메뉴 건너뛰기




Volumn 175, Issue 2, 2005, Pages 829-838

Orally tolerized T cells can form conjugates with APCs but are defective in immunological synapse formation

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD4 ANTIGEN; INTEGRIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; OVALBUMIN; PROTEIN CDC42; PROTEIN KINASE C THETA; RAC1 PROTEIN; RAP PROTEIN; T LYMPHOCYTE RECEPTOR; VAV PROTEIN;

EID: 23244442070     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.2.829     Document Type: Article
Times cited : (39)

References (69)
  • 1
    • 2942620546 scopus 로고    scopus 로고
    • Therapeutic potential of oral tolerance
    • Mayer, L., and L. Shao. 2004. Therapeutic potential of oral tolerance. Nat. Rev. Immunol. 4: 407-419.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 407-419
    • Mayer, L.1    Shao, L.2
  • 2
    • 0027538442 scopus 로고
    • Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin
    • Melamed, D., and A. Friedman. 1993. Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin. Eur. J. Immunol. 23: 935-942.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 935-942
    • Melamed, D.1    Friedman, A.2
  • 3
    • 0027980924 scopus 로고
    • Induction of clonal anergy by oral administration of staphylococcal enterotoxin B
    • Migita, K., and A. Ochi. 1994. Induction of clonal anergy by oral administration of staphylococcal enterotoxin B. Eur. J. Immunol. 24: 2081-2086.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2081-2086
    • Migita, K.1    Ochi, A.2
  • 4
    • 0030586668 scopus 로고    scopus 로고
    • Direct measurement of anergy of antigen-specific T cells following oral tolerance induction
    • Van Houten, N., and S. F. Blake. 1996. Direct measurement of anergy of antigen-specific T cells following oral tolerance induction. J. Immunol. 157: 1337-1341.
    • (1996) J. Immunol. , vol.157 , pp. 1337-1341
    • Van Houten, N.1    Blake, S.F.2
  • 5
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy, K. J., and F. Powrie. 2001, Regulatory T cells in the control of immune pathology. Nat. Immunol. 2: 816-822.
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 6
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen, Y., V. K. Kuchroo, J. Inobe, D. A. Hafler, and H. L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265: 1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 7
    • 0029031681 scopus 로고
    • Peripheral deletion of antigen-reactive T cells in oral tolerance
    • Published erratum appears in 1995 Nature 377: 257
    • Chen, Y., J. Inobe, R. Marks, P. Gonnella, V. K. Kuchroo, and H. L. Weiner. 1995. Peripheral deletion of antigen-reactive T cells in oral tolerance. [Published erratum appears in 1995 Nature 377: 257.] Nature 376: 177-180.
    • (1995) Nature , vol.376 , pp. 177-180
    • Chen, Y.1    Inobe, J.2    Marks, R.3    Gonnella, P.4    Kuchroo, V.K.5    Weiner, H.L.6
  • 10
    • 0031569452 scopus 로고    scopus 로고
    • γδ lymphocytes regulate the induction and maintenance of oral tolerance
    • Ke, Y., K. Pearce, J. P. Lake, H. K. Ziegler, and J. A. Kapp. 1997. γδ lymphocytes regulate the induction and maintenance of oral tolerance. J. Immunol. 158: 3610-3618.
    • (1997) J. Immunol. , vol.158 , pp. 3610-3618
    • Ke, Y.1    Pearce, K.2    Lake, J.P.3    Ziegler, H.K.4    Kapp, J.A.5
  • 14
    • 0029057590 scopus 로고
    • + T cells anergized by high dose feeding establish oral tolerance to antibody responses when transferred in SCID and nude mice
    • + T cells anergized by high dose feeding establish oral tolerance to antibody responses when transferred in SCID and nude mice. J. Immunol. 154: 6238-6245.
