Anatomic substrates for cardiac conduction

Heart Rhythm

Volumn 2, Issue 8, 2005, Pages 875-886

  Moorman, Antoon F M ^a   Christoffels, Vincent M ^a   Anderson, Robert H ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Atrioventricular node; Cardiac conduction system; His bundle; Purkinje fibers; Sinus node

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 6;

ARRHYTHMOGENESIS; ATRIOVENTRICULAR CONDUCTION; CELL SPECIFICITY; EMBRYO PATTERN FORMATION; HEART ATRIOVENTRICULAR NODE; HEART ATRIUM ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART CONDUCTION; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION SYSTEM; HEART PREEXCITATION; HEART VENTRICLE ARRHYTHMIA; HIS BUNDLE; HUMAN; NONHUMAN; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SINUS NODE; STANDARD; SUPRAVENTRICULAR TACHYCARDIA; WOLFF PARKINSON WHITE SYNDROME;

EID: 22744431888     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2005.04.025     Document Type: Article

References (98)

1. A.F.M. Moorman V.M. Christoffels Cardiac chamber formation: Development, genes and evolution Physiol Rev 83 2003 1223-1267
2. L. Aschoff Referat uber die Herzstorungen in ihren Beziehungen zu den Spezifischen Muskelsystem des Herzens Verh Dtsch Pathol Ges 14 1910 3-35
3. J.G. Mönckeberg Beitrage zur normalen und pathologischen Anatomie des Herzens Verh Dtsch Pathol Ges 14 1910 64-71
4. A. Keith M. Flack The form and nature of the muscular connections between the primary divisions of the vertebrate heart J Anat Physiol 41 1907 172-189
5. A. Benninghoff Über die Beziehungen des Reizleitungssystems und der papillarmuskeln zu den Konturfasern des Herzschlauches Verh Anat Gesellsch 57 1923 185-208
6. H.F. Stannius Zwei Reihen physiologischer Versuche Arch Anat Physiol Med 1852 85-100
7. W. His Jr Die Tätigkeit des embryonalen Herzens und deren Bedeutung für die Lehre von Herzbewegung beim Erwachsenen Arbeit aus der Medizin Klinik zu Leipzig 14 1893
8. S. Tawara Das Reizleitungssystem des Säugetierherzens 1906
9. C. Thorel Vorläufige Mitteulungen über eine besondere Muskelverbindung zwischen der Cava superior und dem Hisschen bündel Munch Med Woch 56 1909 2159-2161
10. S. Tawara The conduction system of the mammalian heart. An anatomico-histological study of the atrioventricular bundle and the Purkinje fibers 2000 Imperial College Press London
11. A.F.S. Kent The structure of the cardiac tissues at the auricular-ventricular junction J Physiol 47 1913 xvii-xviii
12. A.C. Wenink Congenitally complete heart block with an interrupted Monckeberg sling Eur J Cardiol 9 1979 89-99
13. R.H. Anderson M.J. Davies A.E. Becker Atrio-ventricular ring specialized tissue in the normal heart Eur J Cardiol 2 1974 219-230
14. R.H. Anderson A.E. Becker R. Arnold J.L. Wilkinson The conducting tissues in congenitally corrected transposition Circulation 50 1974 911-923
15. V. Uher Zur pathologie des reizleitungssystem bei kongenitalen herzanomalien Frankf Z Pathol 49 1936 347-354
16. S. Milo S.Y. Ho F.J. Macartney J.L. Wilkinson A.E. Becker A.C. Wenink et al. Straddling and overriding atrioventricular valves: Morphology and classification Am J Cardiol 44 1979 1122-1134
17. R.H. Anderson S.Y. Ho P.C. Gillette A.E. Becker Mahaim, Kent and abnormal atrioventricular conduction Cardiovasc Res 31 1996 480-491
18. M.J. Janse R.H. Anderson Specialized internodal atrial pathways: Fact or fiction? Eur J Cardiol 2 1974 117-136
