메뉴 건너뛰기




Volumn 9, Issue 10, 2004, Pages 962-967

Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families

Author keywords

Association; Catechol o methyltransferase; Irish families; LD structure and haplotype; Schizophrenia; TDT tests

Indexed keywords

ADRENALIN; CATECHOL METHYLTRANSFERASE; CATECHOLAMINE; DOPAMINE; METHIONINE; NEUROTRANSMITTER; NORADRENALIN; S ADENOSYLMETHIONINE; VALINE;

EID: 6044246071     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001519     Document Type: Article
Times cited : (111)

References (46)
  • 1
    • 0037439153 scopus 로고    scopus 로고
    • Catechol O-methyltransferase mRNA expression in human and rat brain: Evidence for a role in cortical neuronal function
    • Matsumoto M, Weickert CS, Akil M, Lipska BK, Hyde TM, Hermann MM et al. Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function. Neuroscience 2003; 116: 127-137.
    • (2003) Neuroscience , vol.116 , pp. 127-137
    • Matsumoto, M.1    Weickert, C.S.2    Akil, M.3    Lipska, B.K.4    Hyde, T.M.5    Hermann, M.M.6
  • 2
    • 0029874880 scopus 로고    scopus 로고
    • A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12
    • Schizophrenia Collaborative Linkage Group (Chromosome 22)
    • Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R et al. A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). Am J Med Genet 1996; 67: 40-45.
    • (1996) Am J Med Genet , vol.67 , pp. 40-45
    • Gill, M.1    Vallada, H.2    Collier, D.3    Sham, P.4    Holmans, P.5    Murray, R.6
  • 3
    • 0031718093 scopus 로고    scopus 로고
    • Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family set
    • Hovatta I, Lichtermann D, Juvonen H, Suvisaari J, Terwilliger JD, Arajarvi R et al. Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family set. Mol Psychiatry 1998; 3: 452-457.
    • (1998) Mol Psychiatry , vol.3 , pp. 452-457
    • Hovatta, I.1    Lichtermann, D.2    Juvonen, H.3    Suvisaari, J.4    Terwilliger, J.D.5    Arajarvi, R.6
  • 5
    • 0035089756 scopus 로고    scopus 로고
    • Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
    • Curling HM, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS et al. Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet 2001; 68: 661-673.
    • (2001) Am J Hum Genet , vol.68 , pp. 661-673
    • Curling, H.M.1    Kalsi, G.2    Brynjolfson, J.3    Sigmundsson, T.4    Sherrington, R.5    Mankoo, B.S.6
  • 6
    • 0029848377 scopus 로고    scopus 로고
    • No evidence for linkage of chromosome 22 markers to schizophrenia in southern African Bantu-speaking families
    • Riley B, Mogudi-Carter M, Jenkins T, Williamson R. No evidence for linkage of chromosome 22 markers to schizophrenia in southern African Bantu-speaking families. Am J Med Genet 1996; 67: 515-522.
    • (1996) Am J Med Genet , vol.67 , pp. 515-522
    • Riley, B.1    Mogudi-Carter, M.2    Jenkins, T.3    Williamson, R.4
  • 7
    • 0036024256 scopus 로고    scopus 로고
    • Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes
    • Straub RE, MacLean CJ, Ma Y, Webb BT, Myakishev MV, Harris-Kerr C et al. Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes. Mol Psychiatry 2002; 7: 542-559.
    • (2002) Mol Psychiatry , vol.7 , pp. 542-559
    • Straub, R.E.1    MacLean, C.J.2    Ma, Y.3    Webb, B.T.4    Myakishev, M.V.5    Harris-Kerr, C.6
  • 8
    • 0032858459 scopus 로고    scopus 로고
    • A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs
    • Williams NM, Rees MI, Holmans P, Norton N, Cardno AG, Jones LA et al. A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs. Hum Mol Genet 1999; 8: 1729-1739.
