-
1
-
-
0029057703
-
Human carbonic anhydrases and carbonic anhydrase deficiencies
-
Sly WS, Hu PY. Human carbonic anhydrases and carbonic anhydrase deficiencies. Annu Rev Biochem 1995; 64: 375-401
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 375-401
-
-
Sly, W.S.1
Hu, P.Y.2
-
2
-
-
0027153461
-
Expression of MaTu-MN protein in human tumor cultures and in clinical specimens
-
Zavada J, Zavadova Z, Pastorekova S, Ciampor F, Pastorek J, Zelnik V. Expression of MaTu-MN protein in human tumor cultures and in clinical specimens. Int J Cancer 2003; 54: 268-274
-
(2003)
Int. J. Cancer
, vol.54
, pp. 268-274
-
-
Zavada, J.1
Zavadova, Z.2
Pastorekova, S.3
Ciampor, F.4
Pastorek, J.5
Zelnik, V.6
-
3
-
-
0028111173
-
Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
-
Pastorek J, Pastorekova. S, Callebaut I, Mornon JP, Zelnik V, Opavsky R, Zatovicova M, Liao S, Portetelle D, Stanbridge EJ, Zavada J, Burny A, Kettmann R. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 1994; 9: 2788-2888
-
(1994)
Oncogene
, vol.9
, pp. 2788-2888
-
-
Pastorek, J.1
Pastorekova, S.2
Callebaut, I.3
Mornon, J.P.4
Zelnik, V.5
Opavsky, R.6
Zatovicova, M.7
Liao, S.8
Portetelle, D.9
Stanbridge, E.J.10
Zavada, J.11
Burny, A.12
Kettmann, R.13
-
4
-
-
0029975564
-
Human MN/CA9 gene, a novel member of the carbonic anhydrase family: Structure and exon to protein domain relationship
-
Opavsky R, Pastorekova S, Zelnik V, Gibadulinova A, Stanbridge EJ, Zavada J, Kettmann R, Pastorek J. Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationship. Genomics 1996; 33: 480-487
-
(1996)
Genomics
, vol.33
, pp. 480-487
-
-
Opavsky, R.1
Pastorekova, S.2
Zelnik, V.3
Gibadulinova, A.4
Stanbridge, E.J.5
Zavada, J.6
Kettmann, R.7
Pastorek, J.8
-
5
-
-
0041062296
-
Human carbonic anhydrase XII: cDNA cloning, expression and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cancers
-
Tüireci O, Sahin U, Vollmar E, Siemer S, Göttert E, Seitz G, Parkkila AK, Shah GN, Grubb JH, Pfreundschuh M, Sly WS. Human carbonic anhydrase XII: cDNA cloning, expression and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cancers. Proc Natl Acad Sci USA 1998; 95: 7608-7613
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7608-7613
-
-
Tüireci, O.1
Sahin, U.2
Vollmar, E.3
Siemer, S.4
Göttert, E.5
Seitz, G.6
Parkkila, A.K.7
Shah, G.N.8
Grubb, J.H.9
Pfreundschuh, M.10
Sly, W.S.11
-
6
-
-
0032514685
-
Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes
-
Ivanov SV, Kuzmin I, Wie MH, Pack S, Geil L, Johnson BE, Stanbridge EJ, Lerman MI. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc Natl Acad Sci USA 1998; 95: 12596-12601
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12596-12601
-
-
Ivanov, S.V.1
Kuzmin, I.2
Wie, M.H.3
Pack, S.4
Geil, L.5
Johnson, B.E.6
Stanbridge, E.J.7
Lerman, M.I.8
-
7
-
-
0031819881
-
Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation
-
Saarnio J, Parkkila S, Parkkila AK, Haukipuro K, Pastorekova S, Pastorek J, Kairaluoma MI, Karttunen TJ. Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation. Am J Pathol 1998; 153: 279-285
