Biochemistry and cell biology of phospholipase D in human neutrophils

Chemistry and Physics of Lipids

Volumn 80, Issue 1-2, 1996, Pages 3-19

  Olson, Susan C ^a   Lambeth, J David ^b  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diradylglycerols; Neutrophils; Phosphatidic acid; Phospholipase D; Protein kinase C; Rho monomeric GTPase

Indexed keywords

DIACYLGLYCEROL; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; PHOSPHATIDIC ACID; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PHOSPHOLIPID; PROTEIN KINASE C;

BIOCHEMISTRY; CALCIUM TRANSPORT; CYTOLOGY; ENZYME ACTIVATION; HOST RESISTANCE; HYDROLYSIS; LEUKOCYTE ACTIVATION; NEUTROPHIL; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; REVIEW; SECOND MESSENGER;

EID: 0029886953     PISSN: 00093084     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-3084(96)02541-8     Document Type: Article

References (126)

1. H.L. Malech and J.I. Gallin (1987) Current concepts: immunology neutrophils in human diseases. N. Engl. J. Med. 317, 687-694.
2. F.M. Sheridan, I.M. Dauber, I.F. McMurty, E.J. Lesnefsky and L.D. Horwitz (1991) Role of leukocytes in coronary vascular endothelial injury due to ischemia and reperfusion. Circ. Res. 69, 1566-1574.
3. J.D. Lambeth (1994) Receptor-regulated phospholipases and their generation of lipid mediators which activate protein kinase C, in: J.F. Kuo (Ed.), Protein Kinase C, Oxford University Press, New York, pp. 121-170.
4. Z. Kiss and W.B. Anderson (1989) Phorbol ester stimulates the hydrolysis of phosphatidylethanolamine in leukemic HL-60, NIH-3T3, and baby hamster cells. J. Biol. Chem. 264, 1483-1487.
5. W. R. Bishop and R.M. Bell (1986) Attenuation of sn-1,2-diacylglycerol second messengers: metabolism of exogenous diacylglycerols by human platelets. J. Biol. Chem. 261, 12513-12519.
6. M. Heller (1978) Phospholipase D. Adv. Lipid Res. 16, 267-326.
7. 2 activity specific for phosphatidic acid: a possible mechanism for the production of arachidonic acid in platelets. J. Biol. Chem. 256, 5399-5403.
8. W.H. Moolenaar, W. Kruijer, B.C. Tilly, I. Verlaan, A.J. Bierman and S.W. deLast (1986) Growth factor-like action of phosphatidic acid. Nature 323, 171-173.
9. W.H. Moolenaar, R.L. van der Bend, E.J. van Corven, K. Jalink, T. Eicholtz and W.J. van Blitterswijk (1992) Lysophosphatidic acid: a novel phospholipid with hormone and growth factor-like activities. Cold Spring Harbor Symp. Quant. Biol. 57, 163-167.
10. E.J. van Corven, A. Groenink, K. Jalink, T. Eichholtz and W.H. Moolenaar (1989) Lysophosphatidate-induced cell proliferation: identification and dissection of signaling pathways mediated by G proteins. Cell 59, 45-54.
11. T.C. Knauss, F.E. Jaffer and H.E. Abboud (1990) Phosphatidic acid modulates DNA synthesis, phospholipase C and platelet-derived growth factor mRNAs in cultured mesangial cells: role of protein kinase C. J. Biol. Chem. 265, 14457-14463.
12. K. Fukami and T. Takenawa (1992) Phosphatidic acid that accumulates in platelet derived growth factor-stimulated Balb/c 3T3 cells is a potent mitogenic signal. J. Biol. Chem. 267, 10988-10993.
13. M.H. Tsai, C.L. Yu, F.S. Wei and D.W. Stacey (1988) The effect of GTPase activating protein upon Ras is inhibited by mitogenically responsive lipids. Science 243, 522-526.
14. G. M. Bokoch and C.J. Der (1993) Emerging concepts in the Ras superfamily of GTP-binding proteins. FASEB 7, 750-759.
15. R.L. van der Bend, J. Brunner, K. Jalink, E.J. van Corven, W.H. Moolenaar and W.J. van Blitterswijk (1992) Identification of a putative membrane receptor for the bioactive phospholipid, lysophosphatidic acid. EMBO J. 11, 2495-2501.