    • (1999) Hum Mol Genet , vol.8 , pp. 1729-1739
    • Williams, N.M.1    Rees, M.I.2    Holmans, P.3    Norton, N.4    Cardno, A.G.5    Jones, L.A.6
  • 12
    • 0037365978 scopus 로고    scopus 로고
    • Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: Meta-analysis of case-control and family-based studies
    • Glatt SJ, Faraone SV, Tsuang MT. Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies. Am J Psychiatry 2003; 160: 469-476.
    • (2003) Am J Psychiatry , vol.160 , pp. 469-476
    • Glatt, S.J.1    Faraone, S.V.2    Tsuang, M.T.3
  • 13
    • 0033966919 scopus 로고    scopus 로고
    • Family-based linkage disequilibrium mapping using SNP marker haplotypes: Application to a potential locus for schizophrenia at chromosome 22q11
    • Li T, Ball D, Zhao J, Murray RM, Liu X, Sham PC et al. Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11. Mol Psychiatry 2000; 5: 77-84.
    • (2000) Mol Psychiatry , vol.5 , pp. 77-84
    • Li, T.1    Ball, D.2    Zhao, J.3    Murray, R.M.4    Liu, X.5    Sham, P.C.6
  • 14
    • 0031910582 scopus 로고    scopus 로고
    • Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics
    • Ohmori O, Shinkai T, Kojima H, Terao T, Suzuki T, Mita T et al. Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics. Neurosci Lett 1998; 243: 109-112.
    • (1998) Neurosci Lett , vol.243 , pp. 109-112
    • Ohmori, O.1    Shinkai, T.2    Kojima, H.3    Terao, T.4    Suzuki, T.5    Mita, T.6
  • 15
    • 0037114834 scopus 로고    scopus 로고
    • Eye movement disturbances in schizophrenia and a polymorphism of catechol-O-methyltransferase gene
    • Rybakowski JK, Borkowska A, Czerski PM, Hauser J. Eye movement disturbances in schizophrenia and a polymorphism of catechol-O-methyltransferase gene. Psychiatry Res 2002; 113: 49-57.
    • (2002) Psychiatry Res , vol.113 , pp. 49-57
    • Rybakowski, J.K.1    Borkowska, A.2    Czerski, P.M.3    Hauser, J.4
  • 17
    • 0030889078 scopus 로고    scopus 로고
    • Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: Evidence for association with aggressive and antisocial behavior
    • Strous RD, Bark N, Parsia SS, Volavka J, Lachman HM. Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: evidence for association with aggressive and antisocial behavior. Psychiatry Res 1997; 69: 71-77.
    • (1997) Psychiatry Res , vol.69 , pp. 71-77
    • Strous, R.D.1    Bark, N.2    Parsia, S.S.3    Volavka, J.4    Lachman, H.M.5
  • 18
    • 0034176019 scopus 로고    scopus 로고
    • Ultradian rapid cycling in prepubertal and early adolescent bipolarity is not in transmission disequilibrium with val/met COMT alleles
    • Geller B, Cook Jr EH. Ultradian rapid cycling in prepubertal and early adolescent bipolarity is not in transmission disequilibrium with val/met COMT alleles. Biol Psychiatry 2000; 47; 605-609.
    • (2000) Biol Psychiatry , vol.47 , pp. 605-609
    • Geller, B.1    Cook Jr., E.H.2
  • 19
    • 0029745410 scopus 로고    scopus 로고
    • Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome
    • Lachman HM, Morrow B, Shprintzen R, Veit S, Parsia SS, Faedda G et al. Association of codon 108/158 catechol-O-methyltransferase gene polymorphism with the psychiatric manifestations of velo-cardio-facial syndrome. Am J Med Genet 1996; 67: 468-472.
    • (1996) Am J Med Genet , vol.67 , pp. 468-472
    • Lachman, H.M.1    Morrow, B.2    Shprintzen, R.3    Veit, S.4    Parsia, S.S.5    Faedda, G.6
  • 20
    • 0037947438 scopus 로고    scopus 로고
    • Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine
    • Mattay VS, Goldberg TE, Fera F, Hariri AR, Tessitore A, Egan MF et al. Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine. Proc Natl Acad Sci USA 2003; 100: 6186-6191.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6186-6191
    • Mattay, V.S.1    Goldberg, T.E.2    Fera, F.3    Hariri, A.R.4    Tessitore, A.5    Egan, M.F.6
  • 21
    • 0038094426 scopus 로고    scopus 로고
    • A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits
    • Rujescu D, Giegling I, Gietl A, Hartmann AM, Moller HJ. A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits. Biol Psychiatry 2003; 54: 34-39.
