-
1
-
-
0030067124
-
A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
Matschinsky FM: A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 45:223-241, 1996
-
(1996)
Diabetes
, vol.45
, pp. 223-241
-
-
Matschinsky, F.M.1
-
2
-
-
0022467904
-
Pancreatic islet glucose metabolism and regulation of insulin secretion
-
Meglasson MD, Matschinsky FM: Pancreatic islet glucose metabolism and regulation of insulin secretion. Diabetes Metab Rev 2:163-214, 1986
-
(1986)
Diabetes Metab Rev
, vol.2
, pp. 163-214
-
-
Meglasson, M.D.1
Matschinsky, F.M.2
-
3
-
-
0026562918
-
Nonsense mutations in the glucokinase gene cause early-onset non-insulin-dependent diabetes mellitus
-
Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell GI, Zouali H, Lesage S, Velho G, Iris F, Passa P, Froguel P, Cohen D: Nonsense mutations in the glucokinase gene cause early-onset non-insulin-dependent diabetes mellitus. Nature 356:721-722, 1992
-
(1992)
Nature
, vol.356
, pp. 721-722
-
-
Vionnet, N.1
Stoffel, M.2
Takeda, J.3
Yasuda, K.4
Bell, G.I.5
Zouali, H.6
Lesage, S.7
Velho, G.8
Iris, F.9
Passa, P.10
Froguel, P.11
Cohen, D.12
-
4
-
-
0026639928
-
Human glucokinase gene: Isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus
-
Stoffel M, Froguel P, Takeda J, Zouali H, Vionnet N, Nishi S, Weber IT, Harrisson RW, Pilkis SJ, Lesage S, Vaxillaire M, Velho G, Sun F, Iris F, Passa P, Cohen D, Bell GI: Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus. Proc Natl Acad Sci U S A 89:7698-7702, 1992
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 7698-7702
-
-
Stoffel, M.1
Froguel, P.2
Takeda, J.3
Zouali, H.4
Vionnet, N.5
Nishi, S.6
Weber, I.T.7
Harrisson, R.W.8
Pilkis, S.J.9
Lesage, S.10
Vaxillaire, M.11
Velho, G.12
Sun, F.13
Iris, F.14
Passa, P.15
Cohen, D.16
Bell, G.I.17
-
5
-
-
0029986387
-
Glucokinase mutations, insulin secretion, and diabetes mellitus
-
Bell GI, Pilkis SJ, Weber IT, Polonsky KS: Glucokinase mutations, insulin secretion, and diabetes mellitus. Annu Rev Physiol 58:171-186, 1996
-
(1996)
Annu Rev Physiol
, vol.58
, pp. 171-186
-
-
Bell, G.I.1
Pilkis, S.J.2
Weber, I.T.3
Polonsky, K.S.4
-
6
-
-
0029155957
-
Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene
-
Bali D, Svetlanov A, Lee HW, Fusco-DeMane D, Leiser M, Li B, Barzilai N, Surana M, Hou H, Fleischer N, DePinho R, Rossetti L, Efrat S: Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene. J Biol Chem 270:21464-21467, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 21464-21467
-
-
Bali, D.1
Svetlanov, A.2
Lee, H.W.3
Fusco-DeMane, D.4
Leiser, M.5
Li, B.6
Barzilai, N.7
Surana, M.8
Hou, H.9
Fleischer, N.10
DePinho, R.11
Rossetti, L.12
Efrat, S.13
-
7
-
-
0028826361
-
Transgenic knockouts reveal a critical requirement for pancreatic β-cell glucokinase in maintaining glucose homeostasis
-
Grupe A, Hultgren B, Ryan A, Ma YH, Bauer M, Stewart TA: Transgenic knockouts reveal a critical requirement for pancreatic β-cell glucokinase in maintaining glucose homeostasis. Cell 83:69-78, 1995
-
(1995)
Cell
, vol.83
, pp. 69-78
-
-
Grupe, A.1
Hultgren, B.2
Ryan, A.3
Ma, Y.H.4
Bauer, M.5
Stewart, T.A.6
-
8
-
-
0032556969
-
Familial hyperinsulinism caused by an activating glucokinase mutation
-
Glaser B, Kesavan P, Heyman M, Davis E, Cuesta A, Buchs A, Stanley CA, Thornton PS, Permutt MA, Matschinsky FM, Herold KC: Familial hyperinsulinism caused by an activating glucokinase mutation. N Engl J Med 338:226-230, 1998