    • (1995) J. Immunol. , vol.154 , pp. 6238-6245
    • Hirahara, K.1    Hisatsune, T.2    Nishijima, K.3    Kato, H.4    Shiho, O.5    Kaminogawa, S.6
  • 15
    • 0032533469 scopus 로고    scopus 로고
    • Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo
    • Dubois, P. M., M. Pihlgren, M. Tomkowiak, M. Van Mechelen, and J. Marvel. 1998. Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo. J. Immunol. 161: 5260-5267.
    • (1998) J. Immunol. , vol.161 , pp. 5260-5267
    • Dubois, P.M.1    Pihlgren, M.2    Tomkowiak, M.3    Van Mechelen, M.4    Marvel, J.5
  • 17
    • 0034654311 scopus 로고    scopus 로고
    • A population of in vivo anergized T cells with a lower activation threshold for the induction of CD25 exhibit differential requirements in mobilization of intracellular calcium and mitogen-activated protein kinase activation
    • Utting, O., S. J. Teh, and H. S. Teh. 2000. A population of in vivo anergized T cells with a lower activation threshold for the induction of CD25 exhibit differential requirements in mobilization of intracellular calcium and mitogen-activated protein kinase activation. J. Immunol. 164: 2881-2889.
    • (2000) J. Immunol. , vol.164 , pp. 2881-2889
    • Utting, O.1    Teh, S.J.2    Teh, H.S.3
  • 19
    • 0032403549 scopus 로고    scopus 로고
    • + T cells have defective expression and function of the activating protein-1 transcription factor
    • + T cells have defective expression and function of the activating protein-1 transcription factor. J. Immunol. 161: 5930-5936.
    • (1998) J. Immunol. , vol.161 , pp. 5930-5936
    • Sundstedt, A.1    Dohlsten, M.2
  • 21
    • 0036839234 scopus 로고    scopus 로고
    • T cell hyporesponsiveness induced by oral administration of ovalbumin is associated with impaired NFAT nuclear translocation and p27kip1 degradation
    • Asai, K., S. Hachimura, M. Kimura, T. Toraya, M. Yamashita, T. Nakayama, and S. Kaminogawa. 2002. T cell hyporesponsiveness induced by oral administration of ovalbumin is associated with impaired NFAT nuclear translocation and p27kip1 degradation. J. Immunol. 169: 4723-4731.
    • (2002) J. Immunol. , vol.169 , pp. 4723-4731
    • Asai, K.1    Hachimura, S.2    Kimura, M.3    Toraya, T.4    Yamashita, M.5    Nakayama, T.6    Kaminogawa, S.7
  • 22
    • 0041845320 scopus 로고    scopus 로고
    • Proteome analysis reveals caspase activation in hyporesponsive CD4 T lymphocytes induced in vivo by the oral administration of antigen
    • Kaji, T., S. Hachimura, W. Ise, and S. Kaminogawa. 2003. Proteome analysis reveals caspase activation in hyporesponsive CD4 T lymphocytes induced in vivo by the oral administration of antigen. J. Biol. Chem. 278: 27836-27843.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27836-27843
    • Kaji, T.1    Hachimura, S.2    Ise, W.3    Kaminogawa, S.4
  • 23
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • Dustin, M. L., and J. A. Cooper. 2000. The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nat. Immunol. 1: 23-29.
    • (2000) Nat. Immunol. , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 24
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C. R., B. A. Freiberg, H. Kupfer, N. Sciaky, and A. Kupfer, 1998. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395: 82-86.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 26
    • 0032545218 scopus 로고    scopus 로고
    • A receptor/cytoskeletal movement triggered by costimulation during T cell activation
    • Wulfing, C., and M. M. Davis. 1998. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science 282: 2266-2269.
    • (1998) Science , vol.282 , pp. 2266-2269
    • Wulfing, C.1    Davis, M.M.2
  • 27
    • 0033613826 scopus 로고    scopus 로고
    • T lymphocyte costimulation mediated by reorganization of membrane microdomains
    • Viola, A., S. Schroeder, Y. Sakakibara, and A. Lanzavecchia. 1999. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science 283: 680-682.
