Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

Molecular Biology of the Cell

Volumn 12, Issue 6, 2001, Pages 1583-1594

  Taylor, E M ^a   Moghraby, J S ^a   Lees, J H ^a   Smit, B ^a   Moens, P B ^a   Lehmann, A R ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; DIMER; PROTEIN RAD18; PROTEIN SPR18; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CHROMATIN; CHROMOSOME STRUCTURE; COMPLEX FORMATION; DNA REPAIR; DNA REPLICATION; MEIOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SCHIZOSACCHAROMYCES POMBE;

SCHIZOSACCHAROMYCES POMBE;

EID: 0035167402     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.6.1583     Document Type: Article

References (45)

1. Distribution of the Rad51 recombinase in human and mouse spermatocytes
2. The hMre11/hRad50 protein complex and Nijmegen breakage-syndrome: Linkage of double-strand break repair to the cellular DNA damage response
3. Review: SMCs in the world of chromosome biology: From prokaryotes to higher eukaryotes
4. Characterization of the components of the putative mammalian sister chromatid cohesion complex
5. A physical map of 30,000 human genes
6. Human Rad50 is physically associated with human Mre11: Identification of a conserved multiprotein complex implicated in recombinational DNA repair
7. Localization of RAD50 and MRE11 in spermatocyte nuclei of mouse and rat
8. A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein
9. Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: Linkage to checkpoint control and mammalian meiosis
10. A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
11. A serine kinase regulates intracellular localization of splicing factors in the cell cycle
12. The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis
13. SMC protein complexes and higher-order chromosome dynamics
14. SMC-mediated chromosome mechanics: A conserved scheme from bacteria to vertebrates?
15. Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila barren protein
16. A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro
17. Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
18. Chromosome dynamics: The SMC protein family
19. SMC proteins constitute two subunits of the mammalian recombination complex RC-1
20. The Atr and Atm protein-kinases associate with different sites along meiotically pairing chromosomes
21. The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair
22. Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres
23. Identification of Xenopus SMC protein complexes required for sister chromatid cohesion
24. Coiled coils: New structures and new functions
25. The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins; long, antiparallel coiled coils, folded at a flexible hinge
26. An SMC-like protein is required for efficient homologous recombination in Arabidopsis
27. Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
28. Purification and biochemical characterization of interchromatin granule clusters
29. The dynamics of a pre-mRNA splicing factor in living cells
30. Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors
31. Rad51 immunocytology in rat and mouse spermatocytes and oocytes
32. Expression and nuclear localization of BLM, a chromosome stability protein mutated in Bloom's syndrome, suggest a role in recombination during meiotic prophase
33. The association of ATR protein with mouse meiotic chromosome cores
34. A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix
35. Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance
36. Splitting the chromosome: Cutting the ties that bind sister chromatids
37. Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics
38. Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide
39. Use of damaged plasmid to study DNA repair in x-ray sensitive (xrs) strains of Chinese hamster ovary (CHO) cells
40. Macromolecular domains within the cell nucleus
41. SMC2, a Saccharomyces cerevisiae gene essential for chromosome segregation and condensation, defines a subgroup within the SMC family
42. Structural maintenance of chromosomes (SMC) proteins: Conserved molecular properties for multiple biological functions
43. Fission yeast condensin complex: Essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4
44. Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens
45. Rad18 is required for DNA repair and checkpoint responses in fission yeast