Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in Vitro

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 8, 2003, Pages 1219-1224

  Okubo, Tomoko ^a   Suzuki, Toshinari ^a   Yokoyama, Yoshiko ^b   Kano, Kazutaka ^b   Kano, Itsu ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Anti estrogen; Dicyclohexyl phthalate (DCHP); Estrogen; MCF 7; Monocyclohexyl phthalate (MCHP); Phthalate ester

Indexed keywords

ANTIESTROGEN; ESTER DERIVATIVE; ESTRADIOL; FULVESTRANT; PHTHALIC ACID DERIVATIVE; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DRUG DERIVATIVE; ESTER; ESTROGEN; GROWTH INHIBITOR; PHTHALIC ACID; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

ARTICLE; BREAST CANCER; CANCER CELL; CELL ASSAY; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION; BREAST TUMOR; CELL DIVISION; DOSE RESPONSE; DRUG EFFECT; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CELL DIVISION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTERS; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; GROWTH INHIBITORS; HUMANS; PHTHALIC ACIDS;

EID: 2142698524     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.26.1219     Document Type: Article

References (45)

1. Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological profile for di(2-ethylhexyl) phthalate U.S. Public Health Service, U.S Department of Health and Human Services, Atlanta, GA, 1993.
2. Research and Statistics Department Minister's Secretariat, "Yearbook of Chemical Industries Statistics in 1999," Ministry of International Trade and Industry, Tokyo, 2000, pp. 142-145.
3. Suzuki T , Yaguchi K , Suzuki S., Suga T., Environ Sci. Technol , 35, 3757-3763 (2001)
4. Saito I , Onuki A., Seto H., Uehara S., Fujii T., Ann. Rep Tokyo Metr Res. Lab P. H , 52, 201-207 (2001).
5. Kluwe W. M , McConnell E. E., Huff J. E., Haseman J. K., Douglas J. F , Hartwell W. V , Environ Health Perspect, 45, 129-133 (1982)
6. Diwan B. A., Ward J. M , Rice J. M , Colburn N. H., Spangler E. F., Carcinogenesis?, 6, 343-347 (1985).
7. Ward J M., Rice J. M., Creasia D., Lynch P., Riggs C., Carcinogenesis, 4, 1021-1029 (1983)
8. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 〈http//www.institutodopvc.org/english/monografia.htm〉 March 2003.
9. Poon R., Lecavalier P., Mueller R , Valli V E , Procter B. G., Chu I., Food Chem Toxicol., 35, 225-239 (1997).
10. Agarwal D. K., Maronpot R. R., Lamb J. C., 4th, Kluwe W. M., Toxicology, 35, 189-206 (1985).
11. Ema M., Miyawaki E., Kawashima K., Reprod Toxicol , 12, 127-132 (1998).
12. Ema M., Miyawaki E., Kawashima K., Reprod. Toxicol., 14, 13-19 (2000).
13. Mylchreest E., Cattley R. C , Foster P. M. D , Toxicol Sci , 43, 47-60 (1998).
14. Li L. H., Jester W. F., Jr., Orth J. M., Toxicol. Appl. Pharmacol., 153, 258-265 (1998).
15. Dalgaard M , Nellemann C., Lam H. R , Sorensen I K , Ladefoged O., Toxicol. Lett., 122, 69-79 (2001).
16. Heindel J. J., Powell C. J., Taxicol Appl. Pharmacol , 115, 116-123 (1992).
17. Gray T. J., Beamand J. A., Food Chem. Toxicol., 22, 123-131 (1984).
