Glucokinase: Old enzyme, new target

Expert Opinion on Therapeutic Patents

Volumn 15, Issue 6, 2005, Pages 705-713

  Kietzmann, Thomas ^a   Ganjam, Goutham Kumar ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

cell; Glucokinase; Glucokinase activator; Hepatocyte; Insulin; MODY 2; Pancreas

Indexed keywords

1 ISOPROPYL 6 METHYL 1H INDOLE 3 CARBOXYLIC ACID THIAZOL 2 YLAMIDE; 2 [3,5 BIS(2 CHLOROBENZYLOXY)BENZOYLAMINO]THIAZOLE; 2 AMINO 5 (4 METHYL 4H[1,2,4]TRIAZOL 3 YLSULFANYL) N (4 METHYLTHIAZOL 2 YL)BENZAMIDE; 2 AMINOBENZAMIDE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 [(3 ISOPROPOXY 5 [2 (3 THIENYL)ETHOXY]BENZOYL)AMINO] 1,3,4 THIADIAZOLE 2 CARBOXYLIC ACID; 6 [(3 ISOBUTOXY 5 ISOPROPOXYBENZOYL)AMINO]NICOTINIC ACID; ACETAMIDE DERIVATIVE; AMIDE; ANILIDE; ANTIDIABETIC AGENT; BENZAMIDE DERIVATIVE; BENZENE DERIVATIVE; ENZYME ACTIVATOR; GLUCOKINASE; GLUCOKINASE ACTIVATOR; GLUCOSE; HYDANTOIN DERIVATIVE; N THIAZOL 2 YL 2 AMINO 4 FLUORO 5 [1 METHYLIMIDAZOL 2 YL]THIOBENZAMIDE; NICOTINIC ACID; RO 28 0450; RO 28 1675; THIOBENZAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

CRYSTAL STRUCTURE; DISEASE MODEL; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; GLUCOSE UTILIZATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; NEWBORN DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA OF INFANCY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; QUALITY OF LIFE; REGULATORY MECHANISM; REVIEW; SENSOR; SIGNAL TRANSDUCTION;

EID: 21244470348     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.15.6.705     Document Type: Review

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