-
1
-
-
0019736999
-
Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture
-
Ackerman GE, Smith ME, Mendelson CR, MacDonald PC & Simpson ER 1981 Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture. Journal of Clinical Endocrinology and Metabolism 53 412-417.
-
(1981)
Journal of Clinical Endocrinology and Metabolism
, vol.53
, pp. 412-417
-
-
Ackerman, G.E.1
Smith, M.E.2
Mendelson, C.R.3
MacDonald, P.C.4
Simpson, E.R.5
-
2
-
-
0029616317
-
Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR
-
Agarwal VR, Bulun SE & Simpson ER 1995 Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR. Molecular and Cellular Probes 9 453-464.
-
(1995)
Molecular and Cellular Probes
, vol.9
, pp. 453-464
-
-
Agarwal, V.R.1
Bulun, S.E.2
Simpson, E.R.3
-
3
-
-
0030729211
-
Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells
-
Arts J, Kuiper GG, Janssen JM, Gustafsson JA, Lowik CW, Pols HA & van Leeuwen JP 1997 Differential expression of estrogen receptors alpha and beta mRNA during differentiation of human osteoblast SV-HFO cells. Endocrinology 138 5067-5070.
-
(1997)
Endocrinology
, vol.138
, pp. 5067-5070
-
-
Arts, J.1
Kuiper, G.G.2
Janssen, J.M.3
Gustafsson, J.A.4
Lowik, C.W.5
Pols, H.A.6
van Leeuwen, J.P.7
-
5
-
-
0025950241
-
Age-dependent responsiveness of rabbit and human cartilage cells to sex steroids in vitro
-
Blanchard O, Tsagris L, Rappaport R, Duval-Beaupere G & Corvol M 1991 Age-dependent responsiveness of rabbit and human cartilage cells to sex steroids in vitro. Journal of Steroid Biochemistry and Molecular Biology 40 711-716.
-
(1991)
Journal of Steroid Biochemistry and Molecular Biology
, vol.40
, pp. 711-716
-
-
Blanchard, O.1
Tsagris, L.2
Rappaport, R.3
Duval-Beaupere, G.4
Corvol, M.5
-
6
-
-
0020730383
-
Effect of glucocorticoids on type I collagen synthesis, alkaline phosphatase activity, and deoxyribonucleic acid content in cultured rat calvariae
-
Canalis E 1983 Effect of glucocorticoids on type I collagen synthesis, alkaline phosphatase activity, and deoxyribonucleic acid content in cultured rat calvariae. Endocrinology 112 931-939.
-
(1983)
Endocrinology
, vol.112
, pp. 931-939
-
-
Canalis, E.1
-
7
-
-
0030797569
-
Effect of testosterone and estradiol in a man with aromatase deficiency
-
Carani C, Qin K, Simoni M, Faustini-Fustini M, Serpente S, Boyd J, Korach KS & Simpson ER 1997 Effect of testosterone and estradiol in a man with aromatase deficiency. New England Journal of Medicine 337 91-95.
-
(1997)
New England Journal of Medicine
, vol.337
, pp. 91-95
-
-
Carani, C.1
Qin, K.2
Simoni, M.3
Faustini-Fustini, M.4
Serpente, S.5
Boyd, J.6
Korach, K.S.7
Simpson, E.R.8
-
8
-
-
0027478854
-
Establishment and characterization of a simian virus 40-immortalized osteoblastic cell line from normal human bone
-
Chiba H, Sawada N, Ono T, Ishii S & Mori M 1993 Establishment and characterization of a simian virus 40-immortalized osteoblastic cell line from normal human bone. Japanese Journal of Cancer Research 84 290-297.
-
(1993)
Japanese Journal of Cancer Research
, vol.84
, pp. 290-297
-
-
Chiba, H.1
Sawada, N.2
Ono, T.3
Ishii, S.4
Mori, M.5
-
9
-
-
0037036456
-
Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes
-
Clyne CD, Speed CJ, Zhou J & Simpson ER 2002 Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes. Journal of Biological Chemistry 277 20591-20397.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 20397-20591
-
-
Clyne, C.D.1
Speed, C.J.2
Zhou, J.3
Simpson, E.R.4
-
10
-
-
0038778339
-
Regulation of CYP19 gene expression in primary human osteoblasts: Effects of vitamin D and other treatments
-
Enjuanes A, Garcia-Giralt N, Supervia A, Nogues X, Mellibovsky L, Carbonell J, Grinberg D, Balcells S & Diez-Perez A 2003 Regulation of CYP19 gene expression in primary human osteoblasts: effects of vitamin D and other treatments. European Journal of Endocrinology 148 519-526.