    • (1999) Science , vol.283 , pp. 680-682
    • Viola, A.1    Schroeder, S.2    Sakakibara, Y.3    Lanzavecchia, A.4
  • 29
    • 0041695164 scopus 로고    scopus 로고
    • Continuous T cell receptor signaling required for synapse maintenance and full effector potential
    • Huppa, J. B., M. Gleimer, C. Sumen, and M. M. Davis. 2003. Continuous T cell receptor signaling required for synapse maintenance and full effector potential. Nat. Immunol. 4: 749-755.
    • (2003) Nat. Immunol. , vol.4 , pp. 749-755
    • Huppa, J.B.1    Gleimer, M.2    Sumen, C.3    Davis, M.M.4
  • 30
    • 0035654908 scopus 로고    scopus 로고
    • Distinct patterns of membrane microdomain partitioning in Th1 and Th2 cells
    • Balamuth, F., D. Leitenberg, J. Unternaehrer, I. Mellman, and K. Bottomly. 2001. Distinct patterns of membrane microdomain partitioning in Th1 and Th2 cells. Immunity 15: 729-738.
    • (2001) Immunity , vol.15 , pp. 729-738
    • Balamuth, F.1    Leitenberg, D.2    Unternaehrer, J.3    Mellman, I.4    Bottomly, K.5
  • 32
    • 2442651482 scopus 로고    scopus 로고
    • T cell killing does not require the formation of a stable mature immunological synapse
    • Published erratum appears in 2004 Nat. Immunol. 5: 658
    • Purbhoo, M. A., D. J. Irvine, J. B. Huppa, and M. M. Davis. 2004. T cell killing does not require the formation of a stable mature immunological synapse. [Published erratum appears in 2004 Nat. Immunol. 5: 658.] Nat. Immunol. 5: 524-530.
    • (2004) Nat. Immunol. , vol.5 , pp. 524-530
    • Purbhoo, M.A.1    Irvine, D.J.2    Huppa, J.B.3    Davis, M.M.4
  • 33
    • 0037351084 scopus 로고    scopus 로고
    • Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse
    • Ardouin, L., M. Bracke, A. Mathiot, S. N. Pagakis, T. Norton, N. Hogg, and V. L. Tybulewicz. 2003. Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse. Eur. J. Immunol. 33: 790-797.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 790-797
    • Ardouin, L.1    Bracke, M.2    Mathiot, A.3    Pagakis, S.N.4    Norton, T.5    Hogg, N.6    Tybulewicz, V.L.7
  • 34
    • 0036225013 scopus 로고    scopus 로고
    • Imaging synapse formation during thymocyte selection: Inability of CD3ζ to form a stable central accumulation during negative selection
    • Richte, L. I., P. J. Ebert, L. C. Wu, M. F. Krummel, J. J. Owen, and M. M. Davis. 2002. Imaging synapse formation during thymocyte selection: inability of CD3ζ to form a stable central accumulation during negative selection. Immunity 16: 595-606.
    • (2002) Immunity , vol.16 , pp. 595-606
    • Richte, L.I.1    Ebert, P.J.2    Wu, L.C.3    Krummel, M.F.4    Owen, J.J.5    Davis, M.M.6
  • 38
    • 0032740946 scopus 로고    scopus 로고
    • Regulation of integrin function by T cell activation: Points of convergence and divergence
    • Zell, T., W. J. Kivens, S. A. Kellermann, and Y. Shimizu. 1999. Regulation of integrin function by T cell activation: points of convergence and divergence. Immunol. Res. 20: 127-145.
