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Volumn 64, Issue 5, 2003, Pages 1671-1674

VHL down-regulation and differential localization as mechanisms in tumorigenesis

Author keywords

Down regulation; Immunohistochemistry; Localization; Membrane; Renal tumor; Von Hippel Lindau

Indexed keywords

PROTEIN; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

EID: 0142187245     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00257.x     Document Type: Article
Times cited : (8)

References (22)
  • 2
    • 0036718539 scopus 로고    scopus 로고
    • Molecular basis of the VHL hereditary cancer syndrome
    • KAELIN WG, JR: Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer 2:673-682, 2002
    • (2002) Nat Rev Cancer , vol.2 , pp. 673-682
    • Kaelin W.G., Jr.1
  • 3
    • 0037326037 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis
    • PUGH CW, RATCLIFFE PJ: The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Semin Cancer Biol 13:83-89, 2003
    • (2003) Semin Cancer Biol , vol.13 , pp. 83-89
    • Pugh, C.W.1    Ratcliffe, P.J.2
  • 4
    • 0141885019 scopus 로고    scopus 로고
    • The von Hippel-Lindau gene and protein in tumorigenesis and angiogenesis: A potential target for therapeutic designs
    • SHIAO YH: The von Hippel-Lindau gene and protein in tumorigenesis and angiogenesis: a potential target for therapeutic designs. Curr Med Chem 10:2461-2470, 2003
    • (2003) Curr Med Chem , vol.10 , pp. 2461-2470
    • Shiao, Y.H.1
  • 5
    • 0027954044 scopus 로고
    • Mutations of the VHL tumour suppressor gene in renal carcinoma
    • GNARRA JR, TORY K, WENG Y, et al: Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet 7:85-90, 1994
    • (1994) Nat Genet , vol.7 , pp. 85-90
    • Gnarra, J.R.1    Tory, K.2    Weng, Y.3
  • 6
    • 0344330996 scopus 로고    scopus 로고
    • Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma
    • GNARRA JR, DUAN DR, WENG Y, et al: Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochim Biophys Acta 1242:201-210, 1996
    • (1996) Biochim Biophys Acta , vol.1242 , pp. 201-210
    • Gnarra, J.R.1    Duan, D.R.2    Weng, Y.3
  • 7
    • 0032545016 scopus 로고    scopus 로고
    • Von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors
    • SHIAO YH, RICE JM, ANDERSON LM, et al: von Hippel-Lindau gene mutations in N-nitrosodimethylamine-induced rat renal epithelial tumors. J Natl Cancer Inst 90:1720-1723, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1720-1723
    • Shiao, Y.H.1    Rice, J.M.2    Anderson, L.M.3
  • 8
    • 0029772338 scopus 로고    scopus 로고
    • Expression pattern of the von Hippel-Lindau protein in human tissues
    • LOS M, JANSEN GH, KAELIN WG, et al: Expression pattern of the von Hippel-Lindau protein in human tissues. Lab Invest 75:231-238, 1996
    • (1996) Lab Invest , vol.75 , pp. 231-238
    • Los, M.1    Jansen, G.H.2    Kaelin, W.G.3
  • 9
    • 0030948396 scopus 로고    scopus 로고
    • Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues
    • CORLESS CL, KIBEL AS, ILIOPOULOS O, KAELIN WG, JR: Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues. Hum Pathol 28:459-464, 1997
    • (1997) Hum Pathol , vol.28 , pp. 459-464
    • Corless, C.L.1    Kibel, A.S.2    Iliopoulos, O.3    Kaelin W.G., Jr.4
  • 10
    • 0033052893 scopus 로고    scopus 로고
    • Expression of von Hippel-Lindau protein in normal and pathological human tissues
    • SAKASHITA N, TAKEYA M, KISHIDA T, et al: Expression of von Hippel-Lindau protein in normal and pathological human tissues. Histochem J 31:133-144, 1999
    • (1999) Histochem J , vol.31 , pp. 133-144
    • Sakashita, N.1    Takeya, M.2    Kishida, T.3
  • 11
    • 0037120977 scopus 로고    scopus 로고
    • VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma
    • YAO M, YOSHIDA M, KISHIDA T, et al: VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma. J Natl Cancer Inst 94:1569-1575, 2002
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1569-1575
    • Yao, M.1    Yoshida, M.2    Kishida, T.3
  • 12
    • 0037042183 scopus 로고    scopus 로고
    • Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors
    • SHIAO YH, RAMAKRISHNA G, ANDERSON LM, et al: Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors. Cancer Lett 179:33-38, 2002
