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Volumn 128, Issue 7, 2005, Pages 2042-2053

Interferon-γ inhibits hepatitis B virus-induced NF-κB activation through nuclear localization of NF-κB-inducing kinase

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOTRANSFERASE;

EID: 20444500040     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2005.03.002     Document Type: Article
Times cited : (23)

References (55)
  • 1
    • 0033135443 scopus 로고    scopus 로고
    • More than third of world's population has been infected with hepatitis B virus (letter)
    • A.J. Zuckerman More than third of world's population has been infected with hepatitis B virus (letter) BMJ 318 1999 1213
    • (1999) BMJ , vol.318 , pp. 1213
    • Zuckerman, A.J.1
  • 2
    • 0023933449 scopus 로고
    • Hepatitis B virus. The major etiology of hepatocellular carcinoma
    • R.P. Beasley Hepatitis B virus. The major etiology of hepatocellular carcinoma Cancer 61 1988 1942 1956
    • (1988) Cancer , vol.61 , pp. 1942-1956
    • Beasley, R.P.1
  • 3
    • 0032853956 scopus 로고    scopus 로고
    • Hepatitis B virus in hepatocarcinogenesis
    • M.A. Feitelson Hepatitis B virus in hepatocarcinogenesis J Cell Physiol 181 1999 188 202
    • (1999) J Cell Physiol , vol.181 , pp. 188-202
    • Feitelson, M.A.1
  • 4
    • 0033860678 scopus 로고    scopus 로고
    • Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC)
    • C. Brechot, D. Gozuacik, Y. Murakami, P. Paterlini-Brechot Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) Semin Cancer Biol 10 2000 211 231
    • (2000) Semin Cancer Biol , vol.10 , pp. 211-231
    • Brechot, C.1    Gozuacik, D.2    Murakami, Y.3    Paterlini-Brechot, P.4
  • 6
    • 0035731540 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatitis B virus-associated liver cancer
    • C. Rabe, B. Cheng, W.H. Caselmann Molecular mechanisms of hepatitis B virus-associated liver cancer Dig Dis 19 2001 279 287
    • (2001) Dig Dis , vol.19 , pp. 279-287
    • Rabe, C.1    Cheng, B.2    Caselmann, W.H.3
  • 7
    • 0037376895 scopus 로고    scopus 로고
    • NF-kappaB in cancer: a marked target
    • A. Lin, M. Karin NF-kappaB in cancer a marked target Semin Cancer Biol 13 2003 107 114
    • (2003) Semin Cancer Biol , vol.13 , pp. 107-114
    • Lin, A.1    Karin, M.2
  • 8
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB
    • A.S. Baldwin Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB J Clin Invest 107 2001 241 246
    • (2001) J Clin Invest , vol.107 , pp. 241-246
    • Baldwin, A.S.1
  • 9
    • 1842640502 scopus 로고    scopus 로고
    • Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation
    • E.M. Sorokina, J.J. Merlo Jr, A.Y. Tsygankov Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation J Biol Chem 279 2004 13469 13477
    • (2004) J Biol Chem , vol.279 , pp. 13469-13477
    • Sorokina, E.M.1    Merlo J.J. Jr2    Tsygankov, A.Y.3
  • 10
    • 0034812556 scopus 로고    scopus 로고
    • Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation
    • X. Li, J. Josef, W.A. Marasco Hiv-1 Tat can substantially enhance the capacity of NIK to induce IkappaB degradation Biochem Biophys Res Commun 286 2001 587 594
    • (2001) Biochem Biophys Res Commun , vol.286 , pp. 587-594
    • Li, X.1    Josef, J.2    Marasco, W.A.3
  • 11
    • 0032544010 scopus 로고    scopus 로고
    • Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-κB through a pathway that includes the NF-κB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta
    • B.S. Sylla, S.C. Hung, D.M. Davidson, E. Hatzivassiliou, N.L. Malinin, D. Wallach, T.D. Gilmore, E. Kieff, G. Mosialos Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-κB through a pathway that includes the NF-κB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta Proc Natl Acad Sci U S A 95 1998 10106 10111
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 10106-10111
