Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures

Journal of Medicinal Chemistry

Volumn 39, Issue 9, 1996, Pages 1885-1897

  Avery, Mitchell A ^a   Fan, Pingchen ^c   Karle, Jean M ^b   Bonk, Jason D ^a   Miller, Robert ^b   Goins, D Keith ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

10 DEOXO 13 CARBAARTEMISININ; 13 CARBAARTEMISININ DERIVATIVE; ANTIMALARIAL AGENT; ARTEMISIN; ARTEMISIN DERIVATIVE; ENDOPEROXIDE; EPOXIDE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PLASMODIUM FALCIPARUM; SESQUITERPENES; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029886413     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950921y     Document Type: Article

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