-
(1998)
N Engl J Med
, vol.338
, pp. 226-230
-
-
Glaser, B.1
Kesavan, P.2
Heyman, M.3
Davis, E.4
Cuesta, A.5
Buchs, A.6
Stanley, C.A.7
Thornton, P.S.8
Permutt, M.A.9
Matschinsky, F.M.10
Herold, K.C.11
-
9
-
-
0027457131
-
Glucokinase and candidate genes for type 2 (non-insulin-dependent) diabetes mellitus
-
Randle PJ: Glucokinase and candidate genes for type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 36:269-275, 1993
-
(1993)
Diabetologia
, vol.36
, pp. 269-275
-
-
Randle, P.J.1
-
10
-
-
0027186032
-
Mammalian glucokinase and its gene
-
Iynedjian PB: Mammalian glucokinase and its gene. Biochem J 293:1-13, 1993
-
(1993)
Biochem J
, vol.293
, pp. 1-13
-
-
Iynedjian, P.B.1
-
11
-
-
0028338590
-
Short-term control of glucokinase activity: Role of a regulatory protein
-
Van Schaftingen E, Detheux M, Veiga-da-Cunha M: Short-term control of glucokinase activity: role of a regulatory protein. FASEB J 8:414-419, 1994
-
(1994)
FASEB J
, vol.8
, pp. 414-419
-
-
Van Schaftingen, E.1
Detheux, M.2
Veiga-Da-Cunha, M.3
-
12
-
-
0025781602
-
Competitive inhibition of liver glucokinase by its regulatory protein
-
Vandercammen A, Van Schaftingen E: Competitive inhibition of liver glucokinase by its regulatory protein. Eur J Biochem 200:545-551, 1991
-
(1991)
Eur J Biochem
, vol.200
, pp. 545-551
-
-
Vandercammen, A.1
Van Schaftingen, E.2
-
13
-
-
0027165769
-
Species and tissue distribution of the regulatory protein of glucokinase
-
Vandercammen A, Van Schaftingen E: Species and tissue distribution of the regulatory protein of glucokinase. Biochem J 294:551-556, 1993
-
(1993)
Biochem J
, vol.294
, pp. 551-556
-
-
Vandercammen, A.1
Van Schaftingen, E.2
-
15
-
-
0029918678
-
Amino acid conservation in animal glucokinases: Identification of the residues implicated in the interaction with the regulatory protein
-
Veiga-da-Cunha M, Courtois S, Michel A, Gosselain E, Van Schaftingen E: Amino acid conservation in animal glucokinases: identification of the residues implicated in the interaction with the regulatory protein. J Biol Chem 271:6292-6297, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 6292-6297
-
-
Veiga-Da-Cunha, M.1
Courtois, S.2
Michel, A.3
Gosselain, E.4
Van Schaftingen, E.5
-
16
-
-
0342526544
-
Molecular model of human β-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B
-
St Charles R, Harrison RW, Bell GI, Pilkis SJ, Weber IT: Molecular model of human β-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B. Diabetes 43:784-791, 1994
-
(1994)
Diabetes
, vol.43
, pp. 784-791
-
-
St Charles, R.1
Harrison, R.W.2
Bell, G.I.3
Pilkis, S.J.4
Weber, I.T.5
-
17
-
-
0029766214
-
Effect of mutations on the sensitivity of human β-cell glucokinase to liver regulatory protein
-
Veiga-da-Cunha M, Xu LZ, Lee YH, Marotta D, Pilkis SJ, Van Schaftingen E: Effect of mutations on the sensitivity of human β-cell glucokinase to liver regulatory protein. Diabetologia 39:1173-1179, 1996
-
(1996)
Diabetologia
, vol.39
, pp. 1173-1179
-
-
Veiga-Da-Cunha, M.1
Xu, L.Z.2
Lee, Y.H.3
Marotta, D.4
Pilkis, S.J.5
Van Schaftingen, E.6
-
18
-
-
0025341608
-
The mechanism by which rat liver glucokinase is inhibited by the regulatory protein
-
