Intracellular signaling mechanisms responsive to laser-induced photochemical and thermal stress

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 5695, Issue , 2005, Pages 260-269

  Glickman, Randolph D ^a   Natarajan, Mohan ^a   Rockwell, Benjamin ^b   Denton, Michael ^c   Maswadi, Saher ^a   Kumar, Neeru ^a   Nieves Roldan, Francis ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b AIR FORCE RESEARCH LABORATORY   (United States)

^c Northrup Grumman Info Technology   (United States)

Author keywords

Antioxidants; Laser; NF B; Photo oxidative stress; Retinal pigment epithelium; Transcription factors

Indexed keywords

NF-ΚB; PHOTO-OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM; TRANSCRIPTION FACTORS;

ANTIOXIDANTS; BIOASSAY; LASER APPLICATIONS; PHOTOOXIDATION; PIGMENTS; PROTEINS; THERMAL STRESS;

CELLS;

EID: 23244459014     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.584135     Document Type: Conference Paper

References (59)

1. R.D. Glickman, "Phototoxicity to the retina: Mechanisms of damage," Int. J. Toxicol, 21, pp. 473-490, 2002.
2. W.T. Ham Jr, R.G. Allen, L. Feeney-Burns, M.F. Marmor, L.M. Parver, P.H. Proctor, D.H. Sliney, and M.L. Wolbarsht, "The involvement of the retinal pigment epithelium (RPE)," in Optical Radiation and Visual Health, M. Waxier Ed., pp. 43-67, CRC Press, Boca Raton, FL, 1986.
3. D.T. Organisciak, R.A. Darrow, L. Barsalou, R.M. Darrow, and L.A. Lininger, "Light-induced oxidative damage and apoptosis in the retina," Invest Ophthalmol. Visual. Sci., 38 (ARVO Suppl.), pp. S1028, 1997.
4. C. Reme, J. Reinboth, M. Clausen, and F. Hafezi, "Light damage revisited: converging evidence, diverging views?" Graefes. Arch. Clin. Exp. Ophthalmol., 234, pp. 2-11, 1996.
5. J.E. Roberts, "Ocular phototoxicity," in Dermatotoxicology, F.N. Marzuli Ed., pp. 307-313, Taylor and Francis, Washington, D.C., 1996.
6. S.L. Jacques, "Laser-tissue interactions. Photochemical, photothermal, and photomechanical," Surg. Clin. North Am., 72, pp. 531-558, 1992.
7. W.R. Elliott, H. Zwick, P. Edsall, M. Reddix, and B.E. Stuck, "Oxidative stress in retinal photoreceptors after acute laser lesion: 2,7- dichlorodihydrofluorescein diacetate in the small eye," Invest. Ophthalmol. Visual. Sci., 40(ARVO Suppl), pp. S955, 1999.
8. B.S. Gerstman and R.D. Glickman, "Activated rate processes and a specific biochemical mechanism for explaining delayed laser induced thermal damage to the retina," J. Biomed. Opt., 4, pp. 345-351, 1999.
9. K. Konig, Y. Tadir, P. Patrizio, M.W. Berns, and B.J. Tromberg, "Effects of ultraviolet exposure and near infrared laser tweezers on human spermatozoa," Hum. Reprod., 11, pp. 2162-2164, 1996.
10. C.P. Lin, M.C. Lynch, and I.E. Kochevar, "Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells," Exp. Cell Res., 259, pp. 351-359, 2000.
11. M. Karin, T. Takahashi, P. Kapahi, M. Delhase, Y. Chen, C. Makris, D. Rothwarf, V. Baud, G. Natoli, F. Guido, and N. Li, "Oxidative stress and gene expression: the AP-1 and NF-kappaB connections," Biofactors, 15, pp. 87-89, 2001.
12. P. Herrlich, P. Angel, H.J. Rahmsdorf, U. Mallick, A. Poting, L. Hieber, C. Lucke-Huhle, and M. Schorpp, "The mammalian genetic stress response," Adv. Enzyme Regul., 25, pp. 485-504, 1986.
13. P. Herrlich, K. Bender, A. Knebel, F.D. Bohmer, S. Gross, C. Blattner, H.J. Rahmsdorf, and M. Gottlicher, "Radiation-induced signal transduction. Mechanisms and consequences," C. R. Acad. Sci. III., 322, pp. 121-125, 1999.
14. F.E. Chen and G. Ghosh, "Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views," Oncogene, 18, pp. 6845-6852, 1999.
15. T.D. Gilmore, "The Rel/NF-kappaB signal transduction pathway: introduction," Oncogene, 18, pp. 6842-6844, 1999.
16. M. Karin, "How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex," Oncogene, 18, pp. 6867-6874, 1999.
17. M. Karin, Y. Yamamoto, and Q.M. Wang, "The IKK NF-kappa B system: a treasure trove for drug development," Nat. Rev. Drug Discov., 3, pp. 17-26, Jan. 2004.
18. H.L. Pahl, "Activators and target genes of Rel/NF-kappaB transcription factors," Oncogene, 18, pp. 6853-6866, 1999.
