Symmetrical derivatives with nitrogenated functions as cytotoxic agents and apoptosis inducers

Letters in Drug Design and Discovery

Volumn 2, Issue 5, 2005, Pages 341-354

  Sanmartín, Carmen ^a   Ardaiz, Elena ^a   Cordeu, Lucía ^b   Cubedo, Elena ^b   García Foncillas, Jesús ^b   Font, María ^a   Palop, Juan Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Apoptosis; Caspase 3; Cytotoxics; Symmetrical compounds

Indexed keywords

1,4 BIS[3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)BENZOYL]PIPERAZINE; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOTOXIC AGENT; N,N' BUTANE 1,4 DIYLBIS[3 [3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)PHENYL]ACRYLAMIDE]; N,N' BUTANE 1,4 DIYLBIS[3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)BENZAMIDE]; N,N' CYCLOHEXANE 1,4 DIYLBIS[3 (4 HYDROXY 3 METHOXYPHENYL)ACRYLAMIDE]; N,N' CYCLOHEXANE 1,4 DIYLBIS[3 [3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)PHENYL] ACRYLAMIDE]; N,N' CYCLOHEXANE 1,4 DIYLBIS[3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)BENZAMIDE]; N,N' DI(4 METHOXYBENZYL)BUTANE 1,4 DIAMINE; N,N' DI[3 METHOXY 4 (4 METHYLPHENYLSULFONYLOXY)BENZYL]CYCLOHEXANE 1,4 DIAMINE; N,N' PROPANE 1,3 DIYLBIS[4 (4 METHYLPHENYLSULFONYLOXY) 3 METHOXYBENZAMIDE]; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BLADDER CANCER; BREAST CANCER; CANCER CELL CULTURE; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 23244438693     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570180054405794     Document Type: Article

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