    • Sylla, B.S.1    Hung, S.C.2    Davidson, D.M.3    Hatzivassiliou, E.4    Malinin, N.L.5    Wallach, D.6    Gilmore, T.D.7    Kieff, E.8    Mosialos, G.9
  • 12
    • 0035515221 scopus 로고    scopus 로고
    • Additive activation of hepatic NF-kappaB by ethanol and hepatitis B protein X (HBX) or HCV core protein: involvement of TNF-alpha receptor 1-independent and -dependent mechanisms
    • W.H. Kim, F. Hong, B. Jaruga, Z. Hu, S. Fan, T.J. Liang, B. Gao Additive activation of hepatic NF-kappaB by ethanol and hepatitis B protein X (HBX) or HCV core protein: involvement of TNF-alpha receptor 1-independent and -dependent mechanisms FASEB J 15 2001 2551 2553
    • (2001) FASEB J , vol.15 , pp. 2551-2553
    • Kim, W.H.1    Hong, F.2    Jaruga, B.3    Hu, Z.4    Fan, S.5    Liang, T.J.6    Gao, B.7
  • 13
    • 0031813289 scopus 로고    scopus 로고
    • Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases
    • R. Geleziunas, S. Ferrell, X. Lin, Y. Mu, E.T. Cunningham Jr, M. Grant, M.A. Connelly, J.E. Hambor, K.B. Marcu, W.C. Greene Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases Mol Cell Biol 18 1998 5157 5165
    • (1998) Mol Cell Biol , vol.18 , pp. 5157-5165
    • Geleziunas, R.1    Ferrell, S.2    Lin, X.3    Mu, Y.4    Cunningham E.T. Jr5    Grant, M.6    Connelly, M.A.7    Hambor, J.E.8    Marcu, K.B.9    Greene, W.C.10
  • 14
    • 0037044189 scopus 로고    scopus 로고
    • NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival
    • C. Yun, H.R. Um, Y.H. Jin, J.H. Wang, M.O. Lee, S. Park, J.H. Lee, H. Cho NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival Cancer Lett 184 2002 97 104
    • (2002) Cancer Lett , vol.184 , pp. 97-104
    • Yun, C.1    Um, H.R.2    Jin, Y.H.3    Wang, J.H.4    Lee, M.O.5    Park, S.6    Lee, J.H.7    Cho, H.8
  • 15
    • 0142200342 scopus 로고    scopus 로고
    • Interferon alpha inhibits the nuclear factor kappa B activation triggered by X gene product of hepatitis B virus in human hepatoma cells
    • K. Ohata, T. Ichikawa, K. Nakao, M. Shigeno, D. Nishimura, H. Ishikawa, K. Hamasaki, K. Eguchi Interferon alpha inhibits the nuclear factor kappa B activation triggered by X gene product of hepatitis B virus in human hepatoma cells FEBS Lett 553 2003 304 308
    • (2003) FEBS Lett , vol.553 , pp. 304-308
    • Ohata, K.1    Ichikawa, T.2    Nakao, K.3    Shigeno, M.4    Nishimura, D.5    Ishikawa, H.6    Hamasaki, K.7    Eguchi, K.8
  • 16
    • 0037379219 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB
    • M. Biermer, R. Puro, R.J. Schneider Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB J Virol 77 2003 4033 4042
    • (2003) J Virol , vol.77 , pp. 4033-4042
    • Biermer, M.1    Puro, R.2    Schneider, R.J.3
  • 17
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
    • G. Waris, K.W. Huh, A. Siddiqui Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress Mol Cell Biol 21 2001 7721 7730
    • (2001) Mol Cell Biol , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 18
    • 0030756523 scopus 로고    scopus 로고
    • Activation of hepatitis B virus S promoter by the viral large surface protein via induction of stress in the endoplasmic reticulum
    • Z. Xu, G. Jensen, T.S. Yen Activation of hepatitis B virus S promoter by the viral large surface protein via induction of stress in the endoplasmic reticulum J Virol 71 1997 7387 7392
    • (1997) J Virol , vol.71 , pp. 7387-7392
    • Xu, Z.1    Jensen, G.2    Yen, T.S.3
  • 19
    • 0030296929 scopus 로고    scopus 로고
    • The hepatitis B virus large surface protein (LHBs) is a transcriptional activator
    • E. Hildt, G. Saher, V. Bruss, P.H. Hofschneider The hepatitis B virus large surface protein (LHBs) is a transcriptional activator Virology 225 1996 235 239
    • (1996) Virology , vol.225 , pp. 235-239
    • Hildt, E.1    Saher, G.2    Bruss, V.3    Hofschneider, P.H.4
  • 20