16. J.W. Putney, Jr., S.J. Weiss, C.M. van de Walle and R.A. Haddas (1980) Is phosphatidic acid a calcium ionophore under neurohumoral control? Nature 284, 345-347.
17. J.G. Altin and F.L. Bygrave (1987) Phosphatidic acid and arachidonic acid each interact synergistically with glucagon to stimulate calcium influx in the perfused rat liver. Biochem. J. 247, 613-619.
18. K. Jalink, E.J. van Corven and W.H. Moolenaar (1990) Lysophosphatidic acid is a potent calcium-mobilizing stimulus for fibroblasts: evidence for extracellular site of action. J. Biol. Chem. 265, 12232-12239.
19. D.K. Perry, V.L. Stevens, T.S. Widlanski and J.D. Lambeth (1993) A novel ecto-phosphatidic acid phosphohydrolase activity mediates activation of neutrophil superoxide generation by exogenous phosphatidic acid. J. Biol. Chem. 268, 25302-25310.
20. S. Jackowski and C.O. Rock (1989) Stimulation of phosphatidylinositol 4,5-bisphosphate phospholipase C activity by phosphatidic acid. Arch. Biochem. Biophys. 268, 516-524.
21. M.E. Dunlop and R.G. Larkins (1989) Effects of phosphatidic acid on islet cell phosphoinositidc hydrolysis, calcium and adenylate cyclase. Diabetes 38, 1187-1192.
22. A. Moritz, P.N.E. DeBraan, W.H. Gispen and K.W.A. Wirtz (1992) Phosphatidic acid is a specific activator of phosphatidylinositol-4-kinase. J. Biol. Chem. 267, 7207-7210.
23. D.E. Agwu, L.C. McPhail, S. Sozzani, D.A. Bass and C.E. McCall (1991) Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes: Effects on activation of NADPH oxidase. J. Clin. Invest. 88, 531-539.
24. S.B. Bocckino, P.B. Wilson and J.H. Exton (1991) Phosphatidate-dependent protein phosphorylation. Proc. Natl. Acad. Sci. USA 88, 6210-6213.
25. W.A. Khan, G.C. Blobe, A.L. Richards and Y.A. Hannun (1994) Identification, partial purification, and characterization of a novel phospholipid-dependent and fatty acid-activated protein kinase from human platelets. J. Biol. Chem. 269, 9729-9735.
26. M.H. Lee and R.M. Bell (1989) Phospholipid functional groups involved in protein kinase C activation, phorbol ester binding and binding to mixed micelles. J. Biol. Chem. 264, 14797-14805.
27. R.M. Epand and A.R. Stafford (1990) Counter-regulatory effects of phosphatidic acid on protein kinase C activity in the presence of calcium and diolein. Biochem. Biophys. Res. Commun. 171, 487-490.
28. Y. Sasaki, Y. Asaoka and Y. Nishizuka (1993) Potentiation of diacylglycerol-induced activation of protein kinase C by lysopholipids: subspecies difference. FEBS Lett. 320, 47-51.
29. J.K. Pai, M.I. Siegel, R.W. Egan and M.M. Billah (1988) Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes. J. Biol. Chem. 263, 12472-12477.
30. H. W. Meuller, J.T. O'Flaherty, D.G. Greene, M.P. Samuel and R.L. Wykle (1984) 1-O-Alkyl-linked glycerophospholipids of human neutrophils: distribution of arachidonate and other acyl residues in ether-linked and diacyl species. J. Lipid Res. 25, 383-388.
31. M.J. Berridge (1984) Inositol trisphosphate and diacylglycerol as second messengers. Biochem. J. 20, 345-360.
32. M.C. Cabot and S. Jaken (1984) Structural and chemical specificity of diradylglycerols for protein kinase C activation. Biochem. Biophys. Res. Commun. 125, 163-169.
33. L.W. Daniel, G.W. Small and J. Schmitt (1988) Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols, Biochim. Biophys. Res. Acta 151, 291-297.
34. D.A. Ford, R. Miyake, P.E. Glaser and R.W. Gross (1989) Activation of protein kinase C by naturally occurring ether-linked diglycerides. J. Biol. Chem. 264, 13818-13824.
