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Volumn 277, Issue 9, 2002, Pages 6771-6774
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6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z α1-antitrypsin-related cirrhosis
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Author keywords
[No Author keywords available]
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Indexed keywords
CONFORMATIONS;
DISEASES;
POLYMERIZATION;
PROTEINS;
INCLUSION BODIES;
BIOCHEMISTRY;
ALPHA 1 ANTITRYPSIN;
MUTANT PROTEIN;
PEPTIDE;
PHENYLALANYLLEUCYLGLUTAMYLALANYLISOLEUCYLGLYCINE;
SERINE PROTEINASE INHIBITOR;
UNCLASSIFIED DRUG;
ALPHA 1 ANTITRYPSIN DEFICIENCY;
ARTICLE;
BETA SHEET;
GENE MUTATION;
LIVER CIRRHOSIS;
PRIORITY JOURNAL;
PROTEIN BINDING;
PROTEIN CONFORMATION;
PROTEIN POLYMERIZATION;
PROTEIN TERTIARY STRUCTURE;
STRUCTURE ANALYSIS;
ACRYLAMIDE;
ALPHA 1-ANTITRYPSIN;
ALPHA 1-ANTITRYPSIN DEFICIENCY;
ELECTROPHORESIS, POLYACRYLAMIDE GEL;
ENDOPLASMIC RETICULUM;
HUMANS;
KINETICS;
MODELS, MOLECULAR;
MUTATION;
PEPTIDES;
PROTEIN BINDING;
PROTEIN CONFORMATION;
PROTEIN STRUCTURE, SECONDARY;
PROTEIN STRUCTURE, TERTIARY;
SERPINS;
TIME FACTORS;
UREA;
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EID: 0036510604
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.C100722200 Document Type: Article |
Times cited : (149)
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References (39)
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