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • N.L. Malinin, M.P. Boldin, A.V. Kovalenko, D. Wallach MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1 Nature 385 1997 540 544
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 21
    • 0030611595 scopus 로고    scopus 로고
    • IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
    • J.D. Woronicz, X. Gao, Z. Cao, M. Rothe, D.V. Goeddel IkappaB kinase-beta NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK Science 278 1997 866 869
    • (1997) Science , vol.278 , pp. 866-869
    • Woronicz, J.D.1    Gao, X.2    Cao, Z.3    Rothe, M.4    Goeddel, D.V.5
  • 22
    • 0032583949 scopus 로고    scopus 로고
    • Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
    • H. Nakano, M. Shindo, S. Sakon, S. Nishinaka, M. Mihara, H. Yagita, K. Okumura Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1 Proc Natl Acad Sci U S A 95 1998 3537 3542
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3537-3542
    • Nakano, H.1    Shindo, M.2    Sakon, S.3    Nishinaka, S.4    Mihara, M.5    Yagita, H.6    Okumura, K.7
  • 23
    • 0031597368 scopus 로고    scopus 로고
    • Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase
    • S. Nemoto, J.A. DiDonato, A. Lin Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase Mol Cell Biol 18 1998 7336 7343
    • (1998) Mol Cell Biol , vol.18 , pp. 7336-7343
    • Nemoto, S.1    DiDonato, J.A.2    Lin, A.3
  • 24
    • 0035896422 scopus 로고    scopus 로고
    • Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice
    • L. Yin, L. Wu, H. Wesche, C.D. Arthur, J.M. White, D.V. Goeddel, R.D. Schreiber Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice Science 291 2001 2162 2165
    • (2001) Science , vol.291 , pp. 2162-2165
    • Yin, L.1    Wu, L.2    Wesche, H.3    Arthur, C.D.4    White, J.M.5    Goeddel, D.V.6    Schreiber, R.D.7
  • 25
    • 0035809310 scopus 로고    scopus 로고
    • Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I
    • A. Matsushima, T. Kaisho, P.D. Rennert, H. Nakano, K. Kurosawa, D. Uchida, K. Takeda, S. Akira, M. Matsumoto Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I J Exp Med 193 2001 631 636
    • (2001) J Exp Med , vol.193 , pp. 631-636
    • Matsushima, A.1    Kaisho, T.2    Rennert, P.D.3    Nakano, H.4    Kurosawa, K.5    Uchida, D.6    Takeda, K.7    Akira, S.8    Matsumoto, M.9
  • 26
    • 0035084913 scopus 로고    scopus 로고
    • Micrococci and peptidoglycan activate TLR2→MyD88→IRAK→ TRAF→NIK→IKK→NF-kappaB signal transduction pathway that induces transcription of interleukin-8
    • Q. Wang, R. Dziarski, C.J. Kirschning, M. Muzio, D. Gupta Micrococci and peptidoglycan activate TLR2→MyD88→IRAK→TRAF→NIK→ IKK→NF-kappaB signal transduction pathway that induces transcription of interleukin-8 Infect Immunol 69 2001 2270 2276
    • (2001) Infect Immunol , vol.69 , pp. 2270-2276
    • Wang, Q.1    Dziarski, R.2    Kirschning, C.J.3    Muzio, M.4    Gupta, D.5
  • 27
    • 0037428385 scopus 로고    scopus 로고
    • The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536
    • X. Jiang, N. Takahashi, N. Matsui, T. Tetsuka, T. Okamoto The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536 J Biol Chem 278 2003 919 926
    • (2003) J Biol Chem , vol.278 , pp. 919-926
    • Jiang, X.1    Takahashi, N.2    Matsui, N.3    Tetsuka, T.4    Okamoto, T.5
  • 28
    • 0037406703 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression
    • W.C. Huang, J.J. Chen, H. Inoue, C.C. Chen Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression J Immunol 170 2003 4767 4775
    • (2003) J Immunol , vol.170 , pp. 4767-4775
    • Huang, W.C.1    Chen, J.J.2    Inoue, H.3    Chen, C.C.4
  • 29
    • 5644302162 scopus 로고    scopus 로고
    • Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
    • P. Ramakrishnan, W. Wang, D. Wallach Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase Immunity 21 2004 477 489