    • (2003) Biol Psychiatry , vol.54 , pp. 34-39
    • Rujescu, D.1    Giegling, I.2    Gietl, A.3    Hartmann, A.M.4    Moller, H.J.5
  • 22
    • 0037468289 scopus 로고    scopus 로고
    • Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females
    • Tsai SJ, Yu YW, Chen TJ, Chen JY, Liou YJ, Chen MC et al. Association study of a functional catechol-O-methyltransferase-gene polymorphism and cognitive function in healthy females. Neurosci Lett 2003; 338: 123-126.
    • (2003) Neurosci Lett , vol.338 , pp. 123-126
    • Tsai, S.J.1    Yu, Y.W.2    Chen, T.J.3    Chen, J.Y.4    Liou, Y.J.5    Chen, M.C.6
  • 23
    • 0033573290 scopus 로고    scopus 로고
    • Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity
    • Kotler M, Barak P, Cohen H, Averbuch IE, Grinshpoon A, Gritsenko I et al. Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity. Am J Med Genet 1999; 88: 628-633.
    • (1999) Am J Med Genet , vol.88 , pp. 628-633
    • Kotler, M.1    Barak, P.2    Cohen, H.3    Averbuch, I.E.4    Grinshpoon, A.5    Gritsenko, I.6
  • 24
    • 0041413380 scopus 로고    scopus 로고
    • Association between Val108/158 Met polymorphism of the COMT gene and schizophrenia
    • Wonodi I, Stine OC, Mitchell BD, Buchanan RW, Thaker GK. Association between Val108/158 Met polymorphism of the COMT gene and schizophrenia. Am J Med Genet 2003; 120B: 47-50.
    • (2003) Am J Med Genet , vol.120 B , pp. 47-50
    • Wonodi, I.1    Stine, O.C.2    Mitchell, B.D.3    Buchanan, R.W.4    Thaker, G.K.5
  • 25
    • 0035985465 scopus 로고    scopus 로고
    • Family-based association studies of COMT gene polymorphisms and schizophrenia in the Chinese population
    • Fan JB, Chen WY, Tang JX, Li S, Gu NF, Feng GY et al. Family-based association studies of COMT gene polymorphisms and schizophrenia in the Chinese population. Mol Psychiatry 2002; 7: 446-447.
    • (2002) Mol Psychiatry , vol.7 , pp. 446-447
    • Fan, J.B.1    Chen, W.Y.2    Tang, J.X.3    Li, S.4    Gu, N.F.5    Feng, G.Y.6
  • 26
    • 10744225915 scopus 로고    scopus 로고
    • Family-based and case-control study of catechol-O-methyl-transferase in schizophrenia among Palestinian Arabs
    • Kremer I, Pinto M, Murad I, Muhaheed M, Bannoura I, Muller DJ et al. Family-based and case-control study of catechol-O-methyl-transferase in schizophrenia among Palestinian Arabs. Am J Med Genet 2003; 119B: 35-39.
    • (2003) Am J Med Genet , vol.119 B , pp. 35-39
    • Kremer, I.1    Pinto, M.2    Murad, I.3    Muhaheed, M.4    Bannoura, I.5    Muller, D.J.6
  • 27
    • 9844257590 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase polymorphisms and schizophrenia: A transmission disequilibrium study in multiply affected families
    • Kunugi H, Vallada HP, Sham PC, Hoda F, Arranz MJ, Li T et al. Catechol-O-methyltransferase polymorphisms and schizophrenia: a transmission disequilibrium study in multiply affected families. Psychiatr Genet 1997; 7: 97-101.