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 279-285
-
-
Saarnio, J.1
Parkkila, S.2
Parkkila, A.K.3
Haukipuro, K.4
Pastorekova, S.5
Pastorek, J.6
Kairaluoma, M.I.7
Karttunen, T.J.8
-
8
-
-
0033902802
-
Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors
-
Kivelä A, Parkkila S, Saarnio J, Karttunen TJ, Kivelä J, Parkkila AK, Waheed A, Sly WS, Grubb JH, Shah G, Türeci Ö, Rajaniemi H. Expression of a novel transmembrane carbonic anhydrase isozyme XII in normal human gut and colorectal tumors. Am J Pathol 2000; 156: 577-584
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 577-584
-
-
Kivelä, A.1
Parkkila, S.2
Saarnio, J.3
Karttunen, T.J.4
Kivelä, J.5
Parkkila, A.K.6
Waheed, A.7
Sly, W.S.8
Grubb, J.H.9
Shah, G.10
Türeci, Ö.11
Rajaniemi, H.12
-
9
-
-
0034009497
-
Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro
-
Parkkila S, Rajaniemi H, Parkkila AK, Kivelä J, Waheed A, Pastorekova S, Pastorek J, Sly WS. Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro. Proc Natl Acad Sci USA 2000; 97: 2220-2224
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2220-2224
-
-
Parkkila, S.1
Rajaniemi, H.2
Parkkila, A.K.3
Kivelä, J.4
Waheed, A.5
Pastorekova, S.6
Pastorek, J.7
Sly, W.S.8
-
10
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
Svastova E, Hulikova A, Rafajova M, Zatovicova M, Gibadulinova A, Casini A, Cecchi A, Scozzafava A, Supuran CT, Pastorek J, Pastorekova S. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett 2004; 577: 439-445
-
(2004)
FEBS Lett.
, vol.577
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zatovicova, M.4
Gibadulinova, A.5
Casini, A.6
Cecchi, A.7
Scozzafava, A.8
Supuran, C.T.9
Pastorek, J.10
Pastorekova, S.11
-
11
-
-
0033818044
-
Carbonic anhydrase inhibitors - Part 94. 1,2,4-Thiadiazole-2-sulfonamide derivatives as antitumor agents?
-
Supuran CT, Scozzafava A. Carbonic anhydrase inhibitors - Part 94. 1,2,4-Thiadiazole-2-sulfonamide derivatives as antitumor agents? Eur J Med Chem 2000; 35: 867-874
-
(2000)
Eur. J. Med. Chem.
, vol.35
, pp. 867-874
-
-
Supuran, C.T.1
Scozzafava, A.2
-
12
-
-
0037315480
-
Indisulam: An anticancer sulfonamide in clinical development
-
Supuran CT. Indisulam: an anticancer sulfonamide in clinical development. Expert Opin Investig Drugs 2003; 12: 283-287
-
(2003)
Expert Opin. Investig. Drugs
, vol.12
, pp. 283-287
-
-
Supuran, C.T.1
-
13
-
-
0142121458
-
Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with b-catenin
-
Svastova E, Zilka N, Zatovicova M, Gibadulinova A, Ciampor F, Pastorek J, Pastorekova S. Carbonic anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via interaction with b-catenin. Exp Cell Res 2003; 290: 332-345
-
(2003)
Exp. Cell Res.
, vol.290
, pp. 332-345
-
-
Svastova, E.1
Zilka, N.2
Zatovicova, M.3
Gibadulinova, A.4
Ciampor, F.5
Pastorek, J.6
Pastorekova, S.7
-
14
-
-
0034671307
-
Hypoxia inducible regulation of tumor associated carbonic anhydrases
-
Wykoff CC, Beasley NJP, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. Hypoxia inducible regulation of tumor associated carbonic anhydrases. Cancer Res 2000; 60: 7075-7083
-
(2000)
Cancer Res.
