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Volumn 13, Issue 16, 2005, Pages 4960-4971

Geldanamycin derivative inhibition of HGF/SF-mediated Met tyrosine kinase receptor-dependent urokinase-plasminogen activation

(6) Shen, Yuehai a Xie, Qian b Norberg, Monica a Sausville, Edward c Vande Woude, George b Wenkert, David a

a MICHIGAN STATE UNIVERSITY (United States)

b VAN ANDEL RESEARCH INSTITUTE (United States)

c NATIONAL CANCER INSTITUTE (United States)

Author keywords

Geldanamycin; Hepatocyte growth factor scatter factor; Met tyrosine kinase receptor; Urokinase plasminogen activation

Indexed keywords

11 O ACETYL 17 N AZETIDINYL 17 DEMETHOXYGELDANAMYCIN; 17 (2 ACETYLAMINOETHYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (2 CHLOROETHYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (2 DIMETHYLAMINOETHYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (2 FLUOROETHYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (6 ACETYLAMINOHEXYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (6 BIOTINYLAMINOHEXYL)AMINO 17 DEMETHOXYGELDANAMYCIN; 17 (8 ACETAMIDO 3,6 DIOXAOCTYLAMINO) 17 DEMETHOXYGELDANAMYCIN; 17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; 17 AMINO 17 DEMETHOXYGELDANAMYCIN; 17 CARBOXYMETHYLAMINO 17 DEMETHOXYGELDANAMYCIN; 17 N AZETIDINYL 17 DEMETHOXYGELDANAMYCIN; 17 N AZETIDINYL 7 DECARBAMYL 17 DEMETHOXYGELDANAMYCIN; 17 N AZIRIDINYL 17 DEMETHOXYGELDANAMYCIN; 5' BROMOGELDANOXAZONE; 5' IODOGELDANOXAZONE; ADENOSINE TRIPHOSPHATE; ANSAMYCIN DERIVATIVE; DIHYDROGELDANAMYCIN; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; MACBECIN I; MACBECIN II; RADICICOL; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; UROKINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVITY; NONHUMAN; PLASMINOGEN ACTIVATION; PROTEIN DOMAIN; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION;

BENZOQUINONES; CELL LINE, TUMOR; HEPATOCYTE GROWTH FACTOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; LACTONES; MACROLIDES; PROTEIN KINASE INHIBITORS; QUINONES; RECEPTORS, CELL SURFACE; RIFABUTIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 21744431834 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/j.bmc.2005.05.038 Document Type: Article

Times cited : (18)

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