35. D.J. Uhlinger, D.N. Burnham and J.D. Lambeth (1991) Nucleoside triphosphate requirements for superoxide generation and phosphorylation in a cell-free system from human neutrophils: sodium dodecyl sulfate and diacylglycerol activate independently of protein kinase C. J. Biol. Chem. 266, 20990-20997.
36. rac. Nature 351, 400-402.
37. R.M. Epand (1985) Diacylglycerols, lysolecithin or hydrocarbon markedly alter the bilayer hexagonal phase transition temperature of phosphatidylethanolamines. Biochemistry 24, 7092-7095.
38. 2 + -dependent conversion of phosphatidylethanolamine to phosphatidate in neutrophils stimulated with fmet-leu-phe or ionophore A23187. Biochim. Biophys. Acta 795, 37-46.
39. M. Saito and J.N. Kanfer (1975) Phosphatidylhydrolase activity in solubilized preparation from rat brain particulate fraction. Arch. Biochem. Biophys. 169, 318-323.
40. S.B. Bocckino, P.F. Blackmore, P.B. Wilson and J.H. Exton (1987) Phosphatidate accumulation in hormone-treated via a phospholipase D mechanism. J. Biol. Chem. 262, 15309-15315.
41. M.M. Billah (1993) Phospholipase D and cell signaling. Curr. Opin. Immunol. 5, 114-123.
42. M.M.S. Billah, S. Eckel, T.J. Mullman, R.W. Egan and M.J. Siegel (1989) Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic-peptide-stimulated human neutrophils: involvement of phosphatidate phosphohydrolase in signal transduction. J. Biol. Chem. 264, 17069-17077.
43. D.E. Agwu, L.C. McPhail, M.C. Chabot, L.W. Daniel and C.E. McCall (1989) Choline-linked phosphoglycerides: a source of phosphatidic acid and diglycerides in stimulated neutrophils. J. Biol. Chem. 264, 1405-1413.
44. M.M. Billah and J.C. Anthes (1990) The regulation and cellular function of phosphatidylcholine hydrolysis. Biochem. J. 269, 281-291.
45. J. Balsinde, E. Diez and F. Mollinedo (1988) Phosphatidylinositol-specific phospholipase D: a pathway for generation of a second messenger. Biochem. Biophys. Res. Commun. 154, 502-508.
46. J. Balsinde, E. Diez, B. Fernandez and F. Mollinedo (1989) Biochemical characterization of phospholipase D activity from human neutrophils. Eur. J. Biochem. 186, 717-724.
47. C. Wang, R.L. Wykle, L.W. Daniel and M.C. Cabot (1992) Identification of phosphatidylcholine-selective and phosphatidylinositol-selective phospholipase D in Madin-Darby Canine Kidney cells. J. Biol. Chem. 267, 16859-16865.
48. P. Wang, J.C. Anthes, M.I. Siegel, R.W. Egan and M.M. Billah (1991) Existence of cytosolic phospholipase D: identification and comparison with membrane-bound enzyme. J. Biol. Chem. 266, 14877-14880.
49. R.A. Clark (1990) The human neutrophil respiratory burst oxidase. J. Infect. Dis. 161, 1140-1147.
50. J.D. Lambeth (1988) Activation of the respiratory burst oxidase in neutrophils: on the role of membrane-derived second messengers, calcium, and protein kinase C. J. Bioenerg. Biomembr. 20, 709-733.
51. R.W. Bonser, N.T. Thompson, R.W. Randall and L.G. Garland (1989) Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil. Biochem. J. 264, 617-620.
52. S.C. Olson, S.R. Tyagi and J.D. Lambeth (1990) Fluoride activates diradylglycerol and superoxide generation in human neutrophils via PLD/PA phosphohydrolase-dependent and -independent pathways. FEBS Lett. 272, 19-24.
53. S.A. Bauldry, D.A. Bass, S.L. Cousart and C.E. McCall (1991) Tumor necrosis factor α priming of phospholipase D in human neutrophils: correlation between phosphatidic acid production and superoxide generation. J. Biol. Chem. 266, 4173-4179.
54. S.A. Bauldry, K.L. Elsey and D.A. Bass (1992) Activation of NADPH oxidase and phospholipase D in permeabilized human neutrophils: correlation between oxidase activation and phosphatidic acid production. J. Biol. Chem. 267, 25141-25152.