    • (1999) Immunol. Res. , vol.20 , pp. 127-145
    • Zell, T.1    Kivens, W.J.2    Kellermann, S.A.3    Shimizu, Y.4
  • 41
    • 0036146452 scopus 로고    scopus 로고
    • Rap1 functions as a key regulator of T cell and antigen-presenting cell interactions and modulates T cell responses
    • Katagiri, K., M. Hattori, N. Minato, and T. Kinashi. 2002. Rap1 functions as a key regulator of T cell and antigen-presenting cell interactions and modulates T cell responses. Mol. Cell Biol. 22: 1001-1015.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 1001-1015
    • Katagiri, K.1    Hattori, M.2    Minato, N.3    Kinashi, T.4
  • 42
    • 0036009116 scopus 로고    scopus 로고
    • Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
    • Sebzda, E., M. Bracke, T. Tugal, N. Hogg, and D. A. Cantrell. 2002. Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat. Immunol. 3: 251-258.
    • (2002) Nat. Immunol. , vol.3 , pp. 251-258
    • Sebzda, E.1    Bracke, M.2    Tugal, T.3    Hogg, N.4    Cantrell, D.A.5
  • 43
    • 0031014969 scopus 로고    scopus 로고
    • 2+-mediated activation of Rap1 in human platelets
    • 2+-mediated activation of Rap1 in human platelets. EMBO J. 16: 252-259.
    • (1997) EMBO J. , vol.16 , pp. 252-259
    • Franke, B.1    Akkerman, J.W.2    Bos, J.L.3
  • 44
    • 0346244099 scopus 로고    scopus 로고
    • T cell-antigen recognition and the immunological synapse
    • Huppa, J. B., and M. M. Davis. 2003. T cell-antigen recognition and the immunological synapse. Nat. Rev. Immunol. 3: 973-983.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 973-983
    • Huppa, J.B.1    Davis, M.M.2
  • 46
    • 0032101348 scopus 로고    scopus 로고
    • Membrane compartmentation is required for efficient T cell activation
    • Xavier, R., T. Brennan, Q. Li, C. McCormack, and B. Seed. 1998. Membrane compartmentation is required for efficient T cell activation. Immunity 8: 723-732.
    • (1998) Immunity , vol.8 , pp. 723-732
    • Xavier, R.1    Brennan, T.2    Li, Q.3    McCormack, C.4    Seed, B.5
  • 47
    • 0029082412 scopus 로고
    • Separation of caveolae from associated microdomains of GPI-anchored proteins
    • Schnitzer, J. E., D. P. McIntosh, A. M. Dvorak, J. Liu, and P. Oh. 1995. Separation of caveolae from associated microdomains of GPI-anchored proteins. Science 269: 1435-1439.
    • (1995) Science , vol.269 , pp. 1435-1439
    • Schnitzer, J.E.1    McIntosh, D.P.2    Dvorak, A.M.3    Liu, J.4    Oh, P.5
  • 49
    • 0036631548 scopus 로고    scopus 로고
    • VAV proteins as signal integrators for multi-subunit immune-recognition receptors
    • Turner, M., and D. D. Billadeau. 2002. VAV proteins as signal integrators for multi-subunit immune-recognition receptors. Nat. Rev. Immunol. 2: 476-486.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 476-486
    • Turner, M.1    Billadeau, D.D.2
  • 50
    • 0035851918 scopus 로고    scopus 로고
    • Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells
    • Villalba, M., K. Bi, F. Rodriguez, Y. Tanaka, S. Schoenberger, and A. Altman. 2001. Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells. J. Cell Biol. 155: 331-338.
    • (2001) J. Cell Biol. , vol.155 , pp. 331-338
    • Villalba, M.1    Bi, K.2    Rodriguez, F.3    Tanaka, Y.4    Schoenberger, S.5    Altman, A.6
  • 51
    • 0034730182 scopus 로고    scopus 로고
    • The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface
    • Wulfing, C., A. Bauch, G. R. Crabtree, and M. M. Davis. 2000. The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface. Proc. Natl. Acad. Sci. USA 97: 10150-5.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 10150-10155
    • Wulfing, C.1    Bauch, A.2    Crabtree, G.R.3    Davis, M.M.4
  • 52
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser, E., T. Leung, H. Salihuddin, Z. S. Zhao, and L. Lim. 1994. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367: 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 53
    • 0035284902 scopus 로고    scopus 로고
    • Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice
    • Garcia, G. G., and R. A. Miller. 2001. Single-cell analyses reveal two defects in peptide-specific activation of naive T cells from aged mice. J. Immunol. 166: 3151-3157.
