Protective effect of apigenin on radiation-induced chromosomal damage in human lymphocytes

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 585, Issue 1-2, 2005, Pages 96-104

  Rithidech, Kanokporn Noy ^a   Tungjai, Montree ^a   Whorton, Elbert B ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apigenin; Flavonoids; Micronuclei; Radiation; Radioprotector

Indexed keywords

APIGENIN; CYTOCHALASIN B; RADIOPROTECTIVE AGENT;

ARTICLE; BLOOD SAMPLING; CALCULATION; CELL CULTURE; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GAMMA IRRADIATION; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RADIATION PROTECTION; STATISTICAL SIGNIFICANCE;

NASA DISCIPLINE RADIATION HEALTH; NON-NASA CENTER;

ADULT; APIGENIN; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINESIS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA RAYS; HUMANS; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; RADIATION-PROTECTIVE AGENTS;

EID: 22144498089     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2005.04.003     Document Type: Article

References (53)

1. E. Hall Radiobiology for the Radiologist fifth ed. 2000 Lippincott Williams New York
2. G. Storz, and J.A. Imlay Oxidative stress Curr. Opin. Microbiol. 2 1999 188 194
3. N.D. Turner, L.A. Braby, J. Ford, and J.R. Lupton Opportunities for nutritional amelioration of radiation-induced cellular damage Nutrition 18 2002 904 912
4. A.R. Collins Oxidative DNA damage, antioxidants, and cancer Bioessays 21 1999 238 246
5. B. Halliwell Effect of diet on cancer development: is oxidative DNA damage a biomarker? Free Radic. Biol. Med. 32 2002 968 974
6. J.A. Ross, and C.M. Kasum Dietary flavonoids: bioavailability, metabolic effects, and safety Annu. Rev. Nutr. 22 2002 19 34
7. A. Saija, M. Scalese, M. Lanza, D. Marzullo, F. Bonina, and F. Castelli Flavonoids as antioxidant agents: importance of their interaction with biomembranes Free Radic. Biol. Med. 19 1995 481 486
8. 2+ ions: implications for their antioxidant properties Biochem. J. 330 Pt 3 1998 1173 1178
9. D. Romanova, A. Vachalkova, L. Cipak, Z. Ovesna, and P. Rauko Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method Neoplasma 48 2001 104 107
10. K.H. Miean, and S. Mohamed Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants J. Agric. Food Chem. 49 2001 3106 3112
11. S. F'Guyer, F. Afaq, and H. Mukhtar Photochemoprevention of skin cancer by botanical agents Photodermatol. Photoimmunol. Photomed. 19 2003 56 72
12. H. Wei, L. Tye, E. Bresnick, and D.F. Birt Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice Cancer Res. 50 1990 499 502
13. T. Hirano, K. Oka, and M. Akiba Antiproliferative effects of synthetic and naturally occurring flavonoids on tumor cells of the human breast carcinoma cell line, ZR-75-1 Res. Commun. Chem. Pathol. Pharmacol. 64 1989 69 78
14. R.S. Rosenberg, L. Grass, D.J. Jenkins, C.W. Kendall, and E.P. Diamandis Modulation of androgen and progesterone receptors by phytochemicals in breast cancer cell lines Biochem. Biophys. Res. Commun. 248 1998 935 939
15. T. Kobayashi, T. Nakata, and T. Kuzumaki Effect of flavonoids on cell cycle progression in prostate cancer cells Cancer Lett. 176 2002 17 23
16. S. Caltagirone, C. Rossi, A. Poggi, F.O. Ranelletti, P.G. Natali, M. Brunetti, F.B. Aiello, and M. Piantelli Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential Int. J. Cancer 87 2000 595 600
17. F. Yin, A.E. Giuliano, and A.J. Van Herle Growth inhibitory effects of flavonoids in human thyroid cancer cell lines Thyroid 9 1999 369 376
18. D.M. Lepley, B. Li, D.F. Birt, and J.C. Pelling The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes Carcinogenesis 17 1996 2367 2375
19. M. McVean, W.C. Weinberg, and J.C. Pelling A p21(waf1)-independent pathway for inhibitory phosphorylation of cyclin-dependent kinase p34(cdc2) and concomitant G(2)/M arrest by the chemopreventive flavonoid apigenin Mol. Carcinog. 33 2002 36 43
20. S. Gupta, F. Afaq, and H. Mukhtar Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells Biochem. Biophys. Res. Commun. 287 2001 914 920
21. S. Gupta, F. Afaq, and H. Mukhtar Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells Oncogene 21 2002 3727 3738
22. C. Chaumontet, C. Droumaguet, V. Bex, C. Heberden, I. Gaillard-Sanchez, and P. Martel Flavonoids (apigenin, tangeretin) counteract tumor promoter-induced inhibition of intercellular communication of rat liver epithelial cells Cancer Lett. 114 1997 207 210
23. D.F. Birt, B. Walker, M.G. Tibbels, and E. Bresnick Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol Carcinogenesis 7 1986 959 963
24. M.L. Kuo, K.C. Lee, and J.K. Lin Genotoxicities of nitropyrenes and their modulation by apigenin, tannic acid, ellagic acid and indole-3-carbinol in the Salmonella and CHO systems Mutat. Res. 270 1992 87 95
