MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm

Journal of Biological Chemistry

Volumn 280, Issue 17, 2005, Pages 16651-16658

  Phelps, Monika ^a   Phillips, Anna ^a   Darley, Matthew ^a   Blaydes, Jeremy P ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; PROTEINS; SIGNALING; SYNTHESIS (CHEMICAL);

HDM2 ONCOPROTEIN; MEK-ERK SIGNALING; MRNA TRANSCRIPTION; SIGNALING PATHWAYS;

RNA;

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; ONCOPROTEIN; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ENZYME INHIBITOR; MDM2 PROTEIN, HUMAN; NITRILE; NUCLEAR PROTEIN; RNA;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CELL GROWTH; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; FIBROBLAST; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; POLYSOME; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; WILD TYPE; APOPTOSIS; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CYCLE; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; METABOLISM; PHYSIOLOGY; PLASMID; PROTEIN BINDING; REPORTER GENE; RNA PROCESSING; TIME; TUMOR CELL LINE;

MINK CELL FOCUS-FORMING VIRUS; MURINAE;

APOPTOSIS; BUTADIENES; CELL CYCLE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CYTOPLASM; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; IN SITU HYBRIDIZATION; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; NITRILES; NUCLEAR PROTEINS; PLASMIDS; PROTEIN BINDING; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; RNA; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 20444482051     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412334200     Document Type: Article

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