    • (2001) J. Immunol. , vol.166 , pp. 3151-3157
    • Garcia, G.G.1    Miller, R.A.2
  • 56
    • 0036669692 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation
    • Dupre, L., A. Aiuti, S. Trifari, S. Martino, P. Saracco, C. Bordignon, and M. G. Roncarolo. 2002. Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. Immunity 17: 157-166.
    • (2002) Immunity , vol.17 , pp. 157-166
    • Dupre, L.1    Aiuti, A.2    Trifari, S.3    Martino, S.4    Saracco, P.5    Bordignon, C.6    Roncarolo, M.G.7
  • 57
    • 0036499010 scopus 로고    scopus 로고
    • Cbl and Cbl-b in T cell regulation
    • Liu, Y. C., and H. Gu. 2002. Cbl and Cbl-b in T cell regulation. Trends Immunol. 23: 140-143.
    • (2002) Trends Immunol. , vol.23 , pp. 140-143
    • Liu, Y.C.1    Gu, H.2
  • 58
    • 2542501657 scopus 로고    scopus 로고
    • Ubiquitin ligases and the immune response
    • Liu, Y. C. 2004. Ubiquitin ligases and the immune response. Anna. Rev. Immunol. 22: 81-127.
    • (2004) Anna. Rev. Immunol. , vol.22 , pp. 81-127
    • Liu, Y.C.1
  • 61
    • 1642482866 scopus 로고    scopus 로고
    • Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-γ1
    • Katagiri, K., M. Shimonaka, and T. Kinashi. 2004. Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-γ1. J. Biol. Chem. 279: 11875-11881.
    • (2004) J. Biol. Chem. , vol.279 , pp. 11875-11881
    • Katagiri, K.1    Shimonaka, M.2    Kinashi, T.3
  • 62
    • 0033789882 scopus 로고    scopus 로고
    • Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection
    • Amsen, D., A. Kruisbeek, J. L. Bos, and K. Reedquist. 2000. Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection. Eur. J. Immunol. 30: 2832-2841.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2832-2841
    • Amsen, D.1    Kruisbeek, A.2    Bos, J.L.3    Reedquist, K.4
  • 63
    • 0030812812 scopus 로고    scopus 로고
    • Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap1
    • Boussiotis, V. A., G. J. Freeman, A. Berezovskaya, D. L. Barber, and L. M. Nadler. 1997. Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science 278: 124-128.
    • (1997) Science , vol.278 , pp. 124-128
    • Boussiotis, V.A.1    Freeman, G.J.2    Berezovskaya, A.3    Barber, D.L.4    Nadler, L.M.5
  • 64
    • 0141591492 scopus 로고    scopus 로고
    • Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice
    • Ishida, D., H. Yang, K. Masuda, K. Uesugi, H. Kawamoto, M. Hattori, and N. Minato. 2003. Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice. Proc. Natl. Acad. Sci. USA 100: 10919-10924.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10919-10924
    • Ishida, D.1    Yang, H.2    Masuda, K.3    Uesugi, K.4    Kawamoto, H.5    Hattori, M.6    Minato, N.7
  • 65
    • 0034879978 scopus 로고    scopus 로고
    • Interleukin-10-secreting Peyer's patch cells are responsible for active suppression in low-dose oral tolerance
    • Tsuji, N. M., K. Mizumachi, and J. Kurisaki. 2001. Interleukin-10- secreting Peyer's patch cells are responsible for active suppression in low-dose oral tolerance. Immunology 103: 458-464.
    • (2001) Immunology , vol.103 , pp. 458-464
    • Tsuji, N.M.1    Mizumachi, K.2    Kurisaki, J.3
  • 67
    • 0035399985 scopus 로고    scopus 로고
    • + T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • + T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167: 188-195.
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.1    Khoruts, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.