A 2.1 Å resolution structure of an uncleaved α1-antitrypsin shows variability of the reactive center and other loops

Journal of Molecular Biology

Volumn 306, Issue 1, 2001, Pages 109-119

  Kim, Seung Jun ^a   Woo, Joo Rang ^a   Seo, Eun Joo ^b   Yu, Myeong Hee ^b   Ryu, Seong Eon ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Reactive center loop; Serpins; Surface cavity; Van der Waals strain; 1 antitrypsin

Indexed keywords

ALPHA 1 ANTITRYPSIN; SERINE PROTEINASE INHIBITOR;

ARTICLE; BETA SHEET; BLOOD CLOTTING; CELL DIFFERENTIATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME STRUCTURE; INFLAMMATION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PLIABILITY; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

ALPHA 1-ANTITRYPSIN; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLIABILITY; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; THERMODYNAMICS;

EID: 0035830479     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4357     Document Type: Article

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