55. F. Rossi, M. Grzeskowiak, V. Della-Bianca, F. Calzetti and G. Gandini (1990) Phosphatidic acid and not diacylglycerol generated by phospholipase D is functionally linked to the activation of the NADPH oxidase by fMLP in human neutrophils. Biochem. Biophys. Res. Commun. 168, 320-327.
56. D.K. Perry, W.L. Hand, D.E. Edmondson and J.D. Lambeth (1992) Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. J. Immunol. 149, 2749-2758.
57. 2 and lactoferrin release in adherent human neutrophils. J. Biol. Chem. 269, 8063-8068.
58. M. Fallman, M. Gullberg, C. Hellberg and T. Anderson (1992) Complement receptor-mediated phagocytosis is associated with accumulation of phosphatidylcholine-derived diglyceride in human neutrophils: involvement of phospholipase D and direct evidence for a positive feedback signal of protein kinase C. J. Biol. Chem. 267, 2656-2663.
59. H. R. Dohlman, J. Thorner, M.G. Caron and R.J. Lefkowitz (1991) Model systems for the study of seven-transmembrane segment receptors. Annu. Rev. Biochem. 60, 653-688.
60. C. Gerard and N.P. Gerard (1994) C5a Anaphylatoxin and its seven transmembrane segment receptor. Annu. Rev. Immunol. 12, 775-808.
61. i-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells. J. Biol. Chem. 21470-21473.
62. D. English, G. Taylor and J.G.N. Garcia (1991) Diacylglycerol generation in fluoride-treated neutrophils: involvement of phospholipase D. Blood 77, 2746-2756.
63. T.M. Wright, L.A. Rangan, H.S. Shin and D.M. Raben (1988) Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts: comparison of stimulation by α-thrombin and epidermal growth factor. J. Biol. Chem. 263, 9374-9380.
64. P. Ben-Av and M. Liscovitch (1989) Phospholipase D activation by the mitogens platelet-derived growth factor and 12-O-tetradecanoylphorbol 13-acetate in NIH-3T3 cells. FEBS Lett. 259, 64-66.
65. R. Plevin, S.J. Cook, S. Palmer and M.J.O. Wakelam (1991) Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Biochem. J. 279, 559-565.
66. A. Ahmed, R. Plevin, M.A. Shoaibi, S.A. Fountain, R.A. Ferriani and S.K. Smith (1994) Basic FGF activates phopholipase D in endothelial cells in the absence of inositol lipid hydrolysis. Am. J. Physiol. 266, C06-12.
67. M. Raszkin, L. Seidler, R. Kast and K. Volker (1992) Epidermal-growth-factor-induced production of phosphatidylalcohols by HeLa cells and A431 cells through activation of phospolipase D. Biochem. J. 287, 51-57.
68. Y.H. Lee, H.S. Kim, J.-K. Pai, S.H. Ryu and P.-G. Suh (1994) Activation of phospholipase D induced by platelet-derived growth factor is dependent upon the level of phospholipase Cγ1. J. Biol. Chem. 269, 26842-26847.
69. E.-J. Yeo, A. Kazlauskas and J. H. Exton (1994) Activation of phospholipase C-γ is necessary for stimulation of phospholipase D by platelet-derived growth factor. J. Biol. Chem. 269, 27823-27826.
70. E.-J. Yeo and J.H. Exton (1995) Stimulation of phospholipase D by epidermal growth factor requires protein kinase C activation in Swiss 3T3 cells. J. Biol. Chem. 270, 3980-3988.
71. H. Jiang, L. Zhimin, J.-Q. Luo, A. Wolfman and D.A. Foster (1995) Ras mediates the activation of phospholipase D by v-Src. J. Biol. Chem. 270, 6006-6009.
72. S. Bourgoin and S. Grinstein (1992) Peroxides of vanadate induce activation of phospholipase D in HL-60 cells: role of tyrosine phosphorylation. J. Biol. Chem. 267, 11908-11916.
73. I.J. Uings, N.T. Thompson, R.W. Randall, G.D. Spacey, R.W. Bonser, A.T. Hudson and L.G. Garland (1992) Tyrosine phosphorylation is involved in receptor coupling to phospholipase D but not phospholipase C in human neutrophil. Biochem. J. 281, 597-600.