18. Daniel J. W., Bratt H., Toxicology, 2, 51-65 (1974).
19. Pollack G. M., Shen D. D., Dorr M. B., J. Pharmacol. Exp. Ther , 248, 176-181 (1989).
20. Peck C. C., Odom D. G., Albro P. W., Jess D. A., Barrett B. B., Transfusion, 21, 163-166 (1981).
21. Blount B. C., Silva M. J., Caudill S. P., Needham L. L., Pirkle J. L., Sampson E. J., Lucier G. W., Jackson R. J., Brock J. W., Environ. Health Perspect., 108, 979-982 (2000).
22. Soto A. M., Sonnenschein C., Chung K. L., Fernandez M. F., Olea N., Serrano F. O., Environ. Health Perspect., 103 (Suppl. 7), 113-122 (1995).
23. Harris C A., Henttu P., Parker M. G , Sumpter J. P., Environ. Health Perspect., 105, 802-811 (1997).
24. Zacharewski T. R., Meek M. D., Clemons J. H., Wu Z. F., Fielden M. R., Matthews J. B., Toxicol Sci., 46, 282-293 (1998).
25. Jobling S., Reynolds T., White R., Parker M. G., Sumpter J. P., Environ. Health Perspect., 103, 582-587 (1995).
26. Snell R. P., J. AOAC Int., 76, 531-534 (1993).
27. Okubo T., Yokoyama Y., Kano K., Kano I., Food Chem. Toxicol., 39, 1225-1232 (2001).
28. Roemer E., Tewes F. J., Meisgen T. J., Veltel D. J., Carmines E. L., Food Chem. Toxicol., 40, 105-111 (2002).
29. Wakeling A. E., Dukes M., Bowler J., Cancer Res., 51, 3867-3873 (1991)
30. Lake B. G , Foster J. R., Collins M. A , Stabberfield C. R., Gangolli S. D., Srivastava S. P , Acta Pharmacol Toxicol (Copenh), 51, 217-226 (1982).
31. Blom A., Ekman E., Johannisson A., Norrgren L., Pesonen M , Arch Environ. Contam. Toxicol , 34, 306-310 (1998).
32. Picard K., Lhuguenot J. C., Lavier-Canivenc M. C., Chagnon M. C., Toxicol. Appl. Pharmacol., 172, 108-118 (2001).
33. Nishihara T., Nishikawa J., Kanayama T., Dakeyama F., Saito K., Imagawa M., Takatori S., Kitagawa Y., Hori S., Utsumi H., J. Health Sci., 46, 282-298 (2000).
34. Coldham N. G., Dave M., Sivapathasundaram S., McDonnell D. P., Connor C., Sauer M. J., Environ Health Perspect, 105, 734-742 (1997).
35. Sohoni P., Sumpter J. P., J. Endocrinol., 158, 327-339 (1998).
36. Paganetto G., Campi F., Varani K., Piffanelli A., Giovannim G., Borea P. A., Pharmacol. Toxicol., 86, 24-29 (2000).
37. Blair R. M., Fang H., Branham W. S., Hass B. S., Dial S. L., Moland C. L., Tong W., Shi L., Perkins R., Sheehan D. M., Toxicol. Sci. 54, 138-153 (2000).
38. Villalobos M., Olea N., Bretons J. A., Olea-Serrano M. F., Ruiz de Almodovar J. M., Pedraza V., Environ. Health Perspect., 103, 844-850 (1995).
39. Ema M., Miyawaki E., Reprod. Toxicol., 15, 261-267 (2001).
40. Davis B. J., Maronpot R. R., Heindel J., Toxicol Appl. Pharmacol., 128, 216-223 (1994).
41. David R. M., Moore M. R., Cifone M. A., Finney D. C., Guest D., Toxicol. Sci., 50, 195-205 (1999)
42. David R. M., Moore M. R., Finney D. C , Guest D., Toxicol. Sci., 55, 433-443 (2000).
43. Mitchell A. M., Lhuguenot J. C., Bridges J. W., Elcombe C. R., Toxicol. Appl. Pharmacol , 80, 23-32 (1985).
44. Maloney E. K., Waxman D. J., Toxicol. Appl. Pharmacol., 161, 209-218 (1999).
45. Lovekamp T. N., Davis B. J., Toxicol. Appl. Pharmacol., 172, 217-224 (2001).