19. J.M. Kalman J.E. Olgin M.R. Karch M. Hamdan R.J. Lee M.D. Lesh Cristal tachycardias: Origin of right atrial tachycardias from the crista terminalis identified by intracardiac echocardiography J Am Coll Cardiol 31 1998 451-459
20. M.R.M. Jongbloed M.J. Schalij R.E. Poelmann N.A. Blom M.L. Fekkes Z. Wang et al. Embryonic conduction tissue: A spatial correlation with adult arrhythmogenic areas J Cardiovasc Electrophysiol 15 2004 349-355
21. N.A. Blom A.C. Gittenberger-de Groot M.C. deRuiter R.E. Poelmann M.M. Mentink J. Ottenkamp Development of the cardiac conduction tissue in human embryos using HNK-1 antigen expression: Possible relevance for understanding of abnormal atrial automaticity Circulation 99 1999 800-806
22. M. Haissaguerre P. Jais D.C. Shah S. Garrigue A. Takahashi T. Lavergne et al. Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci Circulation 101 2000 1409-1417
23. A. Perez-Lugones J.T. McMahon N.B. Ratliff W.I. Saliba R.A. Schweikert N.F. Marrouche Evidence of specialized conduction cells in human pulmonary veins of patients with atrial fibrillation J Cardiovasc Electrophysiol 14 2003 803-809
24. M.J. Davies R.H. Anderson A.E. Becker The conduction system of the heart 2003 Butterworths London 1-337
25. G. Schram M. Pourrier P. Melnyk S. Nattel Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function Circ Res 90 2002 939-950
26. A.F.M. Moorman Cardiac anatomy a help or a hindrance in understanding cardiac embryologie In: R.H. Anderson A.F.M. Moorman J.J. Piek A.C. van der Wal (eds.), 35 years Cardiovascular pathology in Amsterdam 1 edn 2003 Academic Medical Center Amsterdam 91-99
27. G.H. Paff R.J. Boucek T.C. Harrell Observations on the development of the electrocardiogram Anat Rec 160 1968 575-582
28. W. Seidl M. Schulze G. Steding D. Kluth A few remarks on the physiology of the chick embryo heart (Gallus gallus) Folia Morphol 29 1981 237-242
29. A.F.M. Moorman V.M. Christoffels Development of the cardiac conduction system: A matter of chamber development Novartis Found Symp 250 2003 25-34
30. D. Gros J.P. Mocquard C.E. Challice J. Schrével Formation and growth of gap junctions in mouse myocardium during ontogenesis J Cell Sci 30 1978 45-61
31. B. Delorme E. Dahl T. Jarry-Guichard J.P. Briand K. Willecke D. Gros et al. Expression pattern of connexin gene products at the early developmental stages of the mouse cardiovascular system Circ Res 81 1997 423-437
32. M.J.A. van Kempen C. Fromaget D. Gros A.F.M. Moorman W.H. Lamers Spatial distribution of connexin-43, the major cardiac gap junction protein, in the developing and adult rat heart Circ Res 68 1991 1638-1651
33. A.F.M. Moorman F. de Jong M.M.F.J. Denyn W.H. Lamers Development of the cardiac conduction system Circ Res 82 1998 629-644
34. P.A. de Vries J.B. Saunders C.M. de Development of the ventricles and spiral outflow tract in the human heart Contrib Embryol 37 1962 87-114
35. A.F.M. Moorman W.H. Lamers Molecular anatomy of the developing heart Trends Cardiovasc Med 4 1994 257-264
36. R. Abu-Issa K. Waldo M.L. Kirby Heart fields: One, two or more? Dev Biol 272 2004 281-285
37. G.H. Paff R.J. Boucek H.S. Klopfenstein Experimental heart block in the chick embryo Anat Rec 149 1964 217-224
38. R.P. Harvey Patterning the vertebrate heart Nat Rev Genet 3 2002 544-556
39. T. Brand Heart development: Molecular insights into cardiac specification and early morphogenesis Dev Biol 258 2003 1-19
