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Volumn 11, Issue 3, 2004, Pages 325-335

Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy

Author keywords

Antisense; c Met; Growth factors; Liposomes; Lung cancer

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LIPOSOME; MITOGEN ACTIVATED PROTEIN KINASE; RIBONUCLEASE; RNA; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SMALL NUCLEAR RNA; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

EID: 1242296133     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302169     Document Type: Article
Times cited : (44)

References (74)
  • 1
    • 0022800175 scopus 로고
    • Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts
    • Cooper CS et al. Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts. EMBO J 1986; 10: 2623-2628.
    • (1986) EMBO J. , vol.10 , pp. 2623-2628
    • Cooper, C.S.1
  • 2
    • 1242348060 scopus 로고
    • Sequence of MET proto-oncogene cDNA has features characteristic of the tyrosine kinase family of growth factor receptors
    • Park M et al. Sequence of MET proto-oncogene cDNA has features characteristic of the tyrosine kinase family of growth factor receptors. Proc Natl Acad Sci USA 1987; 84: 379-6383.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 379-6383
    • Park, M.1
  • 3
    • 0025805633 scopus 로고
    • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
    • Bottaro DP et al. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991; 251: 802-804.
    • (1991) Science , vol.251 , pp. 802-804
    • Bottaro, D.P.1
  • 4
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura T, Nawa K, Ichihara A. Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 1984; 122: 1450-1459.
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 5
    • 0025771101 scopus 로고
    • Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor
    • Naldini L et al. Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J 1991; 10: 2867-2878.
    • (1991) EMBO J. , vol.10 , pp. 2867-2878
    • Naldini, L.1
  • 6
    • 0025119463 scopus 로고
    • Scatter factor: Molecular characteristics and effect on the invasiveness of epithelial cells
    • Weidner KM, Behrens J, Vandekerckhove J, Birchmeier W. Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells. J Cell Biol 1990; 111: 2097-2108.
    • (1990) J. Cell Biol. , vol.111 , pp. 2097-2108
    • Weidner, K.M.1    Behrens, J.2    Vandekerckhove, J.3    Birchmeier, W.4
  • 7
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M, Gherardi E, Peryman M, Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987; 327: 239-242.
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Peryman, M.3    Gray, J.4
  • 8
    • 0025307620 scopus 로고
    • Smooth muscle-derived factor stimulates mobility of human tumor cells
    • Rosen E et al. Smooth muscle-derived factor stimulates mobility of human tumor cells. Invasion Metas 1990; 10: 49-64.
    • (1990) Invasion Metas. , vol.10 , pp. 49-64
    • Rosen, E.1
  • 9
    • 0027633237 scopus 로고
    • Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells
    • Tsao MS et al. Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. Cell Growth Differ 1993; 4: 571-579.
    • (1993) Cell Growth Differ. , vol.4 , pp. 571-579
    • Tsao, M.S.1
  • 10
    • 0027052580 scopus 로고
    • Human lung cancer cell line producing hepatocyte growth factor/scatter factor
    • Yoshinaga Y et al. Human lung cancer cell line producing hepatocyte growth factor/scatter factor. Jpn J Cancer Res 1992; 83: 1257-1259.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 1257-1259
    • Yoshinaga, Y.1
  • 11
    • 0035067626 scopus 로고    scopus 로고
    • c-MET expression in myofibroblasts: Role in autocrine activation and prognostic significance in lung adenocarcinoma
    • Tokunou M et al. c-MET expression in myofibroblasts: role in autocrine activation and prognostic significance in lung adenocarcinoma. Am J Pathol 2001; 158: 1451-1463.
    • (2001) Am. J. Pathol. , vol.158 , pp. 1451-1463
    • Tokunou, M.1
  • 12
    • 0034129655 scopus 로고    scopus 로고
    • Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line
    • Yi S, Tsao MS. Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line. Neoplasia 2000; 2: 226-234.
    • (2000) Neoplasia , vol.2 , pp. 226-234
    • Yi, S.1    Tsao, M.S.2
  • 13
    • 0025824738 scopus 로고
    • Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
    • Montesano R, Matsumoto K, Nakamura T, Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 1991; 67: 901-908.