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.P.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
Wilson, G.D.7
Turley, H.8
Talks, K.L.9
Maxwell, P.H.10
Pugh, C.W.11
Ratcliffe, P.J.12
Harris, A.L.13
-
15
-
-
0042847064
-
Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer
-
Potter CPS, Harris AL. Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer. Br J Cancer 2003; 89: 2-7
-
(2003)
Br. J. Cancer
, vol.89
, pp. 2-7
-
-
Potter, C.P.S.1
Harris, A.L.2
-
16
-
-
0035105565
-
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
-
Wykoff CC, Beasley N, Watson PH, Campo L, Chia SK, English R, Pastorek J, Sly WS, Ratcliffe P, Harris AL. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol 2001; 158: 1011-1019
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 1011-1019
-
-
Wykoff, C.C.1
Beasley, N.2
Watson, P.H.3
Campo, L.4
Chia, S.K.5
English, R.6
Pastorek, J.7
Sly, W.S.8
Ratcliffe, P.9
Harris, A.L.10
-
17
-
-
0035107383
-
Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer
-
Ivanov S, Liao SY, Ivanova A, Danilkovich-Miagkova A, Tarasova N, Weirich G, Merrill MJ, Proescholdt MA, Oldfield EH, Lee J, Zavada J, Waheed A, Sly W, Lerman MI, Stanbridge EJ. Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. Am J Pathol 2001; 158: 905-919
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 905-919
-
-
Ivanov, S.1
Liao, S.Y.2
Ivanova, A.3
Danilkovich-Miagkova, A.4
Tarasova, N.5
Weirich, G.6
Merrill, M.J.7
Proescholdt, M.A.8
Oldfield, E.H.9
Lee, J.10
Zavada, J.11
Waheed, A.12
Sly, W.13
Lerman, M.I.14
Stanbridge, E.J.15
-
18
-
-
0037692904
-
Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma
-
Watson PH, Chia SK, Wykoff CC, Han C, Leek RD, Sly WS, Gatter KC, Ratcliffe P, Harris AL. Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. Br J Cancer 2003; 88: 1065-1070
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1065-1070
-
-
Watson, P.H.1
Chia, S.K.2
Wykoff, C.C.3
Han, C.4
Leek, R.D.5
Sly, W.S.6
Gatter, K.C.7
Ratcliffe, P.8
Harris, A.L.9
-
19
-
-
4544388351
-
Cancer-related carbonic anhydrase isozymes and their inhibition
-
Supuran CT, Scozzafava A, Conway J, eds. CRC Press Boca Raton London New York Washington DC
-
Pastorekova S, Pastorek J. Cancer-related carbonic anhydrase isozymes and their inhibition. In: Supuran CT, Scozzafava A, Conway J, eds. Carbonic Anhydrase, its Inhibitors and Activators. CRC Press Boca Raton London New York Washington DC 2004: 253-272
-
(2004)
Carbonic Anhydrase, Its Inhibitors and Activators
, pp. 253-272
-
-
Pastorekova, S.1
Pastorek, J.2
-
20
-
-
0033051828
-
The von Hippel-Lindau tumour suppressor protein: New perspectives
-
Ohh M, Kaelin WG Jr. the von Hippel-Lindau tumour suppressor protein: new perspectives. Mol Med Today 1999; 5: 257-263
-
(1999)
Mol. Med. Today
, vol.5
, pp. 257-263
-
-
Ohh, M.1
Kaelin Jr., W.G.2
-
21
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nature Rev Cancer 2003; 3: 721-732
-
(2003)
Nature Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
22
-
-
0036718539
-
Molecular Basis of the VHL hereditary cancer syndrome
-
Kaelin WG Jr. Molecular Basis of the VHL hereditary cancer syndrome. Nature Rev Cancer 2002; 2: 673-682
-
(2002)
Nature Rev. Cancer
, vol.2
, pp. 673-682
-
-
Kaelin Jr., W.G.1
-
23
-
-
0035795336
-
VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells
-
Karumanchi SA, Jiang L, Knebelmann B, Stuart-Tilley AK, Alper SL, Sukhatme VP. VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells. Physiol Genomics 2001; 5: 119-128
-
(2001)
Physiol. Genomics
, vol.5
, pp. 119-128
-
-
Karumanchi, S.A.1
Jiang, L.2
Knebelmann, B.3
Stuart-Tilley, A.K.4
Alper, S.L.5
Sukhatme, V.P.6
-
24
-
-
0035930581
-
A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers
-
Sterling D, Reithmeier RA, Casey JR. A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers. J Biol Chem 2001; 276: 47886-47894
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47886-47894
-
-
Sterling, D.1
Reithmeier, R.A.2
Casey, J.R.3
-
25
-
-
0037067718
-
The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV
-
Sterling D, Alvarez BV, Casey JR. The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV. J Biol Chem 2002; 277: 25239-25246
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25239-25246
-
-
Sterling, D.1
Alvarez, B.V.2
Casey, J.R.3
-
26
-
-
0030835515
-
Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney
-
Liao SY, Aurelio ON, Jan K, Zavada J, Stanbridge EJ. Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Res 1997; 57: 2827-2831
-
(1997)
Cancer Res.