    • (1997) Psychiatr Genet , vol.7 , pp. 97-101
    • Kunugi, H.1    Vallada, H.P.2    Sham, P.C.3    Hoda, F.4    Arranz, M.J.5    Li, T.6
  • 28
    • 0035116424 scopus 로고    scopus 로고
    • Family-based association studies of monoaminergic gene polymorphisms among North Indians with schizophrenia
    • Semwal P, Prasad S, Bhatia T, Deshpande SN, Wood J, Nimgaonkar VL et al. Family-based association studies of monoaminergic gene polymorphisms among North Indians with schizophrenia. Mol Psychiatry 2001; 6: 220-224.
    • (2001) Mol Psychiatry , vol.6 , pp. 220-224
    • Semwal, P.1    Prasad, S.2    Bhatia, T.3    Deshpande, S.N.4    Wood, J.5    Nimgaonkar, V.L.6
  • 29
    • 0028918413 scopus 로고
    • Kinetics of human soluble and membrane-bound catechol O-methyltransferase: A revised mechanism and description of the thermolabile variant of the enzyme
    • Lotta T, Vidgren J, Tilgmann C, Ulmanen I, Melen K, Julkunen I et al. Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. Biochemistry 1995; 34: 4202-4210.
    • (1995) Biochemistry , vol.34 , pp. 4202-4210
    • Lotta, T.1    Vidgren, J.2    Tilgmann, C.3    Ulmanen, I.4    Melen, K.5    Julkunen, I.6
  • 30
    • 0038389841 scopus 로고    scopus 로고
    • A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain
    • Bray NJ, Buckland PR, Williams NM, Williams HJ, Norton N, Owen MJ et al. A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain. Am J Hum Genet 2003; 73: 152-161.
    • (2003) Am J Hum Genet , vol.73 , pp. 152-161
    • Bray, N.J.1    Buckland, P.R.2    Williams, N.M.3    Williams, H.J.4    Norton, N.5    Owen, M.J.6
  • 31
    • 10544251071 scopus 로고    scopus 로고
    • Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families
    • Kendler KS, MacLean CJ, O'Neill FA, Burke J, Murphy B, Duke F et al. Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families. Am J Psychiatry 1996; 153: 1534-1540.
    • (1996) Am J Psychiatry , vol.153 , pp. 1534-1540
    • Kendler, K.S.1    MacLean, C.J.2    O'Neill, F.A.3    Burke, J.4    Murphy, B.5    Duke, F.6
  • 32
    • 0034100029 scopus 로고    scopus 로고
    • Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p the Irish Study of High-Density Schizophrenia Families
    • Kendler KS, Myers JM, O'Neill FA, Martin R, Murphy B, MacLean CJ et al. Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p the Irish Study of High-Density Schizophrenia Families. Am J Psychiatry 2000; 157: 402-408.
    • (2000) Am J Psychiatry , vol.157 , pp. 402-408
    • Kendler, K.S.1    Myers, J.M.2    O'Neill, F.A.3    Martin, R.4    Murphy, B.5    MacLean, C.J.6
  • 33
    • 18444364206 scopus 로고    scopus 로고
    • Genetic variation in the 6p22.3 gene DTNBP1 the human ortholog of the mouse dysbindin gene, is associated with schizophrenia
    • Straub RE, Jiang Y, MacLean CJ, Ma Y, Webb BT, Myakishev MV et al. Genetic variation in the 6p22.3 gene DTNBP1 the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. Am J Hum Genet 2002; 71: 337-348.
    • (2002) Am J Hum Genet , vol.71 , pp. 337-348
    • Straub, R.E.1    Jiang, Y.2    MacLean, C.J.3    Ma, Y.4    Webb, B.T.5    Myakishev, M.V.6
  • 36
    • 0033058730 scopus 로고    scopus 로고
    • Fluorescence polarization in homogeneous nucleic acid analysis
    • Chen X, Levine L, Kwok PY. Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res 1999; 9: 492-498.
    • (1999) Genome Res , vol.9 , pp. 492-498
    • Chen, X.1    Levine, L.2    Kwok, P.Y.3
  • 37
    • 0037336629 scopus 로고    scopus 로고
    • FP-TDI SNP scoring by manual and statistical procedures: A study of error rates and types
    • van den Oord EJ, Jiang Y, Riley BP, Kendler KS, Chen X. FP-TDI SNP scoring by manual and statistical procedures: a study of error rates and types. Biotechniques 2003; 34: 610-620, 622.