    • (1991) Cell , vol.67 , pp. 901-908
    • Montesano, R.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4
  • 14
    • 0030799090 scopus 로고    scopus 로고
    • Activating mutations for the met tyrosine kinase receptor in human cancer
    • Jeffers M et al. Activating mutations for the met tyrosine kinase receptor in human cancer. Proc Natl Acad Sci USA 1997; 94: 11445-11450.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11445-11450
    • Jeffers, M.1
  • 15
    • 0026655776 scopus 로고
    • Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
    • Rong S et al. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor. Mol Cell Biol 1992; 12: 5152-5158.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 5152-5158
    • Rong, S.1
  • 16
    • 0034673699 scopus 로고    scopus 로고
    • Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas
    • Di Renzo MF et al. Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas. Oncogene 2000; 19: 1547-1555.
    • (2000) Oncogene , vol.19 , pp. 1547-1555
    • Di Renzo, M.F.1
  • 17
    • 0036896226 scopus 로고    scopus 로고
    • Novel somatic mutations of the MET oncogene in human carcinoma metastases activating cell motility and invasion
    • Lorenzato A et al. Novel somatic mutations of the MET oncogene in human carcinoma metastases activating cell motility and invasion. Cancer Res 2002; 62: 7025-7030.
    • (2002) Cancer Res. , vol.62 , pp. 7025-7030
    • Lorenzato, A.1
  • 18
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the met proto-oncogene in papillary renal carcinomas
    • Schmidt L et al. Germline and somatic mutations in the tyrosine kinase domain of the met proto-oncogene in papillary renal carcinomas. Nat Genet 1997; 16: 68-73.
    • (1997) Nat. Genet. , vol.16 , pp. 68-73
    • Schmidt, L.1
  • 19
    • 0036022129 scopus 로고    scopus 로고
    • Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival
    • Qiao H et al. Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival. J Cell Biochem 2002; 86: 665-677.
    • (2002) J. Cell Biochem. , vol.86 , pp. 665-677
    • Qiao, H.1
  • 20
    • 0029889439 scopus 로고    scopus 로고
    • Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors
    • Liang TJ et al. Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors. J Clin Invest 1996; 97: 2872-2877.
    • (1996) J. Clin. Invest. , vol.97 , pp. 2872-2877
    • Liang, T.J.1
  • 21
    • 0031037754 scopus 로고    scopus 로고
    • Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor
    • Takayama H et al. Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci USA 1997; 94: 701-706.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 701-706
    • Takayama, H.1
  • 22
    • 0032523074 scopus 로고    scopus 로고
    • Expression of c-met is a strong independent prognostic factor in breast carcinoma
    • Ghoussoub RA et al. Expression of c-met is a strong independent prognostic factor in breast carcinoma. Cancer 1998; 82: 1513-1520.
    • (1998) Cancer , vol.82 , pp. 1513-1520
    • Ghoussoub, R.A.1
  • 23
    • 0028170110 scopus 로고
    • Overexpression of the Met/HGF receptor in ovarian cancer
    • Di Renzo MF et al. Overexpression of the Met/HGF receptor in ovarian cancer. Int J Cancer 1994; 58: 658-662.
    • (1994) Int. J. Cancer , vol.58 , pp. 658-662
    • Di Renzo, M.F.1
  • 24
    • 0029082188 scopus 로고
    • Hepatocyte growth factor and its receptor (c-met) in prostatic carcinoma
    • Humphrey PA et al. Hepatocyte growth factor and its receptor (c-met) in prostatic carcinoma. Am J Pathol 1995; 147: 386-396.
    • (1995) Am. J. Pathol. , vol.147 , pp. 386-396
    • Humphrey, P.A.1
  • 25
    • 0028979240 scopus 로고
    • C-met proto-oncogene expression in benign and malignant human prostate tissues
    • Pisters LL et al. C-met proto-oncogene expression in benign and malignant human prostate tissues. J Urol 1995; 154: 293-298.
    • (1995) J. Urol. , vol.154 , pp. 293-298
    • Pisters, L.L.1
  • 26
    • 0026441272 scopus 로고
    • Overexpression of the c-met/HGF receptor gene in human thyroid carcinomas
    • Di Renzo MF et al. Overexpression of the c-met/HGF receptor gene in human thyroid carcinomas. Oncogene 1992; 7: 2549-2553.
