Molecular mousetraps and the serpinopathies

Biochemical Society Transactions

Volumn 33, Issue 2, 2005, Pages 321-330

  Lomas, D A ^a   Belorgey, D ^a   Mallya, M ^a   Miranda, E ^a   Kinghorn, K J ^a   Sharp, L K ^a   Phillips, R L ^a   Page, R ^a   Robertson, A S ^a   Crowther, D C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

1 antitrypsin; Conformational disease; Neuroserpin; Polymerization; Proteinase; Serpin

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 1 ANTITRYPSIN; ANTITHROMBIN; COMPLEMENT COMPONENT C1S INHIBITOR; SERINE PROTEINASE INHIBITOR;

ANALYTIC METHOD; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; DEMENTIA; ENDOPLASMIC RETICULUM; MOLECULAR MECHANICS; PHASE TRANSITION; POINT MUTATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN FAMILY; STRUCTURE ANALYSIS;

ANIMALS; ANTITHROMBINS; BIOPOLYMERS; HUMANS; LUNG DISEASES; SERINE PROTEINASE INHIBITORS; SERPINS;

EID: 20944443625     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0330321     Document Type: Conference Paper

References (80)

1. Silverman, G.A., Bird, P.I., Carrell, R.W., Church, F.C., Coughlin, P.B., Gettins, P., Irving, J., Lomas, D.A., Moyer, R.W., Pemberton, P. et al. (2001) J. Biol. Chem. 276, 33293-33296
2. Elliott, P.R., Lomas, D.A., Carrell, R.W. and Abrahams, J.-P. (1996) Nat. Struct. Biol. 3, 676-681
3. Ryu, S.-E., Choi, H.-J., Kwon, K.-S., Lee, K.N. and Yu, M.-H. (1996) Structure 4, 1181-1192
4. Elliott, P.R., Abrahams, J.-P. and Lomas, D.A. (1998) J. Mol. Biol. 275, 419-425
5. Elliott, P.R., Pei, X.Y., Dafforn, T.R. and Lomas, D.A. (2000) Protein Sci. 9, 1274-1281
6. Kim, S.-J., Woo, J.-R., Seo, E.J., Yu, M.-H. and Ryu, S.-E. (2001) J. Mol. Biol. 306, 109-119
7. Jin, L., Abrahams, J.-P., Skinner, R., Petitou, M., Pike, R. and Carrell, R.W. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 14683-14688
8. Li, J., Wang, Z., Canagarajah, B., Jiang, H., Kanost, M. and Goldsmith, E.J. (1999) Structure 7, 103-109
9. Johnson, D. and Travis, J. (1978) J. Biol. Chem. 253, 7142-7144
10. Wilczynska, M., Fa, M., Ohlsson, P.-I. and Ny, T. (1995) J. Biol. Chem. 270, 29652-29655
11. Wilczynska, M., Fa, M., Karolin, J., Ohlsson, P.-I., Johansson, L.B.-A. and Ny, T. (1997) Nat. Struct. Biol. 4, 354-357
12. Stratikos, E. and Gettins, P.G.W. (1997) Proc. Natl. Acad. Sci. U.S.A. 4, 453-458
13. Stratikos, E. and Gettins, P.G.W. (1998) J. Biol. Chem. 273, 15582-15589
14. Stratikos, E. and Gettins, P.G.W. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 4808-4813
15. Huntington, J.A., Read, R.J. and Carrell, R.W. (2000) Nature (London) 407, 923-926
16. Mast, A.E., Enghild, J.J., Pizzo, S.V. and Salvesen, G. (1991) Biochemistry 30, 1723-1730
17. Nykjær, A., Petersen, C.M., Møller, B., Jensen, P.M., Moestrup, S.K., Holtet, T.L., Etzerodt, M., Thøgersen, H.C., Munch, M., Andreasen, P.A. et al. (1992) J. Biol. Chem. 267, 14543-14546
18. Andreasen, P.A., Sottrup-Jensen, L., Kjøller, L., Nykjær, A., Moestrup, S.K., Petersen, C.M. and Gliemann, J. (1994) FEBS Lett. 338, 239-245
19. Lomas, D.A. and Carrell, R.W. (2002) Nat. Rev. Genet. 3, 759-768
20. Lomas, D.A. and Mahadeva, R. (2002) J. Clin. Invest. 110, 1585-1590
21. Carrell, R.W. and Lomas, D.A. (2002) N. Engl. J. Med. 346, 45-53
22. Billingsley, G.D., Walter, M.A., Hammond, G.L. and Cox, D.W. (1993) Am. J. Hum. Genet. 52, 343-353