Vandercammen A, Van Schaftingen E: The mechanism by which rat liver glucokinase is inhibited by the regulatory protein. Eur J Biochem 191:483-489, 1990
-
(1990)
Eur J Biochem
, vol.191
, pp. 483-489
-
-
Vandercammen, A.1
Van Schaftingen, E.2
-
19
-
-
0023042283
-
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
-
Studier FW, Moffatt BA: Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J Mol Biol 189:113-130, 1986
-
(1986)
J Mol Biol
, vol.189
, pp. 113-130
-
-
Studier, F.W.1
Moffatt, B.A.2
-
20
-
-
0020479806
-
Specific inhibition of glucokinase by long-chain acyl coenzyme As below the critical micelle concentration
-
Tippett PS, Neet KE: Specific inhibition of glucokinase by long-chain acyl coenzyme As below the critical micelle concentration. J Biol Chem 257:12830-12845, 1982
-
(1982)
J Biol Chem
, vol.257
, pp. 12830-12845
-
-
Tippett, P.S.1
Neet, K.E.2
-
21
-
-
77049143386
-
The determination of enzyme inhibitor constants
-
Dixon M: The determination of enzyme inhibitor constants. Biochem J 55:170-171, 1953
-
(1953)
Biochem J
, vol.55
, pp. 170-171
-
-
Dixon, M.1
-
22
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
23
-
-
0029653395
-
Human β-cell glucokinase: Dual role of Ser-151 in catalysis and hexose affinity
-
Xu LZ, Harrison RW, Weber IT, Pilkis SJ: Human β-cell glucokinase: dual role of Ser-151 in catalysis and hexose affinity. J Biol Chem 270:9939-9946, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 9939-9946
-
-
Xu, L.Z.1
Harrison, R.W.2
Weber, I.T.3
Pilkis, S.J.4
-
24
-
-
0031050536
-
Structural instability of mutant β-cell glucokinase: Implications for the molecular pathogenesis of maturity-onset diabetes of the young (type 2)
-
Kesavan P, Wang L, Davis E, Cuesta A, Sweet I, Niswender K, Magnuson MA, Malschinsky FM: Structural instability of mutant β-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type 2). Biochem J 322:57-63, 1997
-
(1997)
Biochem J
, vol.322
, pp. 57-63
-
-
Kesavan, P.1
Wang, L.2
Davis, E.3
Cuesta, A.4
Sweet, I.5
Niswender, K.6
Magnuson, M.A.7
Malschinsky, F.M.8
-
25
-
-
0014054253
-
Characterization of isoenzymes of adenosine triphosphate: D-hexose-6-phosphotransferases from rat liver
-
Gonzalez C, Ureta T, Babul J, Rabajille E, Niemeyer H: Characterization of isoenzymes of adenosine triphosphate: D-hexose-6-phosphotransferases from rat liver. Biochemistry 6:460-468, 1967
-
(1967)
Biochemistry
, vol.6
, pp. 460-468
-
-
Gonzalez, C.1
Ureta, T.2
Babul, J.3
Rabajille, E.4
Niemeyer, H.5
-
26
-
-
0002433874
-
Inhibition of glucose phosphorylation by mannoheptulose
-
Coore HG, Randle PJ: Inhibition of glucose phosphorylation by mannoheptulose. Biochem J 91:56-59, 1964
-
(1964)
Biochem J
, vol.91
, pp. 56-59
-
-
Coore, H.G.1
Randle, P.J.2
-
27
-
-
0014694681
-
The inhibition of rat liver glucokinase by palmitoyl-CoA
-
Dawson CM, Hales CN: The inhibition of rat liver glucokinase by palmitoyl-CoA. Biochem Biophys Acta 176:657-659, 1969
-
(1969)
Biochem Biophys Acta
, vol.176
, pp. 657-659
-
-
Dawson, C.M.1
Hales, C.N.2
-
29
-
-
0029886531
-
Functional organization of mammalian hexokinases: Both N- and C-terminal halves of the rat type II isozyme possess catalytic sites
-
Tsai HJ, Wilson JE: Functional organization of mammalian hexokinases: both N- and C-terminal halves of the rat type II isozyme possess catalytic sites. Arch Biochem Biophys 329:17-23, 1996
-
(1996)