    • (1992) Oncogene , vol.7 , pp. 2549-2553
    • Di Renzo, M.F.1
  • 27
    • 0031939323 scopus 로고    scopus 로고
    • Expression of the hepatocyte growth factor and c-met in normal thyroid, non-neoplastic, and neoplastic nodules
    • Trovato M et al. Expression of the hepatocyte growth factor and c-met in normal thyroid, non-neoplastic, and neoplastic nodules. Thyroid 1998; 8: 125-131.
    • (1998) Thyroid , vol.8 , pp. 125-131
    • Trovato, M.1
  • 28
    • 0028941747 scopus 로고
    • Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer
    • Di Renzo MF et al. Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer. Cancer Res 1995; 55: 1129-1138.
    • (1995) Cancer Res. , vol.55 , pp. 1129-1138
    • Di Renzo, M.F.1
  • 29
    • 0028946604 scopus 로고
    • Overexpression and amplification of the Met/HGF receptor gene during the progression of colorectal cancer
    • Di Renzo ME et al. Overexpression and amplification of the Met/HGF receptor gene during the progression of colorectal cancer. Clin Cancer Res 1995; 1: 147-154.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 147-154
    • Di Renzo, M.E.1
  • 30
    • 0030277558 scopus 로고    scopus 로고
    • Participation of c-met in the progression of human gastric cancers: Anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells
    • Kaji M et al. Participation of c-met in the progression of human gastric cancers: anti-c-met oligonucleotides inhibit proliferation or invasiveness of gastric cancer cells. Cancer Gene Ther 1996; 3: 393-404.
    • (1996) Cancer Gene Ther. , vol.3 , pp. 393-404
    • Kaji, M.1
  • 31
    • 0033135820 scopus 로고    scopus 로고
    • The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas
    • Nakajima M et al. The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer 1999; 85: 1894-1902.
    • (1999) Cancer , vol.85 , pp. 1894-1902
    • Nakajima, M.1
  • 32
    • 0030690583 scopus 로고    scopus 로고
    • Met and hepatocyte growth factor/scatter factor expression in human gliomas
    • Koochekpour S et al. Met and hepatocyte growth factor/scatter factor expression in human gliomas. Cancer Res 1997; 57: 5391-5398.
    • (1997) Cancer Res. , vol.57 , pp. 5391-5398
    • Koochekpour, S.1
  • 33
    • 0035159240 scopus 로고    scopus 로고
    • MET receptor is overexpressed but not mutated in oral squamous cell carcinomas
    • Morello S et al. MET receptor is overexpressed but not mutated in oral squamous cell carcinomas. J Cell Physiol 2001; 189: 285-290.
    • (2001) J. Cell Physiol. , vol.189 , pp. 285-290
    • Morello, S.1
  • 34
    • 0029803612 scopus 로고    scopus 로고
    • Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance
    • Ichimura E, Maeshima A, Nakajima T, Nakamura T. Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance. Jpn J Cancer Res 1996; 87: 1063-1069.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 1063-1069
    • Ichimura, E.1    Maeshima, A.2    Nakajima, T.3    Nakamura, T.4
  • 35
    • 0027380637 scopus 로고
    • Hepatocyte growth factor may act as a pumotropic factor on lung regeneration after acute lung injury
    • Yanagita K et al. Hepatocyte growth factor may act as a pumotropic factor on lung regeneration after acute lung injury. J Biol Chem 1993; 269: 21212-21217.
    • (1993) J. Biol. Chem. , vol.269 , pp. 21212-21217
    • Yanagita, K.1
  • 36
    • 0031854558 scopus 로고    scopus 로고
    • The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers
    • (Review)
    • To CT, Tsao MS. The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review). Oncol Rep 1998; 5: 1013-1024.
    • (1998) Oncol. Rep. , vol.5 , pp. 1013-1024
    • To, C.T.1    Tsao, M.S.2
  • 37
    • 0036221263 scopus 로고    scopus 로고
    • Dysregulation of met receptor tyrosine kinase activity in invasive tumors
    • Danilkovitch-Miagkova A, Zbar B. Dysregulation of met receptor tyrosine kinase activity in invasive tumors. J Clin Invest 2002; 109: 863-867.