74. D.J. Kusner, S.J. Schomisch and G.R. Dubyak (1993) ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes. J. Biol. Chem. 268, 19973-19982.
75. G. R. Dubyak, S. J. Schomisch, D.J. Kusner and M. Xie (1993) Phospholipase D activity in phagocytic leucocytes is synergistically regulated by G-protein and tyrosine kinase-based mechanisms. Biochemistry 292, 121-128.
76. A.E. Traynor-Kaplan, B.L. Thompson, A.L. Harris, P. Taylor, G. Omann and L.A. Sklar (1989) Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils. J. Biol. Chem. 264, 15668-15673.
77. S.S. Singh, A. Chauhan, H. Brockerhoff and V.P. Chauhan (1993) Activation of protein kinase C by phosphatidylinositol 3,4,5 trisphosphate. Biochem. Biophys. Res. Commun. 195, 104-112.
78. H. Nakanishi, K.A. Brewer and J.H. Exton (1993) Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5 trisphosphate. J. Biol. Chem. 268, 13-16.
79. A. Arcaro and M.P. Wymann (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem. J. 296, 297-301.
80. T. Okada, L. Sakuma, Y. Fukui, O. Hazeki, and M. Ui (1994) Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J. Biol. Chem. 269, 3563-3567.
81. S.L. Reinhold, S.M. Prescott, G.A. Zimmerman and T.M. McIntyre (1990) Activation of human neutrophil phospholipase D by three separable mechanisms. FASEB J. 4, 208-214.
82. M. Liscovitch (1989) Phosphatidylethanolamine biosynthesis in ethanol-exposed NG108-15 neuroblastoma X glioma hybrid cells: evidence for activation of a phospholipase D phosphatidyl transferase activity by protein kinase C. J. Biol. Chem. 264, 1450-1456.
83. W.J. van Blitterswijk, H. Hilkmann, J. de Widt and R.L. van der Bend (1991) Phospholipid metabolism in bradykinin-stimulated human fibroblasts. II. Phosphatidylcholine breakdown by phospholipases C and D; involvement of protein kinase C. J. Biol. Chem. 266, 10344-10350.
84. S.J. Cook, C.P. Briscoe and M. Wakelam (1991) The regulation of phospholipase D activity and its role in sn-1,2-diradylglycerol formation in bombesin- and phorbol 12-myristate 13-acetate-stimulated Swiss 3T3 cells. Biochem. J. 280, 431-438.
85. T.W. Martin, D.R. Feldman, K.C. Michaelis (1990) Phosphatidylcholine hydrolysis stimulated by phorbol myristate acetate is mediated principally by phospholipase D in endothelial cells. Biochim. Biophys. Acta 1053, 162-172.
86. J. Horwitz and S. Ricanatik (1992) Bradykinin and phorbol dibutyrate activate phospholipase D in PC12 cells by different mechanisms. J. Neurochem. 59, 1474-1480,
87. S.L. Reinhold, S.M. Prescott, G.A. Zimmerman and T.M. McIntyre (1990) Activation of human neutrophil phospholipase D by three separate mechanisms. FASEB J. 4, 208-214.
88. M.M. Billah, J.K. Pai, T.J. Mullman, R.W. Egan and M.I. Siegel (1989) Regulation of phospholipase D in HL-60 granulocytes, activation by phorbol esters, diglyceride, and calcium ionophore via protein kinase C-independent mechanisms. J. Biol. Chem. 264, 9069-9076.
89. Y. Cao, C.C. Reddy and A.M. Mastro (1990) Evidence for a protein kinase C independent activation of phospholipase D by phorbol esters in lymphocytes. Biochem. Biophys. Res. Commun. 171, 955-962.
90. K. Yamada Y. Kanaho, K. Miura and Y. Nozawa (1991) Antigen-induced phospholipase D activation in mast cells is independent of protein kinase C. Biochem. Biophys. Res. Commun. 175, 159-164.
91. G.C. Kessels, D. Roos and A.J. Verhoeven (1991) FMet-Leu-Phe-induced activation of phospholipase D in human neutrophils: dependence on changes in cytosolic free calcium concentrations and relation with respiratory burst activation. J. Biol. Chem. 266, 23152-23156.