    • (2004) Immunity , vol.21 , pp. 477-489
    • Ramakrishnan, P.1    Wang, W.2    Wallach, D.3
  • 30
    • 0030004897 scopus 로고    scopus 로고
    • Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
    • Z.J. Chen, L. Parent, T. Maniatis Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity Cell 84 1996 853 862
    • (1996) Cell , vol.84 , pp. 853-862
    • Chen, Z.J.1    Parent, L.2    Maniatis, T.3
  • 31
    • 0036717195 scopus 로고    scopus 로고
    • NF-kappa B, chemokine gene transcription and tumour growth
    • A. Richmond NF-kappa B, chemokine gene transcription and tumour growth Nat Rev Immunol 2 2002 664 674
    • (2002) Nat Rev Immunol , vol.2 , pp. 664-674
    • Richmond, A.1
  • 33
    • 0033998441 scopus 로고    scopus 로고
    • Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export
    • W.F. Tam, L.H. Lee, L. Davis, R. Sen Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export Mol Cell Biol 20 2000 2269 2284
    • (2000) Mol Cell Biol , vol.20 , pp. 2269-2284
    • Tam, W.F.1    Lee, L.H.2    Davis, L.3    Sen, R.4
  • 34
    • 0033953587 scopus 로고    scopus 로고
    • A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/ IkappaBalpha complexes
    • T.T. Huang, N. Kudo, M. Yoshida, S. Miyamoto A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes Proc Natl Acad Sci U S A 97 2000 1014 1019
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1014-1019
    • Huang, T.T.1    Kudo, N.2    Yoshida, M.3    Miyamoto, S.4
  • 35
    • 0037192823 scopus 로고    scopus 로고
    • Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus
    • A. Birbach, P. Gold, B.R. Binder, E. Hofer, R. de Martin, J.A. Schmid Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus J Biol Chem 277 2002 10842 10851
    • (2002) J Biol Chem , vol.277 , pp. 10842-10851
    • Birbach, A.1    Gold, P.2    Binder, B.R.3    Hofer, E.4    De Martin, R.5    Schmid, J.A.6
  • 37
    • 0028177983 scopus 로고
    • Interferon-gamma production specific for hepatitis B virus antigen by intrahepatic T lymphocytes in patients with acute and chronic hepatitis B
    • S. Kakumu, T. Ishikawa, T. Wakita, K. Yoshioka, M. Takayanagi, H. Tahara, A. Kusakabe Interferon-gamma production specific for hepatitis B virus antigen by intrahepatic T lymphocytes in patients with acute and chronic hepatitis B Am J Gastroenterol 89 1994 92 96
    • (1994) Am J Gastroenterol , vol.89 , pp. 92-96
    • Kakumu, S.1    Ishikawa, T.2    Wakita, T.3    Yoshioka, K.4    Takayanagi, M.5    Tahara, H.6    Kusakabe, A.7
  • 38
    • 0035140877 scopus 로고    scopus 로고
    • Pathogenesis of experimental neonatal woodchuck hepatitis virus infection: chronicity as an outcome of infection is associated with a diminished acute hepatitis that is temporally deficient for the expression of interferon gamma and tumor necrosis factor-alpha messenger RNAs
    • I. Nakamura, J.T. Nupp, M. Cowlen, W.C. Hall, B.C. Tennant, J.L. Casey, J.L. Gerin, P.J. Cote Pathogenesis of experimental neonatal woodchuck hepatitis virus infection: chronicity as an outcome of infection is associated with a diminished acute hepatitis that is temporally deficient for the expression of interferon gamma and tumor necrosis factor-alpha messenger RNAs Hepatology 33 2001 439 447
    • (2001) Hepatology , vol.33 , pp. 439-447
    • Nakamura, I.1    Nupp, J.T.2    Cowlen, M.3    Hall, W.C.4    Tennant, B.C.5    Casey, J.L.6    Gerin, J.L.7    Cote, P.J.8
  • 39
    • 0037213545 scopus 로고    scopus 로고
    • CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection
    • R. Thimme, S. Wieland, C. Steiger, J. Ghrayeb, K.A. Reimann, R.H. Purcell, F.V. Chisari CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection J Virol 77 2003 68 76
    • (2003) J Virol , vol.77 , pp. 68-76
    • Thimme, R.1    Wieland, S.2    Steiger, C.3    Ghrayeb, J.4    Reimann, K.A.5    Purcell, R.H.6    Chisari, F.V.7