Arch Biochem Biophys
, vol.329
, pp. 17-23
-
-
Tsai, H.J.1
Wilson, J.E.2
-
30
-
-
0032544488
-
Regulation of hexokinase 1: Crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate
-
Aleshin AE, Zeng C, Bartunik HD, Fromm HJ, Honzatko RB: Regulation of hexokinase 1: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate. J Mol Biol 282:345-357, 1998
-
(1998)
J Mol Biol
, vol.282
, pp. 345-357
-
-
Aleshin, A.E.1
Zeng, C.2
Bartunik, H.D.3
Fromm, H.J.4
Honzatko, R.B.5
-
31
-
-
0032518372
-
The mechanism of regulation of hexokinase: New insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate
-
Aleshin AE, Zeng C, Bourenkov GP, Bartunik HD, Fromm HJ, Honzatko RB: The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate. Structure 6:39-50, 1998
-
(1998)
Structure
, vol.6
, pp. 39-50
-
-
Aleshin, A.E.1
Zeng, C.2
Bourenkov, G.P.3
Bartunik, H.D.4
Fromm, H.J.5
Honzatko, R.B.6
-
32
-
-
0016636347
-
Studies on the mechanism of orthophosphate regulation of bovine brain hexokinase
-
Ellison WR, Lueck JD, Fromm HJ: Studies on the mechanism of orthophosphate regulation of bovine brain hexokinase. J Biol Chem 250:1864-1871, 1975
-
(1975)
J Biol Chem
, vol.250
, pp. 1864-1871
-
-
Ellison, W.R.1
Lueck, J.D.2
Fromm, H.J.3
-
33
-
-
0027970547
-
Site-directed mutagenesis studies on the determinants of sugar specificity and cooperative behavior of human β-cell glucokinase
-
Xu LZ, Zhang W, Weber IT, Harrison RW, Pilkis SJ: Site-directed mutagenesis studies on the determinants of sugar specificity and cooperative behavior of human β-cell glucokinase. J Biol Chem 269:27458-27465, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 27458-27465
-
-
Xu, L.Z.1
Zhang, W.2
Weber, I.T.3
Harrison, R.W.4
Pilkis, S.J.5
-
34
-
-
0018139955
-
A refined model of the sugar-binding site of yeast hexokinase B
-
Anderson CM, Stenkamp RE, McDonald RC, Steitz TA: A refined model of the sugar-binding site of yeast hexokinase B. J Mol Biol 123:207-219, 1978
-
(1978)
J Mol Biol
, vol.123
, pp. 207-219
-
-
Anderson, C.M.1
Stenkamp, R.E.2
McDonald, R.C.3
Steitz, T.A.4
-
35
-
-
0031016101
-
Investigation on the mechanism by which fructose, hexitols, and other compounds regulate the translocation of glucokinase in rat hepatocytes
-
Niculescu L, Veiga-da-Cunha M, Van Schaftingen E: Investigation on the mechanism by which fructose, hexitols, and other compounds regulate the translocation of glucokinase in rat hepatocytes. Biochem J 321:239-246, 1997
-
(1997)
Biochem J
, vol.321
, pp. 239-246
-
-
Niculescu, L.1
Veiga-Da-Cunha, M.2
Van Schaftingen, E.3
-
36
-
-
0027410865
-
Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: Implications for structure/function relationships
-
Gidh-Jain M, Takeda J, Xu LZ, Lange AJ, Vionnet N, Stoffel M, Froguel P, Velho G, Sun F, Cohen D, Patel P, Lo YMD, Hattersley AT, Luthman H, Wedell A, St. Charles R, Harrison RW, Weber IT, Bell GI, Pilkis SJ: Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships. Proc Natl Acad Sci U S A 90:1932-1936, 1993
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1932-1936
-
-
Gidh-Jain, M.1
Takeda, J.2
Xu, L.Z.3
Lange, A.J.4
Vionnet, N.5
Stoffel, M.6
Froguel, P.7
Velho, G.8
Sun, F.9
Cohen, D.10
Patel, P.11
Lo, Y.M.D.12
Hattersley, A.T.13
Luthman, H.14
Wedell, A.15
St. Charles, R.16
Harrison, R.W.17
Weber, I.T.18
Bell, G.I.19
Pilkis, S.J.20
more..