    • (2003) Biotechniques , vol.34 , pp. 610-620
    • Van Den Oord, E.J.1    Jiang, Y.2    Riley, B.P.3    Kendler, K.S.4    Chen, X.5
  • 38
    • 0033237335 scopus 로고    scopus 로고
    • A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission
    • Clayton D. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Genet 1999; 65: 1170-1177.
    • (1999) Am J Hum Genet , vol.65 , pp. 1170-1177
    • Clayton, D.1
  • 39
    • 0033358595 scopus 로고    scopus 로고
    • Transmission/disequilibrium tests for extended marker haplotypes
    • Clayton D, Jones H. Transmission/disequilibrium tests for extended marker haplotypes. Am J Hum Genet 1999; 65: 1161-1169.
    • (1999) Am J Hum Genet , vol.65 , pp. 1161-1169
    • Clayton, D.1    Jones, H.2
  • 40
    • 0035055544 scopus 로고    scopus 로고
    • The family based association test method: Strategies for studying general genotype-phenotype associations
    • Horvath S, Xu X, Laird NM. The family based association test method: strategies for studying general genotype-phenotype associations. Eur J Hum Genet 2001; 9: 301-306.
    • (2001) Eur J Hum Genet , vol.9 , pp. 301-306
    • Horvath, S.1    Xu, X.2    Laird, N.M.3
  • 41
    • 0033814928 scopus 로고    scopus 로고
    • Implementing a unified approach to family-based tests of association
    • Laird NM, Horvath S, Xu X. Implementing a unified approach to family-based tests of association. Genet Epidemiol 2000; 19(Suppl 1): S36-S42.
    • (2000) Genet Epidemiol , vol.19 , Issue.SUPPL. 1
    • Laird, N.M.1    Horvath, S.2    Xu, X.3
  • 42
    • 0033910787 scopus 로고    scopus 로고
    • A test for linkage and association in general pedigrees: The pedigree disequilibrium test
    • Martin ER, Monks SA, Warren LL, Kaplan NL. A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet 2000; 67: 146-154.
    • (2000) Am J Hum Genet , vol.67 , pp. 146-154
    • Martin, E.R.1    Monks, S.A.2    Warren, L.L.3    Kaplan, N.L.4
  • 43
    • 0029945706 scopus 로고    scopus 로고
    • Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing statistics
    • Sobel E, Lange K. Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 1996; 58: 1323-1337.
    • (1996) Am J Hum Genet , vol.58 , pp. 1323-1337
    • Sobel, E.1    Lange, K.2
  • 44
    • 0035158118 scopus 로고    scopus 로고
    • Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan
    • Liou YJ, Tsai SJ, Hong CJ, Wang YC, Lai IC. Association analysis of a functional catechol-o-methyltransferase gene polymorphism in schizophrenic patients in Taiwan. Neuropsychobiology 2001; 43: 11-14.
    • (2001) Neuropsychobiology , vol.43 , pp. 11-14
    • Liou, Y.J.1    Tsai, S.J.2    Hong, C.J.3    Wang, Y.C.4    Lai, I.C.5
  • 45
    • 0033399702 scopus 로고    scopus 로고
    • Lack of evidence for association between the COMT locus and schizophrenia
    • Wei J, Hemmings GP. Lack of evidence for association between the COMT locus and schizophrenia. Psychiatr Genet 1999; 9: 183-186.
    • (1999) Psychiatr Genet , vol.9 , pp. 183-186
    • Wei, J.1    Hemmings, G.P.2
  • 46
    • 0028819262 scopus 로고
    • Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population
    • Risch N, de Leon D, Ozelius L, Kramer P, Almasy L, Singer B et al. Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population. Nat Genet 1995; 9: 152-159.
    • (1995) Nat Genet , vol.9 , pp. 152-159
    • Risch, N.1    De Leon, D.2    Ozelius, L.3    Kramer, P.4    Almasy, L.5    Singer, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.