Effects of 1, 6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a reactive oxygen species and apoptosis inducing agent, on human leukemia cells in vitro and in vivo

Toxicology and Applied Pharmacology

Volumn 202, Issue 1, 2005, Pages 1-12

  Chang, Y F ^a   Chi, C W ^a,b   Chern, Y T ^c   Wang, J J ^d  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d NATIONAL TAIPEI UNIVERSITY OF NURSING AND HEALTH SCIENCES   (Taiwan)

Author keywords

Annexin V; Apoptosis; Diamantane; HL 60; Molt 3; ROS; SOD

Indexed keywords

1,6 BIS[4 (4 AMINO 3 HYDROXYPHENOXY)PHENYL]DIAMANTANE; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ARSENIC TRIOXIDE; CASPASE 3; DNA; HYDROGEN PEROXIDE; LIPOCORTIN 5; MESSENGER RNA; OXYGEN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL MEMBRANE POTENTIAL; CELL STRAIN HL 60; CONTROLLED STUDY; DIPLOIDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO CULTURE; LEUKEMIA; LEUKEMIA CELL LINE; LYMPHATIC LEUKEMIA; MITOCHONDRIAL MEMBRANE; PROTEIN BINDING; SCID MOUSE; TUMOR GROWTH; TUMOR XENOGRAFT;

ADAMANTANE; ANIMALS; ANNEXIN A5; APOPTOSIS; ARSENICALS; CASPASE 3; CASPASES; CELL CYCLE; CELL DIVISION; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; MICE; MICE, SCID; OXIDES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 10044239071     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.06.013     Document Type: Article

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