A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein

EMBO Journal

Volumn 19, Issue 7, 2000, Pages 1691-1702

  Fousteri, Maria I ^a   Lehmann, Alan R ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

ATPase; Coiled coils; DNA repair; Fission yeast; SMC proteins

Indexed keywords

ADENOSINE TRIPHOSPHATE; FUNGAL DNA; FUNGAL PROTEIN; MUTANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FUNGAL GENETICS; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SCHIZOSACCHAROMYCES POMBE;

SCHIZOSACCHAROMYCES POMBE;

EID: 0034599577     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.7.1691     Document Type: Article

References (38)

1. Akhmedov, A.T., Frei, C., Tsai-Pflugfelder, M., Kemper, B., Gasser, S.M. and Jessberger, R. (1998) Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structure. J. Biol. Chem., 273, 24088-24094.
2. Ames, G.F.-L., Mimura, C.S., Holbrook, S.R. and Shyamata, V. (1992) Traffic ATPases: a superfamily of transport proteins operating from Escherichia coli to humans. Adv. Enzymol., 65, 1-47.
3. Avery, A.M., Kaur, B., Taylor, J.S., Mello, J.A., Essigmann, J.M. and Doetsch, P.W. (1999) Substrate specificity of ultraviolet DNA endonuclease (UVDE/Uvelp) from Schizosaccharomyces pombe. Nucleic Acids Res., 27, 2256-2264.
4. Blat, Y. and Kleckner, N. (1999) Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric region. Cell, 98, 249-259.
5. Browne, B.L., McClendon, V. and Bedwell, D.M. (1996) Mutations within the first LSGGQ motif of Ste6p cause defects in a-factor transport and mating in Saccharomyces cerevisiae. J. Bacteriol., 178, 1712-1719.
6. Carr, A., MacNeil, S.A., Hayles, J. and Nurse, P. (1989) Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2+ protein structure and function. Mol. Gen. Genet., 218, 41-49.
7. Caspari, T. and Carr, A.M. (1999) DNA structure checkpoint pathways in Schizosaccharomyces pombe. Biochimie, 81, 173-181.
8. Chuang, P., Lieb, J.D. and Meyer, B.J. (1996) Sex-specific assembly of a dosage compensation complex on the nematode X chromosome. Science, 274, 1736-1739.
9. Craven, R.A., Griffiths, D.J.F., Sheldrick, K.S., Randall, R.E., Hagan, I.M. and Carr, A.M. (1998) Vectors for the expression of tagged proteins in Schizosaccharomyces pombe. Gene, 221, 59-68.
10. Gregory, R.J., Rich, D.P., Cheng, S.H., Souza, D.W., Paul, S., Manavalan, P., Anderson, M.P., Welsh, M.J. and Smith, A.E. (1991) Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2. Mol. Cell. Biol., 11, 3886-3893.
11. Harlow, E. and Lane, D. (1988) Antibodies. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
12. Hirano, T. (1998) SMC protein complexes and higher-order chromosome dynamics. Curr. Opin. Cell Biol., 10, 317-322.
13. Hirano, T. (1999) SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates? Genes Dev., 13, 11-19.
14. Hirano, T., Kobayashi, R. and Hirano, M. (1997) Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila barren protein. Cell, 89, 511-521.
15. UGA gene is active in S. cerevisiae. Mol. Gen. Genet., 188, 219-224.
16. Jessberger, R., Riwar, B., Beachtold, H. and Akhmedov, A.T. (1996) SMC proteins constitute two subunits of the mammalian recombination complex RC-1. EMBO J., 15, 4061-4068.
17. Jessberger, R., Frei, C. and Gasser, S.M. (1998) Chromosome dynamics: the SMC protein family. Curr. Opin. Genet. Dev., 8, 254-259.
18. Kerem, B.S. et al. (1990) Identification of mutations in regions corresponding to the two putative nucleotide (ATP)-binding folds of the cystic fibrosis gene. Proc. Natl Acad. Sci. USA, 87, 8447-8451.
19. Kimura, K. and Hirano, T. (1997) ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. Cell, 90, 625-634.
20. Kimura, K., Rybenkov, V.V., Crisona, N.J., Hirano, T. and Cozzarelli, N.R. (1999) 13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell, 98, 239-248.
21. Kunkel, T.A., Roberts, J.D. and Zakour, R.A. (1987) Rapid and efficient site specific mutagenesis without phenotypic selection. Methods Enzymol., 154, 367-368.
22. Lehmann, A.R. (1996) Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe. Mutat. Res., 363, 147-161.
23. Lehmann, A.R., Walicka, M., Griffiths, D.J.F., Murray, J.M., Watts, F.Z., McCready, S. and Carr, A.M. (1995) The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol. Cell. Biol., 15, 7067-7080.
24. Losada, A., Hirano, M. and Hirano, T. (1998) Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev., 12, 1986-1997.
25. Lupas, A., Van Dyke, M. and Stock, J. (1991) Predicting coiled coils from protein sequences. Science, 252, 1162-1164.
26. Maundrell, K. (1993) Thiamine-repressible expression vectors pREP and pRIP for fission yeast. Gene, 123, 127-130.
27. Melby, T.E., Ciampaglio, C.N., Briscoe, G. and Erickson, H.P. (1998) The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge. J. Cell Biol., 142, 1595-1604.
28. Mengiste, T., Revenkova, E., Bechtold, N. and Paszkowski, J. (1999) An SMC-like protein is required for efficient homologous recombination in Arabidopsis. EMBO J., 18, 4505-4512.
29. Michaelis, C., Ciosk, R. and Nasmyth, K. (1997) Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell, 91, 35-45.
30. Muris, D.F.R., Vreeden, K., Carr, A.M., Broughton, B.C., Lehmann, A.R., Lohman, P.H.M. and Pastink, A. (1993) Cloning the RAD51 homologue of Schizosaccharomyces pombe. Nucleic Acids Res., 21, 4586-4591.
31. +, a gene involved in the repair of radiation damage and replication fidelity. J. Cell Sci., 109, 73-81.
32. Murray, J.M., Lindsay, H.D., Munday, C.A. and Carr, A.M. (1997) Role of Schizosaccharomyces pombe RecQ homolog, recombination and checkpoint genes in UV damage tolerance. Mol. Cell. Biol., 17, 6868-6875.
33. Sutani, T., Yuasa, T., Tomonaga, T., Dohmae, N., Takio, K. and Yanagida, M. (1999) Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4. Genes Dev., 13, 2271-2283.
34. Tanaka, T., Cosma, M.P., Wirth, K. and Nasmyth, K. (1999) Identification of cohesin association sites at centromeres and along chromosome arms. Cell, 98, 847-858.
35. Verkade, H.M., Bugg, S.J., Lindsay, H.D., Carr, A.M. and O'Connell, M.J. (1999) Rad18 is required for DNA repair and checkpoint responses in fission yeast. Mol. Biol. Cell, 10, 2905-2918.
36. Yasui, A. and McCready, S.J. (1998) Alternative repair pathways for UV-induced DNA damage. BioEssays, 20, 291-297.
37. Yonemasu, R., McCready, S., Murray, J.M., Osman, F., Takao, M., Yamamoto, K., Lehmann, A.R. and Yasui, A. (1997) Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe. Nucleic Acids Res., 25, 1553-1558.
38. Yoon, J.H., Swiderski, P.M., Kaplan, B.E., Takao, M., Yasui, A., Shen, B. and Pfeifer, G.P. (1999) Processing of UV damage in vitro by FEN-1 proteins as part of an alternative DNA excision repair pathway. Biochemistry, 38, 4809-4817.