19. A.A. Beg and D. Baltimore, "An essential role for NF-kappaB in preventing TNF-alpha-induced cell death," Science, 274, pp. 782-784, 1996.
20. X. Hu, M. Tang, A.B. Fisher, N. Olashaw, and K.S. Zuckerman, "TNF-alpha-induced growth suppression of CD34+ myeloid leukemic cell lines signals through TNF receptor type I and is associated with NF-kappa B activation," J. Immunol., 163, pp. 3106-3115, 1999.
21. N. Mohan and M.L. Meltz, "Induction of nuclear factor kappa B after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathway," Radiation Research, 140, pp. 97-104, 1994.
22. S.J. Lee, A. Dimtchev, M.F. Lavin, A. Dritschilo, and M. Jung, "A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB," Oncogene, 17, pp. 1821-1826, 1998.
23. U. Raju, G.J. Gumin, and P.J. Tofilon, "NF kappa B activity and target gene expression in the rat brain after one and two exposures to ionizing radiation," Radiat Oncol. Investig., 7, pp. 145-152, 1999.
24. M.M. Simon, Y. Aragane, A. Schwarz, T.A. Luger, and T. Schwarz, "UVB light induces nuclear factor kappa B (NF kappa B) activity independently from chromosomal DNA damage in cell-free cytosolic extracts," J. Invest. Dermatol., 102, pp. 422-427, 1994.
25. M. Los, H. Schenk, K. Hexel, P.A. Baeuerle, W. Droge, and K. Schulze-Osthoff, "IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase," EMBO J., 14, pp. 3731-3740, 1995.
26. G.F. Vile, A. Tanew-Ilitschew, and R.M. Tyrrell, "Activation of NF-kappa B in human skin fibroblasts by the oxidative stress generated by UVA radiation," Photochem. Photobiol, 62, pp. 463-468, 1995.
27. N. Li and M. Karin, "Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms," Proc. Natl. Acad. Sci. U. S. A., 95, pp. 13012-13017, 1998.
28. Y. Devary, C. Rosette, J. DiDonato, and M. Karin, "NF-kB activation by ultraviolet light not dependent on a nuclear signal," Science, 261, pp. 1442-1445, 1993.
29. L. Flohe, R. Brigelius-Flohe, C. Saliou, M.G. Traber, and L. Packer, "Redox regulation of NF-Kappa B," Free Radic. Biol. Med., 22, pp. 1115-1126, 1997.
30. S.W. Ryter and C.J. Gomer, "Nuclear factor kappa B binding activity in mouse L1210 cells following photofrin II-mediated photosensitization," Photochem. Photobiol, 58, pp. 753-756, 1993.
31. S. Legrand-Poels, V. Bours, B. Piret, M. Pflaum, B. Epe, B. Rentier, and J. Piette, "Transcription factor NF-kappa B is activated by photosensitization generating oxidative DNA damages," J. Biol. Chem., 270, pp. 6925-6934, 1995.
32. D.J. Granville, C.M. Carthy, H. Jiang, J.G. Levy, B.M. McManus, J.Y. Matroule, J. Piette, and D.W. Hunt, "Nuclear factor-kappaB activation by the photochemotherapeutic agent verteporfin," Blood, 95, pp. 256-262, 2000.
33. T. Hayashi, Y. Ueno, and T. Okamoto, "Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin," J. Biol. Chem., 268, pp. 11380-11388, 1993.
34. H. Schenk, M. Klein, W. Erdbrugger, W. Droge, and K. Schulze-Osthoff, "Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1," Proc. Natl. Acad. Sci. U. S. A., 91, pp. 1672-1676, 1994.
35. K. Schulze-Osthoff, H. Schenk, and W. Droge, "Effects of thioredoxin on activation of transcription factor NF-kappa B," Methods. Enzymol, 252, pp. 253-264, 1995.
36. M. Barkett and T.D. Gilmore, "Control of apoptosis by Rel/NF-kappaB transcription factors," Oncogene, 18, pp. 6910-6924, 1999.
37. M.P. Mattson, Y. Goodman, H. Luo, W. Fu. and K. Furukawa, "Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese Superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration," J. Neurosci. Res., 49, pp. 681-697, 1997.
38. M. Grilli, M. Pizzi, M. Memo, and P. Spano, "Neuroprotection by aspirin and sodium salicylate through blockade of NF- kappaB activation," Science, 274, pp. 1383-1385, 1996.
39. A. Schneider, A. Martin-Villalba, F. Weih, J. Vogel, T. Wirth, and M. Schwaninger, "NF-kappaB is activated and promotes cell death in focal cerebral ischemia," Nat. Med., 5, pp. 554-559, 1999.
