Metabolism of apigenin by rat liver phase I and phase II enzymes and by isolated perfused rat liver

Drug Metabolism and Disposition

Volumn 32, Issue 1, 2004, Pages 58-65

  Gradolatto, Angéline ^a   Canivenc Lavier, Marie Chantal ^a   Basly, Jean Philippe ^a,b   Siess, Marie Hélène ^a   Teyssier, Caroline ^a  

^a CEMAGREF   (France)

^b UNIVERSITY OF LIMOGES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B; CYTOCHROME P450 2E1; CYTOCHROME P450 INHIBITOR; CYTOCHROME P450 OXYGENASE; DIOSMETIN; ESTROGEN DERIVATIVE; FLAVANONE; GENISTEIN; GLUCURONIC ACID; ISOFLAVONE; ISOSCUTELLAREIN; KAEMPFEROL; LUTEOLIN; METHYL GROUP; NARINGENIN; SCUTELLAREIN; SULFUR DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONJUGATE; CONJUGATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG METABOLISM; ENZYME INHIBITION; ESTROGEN ACTIVITY; EX VIVO STUDY; FEMALE; GLUCURONIDATION; HYDROXYLATION; IN VITRO STUDY; ISOLATION PROCEDURE; LIVER METABOLISM; LIVER PERFUSION; MALE; METABOLIC REGULATION; NONHUMAN; OXIDATION KINETICS; PHYTOCHEMISTRY; PRIORITY JOURNAL; PRODUCT RECOVERY; RAT;

ANIMALS; APIGENIN; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; FMN REDUCTASE; GLUCURONIDES; KINETICS; LIVER; LUTEOLIN; MALE; MASS SPECTROMETRY; METHYLATION; NADP; RATS; RATS, WISTAR; SEX CHARACTERISTICS; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBCELLULAR FRACTIONS; SULFATES;

ANIMALIA;

EID: 1642539168     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.1.58     Document Type: Article

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