The T cell activation marker CD150 can be used to identify alloantigen-activated CD4+25+ regulatory T cells

Cellular Immunology

Volumn 227, Issue 2, 2004, Pages 129-139

  Browning, Meghen B ^a   Woodliff, Jeffrey E ^a   Konkol, Marja C ^a   Pati, Nirupma T ^a   Ghosh, Soumitra ^a   Truitt, Robert L ^a   Johnson, Bryon D ^a  

^a CHILDREN S HOSPITAL OF WISCONSIN   (United States)

Author keywords

CD150; CD4+25+ cells; Graft vs. host disease; Human regulatory T cells

Indexed keywords

ALLOANTIGEN; BIOLOGICAL MARKER; CD150 ANTIGEN; CD4 ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ANTIGEN PURIFICATION; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANTIGENS, CD; ANTIGENS, CD4; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULINS; ISOANTIGENS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CELL SURFACE; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTES;

EID: 2342634326     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellimm.2004.03.003     Document Type: Article

References (40)

1. Sakaguchi S., Sakaguchi N., Asano M., Itoh M., Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1995;1151-1164
2. Takahashi T., Kuniyasu Y., Toda M., Sakaguchi N., Itoh M., Iwata M., Shimizu J., Sakaguchi S. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10:1998;1969-1980
3. + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:1998;287-296
4. Papiernik M., de Moraes M.L., Pontoux C., Vasseur F., Penit C. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int. Immunol. 10:1998;371-378
5. Stephens L.A., Mottet C., Mason D., Powrie F., Human F. CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur. J. Immunol. 31:2001;1247-1254
6. Levings M.K., Sangregorio R., Roncarlo M.G. Human CD25+CD4+ T regulatory cells suppress naïve and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193:2001;1295-1301
7. Jonuleit H., Schmitt E., Stassen M., Tuettenberg A., Knop J., Enk A.H. Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193:2001;1285-1294
8. Ng W.F., Duggan P.J., Ponchel F., Matarese G., Lombardi G., Edwards A.D., Isaacs J.D., Lechler R.I. Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells. Blood. 98:2001;2736-2744
9. high regulatory cells in human peripheral blood. J. Immunol. 167:2001;1245-1253
10. Asano M., Toda M., Sakaguchi N., Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184:1996;387-396
11. Taylor P.A., Lees C.J., Blazar B.R. The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality. Blood. 99:2002;3493-3499
12. Kingsley C.I., Karim M., Bushell A.R., Wood K.J. CD25(+)CD4(+) regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 168:2002;1080-1086
13. McHugh R.S., Shevach E.M. The role of suppressor T cells in regulation of immune responses. J. Allergy Clin. Immunol. 110:2002;693-702
14. Onizuke S., Tawara I., Shimizu J., Sakaguchi S., Fujita T., Nakayama E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 59:1999;3128-3133
15. Shimizu J., Yamazaki S., Sakaguchi S. Induction of tumor immunity by removing CD25+CD4- cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163:1999;5211-5218
16. Johnson B.D., Konkol M.C., Truitt R.L. CD25+ immunoregulatory T-cells of donor origin suppress alloreactivity after BMT. Biol. Blood Marrow Transpl. 8:2002;525-535
17. Hoffman P., Ermann J., Edinger M., Fathman C.G., Strober S. Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. 196:2002;389-399
18. + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation, Nat. Med., 2003, pub. online
19. Ermann J., Szanya V., Ford G.S., Paragas V., Fathman C.G., Lejon K. CD4(+)CD25(+) T cells facilitate the induction of T cell anergy. J. Immunol. 167:2001;4271-4275
20. + regulatory T cells from human peripheral blood. J. Immunol. 166:2001;7282-7289
21. Papiernik M. Natural CD4+ CD25+ regulatory T cells. Their role in the control of superantigen responses. Immunol. Rev. 182:2001;180-189
22. + immunoregulatory T cells is antigen nonspecific. J. Immunol. 164:2000;183-190
23. Shevach E.M. Certified Professionals: CD4+CD25+ suppressor T cells. J. Exp. Med. 193:2001;F41-F45
24. + regulatory T cells inhibit immune-mediated transgene rejection. Blood. 102:2003;4326-4328
25. + T cells lyse antigen-presenting B cells by fas-fas ligand interaction in an epitope-specific manner. J. Immunol. 171:2003;4604-4612
26. - precursors. J. Immunol. 169:2002;4183-4189
27. - regulatory T cells. Proc. Natl. Acad. Sci. USA. 99:2002;13031-13036
28. + immunoregulatory T cells that control autoimmune diabetes. Immunity. 12:2000;431-440
29. Shimizu J., Yamazaki S., Takahashi T., Ishida Y., Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunologic self-tolerance. Nat. Immunol. 3:2002;135-142
30. Dieckmann D., Plottner H., Berchtold S., Berger T., Schuler G. Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood. J. Exp. Med. 193:2001;1303-1310
31. - T cells. Ann. N. Y. Acad. Sci. 1005:2003;279-283
32. Tatsuo H., Ono N., Tanaka K., Yanagi Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature. 406:2000;893-897
33. Dorig R.E., Marcil A., Chopra A., Richardson C.D. The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell. 75:1993;295-305
34. Sidorenko S.P., Clark E.A. Characterization of a cell surface glycoprotein IPO-3, expressed on activated human B and T lymphocytes. J. Immunol. 151:1993;4614-4624
35. Aversa G., Carballido J., Punnonen J., Chang C.C., Hauser T., Cocks B.G., De Vries J.E. SLAM and its role in T cell activation and Th cell responses. Immunol. Cell Biol. 75:1997;202-205
36. Cocks B.G., Chang C.-C.J., Carballido J.M., Yssel H., de Vries J.E., Aversa G. A novel receptor involved in T-cell activation. Nature. 376:1995;260-263
37. -mediated costimulation. Blood. 99:2002;957-965
38. Morra M., Simarro-Grande M., Martin M., Chen A.S., Lanyi A., Silander O., Calpe S., Davis J., Pawson T., Eck M.J., Sumegi J., Engel P., Li S.C., Terhorst C. Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients. J. Biol. Chem. 276:2001;36809-36816
39. Levine B.L., Bernstein W.B., Connors M., Craighead N., Lindsten T., Thompson C.B., June C.H. Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells. J. Immunol. 159:1997;5921-5930
40. Baecher-Allen C., Viglietta V., Hafler D.A. Inhibition of human CD4(+)CD25(+high) regulatory T cell function. J. Immunol. 169:2002;6210-6217