Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

Journal of Medicinal Chemistry

Volumn 46, Issue 14, 2003, Pages 3109-3115

  Antonini, Ippolito ^a   Polucci, Paolo ^a   Magnano, Amelia ^a   Gatto, Barbara ^b   Palumbo, Manlio ^b   Menta, Ernesto ^c   Pescalli, Nicoletta ^c   Martelli, Sante ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c Novuspharma SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,7 BIS[1 [[2 (DIMETHYLAMINO)ETHYL]AMINO] 9 OXO 9,10 DIHYDROACRIDINE 4 CARBONYL] 4 METHYL 1,4,7 TRIAZAHEPTANE; 1,7 BIS[4 [N [2 (DIMETHYLAMINO)ETHYL]CARBAMOYL] 9 OXO 9,10 DIHYDROACRIDIN 1 YL] 4 METHYL 1,4,7 TRIAZAHEPTANE; ANTINEOPLASTIC AGENT; BIS(ACRIDINE 4 CARBOXAMIDE); UNCLASSIFIED DRUG;

ARTICLE; CHROMATOPHORE; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG ACTIVITY; DRUG DESIGN; DRUG DNA INTERACTION; DRUG SYNTHESIS; FLUOROMETRY; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ACRIDINES; ANTINEOPLASTIC AGENTS; CELL DIVISION; DNA; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROPHORESIS, AGAR GEL; FLUOROMETRY; HUMANS; INTERCALATING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037784000     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030820x     Document Type: Article

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