Pancratistatin: A natural anti-cancer compound that targets mitochondria specifically in cancer cells to induce apoptosis

Apoptosis

Volumn 10, Issue 3, 2005, Pages 619-630

  McLachlan, A ^a   Kekre, N ^a   McNulty, J ^b   Pandey, S ^a  

^a UNIVERSITY OF WINDSOR   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Anti cancer drugs; Apoptosis; Mitochondrial membrane permeability; Natural compounds; Pancratistatin

Indexed keywords

ANTINEOPLASTIC ALKALOID; ETOPOSIDE; PACLITAXEL; PANCRATISTATIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HYMENOCALIS; MEDICINAL PLANT; MITOCHONDRION; PRIORITY JOURNAL;

AMARYLLIDACEAE ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASES; CELLS, CULTURED; ETOPOSIDE; FIBROBLASTS; HUMANS; INTRACELLULAR MEMBRANES; ISOQUINOLINES; MITOCHONDRIA; NEUROBLASTOMA; PACLITAXEL; PERMEABILITY; PROTEASOME ENDOPEPTIDASE COMPLEX; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

ARANEAE; LILIUM; PANCRATIUM LITTORALE;

EID: 21244484687     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10495-005-1896-x     Document Type: Article

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