23. Brantly, M., Nukiwa, T. and Crystal, R.G. (1988) Am. J. Med. 84 (Suppl. 6A), 13-31
24. Blanco, I., Fernández, E. and Bustillo, E.F. (2001) Clin. Genet. 60, 31-41
25. Lomas, D.A., Evans, D.L., Finch, J.T. and Carrell, R.W. (1992) Nature (London) 357, 605-607
26. Janciauskiene, S., Dominaitiene, R., Sternby, N.H., Piitulainen, E. and Eriksson, S. (2002) J. Biol. Chem. 277, 26540-26546
27. Dafforn, T.R., Mahadeva, R., Elliott, P.R., Sivasothy, P. and Lomas, D.A. (1999) J. Biol. Chem. 274, 9548-9555
28. Sivasothy, P., Dafforn, T.R., Gettins, P.G.W. and Lomas, D.A. (2000) J. Biol. Chem. 275, 33663-33668
29. Wu, Y., Swulius, M.T., Moremen, K.W. and Sifers, R.N. (2003) Proc. Natl. Acad. Sci. U.S.A. 100, 8229-8234
30. Janciauskiene, S., Eriksson, S., Callea, F., Mallya, M., Zhou, A., Seyama, K., Hata, S. and Lomas, D.A. (2004) Hepatology 40, 1203-1210
31. Seyama, K., Nukiwa, T., Takabe, K., Takahashi, H., Miyake, K. and Kira, S. (1991) J. Biol. Chem. 266, 12627-12632
32. Seyama, K., Nukiwa, T., Souma, S., Shimizu, K. and Kira, S. (1995) Am. Rev. Respir. Dis. 152, 2119-2126
33. Roberts, E.A., Cox, D.W., Medline, A. and Wanless, I.R. (1984) Am. J. Clin. Pathol. 82, 424-427
34. Matsunaga, E., Shiokawa, S., Nakamura, H., Maruyama, T., Tsuda, K. and Fukumaki, Y. (1990) Am. J. Hum. Genet. 46, 602-612
35. Sergi, C., Consalez, G.C., Fabbretti, G., Brisigotti, M., Faa, G., Costa, V., Romeo, G. and Callea, F. (1994) Lab. Invest. 70, 130-133
36. Zhou, A., Stein, P.E., Huntington, J.A. and Carrell, R.W. (2003) J. Biol. Chem. 278, 15116-15122
37. Kim, J., Lee, K.N., Yi, G.-S. and Yu, M.-H. (1995) J. Biol. Chem. 270, 8597-8601
38. Kang, H.A., Lee, K.N. and Yu, M.-H. (1997) J. Biol. Chem. 272, 510-516
39. Lomas, D.A., Finch, J.T., Seyama, K., Nukiwa, T. and Carrell, R.W. (1993) J. Biol. Chem. 268, 15333-15335
40. Lomas, D.A., Elliott, P.R., Sidhar, S.K., Foreman, R.C., Finch, J.T., Cox, D.W., Whisstock, J.C. and Carrell, R.W. (1995) J. Biol. Chem. 270, 16864-16870
41. Elliott, P.R., Stein, P.E., Bilton, D., Carrell, R.W. and Lomas, D.A. (1996) Nat. Struct. Biol. 3, 910-911
42. Mahadeva, R., Chang, W.-S.W., Dafforn, T., Oakley, D.J., Foreman, R.C., Calvin, J., Wight, D. and Lomas, D.A. (1999) J. Clin. Invest. 103, 999-1006
43. Cruz, M., Molina, J.A., Pedrola, D. and Muñoz-López, F. (1975) Helv. Paediatr. Acta 30, 501-507
44. Campra, J.L., Craig, J.R., Peters, R.L. and Reynolds, T.B. (1973) Ann. Intern. Med. 78, 233-238
45. Wewers, M.D., Casolaro, M.A., Sellers, S.E., Swayze, S.C., McPhaul, K.M., Wittes, J.T. and Crystal, R.G. (1987) N. Engl. J. Med. 316, 1055-1062
46. Ogushi, F., Fells, G.A., Hubbard, R.C., Straus, S.D. and Crystal, R.G. (1987) J. Clin. Invest. 80, 1366-1374
47. Guzdek, A., Potempa, J., Dubin, A. and Travis, J. (1990) FEBS Lett. 272, 125-127
48. Lomas, D.A., Evans, D.L., Stone, S.R., Chang, W.-S.W. and Carrell, R.W. (1993) Biochemistry 32, 500-508
49. Llewellyn-Jones, C.G., Lomas, D.A., Carrell, R.W. and Stockley, R.A. (1994) Biochim. Biophys. Acta 1227, 155-160
50. Larsson, C. (1978) Acta Med. Scand. 204, 345-351
51. Janus, E.D., Phillips, N.T. and Carrell, R.W. (1985) Lancet i, 152-154
52. Elliott, P.R., Bilton, D. and Lomas, D.A. (1998) Am. J. Respir. Cell Mol. Biol. 18, 670-674
53. Parmar, J.S., Mahadeva, R., Reed, B.J., Farahi, N., Cadwallader, K., Bilton, D., Chilvers, E.R. and Lomas, D.A. (2002) Am. J. Respir. Cell Mol. Biol 26, 723-730
