-
1
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
B. Kerem J.M. Rommens J.A. Buchanan D. Markiewicz T.K. Cox A. Chakravarti M. Buchwald L.C. Tsui Identification of the cystic fibrosis gene: Genetic analysis Science 245 1989 1073-1080
-
(1989)
Science
, vol.245
, pp. 1073-1080
-
-
Kerem, B.1
Rommens, J.M.2
Buchanan, J.A.3
Markiewicz, D.4
Cox, T.K.5
Chakravarti, A.6
Buchwald, M.7
Tsui, L.C.8
-
2
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
J.R. Riordan J.M. Rommens B. Kerem N. Alon R. Rozmahel Z. Grzelczak J. Zielenski S. Lok N. Plavsic J.L. Chou et al. Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA Science 245 1989 1066-1073
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
-
3
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for Mendelian disease, future approaches for complex disease
-
D. Botstein N. Risch Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex disease Nat Genet 33 2003 228-237
-
(2003)
Nat. Genet.
, vol.33
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
4
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
J.P. Hugot M. Chamaillard H. Zouali S. Lesage J.P. Cezard J. Belaiche S. Almer C. Tysk C.A. O'Morain M. Gassull et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 411 2001 599-603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
-
6
-
-
0037342213
-
Candidate gene case-control studies
-
A.K. Daly Candidate gene case-control studies Pharmacogenomics 4 2003 127-139
-
(2003)
Pharmacogenomics
, vol.4
, pp. 127-139
-
-
Daly, A.K.1
-
7
-
-
0035257236
-
Association study designs for complex disease
-
L.R. Cardon J.I. Bell Association study designs for complex disease Nat Rev Genet 2 2001 91-99
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 91-99
-
-
Cardon, L.R.1
Bell, J.I.2
-
8
-
-
0035988383
-
What makes a good case-control study? Design issues for complex traits such as endometriosis
-
K.T. Zondervan L.R. Cardon S.H. Kennedy What makes a good case-control study? Design issues for complex traits such as endometriosis Hum Reprod 17 2002 1415-1423
-
(2002)
Hum. Reprod.
, vol.17
, pp. 1415-1423
-
-
Zondervan, K.T.1
Cardon, L.R.2
Kennedy, S.H.3
-
9
-
-
0037082324
-
Target validation of G-protein coupled receptors
-
A. Wise K. Gearing S. Rees Target validation of G-protein coupled receptors Drug Discov Today 7 2002 235-246
-
(2002)
Drug Discov. Today
, vol.7
, pp. 235-246
-
-
Wise, A.1
Gearing, K.2
Rees, S.3
-
11
-
-
0035989032
-
Polymorphic G-protein-coupled receptors and associated diseases
-
D.M. Perez Polymorphic G-protein-coupled receptors and associated diseases Receptors Channels 8 2002 57-64
-
(2002)
Receptors Channels
, vol.8
, pp. 57-64
-
-
Perez, D.M.1
-
14
-
-
0035450481
-
Identification and functional characterisation of a2-adrenoceptor polymorphisms
-
K.M. Small S.B. Liggett Identification and functional characterisation of a2-adrenoceptor polymorphisms Trends Pharmacol Sci 22 2001 471-477
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 471-477
-
-
Small, K.M.1
Liggett, S.B.2
-
15
-
-
0036033424
-
Constitutive activity of G-protein-coupled receptors: Cause of disease and common property of wild-type receptors
-
R. Seifert K. Wenzel-Seifert Constitutive activity of G-protein-coupled receptors:cause of disease and common property of wild-type receptors Naunyn Schmiedebergs Arch Pharmacol 366 2002 381-416
-
(2002)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.366
, pp. 381-416
-
-
Seifert, R.1
Wenzel-Seifert, K.2
-
17
-
-
0036485214
-
Chemokine receptors: Multifaceted therapeutic targets
-
A.E.I. Proudfoot Chemokine receptors: Multifaceted therapeutic targets Nat Rev Immunol 2 2002 106-115
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 106-115
-
-
Proudfoot, A.E.I.1
-
18
-
-
0030018156
-
CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
-
G. Alkhatib C. Combadiere C.C. Broder Y. Feng P.E. Kennedy P.M. Murphy E.A. Berger CC CKR5: A RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1 Science 272 1996 1955-1958
-
(1996)
Science
, vol.272
, pp. 1955-1958
-
-
Alkhatib, G.1
Combadiere, C.2
Broder, C.C.3
Feng, Y.4
Kennedy, P.E.5
Murphy, P.M.6
Berger, E.A.7
-
19
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
H. Deng R. Liu W. Ellmeier S. Choe D. Unutmaz M. Burkhart P. Di Marzio S. Marmon R.E. Sutton C.M. Hill et al. Identification of a major co-receptor for primary isolates of HIV-1 Nature 381 1996 661-666
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
Choe, S.4
Unutmaz, D.5
Burkhart, M.6
Di Marzio, P.7
Marmon, S.8
Sutton, R.E.9
Hill, C.M.10
-
20
-
-
0029417004
-
Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells
-
F. Cocchi A.L. DeVico A. Garzino-Demo S.K. Arya R.C. Gallo P. Lusso Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells Science 270 1995 1811-1815
-
(1995)
Science
, vol.270
, pp. 1811-1815
-
-
Cocchi, F.1
DeVico, A.L.2
Garzino-Demo, A.3
Arya, S.K.4
Gallo, R.C.5
Lusso, P.6
-
21
-
-
0001633495
-
Genetic restriction of HIV-1 infection sand progression to AIDS by a deletion allele of the CKR5 structural gene
-
M. Dean M. Carrington C. Winkler G.A. Huttley M.W. Smith R. Allikmets J.J. Goedert S.P. Buchbinder E. Vittinghof E. Gomperts et al. Genetic restriction of HIV-1 infection sand progression to AIDS by a deletion allele of the CKR5 structural gene Science 273 1996 1856-1861
-
(1996)
Science
, vol.273
, pp. 1856-1861
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
Goedert, J.J.7
Buchbinder, S.P.8
Vittinghof, E.9
Gomperts, E.10
-
22
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
R. Liu W.A. Paxton S. Choe D. Ceradini S.R. Martin R. Horuk M.E. MacDonald H. Stuhlmann R.A. Koup N.R. Landau Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection Cell 86 1996 367-377
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
Ceradini, D.4
Martin, S.R.5
Horuk, R.6
MacDonald, M.E.7
Stuhlmann, H.8
Koup, R.A.9
Landau, N.R.10
-
23
-
-
0037133317
-
HIV's response to a CCR5 inhibitor: I'd rather tighten than switch!
-
J.M. Farber E.A. Berger HIV's response to a CCR5 inhibitor: I'd rather tighten than switch! Proc Natl Acad Sci USA 99 2002 1749-1751
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1749-1751
-
-
Farber, J.M.1
Berger, E.A.2
-
24
-
-
13344269098
-
CCR5 antagonists for the treatment of HIV
-
C.G. Barber CCR5 antagonists for the treatment of HIV Curr Opin Investig Drugs 5 2004 851-861
-
(2004)
Curr. Opin. Investig. Drugs
, vol.5
, pp. 851-861
-
-
Barber, C.G.1
-
25
-
-
16644381659
-
The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection
-
K. Maeda H. Nakata H. Ogata Y. Koh T. Miyakawa H. Mitsuya The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection Curr Opin Pharmacol 4 2004 447-452
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 447-452
-
-
Maeda, K.1
Nakata, H.2
Ogata, H.3
Koh, Y.4
Miyakawa, T.5
Mitsuya, H.6
-
26
-
-
0037039380
-
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
-
A. Trkola S.E. Kuhmann J.M. Strizki E. Maxwell T. Ketas T. Morgan P. Pugach S. Xu L. Wojcik J. Tagat et al. HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use Proc Natl Acad Sci USA 99 2002 395-400
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 395-400
-
-
Trkola, A.1
Kuhmann, S.E.2
Strizki, J.M.3
Maxwell, E.4
Ketas, T.5
Morgan, T.6
Pugach, P.7
Xu, S.8
Wojcik, L.9
Tagat, J.10
-
27
-
-
0344924846
-
Thyroid-stimulating hormone receptor and its role in Graves' disease
-
D.A. Chistiakov Thyroid-stimulating hormone receptor and its role in Graves' disease Mol Genet Metab 80 2003 377-388
-
(2003)
Mol. Genet. Metab.