    • (2002) J. Clin. Invest. , vol.109 , pp. 863-867
    • Danilkovitch-Miagkova, A.1    Zbar, B.2
  • 38
    • 0031912249 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasis
    • Terada T, Nakanuma Y, Sirica AE. Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasis. Hum Pathol 1998; 29: 75-80.
    • (1998) Hum. Pathol. , vol.29 , pp. 75-80
    • Terada, T.1    Nakanuma, Y.2    Sirica, A.E.3
  • 39
    • 0034789096 scopus 로고    scopus 로고
    • Overexpression of the c-met protooncogene in human gastric carcinoma - Correlation to clinical features
    • Huang TJ et al. Overexpression of the c-met protooncogene in human gastric carcinoma - correlation to clinical features. Acta Oncol 2001; 40: 638-643.
    • (2001) Acta Oncol. , vol.40 , pp. 638-643
    • Huang, T.J.1
  • 40
    • 0037081204 scopus 로고    scopus 로고
    • Met protein expression level correlates with survival in patients with late-stage nasopharyngeal carcinoma
    • Qian CN et al. Met protein expression level correlates with survival in patients with late-stage nasopharyngeal carcinoma. Cancer Res 2002; 62: 589-596.
    • (2002) Cancer Res. , vol.62 , pp. 589-596
    • Qian, C.N.1
  • 41
    • 0028353491 scopus 로고
    • Immunoreactive HGF is a strong and independent predictor of recurrence and survival in human breast cancer
    • Yamashita J et al. Immunoreactive HGF is a strong and independent predictor of recurrence and survival in human breast cancer. Cancer Res 1994; 54: 1630-1633.
    • (1994) Cancer Res. , vol.54 , pp. 1630-1633
    • Yamashita, J.1
  • 42
    • 0031057905 scopus 로고    scopus 로고
    • Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer
    • Siegfried JM et al. Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer. Cancer Res 1997; 57: 433-439.
    • (1997) Cancer Res. , vol.57 , pp. 433-439
    • Siegfried, J.M.1
  • 43
    • 0030458008 scopus 로고    scopus 로고
    • Immunoreactivity for hepatocyte growth factor and its receptor, met, in human lung carcinomas and malignant mesotholioma
    • Harvey P et al. Immunoreactivity for hepatocyte growth factor and its receptor, met, in human lung carcinomas and malignant mesotholioma. J Pathol 1996; 180: 389-394.
    • (1996) J. Pathol. , vol.180 , pp. 389-394
    • Harvey, P.1
  • 44
    • 0029790384 scopus 로고    scopus 로고
    • Hepatocyte growth factor and c-Met/hepatocyte growth factor receptor in pulmonary adenocarcinomas: An evaluation of their expression as prognostic markers
    • Takanami I et al. Hepatocyte growth factor and c-Met/hepatocyte growth factor receptor in pulmonary adenocarcinomas: an evaluation of their expression as prognostic markers. Oncology 1996; 53: 392-397.
    • (1996) Oncology , vol.53 , pp. 392-397
    • Takanami, I.1
  • 45
    • 0028108731 scopus 로고
    • In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation
    • Noonberg SB et al. In vivo generation of highly abundant sequence-specific oligonucleotides for antisense and triplex gene regulation. Nucleic Acids Res 1994; 22: 2830-2836.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2830-2836
    • Noonberg, S.B.1
  • 46
    • 0027080432 scopus 로고
    • Stable transfection of human malignant melanoma cells with basic fibroblast growth factor antisense cDNA
    • Noonberg SB, Rodeck U, Weinmann R, Herlyn M. Stable transfection of human malignant melanoma cells with basic fibroblast growth factor antisense cDNA. Ann NY Acad Sci 1992; 660: 293-294.
    • (1992) Ann. NY Acad. Sci. , vol.660 , pp. 293-294
    • Noonberg, S.B.1    Rodeck, U.2    Weinmann, R.3    Herlyn, M.4
  • 47
    • 0032724509 scopus 로고    scopus 로고
    • Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer
    • Siegfried JM et al. Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer. Pulm Pharmacol Ther 1999; 12: 291-302.
