Endogenously produced adenosine regulates articular cartilage matrix homeostasis: Enzymatic depletion of adenosine stimulates matrix degradation

Osteoarthritis and Cartilage

Volumn 12, Issue 5, 2004, Pages 349-359

  Tesch, A M ^a   MacDonald, M H ^a   Kollias Baker, C ^b   Benton, H P ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of Florida College of Veterinary Medicine   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenosine; Adenosine deaminase; Cartilage; Degradation

Indexed keywords

4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 5 IODOTUBERCIDIN; 6 N [2 (3,5 DIMETHOXYPHENYL) 2 (2 METHYLPHENYL)ETHYL]ADENOSINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE; ADENOSINE A2 RECEPTOR; ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE DEAMINASE; ADENOSINE KINASE INHIBITOR; ADENOSINE RECEPTOR BLOCKING AGENT; CAFFEINE; CELL SURFACE RECEPTOR; COLLAGENASE 3; GLYCOSAMINOGLYCAN; NITRIC OXIDE; PROSTAGLANDIN E2; STROMELYSIN; THEOPHYLLINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; AUTOCRINE EFFECT; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME RELEASE; EXPERIMENTATION; EXPLANT; EXPOSURE; EXTRACELLULAR SPACE; HOMEOSTASIS; INFLAMMATION; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; RECEPTOR BLOCKING; REGULATORY MECHANISM;

EID: 2342533099     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2004.01.002     Document Type: Article

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