메뉴 건너뛰기




Volumn 3, Issue 12, 2004, Pages 1283-1289

RNA interference: A potential strategy for isoform-specific phosphatidylinositol 3-kinase targeted therapy in ovarian cancer

Author keywords

Ovarian cancer; PI3 kinase; PIK3CA; RNA interference

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; ISOPROTEIN; PIK3CA PROTEIN, HUMAN; TUMOR MARKER;

EID: 22344446375     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.3.12.1388     Document Type: Article
Times cited : (17)

References (41)
  • 1
    • 0033856462 scopus 로고    scopus 로고
    • PI3-kinase inhibition: A target for drug development?
    • Stein RC, Waterfield MD. PI3-kinase inhibition: A target for drug development? Mol Med Today 2000; 6:347-57.
    • (2000) Mol Med Today , vol.6 , pp. 347-357
    • Stein, R.C.1    Waterfield, M.D.2
  • 2
    • 0035190026 scopus 로고    scopus 로고
    • Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer
    • Katso R, Okkenhaug K, Ahmadi K, White S, Timms J, Waterfield MD. Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001; 17:615-75.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 615-675
    • Katso, R.1    Okkenhaug, K.2    Ahmadi, K.3    White, S.4    Timms, J.5    Waterfield, M.D.6
  • 3
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 4
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296:1655-7.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 10
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26:199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 11
    • 0036788304 scopus 로고    scopus 로고
    • Gene silencing in mammals by small interfering RNAs
    • McManus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nat Rev Genet 2002; 3:737-47.
    • (2002) Nat Rev Genet , vol.3 , pp. 737-747
    • McManus, M.T.1    Sharp, P.A.2
  • 12
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature 2002; 418:244-51.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 13
    • 0037213559 scopus 로고    scopus 로고
    • Mammalian RNAi for the masses
    • Shi Y. Mammalian RNAi for the masses. Trends Genet 2003; 19:9-12.
    • (2003) Trends Genet , vol.19 , pp. 9-12
    • Shi, Y.1
  • 15
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2:243-7.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 16
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • USA
    • Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99:6047-52.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 17
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
    • USA
    • Sui G, Soohoo C, Affar el B, Gay F, Shi Y, Forrester WC. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99:5515-20.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 5515-5520
    • Sui, G.1    Soohoo, C.2    El Affar, B.3    Gay, F.4    Shi, Y.5    Forrester, W.C.6
  • 18
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296:550-3.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 19
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison PJ, Gaudy AA, Bernstein E, Hannon GJ, Conklin DS. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002; 16:948-58.
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Gaudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 20
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul CP, Good PD, Winer I, Engelke DR. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002; 20:505-8.
    • (2002) Nat Biotechnol , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 21
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi M, Taira K. U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 2002; 20:497-500.
    • (2002) Nat Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 23
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y, Wagner EJ, Cullen BR. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 2002; 9:1327-33.
    • (2002) Mol Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 29
    • 0036899148 scopus 로고    scopus 로고
    • Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma
    • Zhang L, Yang N, Garcia JR, Mohamed A, Benencia F, Rubin SC, Allman D, Coukos G. Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma. Am J Pathol 2002; 161:2295-309.
    • (2002) Am J Pathol , vol.161 , pp. 2295-2309
    • Zhang, L.1    Yang, N.2    Garcia, J.R.3    Mohamed, A.4    Benencia, F.5    Rubin, S.C.6    Allman, D.7    Coukos, G.8
  • 30
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-8.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 31
    • 0036245743 scopus 로고    scopus 로고
    • Expanding small RNA interference
    • Tuschl T. Expanding small RNA interference. Nat Biotechnol 2002; 20:446-8.
    • (2002) Nat Biotechnol , vol.20 , pp. 446-448
    • Tuschl, T.1
  • 32
    • 0029949294 scopus 로고    scopus 로고
    • Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: A comparative study
    • Ilves H, Barske C, Junker U, Bohnlein E, Veres G. Retroviral vectors designed for targeted expression of RNA polymerase III-driven transcripts: A comparative study. Gene 1996; 171:203-8.
    • (1996) Gene , vol.171 , pp. 203-208
    • Ilves, H.1    Barske, C.2    Junker, U.3    Bohnlein, E.4    Veres, G.5
  • 33
    • 0037021437 scopus 로고    scopus 로고
    • Small interfering RNA and gene silencing in transgenic mice and rats
    • Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett 2002; 532:227-30.
    • (2002) FEBS Lett , vol.532 , pp. 227-230
    • Hasuwa, H.1    Kaseda, K.2    Einarsdottir, T.3    Okabe, M.4
  • 34
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • USA
    • Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003; 100:183-8.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 35
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • USA
    • Tiscornia G, Singer O, Ikawa M, Verma IM. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA 2003; 100:1844-8.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 36
    • 0036811055 scopus 로고    scopus 로고
    • Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs
    • Hamada M, Ohtsuka T, Kawaida R, Koizumi M, Morita K, Furukawa H, Imanishi T, Miyagishi M, Taira K. Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs. Antisense Nucleic Acid Drug Dev 2002; 12:301-9.
    • (2002) Antisense Nucleic Acid Drug Dev , vol.12 , pp. 301-309
    • Hamada, M.1    Ohtsuka, T.2    Kawaida, R.3    Koizumi, M.4    Morita, K.5    Furukawa, H.6    Imanishi, T.7    Miyagishi, M.8    Taira, K.9
  • 37
  • 38
    • 19444386359 scopus 로고    scopus 로고
    • Gene silencing in alveolar type II cells using cell-specific promoter in vitro and in vivo
    • Gou D, Narasaraju T, Chintagari NR, Jin N, Wang P, Liu L. Gene silencing in alveolar type II cells using cell-specific promoter in vitro and in vivo. Nucleic Acids Res 2004; 32:e134.
    • (2004) Nucleic Acids Res , vol.32
    • Gou, D.1    Narasaraju, T.2    Chintagari, N.R.3    Jin, N.4    Wang, P.5    Liu, L.6
  • 39
    • 0029119992 scopus 로고
    • Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells
    • Godwin AK, Miller PD, Getts LA, Jackson K, Sonoda G, Schray KJ, Testa JR, Hamilton TC. Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells. Endocrinology 1995; 136:4640-9.
    • (1995) Endocrinology , vol.136 , pp. 4640-4649
    • Godwin, A.K.1    Miller, P.D.2    Getts, L.A.3    Jackson, K.4    Sonoda, G.5    Schray, K.J.6    Testa, J.R.7    Hamilton, T.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.