    • (1999) Pulm. Pharmacol. Ther. , vol.12 , pp. 291-302
    • Siegfried, J.M.1
  • 48
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 49
    • 0026094167 scopus 로고
    • A novel cationic liposome reagent for efficient transfection of mammalian cells
    • Gao X, Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem Biophys Res Commun 1991; 179: 280-285.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 280-285
    • Gao, X.1    Huang, L.2
  • 50
    • 0030766214 scopus 로고    scopus 로고
    • Growth inhibition of human papillomavirus 16 DNA-positive mouse tumor by antisense RNA transcribed from U6 promoter
    • He Y, Huang L. Growth inhibition of human papillomavirus 16 DNA-positive mouse tumor by antisense RNA transcribed from U6 promoter. Cancer Res 1997; 57: 3993-3999.
    • (1997) Cancer Res. , vol.57 , pp. 3993-3999
    • He, Y.1    Huang, L.2
  • 51
    • 0032528051 scopus 로고    scopus 로고
    • Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter
    • He Y et al. Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst 1998; 90: 1080-1087.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 1080-1087
    • He, Y.1
  • 52
    • 0025159442 scopus 로고
    • Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts
    • Sauterer RA, Goyal A, Zieve GW. Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts. J Biol Chem 1990; 265: 1048-1058.
    • (1990) J. Biol. Chem. , vol.265 , pp. 1048-1058
    • Sauterer, R.A.1    Goyal, A.2    Zieve, G.W.3
  • 53
    • 0028835479 scopus 로고
    • Stimulatory effects of hepatocyte growth factor on normal and neoplastic human bronchial epithelial cells
    • Singh-Kaw P, Zarnegar R, Siegfried JM. Stimulatory effects of hepatocyte growth factor on normal and neoplastic human bronchial epithelial cells. Am J Physiol 1995; 268: L1012-L1020.
    • (1995) Am. J. Physiol. , vol.268
    • Singh-Kaw, P.1    Zarnegar, R.2    Siegfried, J.M.3
  • 54
    • 0024465085 scopus 로고
    • Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box
    • Kunkel GR, Pederson T. Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box. Nucleic Acids Res 1989; 17: 7371-7379.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7371-7379
    • Kunkel, G.R.1    Pederson, T.2
  • 55
    • 0033671412 scopus 로고    scopus 로고
    • TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo
    • Endo S et al. TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivo. Gene Ther 2000; 7: 1906-1914.
    • (2000) Gene Ther. , vol.7 , pp. 1906-1914
    • Endo, S.1
  • 56
    • 12944272024 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
    • Grandis JR et al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Natl Acad Sci USA 2000; 97: 4227-4232.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 4227-4232
    • Grandis, J.R.1
  • 57
    • 0033924663 scopus 로고    scopus 로고
    • Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis
    • Hyde SC et al. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther 2000; 7: 1156-1165.
    • (2000) Gene Ther. , vol.7 , pp. 1156-1165
    • Hyde, S.C.1
  • 58
    • 0035879090 scopus 로고    scopus 로고
    • Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: A phase I clinical trial
    • Hortobagyl GN et al. Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial. J Clin Oncol 2001; 19: 4183-4184.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 4183-4184
    • Hortobagyl, G.N.1
  • 59
    • 0036303883 scopus 로고    scopus 로고
    • A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma
    • Villaret D et al. A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma. Head Neck 2002; 24: 661-669.
    • (2002) Head Neck , vol.24 , pp. 661-669
    • Villaret, D.1
  • 60
    • 0034650543 scopus 로고    scopus 로고
    • The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urokinase plasminogen activator-plasmin proteolytic network
    • Webb CP et al. The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urokinase plasminogen activator-plasmin proteolytic network. Cancer Res 2000; 60: 342-349.
    • (2000) Cancer Res. , vol.60 , pp. 342-349
    • Webb, C.P.1
  • 61
    • 0036188465 scopus 로고    scopus 로고
    • Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer
    • Maulik G et al. Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer. Clin Cancer Res 2002; 8: 620-627.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 620-627
    • Maulik, G.1
  • 62
    • 0032832192 scopus 로고    scopus 로고
    • A peptide representing the carboxyl-terminal tail of the met receptor inhibits kinase activity and invasive growth
    • Bardelli A et al. A peptide representing the carboxyl-terminal tail of the met receptor inhibits kinase activity and invasive growth. J Biol Chem 1999; 274: 29274-29281.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29274-29281
    • Bardelli, A.1
  • 63
    • 0033568455 scopus 로고    scopus 로고
    • Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression
    • Abounader R et al. Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression. J Natl Cancer Inst 1999; 91: 1548-1556.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1548-1556
    • Abounader, R.1
  • 64
    • 0036365052 scopus 로고    scopus 로고
    • In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
    • Abounader R et al. In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. FASEB J 2002; 16: 108-110.
