Chemistry: Tyrosinase reactivity in a model complex: An alternative hydroxylation mechanism

Science

Volumn 308, Issue 5730, 2005, Pages 1890-1892

  Mirica, Liviu M ^a   Vance, Michael ^a   Rudd, Deanne Jackson ^a   Hedman, Britt ^b   Hodgson, Keith O ^a,b   Solomon, Edward I ^a   Stack, T Daniel P ^a  

^a STANFORD UNIVERSITY   (United States)

^b SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION SPECTROSCOPY; AROMATIC COMPOUNDS; CHEMICAL BONDS; COPPER; ENZYMES; OXIDATION; SOLUTIONS;

BOND CLEAVAGE; CATECHOLS; OXIDANTS; PHENOLATES;

COMPLEXATION;

COPPER COMPLEX; PHENOL DERIVATIVE; TYROSINE; BIS MU OXODICOPPER(III) PHENOLATE COMPLEX; BIS-MU-OXODICOPPER(III)-PHENOLATE COMPLEX; COPPER; LIGAND; MONOPHENOL MONOOXYGENASE; ORGANOMETALLIC COMPOUND; OXYGEN;

CHEMISTRY;

ABSORPTION SPECTROSCOPY; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HYDROXYLATION; PRIORITY JOURNAL; REACTION ANALYSIS; SUBSTITUTION REACTION; TEMPERATURE DEPENDENCE; BINDING SITE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; COLD; METABOLISM; OXIDATION REDUCTION REACTION; PHYSICAL CHEMISTRY;

BINDING SITES; CATALYSIS; CHEMISTRY, PHYSICAL; COLD; COPPER; HYDROXYLATION; LIGANDS; MODELS, CHEMICAL; MONOPHENOL MONOOXYGENASE; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; OXYGEN; PHENOLS;

EID: 21344458566     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1112081     Document Type: Article

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