    • (2002) Cancer Lett , vol.179 , pp. 33-38
    • Shiao, Y.H.1    Ramakrishna, G.2    Anderson, L.M.3
  • 13
    • 0030842661 scopus 로고    scopus 로고
    • Polymerase chain reaction-single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers
    • SHIAO YH, DIWAN BA, PERANTONI AO, et al: Polymerase chain reaction-single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers. Mol Carcinog 19:230-235, 1997
    • (1997) Mol Carcinog , vol.19 , pp. 230-235
    • Shiao, Y.H.1    Diwan, B.A.2    Perantoni, A.O.3
  • 14
    • 0032979092 scopus 로고    scopus 로고
    • Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas
    • YANG K, LINDBLAD P, EGEVAD L, HEMMINKI K: Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas. Cancer Lett 141:1-8, 1999
    • (1999) Cancer Lett , vol.141 , pp. 1-8
    • Yang, K.1    Lindblad, P.2    Egevad, L.3    Hemminki, K.4
  • 15
    • 0035974910 scopus 로고    scopus 로고
    • VHL gene alterations in renal cell carcinoma patients: Novel hotspot or founder mutations and linkage disequilibrium
    • MA X, YANG K, LINDBLAD P, et al: VHL gene alterations in renal cell carcinoma patients: novel hotspot or founder mutations and linkage disequilibrium. Oncogene 20:5393-5400, 2001
    • (2001) Oncogene , vol.20 , pp. 5393-5400
    • Ma, X.1    Yang, K.2    Lindblad, P.3
  • 16
    • 0036258790 scopus 로고    scopus 로고
    • Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: Relation to dietary and other factors
    • HEMMINKI K, JIANG Y, MA X, et al: Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: relation to dietary and other factors. Carcinogenesis 23:809-815, 2002
    • (2002) Carcinogenesis , vol.23 , pp. 809-815
    • Hemminki, K.1    Jiang, Y.2    Ma, X.3
  • 17
    • 0014478505 scopus 로고
    • The results of radical nephrectomy for renal cell carcinoma
    • ROBSON CJ, CHURCHILL BM. ANDERSON W: The results of radical nephrectomy for renal cell carcinoma. J Urol 101:297-301, 1969
    • (1969) J Urol , vol.101 , pp. 297-301
    • Robson, C.J.1    Churchill, B.M.2    Anderson, W.3
  • 18
    • 0029147430 scopus 로고
    • Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C
    • KIBEL A, ILIOPOULOS O, DECAPRIO JA, KAELIN WG, JR: Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C. Science 269:1444-1446, 1995
    • (1995) Science , vol.269 , pp. 1444-1446
    • Kibel, A.1    Iliopoulos, O.2    Decaprio, J.A.3    Kaelin W.G., Jr.4
  • 19
    • 0034214361 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor targets to mitochondria
    • SHIAO YH, RESAU JH, NAGASHIMA K, et al: The von Hippel-Lindau tumor suppressor targets to mitochondria. Cancer Res 60:2816-2819, 2000
    • (2000) Cancer Res , vol.60 , pp. 2816-2819
    • Shiao, Y.H.1    Resau, J.H.2    Nagashima, K.3
  • 20
    • 0141999621 scopus 로고    scopus 로고
    • Role of the von Hippel-Lindau gene and protein in kidney tumor phenotypes: Animal models
    • SHIAO YH: Role of the von Hippel-Lindau gene and protein in kidney tumor phenotypes: animal models. Rec Res Dev Histopathol 1:21-37, 2002; www.researchsignpost.com
    • (2002) Rec Res Dev Histopathol , vol.1 , pp. 21-37
    • Shiao, Y.H.1
  • 21
    • 0034961314 scopus 로고    scopus 로고
    • Specific von Hippel-Lindau protein expression of clear cell renal cell carcinoma with "immunogenic" features
    • MAGYARLAKI T, BUZOGANY I, NAGY J: Specific von Hippel-Lindau protein expression of clear cell renal cell carcinoma with "immunogenic" features. Pathol Oncol Res 7:42-45, 2001
    • (2001) Pathol Oncol Res , vol.7 , pp. 42-45
    • Magyarlaki, T.1    Buzogany, I.2    Nagy, J.3
  • 22
    • 0035892366 scopus 로고    scopus 로고
    • Molecular genetic analysis of the von Hippel-Lindau and human peroxisome proliferator-activated receptor gamma tumor-suppressor genes in adenocarcinomas of the gastroesophageal junction
    • WIJNHOVEN BP, LINDSTEDT EW, ABBOU M, et al: Molecular genetic analysis of the von Hippel-Lindau and human peroxisome proliferator-activated receptor gamma tumor-suppressor genes in adenocarcinomas of the gastroesophageal junction. Int J Cancer 94:891-895, 2001
    • (2001) Int J Cancer , vol.94 , pp. 891-895
    • Wijnhoven, B.P.1    Lindstedt, E.W.2    Abbou, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.