Chronic peroxisome proliferation and hepatomegaly associated with the hepatocellular tumorigenesis of Di(2-ethylhexyl)phthalate and the effects of recovery

Toxicological Sciences

Volumn 50, Issue 2, 1999, Pages 195-205

  David, Raymond M ^a   Moore, Michael R ^b   Cifone, Maria A ^b   Finney, Dean C ^c   Guest, Derek ^a  

^a EASTMAN KODAK COMPANY   (United States)

^b UK   (United States)

^c EASTMAN CHEMICAL COMPANY   (United States)

Author keywords

Cell proliferation; DEHP; Hepatocellular carcinogenesis; Peroxisome proliferation; Recovery

Indexed keywords

PALMITOYL COENZYME A; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HEPATOMEGALY; HISTOPATHOLOGY; LIVER TUMOR; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; OXIDATION; PEROXISOME; RAT; TUMOR GROWTH;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CELL DIVISION; DIETHYLHEXYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATOMEGALY; LIVER NEOPLASMS; MALE; MICE; ORGAN SIZE; OXIDATION-REDUCTION; PALMITOYL COENZYME A; PEROXISOMAL DISORDERS; PEROXISOME PROLIFERATORS; PEROXISOMES; RATS; RATS, INBRED F344; SEX FACTORS; SURVIVAL RATE; TIME FACTORS;

ANIMALIA; RODENTIA;

EID: 0032867057     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/50.2.195     Document Type: Article

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