-
(2003)
European Journal of Endocrinology
, vol.148
, pp. 519-526
-
-
Enjuanes, A.1
Garcia-Giralt, N.2
Supervia, A.3
Nogues, X.4
Mellibovsky, L.5
Carbonell, J.6
Grinberg, D.7
Balcells, S.8
Diez-Perez, A.9
-
11
-
-
0033083071
-
Gene expression during differentiation of human dendritic cells from cord blood cd34 stem cells
-
Fisher GM, Iqball S & Knight SC 1999 Gene expression during differentiation of human dendritic cells from cord blood cd34 stem cells. Cytokine 11 111-117.
-
(1999)
Cytokine
, vol.11
, pp. 111-117
-
-
Fisher, G.M.1
Iqball, S.2
Knight, S.C.3
-
12
-
-
0033536565
-
Oncostatin M: Signal transduction and biological activity
-
Gomez-Lechon MJ 1999 Oncostatin M: signal transduction and biological activity. Life Sciences 65 2019-2030.
-
(1999)
Life Sciences
, vol.65
, pp. 2019-2030
-
-
Gomez-Lechon, M.J.1
-
13
-
-
0034504525
-
Estrogen, bone, growth and sex: A sea change in conventional wisdom
-
Grumbach MM 2000 Estrogen, bone, growth and sex: a sea change in conventional wisdom. Journal of Pediatric Endocrinology and Metabolism 13 Suppl 6 1439-1455.
-
(2000)
Journal of Pediatric Endocrinology and Metabolism
, vol.13
, Issue.SUPPL. 6
, pp. 1439-1455
-
-
Grumbach, M.M.1
-
14
-
-
0033790375
-
gp 130 Cytokine family and bone cells
-
Heymann D & Rousselle AV 2000 gp 130 Cytokine family and bone cells. Cytokine 12 1455-1468.
-
(2000)
Cytokine
, vol.12
, pp. 1455-1468
-
-
Heymann, D.1
Rousselle, A.V.2
-
15
-
-
0035811548
-
Gene expression of glucocorticoid receptor alpha and beta in giant cell tumour of bone: Evidence of glucocorticoid-stimulated osteoclastogenesis by stromal-like tumour cells
-
Huang L, Xu J, Kumta SM & Zheng MH 2001 Gene expression of glucocorticoid receptor alpha and beta in giant cell tumour of bone: evidence of glucocorticoid-stimulated osteoclastogenesis by stromal-like tumour cells. Molecular and Cellular Endocrinology 181 199-206.
-
(2001)
Molecular and Cellular Endocrinology
, vol.181
, pp. 199-206
-
-
Huang, L.1
Xu, J.2
Kumta, S.M.3
Zheng, M.H.4
-
16
-
-
0028821789
-
Glucocorticoids induce mineralization coupled with bone protein expression without influence on growth of a human osteoblastic cell line
-
Iba K, Chiba H, Sawada N, Hirota S, Ishii S & Mori M 1995 Glucocorticoids induce mineralization coupled with bone protein expression without influence on growth of a human osteoblastic cell line. Cell Structure and Function 20 319-330.
-
(1995)
Cell Structure and Function
, vol.20
, pp. 319-330
-
-
Iba, K.1
Chiba, H.2
Sawada, N.3
Hirota, S.4
Ishii, S.5
Mori, M.6
-
17
-
-
0033485478
-
Estradiol formation by human osteoblasts via multiple pathways: Relation with osteoblast function
-
Janssen JM, Bland R, Hewison M, Coughtrie MW, Sharp S, Arts J, Pols HA & van Leeuwen JP 1999 Estradiol formation by human osteoblasts via multiple pathways: relation with osteoblast function. Journal of Cellular Biochemistry 75 528-537.
-
(1999)
Journal of Cellular Biochemistry
, vol.75
, pp. 528-537
-
-
Janssen, J.M.1
Bland, R.2
Hewison, M.3
Coughtrie, M.W.4
Sharp, S.5
Arts, J.6
Pols, H.A.7
van Leeuwen, J.P.8
-
18
-
-
0030712149
-
Aromatase cytochrome P450 transcripts are detected in fractured human bone but not in normal skeletal tissue
-
Lea CK, Ebrahim, H, Tennant S & Flanagan AM 1997 Aromatase cytochrome P450 transcripts are detected in fractured human bone but not in normal skeletal tissue. Bone 21 433-440.