54. Mulgrew, A.T., Taggart, C.C., Lawless, M.W., Greene, C.M., Brantly, M.L., O'Neill, S.J. and McElvaney, N.G. (2004) Chest 125, 1952-1957
55. Morrison, H.M., Kramps, J.A., Burnett, D. and Stockley, R.A. (1987) Clin. Sci. 72, 373-381
56. Rouhani, F., Paone, G., Smith, N.K., Krein, P., Barnes, P. and Brantly, M.L. (2000) Chest 2S0S-2S1S
57. Banda, M.J., Rice, A.G., Griffin, G.L. and Senior, R.M. (1988) J. Exp. Med. 167, 1608-1615
58. Senior, R.M., Griffin, G.L. and Mecham, R.P. (1980) J. Clin. Invest. 66, 859-862
59. Corral, J., Aznar, J., Gonzalez-Conejero, R., Villa, P., Minano, A., Vaya, A., Carrell, R.W., Huntington, J.A. and Vicente, V. (2004) Circulation 110, 1303-1307
60. Green, C., Brown, G., Dafforn, T.R., Morley, T., Lomas, D.A. and Gubb, D. (2003) Development 130, 1473-1478
61. Davis, R.L., Holohan, P.D., Shrimpton, A.E., Tatum, A., Daucher, J., Collins, G.H., Todd, R., Bradshaw, C., Kent, P., Feiglin, D. et al. (1999) Am. J. Pathol. 155, 1901-1913
62. Davis, R.L., Shrimpton, A.E., Holohan, P.D., Bradshaw, C., Feiglin, D., Sonderegger, P., Kinter, J., Becker, L.M., Lacbawan, F., Krasnewich, D. et al. (1999) Nature (London) 401, 376-379
63. Bradshaw, C.B., Davis, R.L., Shrimpton, A.E., Holohan, P.D., Rea, C.B., Fieglin, D., Kent, P. and Collins, G.H. (2001) Arch. Neurol. 58, 1429-1434
64. Davis, R.L., Shrimpton, A.E., Carrell, R.W., Lomas, D.A., Gerhard, L., Baumann, B., Lawrence, D.A., Yepes, M., Kim, T.S., Ghetti, B. et al. (2002) Lancet 359, 2242-2247
65. Belorgey, D., Crowther, D.C., Mahadeva, R. and Lomas, D.A. (2002) J. Biol. Chem. 277, 17367-17373
66. Belorgey, D., Sharp, L.K., Crowther, D.C., Onda, M., Johansson, J. and Lomas, D.A. (2004) Eur. J. Biochem. 271, 3360-3367
67. Miranda, E., Römisch, K. and Lomas, D.A. (2004) J. Biol. Chem. 279, 28283-28291
68. Schulze, A.J., Baumann, U., Knof, S., Jaeger, E., Huber, R. and Laurell, C.-B. (1990) Eur. J. Biochem. 194, 51-56
69. Mast, A.E., Enghild, J.J. and Salvesen, G. (1992) Biochemistry 31, 2720-2728
70. Huntington, J.A., Pannu, N.S., Hazes, B., Read, R., Lomas, D.A. and Carrell, R.W. (1999) J. Mol. Biol. 293, 449-455
71. Dunstone, MA, Dai, W., Whisstock, J.C., Rossjohn, J., Pike, R.N., Feil, S.C., Le Bonniec, B.F., Parker, M.W. and Bottomley, S.P. (2000) Protein Sci. 9, 417-420
72. Skinner, R., Chang, W.-S.W., Jin, L., Pei, X., Huntington, J.A., Abrahams, J.-P., Carrell, R.W. and Lomas, D.A. (1998) J. Mol. Biol. 283, 9-14
73. Fitton, H.L., Pike, R.N., Carrell, R.W. and Chang, W.-S.W. (1997) Biol. Chem. 378, 1059-1063
74. Chang, W.-S.W., Wardell, M.R., Lomas, D.A. and Carrell, R.W. (1996) Biochem. J. 314, 647-653
75. Mahadeva, R., Dafforn, T.R., Carrell, R.W. and Lomas, D.A. (2002) J. Biol. Chem. 277, 6771-6774
76. Parfrey, H., Dafforn, T.R., Belorgey, D., Lomas, D.A. and Mahadeva, R. (2004) Am. J. Respir. Cell Mol. Biol. 31, 133-139
77. Zhou, A., Stein, P.E., Huntington, J.A., Sivasothy, P., Lomas, D.A. and Carrell, R.W. (2004) J. Mol. Biol. 342, 931-941
78. Lee, C., Maeng, J.-S., Kocher, J.-P., Lee, B. and Yu, M.-H. (2001) Protein Sci. 10, 1446-1453
79. Parfrey, H., Mahadeva, R., Ravenhill, N., Zhou, A., Dafforn, T.R., Foreman, R.C. and Lomas, D.A. (2003) J. Biol. Chem. 278, 33060-33066
80. Gooptu, B., Hazes, B., Chang, W.-S.W., Dafforn, T.R., Carrell, R.W., Read, R. and Lomas, D.A. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 67-72