40. V.E. Papaioannou L.M. Silver The T-box gene family Bioessays 20 1998 9-19
41. N. Rosenthal J. Xavier-Neto From the bottom of the heart: anteroposterior decisions in cardiac muscle differentiation Curr Opin Cell Biol 12 2000 742-746
42. B.G. Bruneau M. Logan N. Davis T. Levi C.J. Tabin J.G. Seidman et al. Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome Dev Biol 211 1999 100-108
43. C.M. Liberatore R.D. Searcy-Schrick K.E. Yutzey Ventricular expression of Tbx5 inhibits normal heart chamber development Dev Biol 223 2000 169-180
44. C.T. Basson D.R. Bachinsky R.C. Lin T. Levi J.A. Elkins J. Soults et al. Mutations in human TBX5 (corrected) cause limb and cardiac malformation in Holt-Oram syndrome Nat Genet 15 1997 30-35
45. Q.Y. Li R.A. Newbury-Ecob J.A. Terrett D.I. Wilson A.R. Curtis C.H. Yi et al. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family Nat Genet 15 1997 21-29
46. B.G. Bruneau G. Nemer J.P. Schmitt F. Charron L. Robitaille S. Caron et al. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease Cell 106 2001 709-721
47. Y. Hiroi S. Kudoh K. Monzen Y. Ikeda Y. Yazaki R. Nagai et al. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation Nat Genet 28 2001 276-280
48. P.E.M.H. Habets A.F.M. Moorman D.E.W. Clout M.A. van Roon M. Lingbeek M. Lohuizen Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: Implications for cardiac chamber formation Genes Dev 16 2002 1234-1246
49. M.J.A. van Kempen J.L.M. Vermeulen A.F.M. Moorman D.B. Gros D.L. Paul W.H. Lamers Developmental changes of connexin40 and connexin43 mRNA-distribution patterns in the rat heart Cardiovasc Res 32 1996 886-900
50. V.M. Christoffels P.E.M.H. Habets D. Franco M. Campione F. de Jong W.H. Lamers et al. Chamber formation and morphogenesis in the developing mammalian heart Dev Biol 223 2000 266-278
51. V.M. Christoffels W.M.H. Hoogaars A. Tessari D.E.W. Clout A.F.M. Moorman M. Campione T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers Dev Dyn 229 2004 763-770
52. W.M.H. Hoogaars A. Tessari A.F.M. Moorman P.A.J. de Boer J. Hagoort A.T. Soufan et al. The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart Cardiovasc Res 62 2004 489-499
53. S. Carreira T.J. Dexter U. Yavuzer D.J. Easty C.R. Goding Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter Mol Cell Biol 18 1998 5099-5108
54. ARF) and is amplified in a subset of human breast cancers Nat Genet 26 2000 291-299
55. Ml. He L. Wen C.E. Campbell J.Y. Wu Y. Rao Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome Proc Natl Acad Sci U S A 96 1999 10212-10217
56. C. Paxton H. Zhao Y. Chin K. Langner J. Reecy Murine Tbx2 contains domains that activate and repress gene transcription Gene 283 2002 117-124
57. R.J. Boucek W.P. Murphy G.H. Paff Electrical and mechanical properties of chick embryo heart chambers Circ Res 7 1959 787-793
58. F. de Jong T. Opthof A.A.M. Wilde M.J. Janse R. Charles W.H. Lamers et al. Persisting zones of slow impulse conduction in developing chicken hearts Circ Res 71 1992 240-250
59. L.M. Eisenberg R.R. Markwald Molecular regulation of atrioventricular valvuloseptal morphogenesis Circ Res 77 1995 1-6
60. F.J. de Lange A.F.M. Moorman R.H. Anderson J. Manner A.T. Soufan C. de Gier-de Vries et al. Lineage and morphogenetic analysis of the cardiac valves Circ Res 95 2004 645-654
61. A.C.G. Wenink Development of the human cardiac conduction system J Anat 121 1976 617-631