-
(1997)
Bone
, vol.21
, pp. 433-440
-
-
Lea, C.K.1
Ebrahim, H.2
Tennant, S.3
Flanagan, A.M.4
-
19
-
-
0028918381
-
Developmental abnormalities in mice transgenic for bovine oncostatin M
-
Malik N, Haugen HS, Modrell B, Shoyab M & Clegg CH 1995 Developmental abnormalities in mice transgenic for bovine oncostatin M. Molecular and Cellular Biology 15 2349-2358.
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 2349-2358
-
-
Malik, N.1
Haugen, H.S.2
Modrell, B.3
Shoyab, M.4
Clegg, C.H.5
-
20
-
-
17744379150
-
Polymorphism of the aromatase gene in postmenopausal Italian women: Distribution and correlation with bone mass and fracture risk
-
Masi L, Becherini L, Gennari L, Amedei A, Colli E, Falchetti A, Farci M, Silvestri S, Gonnelli S & Brandi ML 2001 Polymorphism of the aromatase gene in postmenopausal Italian women: distribution and correlation with bone mass and fracture risk. Journal of Clinical Endocrinology and Metabolism 86 2263-2269.
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, pp. 2263-2269
-
-
Masi, L.1
Becherini, L.2
Gennari, L.3
Amedei, A.4
Colli, E.5
Falchetti, A.6
Farci, M.7
Silvestri, S.8
Gonnelli, S.9
Brandi, M.L.10
-
21
-
-
0034810949
-
Sex- and age-related response to aromatase deficiency in bone
-
Miyaura C, Toda K, Inada M, Ohshiba T, Matsumoto C, Okada T, Ito M, Shizuta Y & Ito A 2001 Sex- and age-related response to aromatase deficiency in bone. Biochemical and Biophysical Research Communications 280 1062-1068.
-
(2001)
Biochemical and Biophysical Research Communications
, vol.280
, pp. 1062-1068
-
-
Miyaura, C.1
Toda, K.2
Inada, M.3
Ohshiba, T.4
Matsumoto, C.5
Okada, T.6
Ito, M.7
Shizuta, Y.8
Ito, A.9
-
22
-
-
0028792229
-
Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
-
Morishima A, Grumbach MM, Simpson ER, Fisher C & Qin K 1995 Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. Journal of Clinical Endocrinology and Metabolism 80 3689-3698.
-
(1995)
Journal of Clinical Endocrinology and Metabolism
, vol.80
, pp. 3689-3698
-
-
Morishima, A.1
Grumbach, M.M.2
Simpson, E.R.3
Fisher, C.4
Qin, K.5
-
23
-
-
0031154045
-
Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450 arom gene: Impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood
-
Mullis PE, Yoshimura N, Kuhlmann B, Lippuner K, Jaeger P & Harada H 1997 Aromatase deficiency in a female who is compound heterozygote for two new point mutations in the P450 arom gene: impact of estrogens on hypergonadotropic hypogonadism, multicystic ovaries, and bone densitometry in childhood. Journal of Clinical Endocrinology and Metabolism 82 1739-1745.
-
(1997)
Journal of Clinical Endocrinology and Metabolism
, vol.82
, pp. 1739-1745
-
-
Mullis, P.E.1
Yoshimura, N.2
Kuhlmann, B.3
Lippuner, K.4
Jaeger, P.5
Harada, H.6
-
24
-
-
0029133122
-
Aromatase in bone cell: Association with osteoporosis in postmenopausal women
-
Nawata H, Tanaka S, Tanaka S, Takayanagi R, Sakai Y, Yanase T, Ikuyama S & Haji M 1995 Aromatase in bone cell: association with osteoporosis in postmenopausal women. Journal of Steroid Biochemishy and Molecular Biology 53 165-174.
-
(1995)
Journal of Steroid Biochemishy and Molecular Biology
, vol.53
, pp. 165-174
-
-
Nawata, H.1
Tanaka, S.2
Tanaka, S.3
Takayanagi, R.4
Sakai, Y.5
Yanase, T.6
Ikuyama, S.7
Haji, M.8
-
25
-
-
0034007390
-
Bone has a sexually dimorphic response to aromatase deficiency
-
Oz OK, Zerwekh JE, Fisher C, Graves K, Nanu L, Millsaps R & Simpson ER 2000 Bone has a sexually dimorphic response to aromatase deficiency. Journal of Bone and Mineral Research 15 507-514.