40. R.R. Krishnamoorthy, M.J. Crawford, M.M. Chaturvedi, S.K. Jain, B.B. Aggarwal, M.R. Al-Ubaidi, and N. Agarwal, "Photo-oxidative stress down-modulates the activity of nuclear factor- kappaB via involvement of caspase-1, leading to apoptosis of photoreceptor cells," J. Biol. Chem., 274, pp. 3734-3743, 1999.
41. M.J. Crawford, R.R. Krishnamoorthy, V.L. Rudick, R.J. Collier, M. Kapin, B.B. Aggarwal, M.R. Al-Ubaidi, and N. Agarwal, "Bcl-2 overexpression protects photooxidative stress-induced apoptosis of photoreceptor cells via NF-kappaB preservation," Biochem. Biophys. Res. Commun., 281, pp. 1304-1312, 2001.
42. S. Legrand-Poels, S. Schoonbroodt, J.Y. Matroule, and J. Piette, "Nf-kappa B: an important transcription factor in photobiology," J. Photochem. Photobiol. B, Biol., 45, pp. 1-8, 1998.
43. A.G. Bodnar, M. Ouellette, M. Frolkis, S.E. Holt, C.P. Chiu, G.B. Morin, C.B. Harley, J.W. Shay, S. Lichtsteiner, and W.E. Wright, "Extension of life-span by introduction of telomerase into normal human cells," Science, 279, pp. 349-352, 1998.
44. X.R. Jiang, G. Jimenez, E. Chang, M. Frolkis, B. Kusler, M. Sage, M. Beeche, A.G. Bodnar, G.M. Wahl, T.D. Tlsty, and C.P. Chiu, "Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype," Nat. Genet., 21, pp. 111-114, 1999.
45. R.D. Glickman, "The origin of photo-oxidative stress in the aging eye," Prog. Brain. Res., 131, pp. 699-712, 2001.
46. S. Mohan, N. Mohan, A.J. Valente, and E.A. Sprague, "Regulation of low shear flow-induced HAEC VCAM-1 expression and monocyte adhesion," Am. J. Physiol., 276, pp. C1100-C1107, 1999.
47. K.W. Lam and R.D. Glickman, "Prevention of light-induced free radical production from melanin granules by ascorbic acid," in Oxygen Radicals (International Conference on Oxygen Radicals, Nov. 1991, Kyoto, Japan), K. Yagi Ed., pp. 633-636, Elsevier Science Publishers, Amsterdam, 1992.
48. R.G. Allen and M. Tresini, "Oxidative stress and gene regulation," Free Radic.Biol.Med., 28, pp. 463-499, Feb 1. 2000.
49. R.D. Glickman, R. Sowell, and K.W. Lam, "Kinetic properties of light-dependent ascorbic acid oxidation by melanin," Free Radic. Biol. Med., 15, pp. 453-457, 1993.
50. A.E. Dontsov, R.D. Glickman, and M.A. Ostrovsky, "Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids," Free Radic. Biol. Med., 26, pp. 1436-1446, 1999.
51. C.L. Li, X.Y. Wang, J. Shao, J.S. Zhang, W.G. Feng, Y.B. Wang, and Z.L. Chang, "Heat shock inhibits IL-12 p40 expression through NF-kappa B signalling pathway in murine macrophages," Cytokine, 16, pp. 153-159, Nov 21. 2001.
52. H.R. Wong, M.A. Ryan, I.Y. Menendez, and J.R. Wispe, "Heat shock activates the I-kappaBalpha promoter and increases I-kappaBalpha mRNA expression," Cell Stress Chaperones, 4, pp. 1-7, Mar. 1999.
53. P. Maroni, P. Bendinelli, L. Tiberio, F. Rovetta, R. Piccoletti, and L. Schiaffonati, "In vivo heat-shock response in the brain: signalling pathway and transcription factor activation," Brain Res. Mol. Brain Res., 119, pp. 90-99, Nov 6. 2003.
54. K.H. Lee, Y.H. Hwang, C.T. Lee, Y.W. Ki, S.K. Han, Y.S. Shim, and C.G. Yoo, "The heat-shock-induced suppression of the IkappaB/NF-kappaB cascade is due to inactivation of upstream regulators of IkappaBalpha through insolubilization," Exp. Cell Res., 299, pp. 49-56, Sep 10. 2004.
55. J.C. Epinat and T.D. Gilmore, "Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway," Oncogene, 18, pp. 6896-6909, 1999.
56. T. Wang, X. Zhang, and J.J. Li, "The role of NF-kappaB in the regulation of cell stress responses," Int. Immunopharmacol., 2, pp. 1509-1520, Oct. 2002.
57. M. Hayakawa, H. Miyashita, I. Sakamoto, M. Kitagawa, H. Tanaka, H. Yasuda, M. Karin, and K. Kikugawa, "Evidence that reactive oxygen species do not mediate NF-kappaB activation," EMBO J., 22, pp. 3356-3366, Jul 1. 2003.
58. L. Rambhatla, C.P. Chiu, R.D. Glickman, and C. Rowe-Rendleman, "In vitro differentiation capacity of telomerase immortalized human RPE cells," Invest. Ophthalmol. Visual. Sci., 43, pp. 1622-1630, 2002.
59. P. Yang, B.S. McKay, J.B. Allen, and G.J. Jaffe, "Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells," Invest. Ophthalmol Vis. Sci., 45, pp. 2438-2446, Jul. 2004.