62. C.L. Cai X. Liang Y. Shi P.H. Chu S.L. Pfaff J. Chen et al. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart Dev Cell 5 2003 877-889
63. S.R. Coppen E. Dupont S. Rothery N.J. Severs Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart Circ Res 82 1998 232-243
64. S.R. Coppen N.J. Severs R.G. Gourdie Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart Dev Genet 24 1999 82-90
65. S.R. Coppen I. Kodama M.R. Boyett H. Dobrzynski Y. Takagishi H. Honjo et al. Connexin45, a major connexin of the rabbit sinoatrial node, is co-expressed with connexin43 in a restricted zone at the nodal-crista terminalis border J Histochem Cytochem 47 1999 907-918
66. S. Alcolea M. Theveniau-Ruissy T. Jarry-Guichard I. Marics E. Tzouanacou J.P. Chauvin et al. Downregulation of connexin45 gene products during mouse heart development Circ Res 84 1999 1365-1379
67. A.T. Soufan M.J.B. van den Hoff J.M. Ruijter P.A.J. de Boer J. Hagoort S. Webb et al. Reconstruction of the patterns of gene expression in the developing mouse heart reveals an architectural arrangement that facilitates the understanding of atrial malformations and arrhythmias Circ Res 95 2004 1207-1215
68. J. Sissman Cell multiplication rates during development of the primitive cardiac tube in the chick embryo Nature 210 1966 504-507
69. R.P. Thompson T. Kanai P.G. Germroth R.G. Gourdie P.C. Thomas P.J.R. Barton et al. Organization and function of early specialized myocardium In: E.B. Clark R.R. Markwald A. Takao (eds.), Developmental mechanisms of heart disease 1995 Futura Publishing Co, Inc Armonk, NY 269-279
70. S. Rentschler D.M. Vaidya H. Tamaddon K. Degenhardt D. Sassoon G.E. Morley et al. Visualization and functional characterization of the developing murine cardiac conduction system Development 128 2001 1785-1792
71. Y.S. Ko H.I. Yeh Y.L. Ko Y.C. Hsu C.F. Chen S. Wu et al. Three-dimensional reconstruction of the rabbit atrioventricular conduction axis by combining histological, desmin, and connexin mapping data Circulation 109 2004 1172-1179
72. T.N. James The internodal pathways of the human heart Prog Cardiovasc Dis 43 2001 495-535
73. J. Liebman Are there internodal tracts? Yes Int J Cardiol 7 1985 174-185
74. R.H. Anderson S.Y. Ho A.E. Becker Recent advances in cardiology 1984 Churchill Livingstone 1-26
75. J. Tranum-Jensen F. Bojsen-Moller The ultrastructure of the sinuatrial ring bundle and of the caudal extension of the sinus node in the right atrium of the rabbit heart Z Zellforsch Mikrosk Anat 138 1973 97-112
76. M.O. Masuda A. Paes de Carvalho Sinoatrial transmission and atrial invasion during normal rhythm in the rabbit heart Circ Res 37 1975 414-421
77. D.L. Davis A.V. Edwards A.L. Juraszek A. Phelps A. Wessels J.B.E. Burch A GATA-6 gene heart-region-specific enhancer provides a novel means to mark and probe a discrete component of the mouse cardiac conduction system Mech Dev 108 2001 105-119
78. M.A. McGuire J.M.T. De Bakker J.T. Vermeulen A.F.M. Moorman P. Loh B. Thibault et al. Atrioventricular junctional tissue. Discrepancy between histological and electrophysiological characteristics Circulation 94 1996 571-577
79. J.B. Morton P. Sanders A. Das J.K. Vohra P.B. Sparks J.M. Kalman Focal atrial tachycardia arising from the tricuspid annulus: electrophysiologic and electrocardiographic characteristics J Cardiovasc Electrophysiol 12 2001 653-659
80. C. Mallavarapu D. Schwartzman D.J. Callans C.D. Gottlieb F.E. Marchlinski Radiofrequency catheter ablation of atrial tachycardia with unusual left atrial sites of origin report of two cases Pacing Clin Electrophysiol 19 1996 988-992