-
(2000)
Journal of Bone and Mineral Research
, vol.15
, pp. 507-514
-
-
Oz, O.K.1
Zerwekh, J.E.2
Fisher, C.3
Graves, K.4
Nanu, L.5
Millsaps, R.6
Simpson, E.R.7
-
26
-
-
0034790349
-
Expression of aromatase in the human growth plate
-
Oz OK, Millsaps R, Welch R, Birch J & Zerwekh JE 2001 Expression of aromatase in the human growth plate. Journal of Molecular Endocrinology 27 249-253.
-
(2001)
Journal of Molecular Endocrinology
, vol.27
, pp. 249-253
-
-
Oz, O.K.1
Millsaps, R.2
Welch, R.3
Birch, J.4
Zerwekh, J.E.5
-
28
-
-
0031712804
-
Intratumoral aromatase in human breast, endometrial, and ovarian malignancies
-
Sasano H & Harada N 1998 Intratumoral aromatase in human breast, endometrial, and ovarian malignancies. Endocrine Reviews 19 593-607.
-
(1998)
Endocrine Reviews
, vol.19
, pp. 593-607
-
-
Sasano, H.1
Harada, N.2
-
29
-
-
0030800535
-
Aromatase in human bone tissue
-
Sasano H, Uzuki M, Sawai T, Nagura H, Matsunaga G, Kashimoto O & Harada N 1997 Aromatase in human bone tissue. Journal of Bone and Mineral Research 12 1416-1423.
-
(1997)
Journal of Bone and Mineral Research
, vol.12
, pp. 1416-1423
-
-
Sasano, H.1
Uzuki, M.2
Sawai, T.3
Nagura, H.4
Matsunaga, G.5
Kashimoto, O.6
Harada, N.7
-
31
-
-
0034751150
-
A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the Human Genome Project
-
Sebastian S & Bulun SE 2001 A highly complex organization of the regulatory region of the human CYP19 (aromatase) gene revealed by the Human Genome Project. Journal of Clinical Endocrinology and Metabolism 86 4600-4602.
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, pp. 4600-4602
-
-
Sebastian, S.1
Bulun, S.E.2
-
32
-
-
0029930671
-
Osteoblast cells (MG-63 and HOS) have aromatase and 5 alpha-reductase activities
-
Shimodaira K, Fujikawa H, Okura F, Shimizu Y, Saito H & Yanaihara T 1996 Osteoblast cells (MG-63 and HOS) have aromatase and 5 alpha-reductase activities. Biochemistry and Molecular Biology International 39 109-116.
-
(1996)
Biochemistry and Molecular Biology International
, vol.39
, pp. 109-116
-
-
Shimodaira, K.1
Fujikawa, H.2
Okura, F.3
Shimizu, Y.4
Saito, H.5
Yanaihara, T.6
-
34
-
-
0034711862
-
TGF-betal stimulates expression of the aromatase (C.YP19) gene in human osteoblast-like cells and THP-1 cells
-
Shozu M, Zhao Y & Simpson ER 2000 TGF-betal stimulates expression of the aromatase (C.YP19) gene in human osteoblast-like cells and THP-1 cells. Molecular and Cellular Endocrinology 160 123-133.
-
(2000)
Molecular and Cellular Endocrinology
, vol.160
, pp. 123-133
-
-
Shozu, M.1
Zhao, Y.2
Simpson, E.R.3
-
35
-
-
0033939017
-
The role of local estrogen biosynthesis in males and females
-
Simpson E, Rubin G, Clyne C, Robertson K, O'Donnell L, Jones M & Davis S 2000 The role of local estrogen biosynthesis in males and females. Trends in Endocrinology and Metabolism 11 184-188.
-
(2000)
Trends in Endocrinology and Metabolism
, vol.11
, pp. 184-188
-
-
Simpson, E.1
Rubin, G.2
Clyne, C.3
Robertson, K.4
O'Donnell, L.5
Jones, M.6
Davis, S.7
-
36
-
-
0034749898
-
Minireview: Aromatase and the regulation of estrogen biosynthesis - Some new perspectives
-
Simpson ER & Davis SR 2001 Minireview: aromatase and the regulation of estrogen biosynthesis - some new perspectives. Endocrinology 142 4589-4594.