, vol.57
, pp. 2827-2831
-
-
Liao, S.Y.1
Aurelio, O.N.2
Jan, K.3
Zavada, J.4
Stanbridge, E.J.5
-
27
-
-
0030984803
-
Expression of the tumour-associated gene MN: A potential biomarker for human renal cell carcinoma
-
McKiernan JM, Buttyan R, Bander NH, Stifelman MD, Katz AE, Olsson CA, Sawczuk IS. Expression of the tumour-associated gene MN: a potential biomarker for human renal cell carcinoma. Cancer Res 1997; 57: 2362-2365
-
(1997)
Cancer Res.
, vol.57
, pp. 2362-2365
-
-
McKiernan, J.M.1
Buttyan, R.2
Bander, N.H.3
Stifelman, M.D.4
Katz, A.E.5
Olsson, C.A.6
Sawczuk, I.S.7
-
28
-
-
0033637648
-
Expression of the membrane-associated carbonic anhydrase isozyme XII in the human kidney and renal tumors
-
Parkkila S, Parkkila AK, Saarnio J, Kivelä J, Karttunen TJ, Kaunisto K, Waheed A, Sly WS, Türeci Ö, Virtanen I, Rajaniemi H. Expression of the membrane-associated carbonic anhydrase isozyme XII in the human kidney and renal tumors. J Histochem Cytochem 2000; 48: 1601-1608
-
(2000)
J. Histochem. Cytochem.
, vol.48
, pp. 1601-1608
-
-
Parkkila, S.1
Parkkila, A.K.2
Saarnio, J.3
Kivelä, J.4
Karttunen, T.J.5
Kaunisto, K.6
Waheed, A.7
Sly, W.S.8
Türeci, Ö.9
Virtanen, I.10
Rajaniemi, H.11
-
29
-
-
15644384121
-
Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity
-
Saarnio J, Parkkila S, Parkkila AK, Waheed A, Casey MC, Zhou XY, Pastorekova S, Pastorek J, Karttunen T, Haukipuro K, Kairaluoma MI, Sly WS. Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity. J Histochem Cytochem 1998; 46: 497-504
-
(1998)
J. Histochem. Cytochem.
, vol.46
, pp. 497-504
-
-
Saarnio, J.1
Parkkila, S.2
Parkkila, A.K.3
Waheed, A.4
Casey, M.C.5
Zhou, X.Y.6
Pastorekova, S.7
Pastorek, J.8
Karttunen, T.9
Haukipuro, K.10
Kairaluoma, M.I.11
Sly, W.S.12
-
30
-
-
0033052893
-
Expression of von Hippel-Lindau protein in normal and pathological human tissues
-
Sakashita N, Takeya M, Kishida T, Stackhouse TM, Zbar B, Takahashi K. Expression of von Hippel-Lindau protein in normal and pathological human tissues. Histochem J 1999; 31: 133-144
-
(1999)
Histochem. J.
, vol.31
, pp. 133-144
-
-
Sakashita, N.1
Takeya, M.2
Kishida, T.3
Stackhouse, T.M.4
Zbar, B.5
Takahashi, K.6
-
31
-
-
0030025951
-
von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens
-
Zhuang Z, Emmert-Buck MR, Roth MJ, Gnarra J, Linehan WM, Liotta LA, Lubensky IA. von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens. Hum Pathol 1996; 27: 152-156
-
(1996)
Hum. Pathol.
, vol.27
, pp. 152-156
-
-
Zhuang, Z.1
Emmert-Buck, M.R.2
Roth, M.J.3
Gnarra, J.4
Linehan, W.M.5
Liotta, L.A.6
Lubensky, I.A.7
-
32
-
-
0033820175
-
The von Hippel-Lindau (VHL) tumorsuppressor gene is not mutated in sporadic human colon adenocarcinomas
-
Miyakis S, Sourvinos G, Liloglou TL, Stathopoulos GP, Field JK, Spandidos DA. The von Hippel-Lindau (VHL) tumorsuppressor gene is not mutated in sporadic human colon adenocarcinomas. Int J Cancer 2000; 88: 503-505
-
(2000)
Int. J. Cancer
, vol.88
, pp. 503-505
-
-
Miyakis, S.1
Sourvinos, G.2
Liloglou, T.L.3
Stathopoulos, G.P.4
Field, J.K.5
Spandidos, D.A.6
-
33
-
-
0026561063
-
A novel quasi-viral agent, MaTu, is a two-component system
-
Pastorekova S, Zavadova Z, Kostal M, Babusikova O, Zavada J. A novel quasi-viral agent, MaTu, is a two-component system. Virology 1992; 187: 620-626
-
(1992)
Virology
, vol.187
, pp. 620-626
-
-
Pastorekova, S.1
Zavadova, Z.2
Kostal, M.3
Babusikova, O.4
Zavada, J.5
-
34
-
-
6744255826
-
Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium
-
Karhumaa P, Parkkila S, Türeci Ö, Waheed A, Grubb JH, Shah G, Parkkila AK, Kaunisto K, Tapanainen J, Sly WS, Rajaniemi H. Identification of carbonic anhydrase XII as the membrane isozyme expressed in the normal human endometrial epithelium. Mol Hum Reprod 2000; 6: 68-74
-
(2000)
Mol. Hum. Reprod.