81. P.M. Kistler P. Sanders A. Hussin J.B. Morton J.K. Vohra P.B. Sparks et al. Focal atrial tachycardia arising from the mitral annulus: electrocardiographic and electrophysiologic characterization J Am Coll Cardiol 41 2003 2212-2219
82. S.Y. Ho J.A. Cabrera V.H. Tran J. Farre R.H. Anderson D. Sanchez-Quintana Architecture of the pulmonary veins: Relevance to radiofrequency ablation Heart 86 2001 265-270
83. J.G. Mönckeberg Zur Entwicklungsgeschichte des Atrioventrikularsystems Dtsch Pathol Ges 16 1913 228-249
84. F. Rothenberg V.P.M. Nikolski M. Watanabe R. Efimov Electrophysiology and anatomy of embryonic rabbit hearts before and after septation Am J Physiol 288 2005 H344-H351
85. E.T. Chuck M. Watanabe Differential expression of PSA-NCAM and HNK-1 Epitopes in the developing cardiac conduction system of the chick Dev Dyn 209 1997 182-195
86. L. Kanagaratnam G. Tomassoni R. Schweikert S. Pavia D. Bash S. Beheiry et al. Ventricular tachycardias arising from the aortic sinus of valsalva an under-recognized variant of left outflow tract ventricular tachycardia J Am Coll Cardiol 37 2001 1408-1414
87. L.M. Rodriguez J.L. Smeets C. Timmermans H.J. Wellens Predictors for successful ablation of right- and left-sided idiopathic ventricular tachycardia Am J Cardiol 79 1997 309-314
88. C. Timmermans L.M. Rodriguez H.J.G.M. Crijns A.F.M. Moorman H.J.J. Wellens Idiopathic left bundle branch block shaped ventricular tachycardia may originate above the pulmonary valve Circulation 108 2003 1960-1967
89. A.F.M. Moorman C.A. Schumacher P.A.J. de Boer J. Hagoort K. Bezstarosti M.J.B. van den Hoff et al. Presence of functional sarcoplasmic reticulum in the developing heart and its confinement to chamber myocardium Dev Biol 223 2000 279-290
90. C.E. Hall R. Hurtado K.W. Hewett M. Shulimovich C.P. Poma M. Reckova et al. Hemodynamic-dependent patterning of endothelin converting enzyme 1 expression and differentiation of impulse-conducting Purkinje fibers in the embryonic heart Development 131 2004 581-592
91. R.G. Gourdie T. Mima R.P. Thompson T. Mikawa Terminal diversification of the myocyte lineage generates Purkinje fibers of the cardiac conduction system Development 121 1995 1423-1431
92. G. Cheng W.H. Litchenberg G.J. Cole T. Mikawa R.P. Thompson R.G. Gourdie Development of the cardiac conduction system involves recruitment within a multipotent cardiomyogenic lineage Development 126 1999 5041-5049
93. B.M. Patten Initiation and early changes in the character of the heartbeat in vertebrate embryos Physiol Rev 29 1949 31-47
94. R.P. Kondo R.H. Anderson S. Kupershmidt D.M. Roden S.M. Evans Development of the cardiac conduction system as delineated by minK-lacZ J Cardiovasc Electrophysiol 14 2003 383-391
95. R.P. Thompson J.R. Lindroth Y.M.M. Wong Regional differences in DNA-synthetic activity in the preseptation myocardium of the chick 1990 219-234
96. D. Sedmera M. Reckova A. DeAlmeida M. Sedmerova M. Biermann J. Volejnik et al. Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus hearts Am J Physiol Heart Circ Physiol 284 2003 H1152-H1160
97. R.H. Anderson S.Y. Ho Structure and location of accessory muscular atrioventricular connections J Cardiovasc Electrophysiol 10 1999 1119-1123
98. M.S. Spach J.M. Kootsey The nature of electrical propagation in cardiac muscle Am J Physiol 244 1983 H3-H22