-
(2001)
Endocrinology
, vol.142
, pp. 4589-4594
-
-
Simpson, E.R.1
Davis, S.R.2
-
37
-
-
0030630195
-
Aromatase expression in health and disease
-
Simpson ER, Zhao Y, Agarwal VR, Michael MD, Bulun SE, Hinshelwood MM, Graham-Lorence S, Sun T, Fisher CR, Qin K & Mendelson CR 1997 Aromatase expression in health and disease. Recent Progress in Hormone Research 52 185-213.
-
(1997)
Recent Progress in Hormone Research
, vol.52
, pp. 185-213
-
-
Simpson, E.R.1
Zhao, Y.2
Agarwal, V.R.3
Michael, M.D.4
Bulun, S.E.5
Hinshelwood, M.M.6
Graham-Lorence, S.7
Sun, T.8
Fisher, C.R.9
Qin, K.10
Mendelson, C.R.11
-
38
-
-
0036193893
-
Aromatase - A brief overview
-
Simpson ER, Clyne C, Rubin G, Boon WC, Robertson K, Britt K, Speed C & Jones M 2002 Aromatase - a brief overview. Annual Review of Physiology 64 93-127.
-
(2002)
Annual Review of Physiology
, vol.64
, pp. 93-127
-
-
Simpson, E.R.1
Clyne, C.2
Rubin, G.3
Boon, W.C.4
Robertson, K.5
Britt, K.6
Speed, C.7
Jones, M.8
-
39
-
-
0028143234
-
Estrogen resistanoe caused by a mutation in the estrogen-receptor gene in a man
-
Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB & Korach KS 1994 Estrogen resistanoe caused by a mutation in the estrogen-receptor gene in a man. New England Journal of Medicine 331 1056-1061.
-
(1994)
New England Journal of Medicine
, vol.331
, pp. 1056-1061
-
-
Smith, E.P.1
Boyd, J.2
Frank, G.R.3
Takahashi, H.4
Cohen, R.M.5
Specker, B.6
Williams, T.C.7
Lubahn, D.B.8
Korach, K.S.9
-
40
-
-
0031962552
-
Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression
-
Sun WH, Pabon C, Alsayed Y, Huang PP, Jandeska S, Uddin S, Platanias LC & Rosen ST 1998 Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression. Blood 91 570-576.
-
(1998)
Blood
, vol.91
, pp. 570-576
-
-
Sun, W.H.1
Pabon, C.2
Alsayed, Y.3
Huang, P.P.4
Jandeska, S.5
Uddin, S.6
Platanias, L.C.7
Rosen, S.T.8
-
42
-
-
0029958796
-
3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts
-
3 enhances the enzymatic activity and expression of the messenger ribonucleic acid for aromatase cytochrome P450 synergistically with dexamethasone depending on the vitamin D receptor level in cultured human osteoblasts. Endocrinology 137 1860-1869.
-
(1996)
Endocrinology
, vol.137
, pp. 1860-1869
-
-
Tanaka, S.1
Haji, M.2
Takayanagi, R.3
Tanaka, S.4
Sugioka, Y.5
Nawata, H.6
-
43
-
-
0034625044
-
Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice
-
Vidal O, Lindberg MK, Hollberg K, Baylink DJ, Andersson G, Lubahn DB, Mohan S, Gustafsson JA & Ohlsson C 2000 Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. PNAS 97 5474-5479.
-
(2000)
PNAS
, vol.97
, pp. 5474-5479
-
-
Vidal, O.1
Lindberg, M.K.2
Hollberg, K.3
Baylink, D.J.4
Andersson, G.5
Lubahn, D.B.6
Mohan, S.7
Gustafsson, J.A.8
Ohlsson, C.9
-
44
-
-
0028919673
-
Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes
-
Zhao Y, Mendelson CR & Simpson ER 1995a Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes. Molecular Endocrinology 9 340-349.
-
(1995)
Molecular Endocrinology
, vol.9
, pp. 340-349
-
-
Zhao, Y.1
Mendelson, C.R.2
Simpson, E.R.3
-
45
-
-
0029002074
-
Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter
-
Zhao Y, Nichols JE, Bulun SE, Mendelson CR & Simpson ER 1995b Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter. Journal of Biological Chemistry 270 16449-16457.
-
(1995)
Journal of Biological Chemistry
, vol.270
, pp. 16449-16457
-
-
Zhao, Y.1
Nichols, J.E.2
Bulun, S.E.3
Mendelson, C.R.4
Simpson, E.R.5
|