25. J.K. Lin, Y.C. Chen, Y.T. Huang, and S.Y. Lin-Shiau Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin J. Cell. Biochem. Suppl. 28-29 1997 39 48
26. M.L. Kuo, and N.C. Yang Reversion of v-H-ras-transformed NIH 3T3 cells by apigenin through inhibiting mitogen activated protein kinase and its downstream oncogenes Biochem. Biophys. Res. Commun. 212 1995 767 775
27. T. Fotsis, M.S. Pepper, E. Aktas, S. Breit, S. Rasku, H. Adlercreutz, K. Wahala, R. Montesano, and L. Schweigerer Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis Cancer Res. 57 1997 2916 2921
28. Y.C. Liang, Y.T. Huang, S.H. Tsai, S.Y. Lin-Shiau, C.F. Chen, and J.K. Lin Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages Carcinogenesis 20 1999 1945 1952
29. R.D. Snyder, and P.J. Gillies Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells Environ. Mol. Mutagen. 40 2002 266 276
30. M. Fenech, and A.A. Morley Measurement of micronuclei in lymphocytes Mutat. Res. 147 1985 29 36
31. M. Fenech, and A. Morley Solutions to the kinetic problem in the micronucleus assay Cytobios 43 1985 233 246
32. M. Fenech, and A.A. Morley The effect of donor age on spontaneous and induced micronuclei Mutat. Res. 148 1985 99 105
33. M. Fenech, and A.A. Morley Cytokinesis-block micronucleus method in human lymphocytes: effect of in vivo ageing and low dose X-irradiation Mutat. Res. 161 1986 193 198
34. M. Fenech, W.P. Chang, M. Kirsch-Volders, N. Holland, S. Bonassi, and E. Zeiger HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures Mutat. Res. 534 2003 65 75
35. A. Ramalho, I. Sunjevaric, and A.T. Natarajan Use of the frequencies of micronuclei as quantitative indicators of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes: comparison of two methods Mutat. Res. 207 1988 141 146
36. J. Surralles, N. Xamena, A. Creus, J. Catalan, H. Norppa, and R. Marcos Induction of micronuclei by five pyrethroid insecticides in whole-blood and isolated human lymphocyte cultures Mutat. Res. 341 1995 169 184
37. C. Manach, A. Scalbert, C. Morand, C. Remesy, and L. Jimenez Polyphenols: food sources and bioavailability Am. J. Clin. Nutr. 79 2004 727 747
38. S.E. Nielsen, J.F. Young, B. Daneshvar, S.T. Lauridsen, P. Knuthsen, B. Sandstrom, and L.O. Dragsted Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects Br. J. Nutr. 81 1999 447 455
39. A. Gradolatto, M.C. Canivenc-Lavier, J.P. Basly, M.H. Siess, and C. Teyssier Metabolism of apigenin by rat liver phase I and phase II enzymes and by isolated perfused rat liver Drug Metab. Dispos. 32 2004 58 65
40. J. Chen, H. Lin, and M. Hu Metabolism of flavonoids via enteric recycling: role of intestinal disposition J. Pharmacol. Exp. Ther. 304 2003 1228 1235
41. P. Jacquet, L. de Saint-Georges, S. Barrio, and L. Baugnet-Mahieu Morphological effects of caffeine, okadaic acid and genistein in one-cell mouse embryos blocked in G2 by X-irradiation Int. J. Radiat. Biol. 67 1995 347 358
42. K. Shimoi, S. Masuda, B. Shen, M. Furugori, and N. Kinae Radioprotective effects of antioxidative plant flavonoids in mice Mutat. Res. 350 1996 153 161
43. G.C. Jagetia, and T.K. Reddy The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow: a micronucleus study Mutat. Res. 519 2002 37 48
44. N.G. Oliveira, M. Neves, A.S. Rodrigues, O. Monteiro Gil, T. Chaveca, and J. Rueff Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay Mutagenesis 15 2000 77 83
45. S.M. Morris, J.J. Chen, O.E. Domon, L.J. McGarrity, M.E. Bishop, M.G. Manjanatha, and D.A. Casciano p53, mutations, and apoptosis in genistein-exposed human lymphoblastoid cells Mutat. Res. 405 1998 41 56
46. M.Y. Heo, S.J. Sohn, and W.W. Au Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate Mutat. Res. 488 2001 135 150
47. J. da Silva, S.M. Herrmann, V. Heuser, W. Peres, N. Possa Marroni, J. Gonzalez-Gallego, and B. Erdtmann Evaluation of the genotoxic effect of rutin and quercetin by comet assay and micronucleus test Food Chem. Toxicol. 40 2002 941 947
48. G.C. Jagetia, M.S. Baliga, K.J. Malagi, and M. Sethukumar Kamath The evaluation of the radioprotective effect of Triphala (an ayurvedic rejuvenating drug) in the mice exposed to gamma-radiation Phytomedicine 9 2002 99 108
49. G.C. Jagetia, and M.S. Baliga Treatment of mice with a herbal preparation (mentat) protects against radiation-induced mortality Phytother. Res. 17 2003 876 881
50. A.S. Baldwin Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights Annu. Rev. Immunol. 14 1996 649 683
51. Z.G. Liu, H. Hsu, D.V. Goeddel, and M. Karin Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death Cell 87 1996 565 576
52. C.Y. Wang, M.W. Mayo, and A.S. Baldwin Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB Science 274 1996 784 787
53. R.R. Weichselbaum, D. Hallahan, Z. Fuks, and D. Kufe Radiation induction of immediate early genes: effectors of the radiation-stress response Int. J. Radiat. Oncol. Biol. Phys. 30 1994 229 234