, vol.6
, pp. 68-74
-
-
Karhumaa, P.1
Parkkila, S.2
Türeci, Ö.3
Waheed, A.4
Grubb, J.H.5
Shah, G.6
Parkkila, A.K.7
Kaunisto, K.8
Tapanainen, J.9
Sly, W.S.10
Rajaniemi, H.11
-
35
-
-
0027770946
-
Concurrent p53 expression in bronchial dysplasias and squamous cell lung carcinomas
-
Nuorva K, Soini Y, Kamel D, Autio-Harmainen H, Risteli L, Risteli J, Vähäkangas K, Pääkkö P. Concurrent p53 expression in bronchial dysplasias and squamous cell lung carcinomas. Am J Pathol 1993; 142: 725-732
-
(1993)
Am. J. Pathol.
, vol.142
, pp. 725-732
-
-
Nuorva, K.1
Soini, Y.2
Kamel, D.3
Autio-Harmainen, H.4
Risteli, L.5
Risteli, J.6
Vähäkangas, K.7
Pääkkö, P.8
-
36
-
-
0037431557
-
Expression of hypoxia-inducible factor-1a is associated with tumor vascularization in human colorectal carcinoma
-
Kuwai T, Kitadai Y, Tanaka S, Onogawa S, Matsutani N, Kaio E, Ito M, Chayama K. Expression of hypoxia-inducible factor-1a is associated with tumor vascularization in human colorectal carcinoma. Int J Cancer 2003; 105: 176-181
-
(2003)
Int. J. Cancer
, vol.105
, pp. 176-181
-
-
Kuwai, T.1
Kitadai, Y.2
Tanaka, S.3
Onogawa, S.4
Matsutani, N.5
Kaio, E.6
Ito, M.7
Chayama, K.8
-
37
-
-
0037307858
-
The von Hippel-Lindau tumor suppressor protein: New insights into oxygen sensing and cancer
-
Kim W, Kaelin WG Jr. The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer. Current Opin Gen Dev 2003; 13: 1-6
-
(2003)
Current Opin. Gen. Dev.
, vol.13
, pp. 1-6
-
-
Kim, W.1
Kaelin Jr., W.G.2
-
38
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykof CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia inducible factors for oxygen-dependent proteolysis. Nature 1999; 399: 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykof, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
39
-
-
0035917313
-
2 sensing
-
2 sensing. Science 2001; 292: 464-468
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
40
-
-
0035917808
-
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292: 468-472
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
41
-
-
0037042183
-
Down-regulation of von-Hippel Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors
-
Shiao YH, Ramakrishna G, Anderson LM, Perantoni AO, Rice JM, Diwan BA. Down-regulation of von-Hippel Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors. Cancer Lett 2002; 179: 33-38
-
(2002)
Cancer Lett.
, vol.179
, pp. 33-38
-
-
Shiao, Y.H.1
Ramakrishna, G.2
Anderson, L.M.3
Perantoni, A.O.4
Rice, J.M.5
Diwan, B.A.6
-
42
-
-
0142187245
-
VHL down-regulation and differential localization as mechanisms in tumorigenesis
-
Shiao YH, Forsti A, Egevad L, Anderson LM, Lindblad P, Hemminki K. VHL down-regulation and differential localization as mechanisms in tumorigenesis. Kidney Int 2003; 64: 1671-1674
-
(2003)
Kidney Int.