, vol.80
, pp. 377-388
-
-
Chistiakov, D.A.1
-
28
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
S. Mandala R. Hajdu J. Bergstrom E. Quackenbush J. Xie J. Milligan R. Thornton G.-J. Shei D. Card C. Keohahe et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists Science 296 2002 346-349
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.-J.8
Card, D.9
Keohahe, C.10
-
29
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine-1-phosphate receptors
-
V. Brinkmann M.D. Davis C.E. Heise R. Albert S. Cottens R. Hof C. Bruns E. Prieschl T. Baumruker P. Hiestand et al. The immune modulator FTY720 targets sphingosine-1-phosphate receptors J Biol Chem 277 2002 21453-21457
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
Albert, R.4
Cottens, S.5
Hof, R.6
Bruns, C.7
Prieschl, E.8
Baumruker, T.9
Hiestand, P.10
-
30
-
-
8444225971
-
Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability
-
J.L. Huang P.S. Gao R.A. Mathias T.C. Yao L.C. Chen M.L. Kuo S.C. Hsu B. Plunkett A. Togias K.C. Barnes et al. Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability Hum Mol Genet 13 2004 2691-2697
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2691-2697
-
-
Huang, J.L.1
Gao, P.S.2
Mathias, R.A.3
Yao, T.C.4
Chen, L.C.5
Kuo, M.L.6
Hsu, S.C.7
Plunkett, B.8
Togias, A.9
Barnes, K.C.10
-
31
-
-
0033083112
-
Selective expression of a novel surface molecule by human Th2 cells in vivo
-
K. Nagata K. Tanaka K. Ogawa K. Kemmotsu T. Imai O. Yoshie H. Abe K. Tada M. Nakamura K. Sugamura et al. Selective expression of a novel surface molecule by human Th2 cells in vivo J Immunol 162 1999 1278-1286
-
(1999)
J. Immunol.
, vol.162
, pp. 1278-1286
-
-
Nagata, K.1
Tanaka, K.2
Ogawa, K.3
Kemmotsu, K.4
Imai, T.5
Yoshie, O.6
Abe, H.7
Tada, K.8
Nakamura, M.9
Sugamura, K.10
-
32
-
-
0035862329
-
Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
-
H. Hirai K. Tanaka O. Yoshie K. Ogawa K. Kenmotsu Y. Takamori M. Ichimasa K. Sugamura M. Nakamura S. Takano et al. Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2 J Exp Med 193 2001 255-261
-
(2001)
J. Exp. Med.
, vol.193
, pp. 255-261
-
-
Hirai, H.1
Tanaka, K.2
Yoshie, O.3
Ogawa, K.4
Kenmotsu, K.5
Takamori, Y.6
Ichimasa, M.7
Sugamura, K.8
Nakamura, M.9
Takano, S.10
-
33
-
-
0022557575
-
Release of prostaglandin D2 into human airways during acute antigen challenge
-
J.J. Murray A.B. Tonnel A.R. Brash L.J. Roberts II P. Gosset R. Workman A. Capron J.A. Oates Release of prostaglandin D2 into human airways during acute antigen challenge N Engl J Med 315 1986 800-804
-
(1986)
N. Engl. J. Med.
, vol.315
, pp. 800-804
-
-
Murray, J.J.1
Tonnel, A.B.2
Brash, A.R.3
Roberts II, L.J.4
Gosset, P.5
Workman, R.6
Capron, A.7
Oates, J.A.8
-
34
-
-
0032406835
-
Disorders of the calcium-sensing receptor
-
R.V. Thakker Disorders of the calcium-sensing receptor Biochim Biophys Acta 1448 1998 166-170
-
(1998)
Biochim. Biophys. Acta
, vol.1448
, pp. 166-170
-
-
Thakker, R.V.1
-
35
-
-
0035989009
-
Activating mutations of the lutropin choriogonadotropin receptor in precocious puberty
-
A. Shenker Activating mutations of the lutropin choriogonadotropin receptor in precocious puberty Receptors Channels 8 2002 3-18
-
(2002)
Receptors Channels
, vol.8
, pp. 3-18
-
-
Shenker, A.1
-
36
-
-
0035834685
-
Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis
-
R. Seifert K. Wenzel-Seifert Defective Gi protein coupling in two formyl peptide receptor mutants associated with localized juvenile periodontitis J Biol Chem 276 2001 42043-42049
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42043-42049
-
-
Seifert, R.1
Wenzel-Seifert, K.2
|