  • 40
    • 0033617583 scopus 로고    scopus 로고
    • Viral clearance without destruction of infected cells during acute HBV infection
    • L.G. Guidotti, R. Rochford, J. Chung, M. Shapiro, R. Purcell, F.V. Chisari Viral clearance without destruction of infected cells during acute HBV infection Science 284 1999 825 829
    • (1999) Science , vol.284 , pp. 825-829
    • Guidotti, L.G.1    Rochford, R.2    Chung, J.3    Shapiro, M.4    Purcell, R.5    Chisari, F.V.6
  • 42
    • 0141891167 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication
    • S.G. Park, S.M. Lee, G. Jung Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication J Biol Chem 278 2003 39851 39857
    • (2003) J Biol Chem , vol.278 , pp. 39851-39857
    • Park, S.G.1    Lee, S.M.2    Jung, G.3
  • 45
    • 0000934401 scopus 로고
    • Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA
    • M.A. Sells, M.L. Chen, G. Acs Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA Proc Natl Acad Sci U S A 84 1987 1005 1009
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 1005-1009
    • Sells, M.A.1    Chen, M.L.2    Acs, G.3
  • 46
    • 0031972604 scopus 로고    scopus 로고
    • X-gene product of hepatitis B virus induces apoptosis in liver cells
    • H. Kim, H. Lee, Y. Yun X-gene product of hepatitis B virus induces apoptosis in liver cells J Biol Chem 273 1998 381 385
    • (1998) J Biol Chem , vol.273 , pp. 381-385
    • Kim, H.1    Lee, H.2    Yun, Y.3
  • 48
    • 0036721604 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages
    • D.R. Wesemann, Y. Dong, G.M. O'Keefe, V.T. Nguyen, E.N. Benveniste Suppressor of cytokine signaling 1 inhibits cytokine induction of CD40 expression in macrophages J Immunol 169 2002 2354 2360
    • (2002) J Immunol , vol.169 , pp. 2354-2360
    • Wesemann, D.R.1    Dong, Y.2    O'Keefe, G.M.3    Nguyen, V.T.4    Benveniste, E.N.5
  • 50
    • 0037134429 scopus 로고    scopus 로고
    • Critical role of tumor necrosis factor-alpha and NF-kappa B in interferon-gamma-induced CD40 expression in microglia/macrophages
    • V.T. Nguyen, E.N. Benveniste Critical role of tumor necrosis factor-alpha and NF-kappa B in interferon-gamma-induced CD40 expression in microglia/macrophages J Biol Chem 277 2002 13796 13803
    • (2002) J Biol Chem , vol.277 , pp. 13796-13803
    • Nguyen, V.T.1    Benveniste, E.N.2
  • 51
    • 0030889207 scopus 로고    scopus 로고
    • The IFN gamma receptor: a paradigm for cytokine receptor signaling
    • E.A. Bach, M. Aguet, R.D. Schreiber The IFN gamma receptor a paradigm for cytokine receptor signaling Annu Rev Immunol 15 1997 563 591
    • (1997) Annu Rev Immunol , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 52
    • 1242292306 scopus 로고    scopus 로고
    • STAT-1: a novel regulator of apoptosis
    • A. Stephanou, D.S. Latchman STAT-1 a novel regulator of apoptosis Int J Exp Pathol 84 2003 239 244
    • (2003) Int J Exp Pathol , vol.84 , pp. 239-244
    • Stephanou, A.1    Latchman, D.S.2
  • 54
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • M. Karin, Y. Cao, F.R. Greten, Z.W. Li NF-kappaB in cancer from innocent bystander to major culprit Nat Rev Cancer 2 2002 301 310
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 55
    • 0036787682 scopus 로고    scopus 로고
    • Imbalanced intrahepatic expression of interleukin 12, interferon gamma, and interleukin 10 in fulminant hepatitis B
    • L. Leifeld, S. Cheng, J. Ramakers, F.L. Dumoulin, C. Trautwein, T. Sauerbruch, U. Spengler Imbalanced intrahepatic expression of interleukin 12, interferon gamma, and interleukin 10 in fulminant hepatitis B Hepatology 36 2002 1001 1008
    • (2002) Hepatology , vol.36 , pp. 1001-1008
    • Leifeld, L.1    Cheng, S.2    Ramakers, J.3    Dumoulin, F.L.4    Trautwein, C.5    Sauerbruch, T.6    Spengler, U.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.