92. S.C. Olson, E.P. Bowman and J.D. Lambeth (1991) Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5′-O-(3-thiotriphosphate): activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol. J. Biol. Chem. 266, 17236-17242.
93. J.K. Pai, M.I. Siefel, R.W. Egan and M.M. Billah (1988) Activation of phospholipase D by chemotactic peptide in HL-60 granulocytes. J. Biol. Chem. 263, 12472-12477.
94. 2 +, protein kinase C, and protein kinase A in hormonal stimulation of phospholipase D in rat hepatocytes. J. Biol. Chem. 269, 849-859.
95. M. Liscovitch and Y. Eli (1991) Calcium inhibits guanine nucleotide-activated phospholipase D in neural-derived NG108-15 cells. Cell Regul. 2, 1011-1019.
96. 2 +. Biochem. J. 224, 629-635.
97. J-E. Lehmeyer and R.B. Johnson, Jr. (1978) Effect of anti-inflammatory drugs and agents that elevate intracellular cyclic AMP on the release of toxic oxygen metabolites by phagocytes. Clin. Immunol. Immunopathol. 9, 482-490.
98. S.R. Tyagi, S.C. Olson, D.N. Burnham and J.D. Lambeth (1991) Cyclic AMP-elevating agents block chemoattractant activation of diradylglycerol generation by inhibiting phospholipase D activation. J. Biol. Chem. 266, 3498-3504.
99. D.E. Agwu, C.E. McCall and L.C. McPhail (1991) Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils. J. Immunol. 146, 3895-3903.
100. J.G. Garcia, J.W. Fenton and V. Natarajan (1992) Thrombin stimulation of human endothelial cell phospholipase D activity. Regulation by phospholipase C, protein kinase C and cyclic adenosine 3′5′-monophosphate. Blood 79, 2056-2067.
101. P.A. Stevens, S. Pyne, M. Grady and N.J. Pyne (1994) Bradykinin-dependent activation of adenylate cyclase activity and cyclic AMP accumulation in tracheal smooth muscle occurs via protein kinase C-dependent and -independent pathways. Biochem. J. 297, 233-239.
102. Z. Qian and L.R. Drewes (1989) Muscarinic acetylcholine receptor regulates phosphatidylcholine phospholipase D in canine brain. J. Biol. Chem. 264, 21720-21724.
103. J. Van der Meulen and R.J. Haslam (1990) Phorbol ester treatment of intact rabbit platelets greatly enhances both the basal and guanosine 5′-[γ-thio]triphosphate-stimulated PLD activities in isolated plasma membranes: physiological activation of PLD may be secondary to activation of PLC. Biochem. J. 271, 693-700.
104. J.C. Anthes, C.P. Wang, M.I. Siegel, R.W. Egan and M.M. Billah (1991) Granulocyte phospholipase D is activated by a guanine nucleotide dependent protein factor. Biochem. Biophys. Res. Commun. 175, 236-243.
105. E.P. Bowman, D.J. Uhlinger and J.D. Lambeth (1993) Neutrophil phospholipase D is activated by a membrane-associated rho family small molecular weight GTP-binding protein. J. Biol. Chem. 268, 21509-21512.
106. S. Kuroda, A. Kikuchi and Y. Takai (1989) Racl, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties. Biochem. Biophys. Res. Commun. 163, 674-681.
107. R.A. Kahn (1991) Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins. J. Biol. Chem. 266, 15595-15597.
108. T. Mizuno, K. Kaibuchi, T. Yamamoto, M. Kawamura, T. Sakoda, H. Fujioka, Y. Matsuura and Y. Takai (1991) A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. Proc. Natl. Acad. Sci. USA 88, 6442-6446.
109. K. Hiraoka, K. Kaibuchi, S. Ando, T. Musha, K. Takaishi, T. Mizuno, M. Asada, L. Menard, E. Tomhave, E. Didsbury, R. Snyderman and Y. Takai (1992) Both stimulatory and inhibitory GDP/GTP exchange proteins, smg GDS and rho GDI are active on multiple small GTP-binding proteins. Biochem. Biophys. Res. Commun. 182, 921-930.