, vol.64
, pp. 1671-1674
-
-
Shiao, Y.H.1
Forsti, A.2
Egevad, L.3
Anderson, L.M.4
Lindblad, P.5
Hemminki, K.6
-
43
-
-
2142802121
-
VHL tumor suppressor gene: Its mutation and protein level in renal cell carcinoma
-
Tsutsumi H, Miyamoto C, Furuichi Y, Yoshiike M, Nozawa S, Iwamoto T. VHL tumor suppressor gene: its mutation and protein level in renal cell carcinoma. Oncol Rep 2003; 10: 1357-1361
-
(2003)
Oncol. Rep.
, vol.10
, pp. 1357-1361
-
-
Tsutsumi, H.1
Miyamoto, C.2
Furuichi, Y.3
Yoshiike, M.4
Nozawa, S.5
Iwamoto, T.6
-
44
-
-
0033856270
-
Expression of the von Hippel-Lindau tumor suppressor gene in noneoplastic and neoplastic lesions of the thyroid
-
Hinze R, Boltze C, Meye A, Holzhausen HJ, Dralle H, Rath FW. Expression of the von Hippel-Lindau tumor suppressor gene in noneoplastic and neoplastic lesions of the thyroid. Endocr Pathol 2000; 11: 145-155
-
(2000)
Endocr. Pathol.
, vol.11
, pp. 145-155
-
-
Hinze, R.1
Boltze, C.2
Meye, A.3
Holzhausen, H.J.4
Dralle, H.5
Rath, F.W.6
-
45
-
-
0036032329
-
Effects of von Hippel-Lindau gene mutation and methylation status on expression of transmembrane carbonic anhydrases in renal cell carcinoma
-
Ashida S, Nishimori I, Tanimura M, Onishi S, Shuin T. Effects of von Hippel-Lindau gene mutation and methylation status on expression of transmembrane carbonic anhydrases in renal cell carcinoma. J Cancer Res Clin Oncol 2002; 128: 561-568
-
(2002)
J. Cancer Res. Clin. Oncol.
, vol.128
, pp. 561-568
-
-
Ashida, S.1
Nishimori, I.2
Tanimura, M.3
Onishi, S.4
Shuin, T.5
-
46
-
-
17044452288
-
HIF activation identifies early lesions in VHL kidneys: Evidence for site-specific tumor suppressor function in the nephron
-
Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell 2002; 1: 459-468
-
(2002)
Cancer Cell
, vol.1
, pp. 459-468
-
-
Mandriota, S.J.1
Turner, K.J.2
Davies, D.R.3
Murray, P.G.4
Morgan, N.V.5
Sowter, H.M.6
Wykoff, C.C.7
Maher, E.R.8
Harris, A.L.9
Ratcliffe, P.J.10
Maxwell, P.H.11
-
47
-
-
0031040821
-
Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementery DNA sequence and expression in human and rat alimentary tracts
-
Pastorekova S, Parkkila S, Parkkila AK, Opavsky R, Zelnik V, Saarnio J, Pastorek J. Carbonic anhydrase IX, MN/CA IX: analysis of stomach complementery DNA sequence and expression in human and rat alimentary tracts. Gastroenterology 1997; 112: 398-408
-
(1997)
Gastroenterology
, vol.112
, pp. 398-408
-
-
Pastorekova, S.1
Parkkila, S.2
Parkkila, A.K.3
Opavsky, R.4
Zelnik, V.5
Saarnio, J.6
Pastorek, J.7
-
48
-
-
0035503362
-
Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer
-
Giatromanolaki A, Koukourakis MI, Sivridis E, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res 2001; 61: 7992-7998
-
(2001)
Cancer Res.
, vol.61
, pp. 7992-7998
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Sivridis, E.3
Pastorek, J.4
Wykoff, C.C.5
Gatter, K.C.6
Harris, A.L.7
-
49
-
-
0037156961
-
The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer
-
Turner KJ, Crew JP, Wykoff CC, Watson PH, Poulsom R, Pastorek J, Ratcliffe PJ, Cranston D, Harris AL. The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Br J Cancer 2002; 86: 1276-1282
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1276-1282
-
-
Turner, K.J.1
Crew, J.P.2
Wykoff, C.C.3
Watson, P.H.4
Poulsom, R.5
Pastorek, J.6
Ratcliffe, P.J.7
Cranston, D.8
Harris, A.L.9
-
50
-
-
1842852597
-
Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslationla stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells
-
Rafajova M, Zatovicova M, Kettmann R, Pastorek J, Pastorekova S. Induction by hypoxia combined with low glucose or low bicarbonate and high posttranslationla stability upon reoxygenation contribute to carbonic anhydrase IX expression in cancer cells. Int J Oncol 2004; 24: 995-1004
-
(2004)
Int. J. Oncol.
