Generation and characterization of mutant cell lines defective in γ-secretase processing of notch and amyloid precursor protein

Journal of Biological Chemistry

Volumn 280, Issue 31, 2005, Pages 28564-28571

  Olry, Annie ^a   Chastagner, Patricia ^a   Israël, Alain ^a   Brou, Christel ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELL CULTURE; CELL MEMBRANES; CELLS; COMPLEXATION; CYTOLOGY; ENZYMES;

MEMBRANE PROTEINS; MULTIPROTEIN COMPLEX; NOTCH RECEPTOR; PRECURSOR PROTEINS;

PROTEINS;

AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; MEMBRANE PROTEIN; NICASTRIN; NOTCH RECEPTOR; PEN 2 PROTEIN; PRESENILIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CELL LINE; CLONE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE MUTATION; HUMAN; HUMAN CELL; MAMMAL CELL; MUTAGENESIS; MUTANT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; DNA PRIMERS; ENDOPEPTIDASES; GENETIC VECTORS; HUMANS; KINETICS; MEMBRANE PROTEINS; MUTAGENESIS; POLYMERASE CHAIN REACTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECEPTORS, NOTCH; RECOMBINANT PROTEINS;

MAMMALIA;

EID: 23344431985     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502199200     Document Type: Article

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