110. K.C. Malcolm, A.H. Ross, R.-G. Qui, M. Symons and J.H. Exton (1994) Activation of rat liver phospholipase D by the small GTP-binding protein rhoA. J. Biol. Chem. 269, 25951-25954.
111. H. Brown, S. Gutowski, S.R. Moomaw, C. Slaughter and P.C. Sternweis (1993) ADP-ribosylation factor, a small GTP-binding regulatory protein stimulates phospholipase D activity. Cell 75, 1137-1144.
112. S. Cockcroft, G.M.H. Thomas, A. Fensome, B. Geny, E. Cunningham, I. Gout, I. Hiles, N.F. Totty, O. Truong and J.J. Hsuan (1994) Phospholipase D: a downstream effector of ARF in granulocytes. Science 263, 523-526.
113. D. Massenburg, J.-S. Han, M. Liynage, W.A. Patton, S.O. Rhee, J. Moss and M. Vaughan (1994). Activation of rat brain phospholipase D by ADP-ribosylation factors 1, 5, and 6: separation of ADP-ribosylation factor-dependent and oleate-dependent enzymes. Proc. Natl. Acad. Sci. USA 91, 11718-11722.
114. G.F. Zhang, W.A. Patton, F.-J. Lee, M. Liyanage, J.-S. Han, S.G. Rhee, J. Moss and M. Vaughan (1995) Different ARF domains are required for the activation of cholera toxin and phospholipase D. J. Biol. Chem. 270, 21-24.
115. J.D. Lambeth, J.-Y. Kwak, E.P. Bowman, D. Perry, D.J. Uhlinger and I. Lopez (1995) ADP-ribosylation factor functions synergistically with a 50-kDa cytosolic factor in cell-free activation of human neutrophil phospholipase D. J. Biol. Chem. 270, 1-4 (in press).
116. S. Bourgoin, D. Harbour, Y. Desmarais, Y. Takai and A. Beaulieu (1995) Low molecular weight GTP-binding proteins in HL-60 granulocytes: assessment of the role of ARF and of a 50 kDa cytosolic protein in phospholipase D activation. J. Biol. Chem. 270, 3172-3178.
117. I. Lopez, D.J. Burns and J.D. Lambeth (1995) Regulation of phospholipase D by protein kinase C in human neutrophils: conventional isoforms of protein kinase C phosphorylate a phospholipase D-related component in the plasma membrane. J. Biol. Chem. (submitted for publication).
118. K.M. Conricode, K.A. Brewer and J.H. Exton (1992) Activation of phospholipase D by protein kinase C: evidence for a phosphorylation independent mechanism. J. Biol. Chem. 267, 7199-7202.
119. Y. Nishizuka (1992) Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614.
120. H. Eldar, H. Ben-Av, U.S. Schmidt, E. Livneh and M. Liscovitch (1993) Up-regulation of phospholipase D activity induced by overexpression of protein kinase C-α. Studies in intact Swiss 3T3 cells and detergent-solubilized membranes in vitro. J. Biol. Chem. 268, 12560-12564.
121. M.A. Balboa, B.L. Firestein, C. Godsen, K.S. Bell and P.A. Insel (1994) Protein kinase C-α mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby Canine Kidney cells. J. Biol. Chem. 269, 10511-10516.
122. J.K. Pai, J.A. Pachter, I.B. Weinstein and W.R. Bishop (1991) Overexpression of protein kinase C-β enhances phospholipase D activity and diacylglycerol formation in phorbol ester-stimulated rat fibroblasts. Proc. Natl. Acad. Sci. USA 88, 598-602.
123. D. Mangoura and G. Dawson (1993) Opioid peptides activate phospholipase D and protein kinase C-∈ in chick embryo neuron cultures. Proc. Natl. Acad. Sci. USA 90, 2915-2919.
124. J. Pfeilschifter and A. Huwiler (1993) A role for protein kinase C-∈ in angiotensin II stimulation of phospholipase D in rat renal mesangial cells. FEBS Lett 331, 267-271.
125. M. Mckinnon and P.J. Parker (1994) Phospholipase D activation can be negatively regulated through the action of protein kinase C. Biochim. Biophys. Acta 1222, 109-112.
126. S. Pontremoli, E. Melloni, B. Sparatore, M. Michetti, F. Salamino and B.E. Horecker. (1990) Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases. J. Biol. Chem. 265, 706-712.