A novel mitochondrial C1-tetrahydrofolate synthetase is upregulated in human colon adenocarcinoma

Biochemical and Biophysical Research Communications

Volumn 315, Issue 1, 2004, Pages 204-211

  Sugiura, Takeyuki ^a   Nagano, Yuki ^a   Inoue, Tatsuya ^a   Hirotani, Kenji ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

C1 tetrahydrofolate synthetase; Colon cancer; Microarray; Mitochondria; One carbon unit pathway

Indexed keywords

COMPLEMENTARY DNA; DIHYDROFOLATE REDUCTASE; MITOCHONDRIAL ENZYME; FORMATE TETRAHYDROFOLATE LIGASE; FORMYL METHENYL METHYLENETETRAHYDROFOLATE SYNTHETASE; FORMYL-METHENYL-METHYLENETETRAHYDROFOLATE SYNTHETASE; HYDROLASE; METHYLENETETRAHYDROFOLATE DEHYDROGENASE; MULTIENZYME COMPLEX; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER GROWTH; CANCER TISSUE; COLON CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC DATABASE; HUMAN; HUMAN TISSUE; MITOCHONDRION; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TARGET CELL; UPREGULATION; ADENOCARCINOMA; AMINO ACID SEQUENCE; BIOSYNTHESIS; CELL DIVISION; CELL LINE; CHEMISTRY; COLON TUMOR; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

ADENOCARCINOMA; AMINO ACID SEQUENCE; AMINOHYDROLASES; CELL DIVISION; CELL LINE; CLONING, MOLECULAR; COLONIC NEOPLASMS; DNA, COMPLEMENTARY; FORMATE-TETRAHYDROFOLATE LIGASE; GENE EXPRESSION PROFILING; HUMANS; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP); MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; UP-REGULATION;

EID: 0842286542     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.01.035     Document Type: Article

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