster, M.I.7
-
139
-
-
0036307759
-
Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production
-
Enomoto, N.; Takei, Y.; Hirose, M.; Ikejima, K.; Miwa, H.; Kitamura, T.; Sato, N. Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production. Gastroenterology 2002, 123(1), 291-300.
-
(2002)
Gastroenterology
, vol.123
, Issue.1
, pp. 291-300
-
-
Enomoto, N.1
Takei, Y.2
Hirose, M.3
Ikejima, K.4
Miwa, H.5
Kitamura, T.6
Sato, N.7
-
140
-
-
0033980632
-
Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor
-
Sharma, R. P.; Bhandari, N.; Riley, R. T.; Voss, K. A.; Meredith, F. I. Tolerance to fumonisin toxicity in a mouse strain lacking the P75 tumor necrosis factor receptor. Toxicology 2000, 143(2), 183-194.
-
(2000)
Toxicology
, vol.143
, Issue.2
, pp. 183-194
-
-
Sharma, R.P.1
Bhandari, N.2
Riley, R.T.3
Voss, K.A.4
Meredith, F.I.5
-
141
-
-
23844446098
-
Kupffer cell expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors
-
in press
-
Kresse, M.; Latta, M.; Künstle, G.; Riehle, H.-M.; van Rooijen, N.; Hentze, H.; Tiegs, G.; Biburger, M.; Lucas, R.; Wendel, A. Kupffer cell expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors. J. Immunol. 2005, in press.
-
(2005)
J. Immunol.
-
-
Kresse, M.1
Latta, M.2
Künstle, G.3
Riehle, H.-M.4
Van Rooijen, N.5
Hentze, H.6
Tiegs, G.7
Biburger, M.8
Lucas, R.9
Wendel, A.10
-
142
-
-
0023267422
-
Detection of DNA damage in individual cells by flow cytometric analysis using anti-DNA monoclonal antibody
-
Frankfurt, O. S. Detection of DNA damage in individual cells by flow cytometric analysis using anti-DNA monoclonal antibody. Exp. Cell Res. 1987 170(2), 369-380.
-
(1987)
Exp. Cell Res.
, vol.170
, Issue.2
, pp. 369-380
-
-
Frankfurt, O.S.1
-
143
-
-
0023755604
-
Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells
-
Garcia, S. T.; McQuillan, A.; Panasci, L. Correlation between the cytotoxicity of melphalan and DNA crosslinks as detected by the ethidium bromide fluorescence assay in the F1 variant of B16 melanoma cells. Biochem. Pharmacol. 1988, 37(16), 3189-3192.
-
(1988)
Biochem. Pharmacol.
, vol.37
, Issue.16
, pp. 3189-3192
-
-
Garcia, S.T.1
McQuillan, A.2
Panasci, L.3
-
144
-
-
0025201941
-
Endotoxin-induced cytokine gene expression in vivo. II. Regulation of tumor necrosis factor and interleukin-1 alpha/beta expression and suppression
-
Ulich, T. R.; Guo, K. Z.; Irwin, B.; Remick, D. G.; Davatelis, G. N. Endotoxin-induced cytokine gene expression in vivo. II. Regulation of tumor necrosis factor and interleukin-1 alpha/beta expression and suppression. Am. J. Pathol. 1990, 137(5), 1173-1185.
-
(1990)
Am. J. Pathol.
, vol.137
, Issue.5
, pp. 1173-1185
-
-
Ulich, T.R.1
Guo, K.Z.2
Irwin, B.3
Remick, D.G.4
Davatelis, G.N.5
-
145
-
-
0036284788
-
HSP70 protects against TNF-induced lethal inflammatory shock
-
Van Molle, W.; Wielockx, B.; Mahieu, T.; Takada, M.; Taniguchi, T.; Sekikawa, K.; Libert, C. HSP70 protects against TNF-induced lethal inflammatory shock. Immunity 2002, 16(5), 685-695.
-
(2002)
Immunity
, vol.16
, Issue.5
, pp. 685-695
-
-
Van Molle, W.1
Wielockx, B.2
Mahieu, T.3
Takada, M.4
Taniguchi, T.5
Sekikawa, K.6
Libert, C.7
-
146
-
-
0014178728
-
Fructokinase, Triokinase and Aldolase in liver tumors of the rat
-
Adelmann, R. C.; Morris, H. P.; Weinhouse, S. Fructokinase, Triokinase and Aldolase in liver tumors of the rat. Cancer Res. 1967, 27, 2408-2413.
-
(1967)
Cancer Res.
, vol.27
, pp. 2408-2413
-
-
Adelmann, R.C.1
Morris, H.P.2
Weinhouse, S.3
|