-
37
-
-
0013912554
-
Purification and properties of adenosine 5′-triphosphate-D-glucose-6-phosphotransferase from rat liver
-
Parry MJ, Walker DG: Purification and properties of adenosine 5′-triphosphate-D-glucose-6-phosphotransferase from rat liver. Biochem J 99:266-274, 1966
-
(1966)
Biochem J
, vol.99
, pp. 266-274
-
-
Parry, M.J.1
Walker, D.G.2
-
38
-
-
0017091068
-
Kinetics of rat liver glucokinase: Cooperative interactions with glucose at physiologically significant concentrations
-
Storer AC, Cornish-Bowden A: Kinetics of rat liver glucokinase: cooperative interactions with glucose at physiologically significant concentrations. Biochem J 159:7-14, 1976
-
(1976)
Biochem J
, vol.159
, pp. 7-14
-
-
Storer, A.C.1
Cornish-Bowden, A.2
-
39
-
-
0018093213
-
Maintenance of the monomeric structure of glucokinase under reacting conditions
-
Cardenas ML, Rabajille E, Niemeyer H: Maintenance of the monomeric structure of glucokinase under reacting conditions. Arch Biochem Biophys 190:142-148, 1978
-
(1978)
Arch Biochem Biophys
, vol.190
, pp. 142-148
-
-
Cardenas, M.L.1
Rabajille, E.2
Niemeyer, H.3
-
40
-
-
78651189765
-
On the nature of allosteric interactions: A plausible model
-
Monod J, Wyman J, Changeux JP: On the nature of allosteric interactions: a plausible model. J Mol Biol 12:88-118, 1965
-
(1965)
J Mol Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
41
-
-
0013863816
-
Comparison of experimental binding data and theoretical models in proteins containing subunits
-
Koshland DE, Némethy G, Filmer D: Comparison of experimental binding data and theoretical models in proteins containing subunits. Biochemistry 5:365-385, 1966
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland, D.E.1
Némethy, G.2
Filmer, D.3
-
42
-
-
0013863538
-
The interpretation of non-hyperbolic rate curves for two-substrate enzymes: A possible mechanism for phosphofructokinase
-
Ferdinand W: The interpretation of non-hyperbolic rate curves for two-substrate enzymes: a possible mechanism for phosphofructokinase. Biochem J 98:278-283, 1966
-
(1966)
Biochem J
, vol.98
, pp. 278-283
-
-
Ferdinand, W.1
-
43
-
-
0022966285
-
Mechanistic origin of the sigmoidal rate behaviour of rat liver hexokinase D ("glucokinase")
-
Cornish-Bowden A, Storer AC: Mechanistic origin of the sigmoidal rate behaviour of rat liver hexokinase D ("glucokinase"). Biochem J 240:293-296, 1986
-
(1986)
Biochem J
, vol.240
, pp. 293-296
-
-
Cornish-Bowden, A.1
Storer, A.C.2
-
44
-
-
0021676977
-
Suppression of kinetic cooperativity of hexokinase D (glucokinase) by competitive inhibitors: A slow transition model
-
Cardenas ML, Rabajille E, Niemeyer H: Suppression of kinetic cooperativity of hexokinase D (glucokinase) by competitive inhibitors: a slow transition model. Eur J Biochem 145:163-171, 1984
-
(1984)
Eur J Biochem
, vol.145
, pp. 163-171
-
-
Cardenas, M.L.1
Rabajille, E.2
Niemeyer, H.3
-
45
-
-
0020479821
-
An allosteric model for the inhibition of glucokinase by long-chain acyl coenzyme A
-
Tippett PS, Neet KE: An allosteric model for the inhibition of glucokinase by long-chain acyl coenzyme A. J Biol Chem 257:12846-12852, 1982
-
(1982)
J Biol Chem
, vol.257
, pp. 12846-12852
-
-
Tippett, P.S.1
Neet, K.E.2
|