, vol.24
, pp. 995-1004
-
-
Rafajova, M.1
Zatovicova, M.2
Kettmann, R.3
Pastorek, J.4
Pastorekova, S.5
-
51
-
-
0032894811
-
Study of in vitro conditions modulating expression of MN/CA IX protein in human cell lines derived from cervical carcinoma
-
Lieskovska J, Opavsky R, Zacikova L, Glasova M, Pastorek J, Pastorekova S. Study of in vitro conditions modulating expression of MN/CA IX protein in human cell lines derived from cervical carcinoma. Neoplasma 1997; 46: 17-24
-
(1997)
Neoplasma
, vol.46
, pp. 17-24
-
-
Lieskovska, J.1
Opavsky, R.2
Zacikova, L.3
Glasova, M.4
Pastorek, J.5
Pastorekova, S.6
-
52
-
-
0036682009
-
Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1a stabilization: A role for phosphatidylinositol 3′-kinase
-
Kaluz S, Kaluzova M, Chrastina A, Olive PL, Pastorekova S, Pastorek J, Lerman MI, Stanbridge EJ. Lowered oxygen tension induces expression of the hypoxia marker MN/carbonic anhydrase IX in the absence of hypoxia-inducible factor 1a stabilization: a role for phosphatidylinositol 3′-kinase. Cancer Res 2002; 62: 4469-4477
-
(2002)
Cancer Res.
, vol.62
, pp. 4469-4477
-
-
Kaluz, S.1
Kaluzova, M.2
Chrastina, A.3
Olive, P.L.4
Pastorekova, S.5
Pastorek, J.6
Lerman, M.I.7
Stanbridge, E.J.8
-
53
-
-
0029846376
-
Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by cell density
-
Koura AN, Liu W, Kitadai Y, Singh RK, Radinsky R, Ellis LM. Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by cell density. Cancer Res 1996; 56: 3891-3894
-
(1996)
Cancer Res.
, vol.56
, pp. 3891-3894
-
-
Koura, A.N.1
Liu, W.2
Kitadai, Y.3
Singh, R.K.4
Radinsky, R.5
Ellis, L.M.6
-
54
-
-
0031901109
-
High cell density induces vascular endothelial growth factor expression via protein tyrosine phosphorylation
-
Mukhopadhyay D, Tsiokas L, Sukhatme VP. High cell density induces vascular endothelial growth factor expression via protein tyrosine phosphorylation. Gene Expr 1998; 7: 53-60
-
(1998)
Gene Expr.
, vol.7
, pp. 53-60
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Sukhatme, V.P.3
-
55
-
-
0028870050
-
Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
-
Shweiki D, Neeman M, Itin A, Keshet E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis. Proc Natl Acad Sci USA 1995; 92: 768-772
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 768-772
-
-
Shweiki, D.1
Neeman, M.2
Itin, A.3
Keshet, E.4
-
56
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995; 375: 577-581
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
57
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 1996; 16: 4604-4613
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
58
-
-
0034650744
-
Oncogenes and tumor angiogenesis: Differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts
-
Rak J, Mitsuhashi Y, Sheehan C, Tamir A, Viloria-Petit A, Filmus J, Mansour SJ, Ahn NG, Kerbel RS. Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts. Cancer Res 2000; 60: 490-498
-
(2000)
Cancer Res.
, vol.60
, pp. 490-498
-
-
Rak, J.1
Mitsuhashi, Y.2
Sheehan, C.3
Tamir, A.4
Viloria-Petit, A.5
Filmus, J.6
Mansour, S.J.7
Ahn, N.G.8
Kerbel, R.S.9
-
59
-
-
0035187771
-
Vascular endothelial growth factor: Its prognostic, predictive, and therapeutic implications
-
Toi M, Matsumoto T, Bando H. Vascular endothelial growth factor: its prognostic, predictive, and therapeutic implications. Lancet Oncol 2001; 2: 667-673
-
(2001)
Lancet Oncol.
, vol.2
, pp. 667-673
-
-
Toi, M.1
Matsumoto, T.2
Bando, H.3
|