    • (2002) FASEB J. , vol.16 , pp. 108-110
    • Abounader, R.1
  • 65
    • 0034881625 scopus 로고    scopus 로고
    • A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-Met and reduces migration and invasiveness of breast cancer cells
    • Jiang WG et al. A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-Met and reduces migration and invasiveness of breast cancer cells. Clin Cancer Res 2001; 7: 2555-2562.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2555-2562
    • Jiang, W.G.1
  • 66
    • 0035957990 scopus 로고    scopus 로고
    • Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions
    • Atabey N et al. Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions. J Biol Chem 2001; 276: 14308-14314.
    • (2001) J. Biol. Chem. , vol.276 , pp. 14308-14314
    • Atabey, N.1
  • 67
    • 0034683667 scopus 로고    scopus 로고
    • Essential role of Gab1 for signaling by the c-Met receptor in vivo
    • Sachs M et al. Essential role of Gab1 for signaling by the c-Met receptor in vivo. J Cell Biol 2000; 150: 1375-1384.
    • (2000) J. Cell Biol. , vol.150 , pp. 1375-1384
    • Sachs, M.1
  • 68
    • 0034673786 scopus 로고    scopus 로고
    • Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis
    • Gual P et al. Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis. Oncogene 2000; 19: 1509-1518.
    • (2000) Oncogene , vol.19 , pp. 1509-1518
    • Gual, P.1
  • 69
    • 0034660080 scopus 로고    scopus 로고
    • Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src
    • Nakaigawa N, Weirich G, Schmidt L, Zbar B. Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src. Oncogene 2000; 19: 2996-3002.
    • (2000) Oncogene , vol.19 , pp. 2996-3002
    • Nakaigawa, N.1    Weirich, G.2    Schmidt, L.3    Zbar, B.4
  • 70
    • 0037173756 scopus 로고    scopus 로고
    • K252a inhibits the oncogenic properties of Met, the HGF receptor
    • Morotti A et al. K252a inhibits the oncogenic properties of Met, the HGF receptor. Oncogene 2002; 21: 4885-4893.
    • (2002) Oncogene , vol.21 , pp. 4885-4893
    • Morotti, A.1
  • 71
    • 0036122473 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 blocker delays healing of esophageal ulcers in rats and inhibits ulceration-triggered c-Met/hepatocyte growth factor receptor induction and extracellular signal-regulated kinase 2 activation
    • Baatar D et al. Selective cyclooxygenase-2 blocker delays healing of esophageal ulcers in rats and inhibits ulceration-triggered c-Met/hepatocyte growth factor receptor induction and extracellular signal-regulated kinase 2 activation. Am J Pathol 2002; 160: 963-972.
    • (2002) Am. J. Pathol. , vol.160 , pp. 963-972
    • Baatar, D.1
  • 72
    • 0035168570 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: Cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression
    • Chen JH, Liu TY, Wu CW, Chi CW. Nonsteroidal anti-inflammatory drugs for treatment of advanced gastric cancer: cyclooxygenase-2 is involved in hepatocyte growth factor mediated tumor development and progression. Med Hypothesis 2001; 57: 503-505.
    • (2001) Med. Hypothesis , vol.57 , pp. 503-505
    • Chen, J.H.1    Liu, T.Y.2    Wu, C.W.3    Chi, C.W.4
  • 73
    • 0037401065 scopus 로고    scopus 로고
    • Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells
    • Qian LW et al. Radiation stimulates HGF receptor/c-Met expression that leads to amplifying cellular response to HGF stimulation via upregulated receptor tyrosine phosphorylation and MAP kinase activity in pancreatic cancer cells. Int J Cancer 2003; 104: 542-549.
    • (2003) Int. J. Cancer , vol.104 , pp. 542-549
    • Qian, L.W.1
  • 74
    • 0033950285 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small cell lung cancer
    • Nemunaitis J et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small cell lung cancer. J Clin Oncol 2000; 18: 609-622.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 609-622
    • Nemunaitis, J.1


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