Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death

Journal of Neuroscience Research

Volumn 80, Issue 4, 2005, Pages 549-561

  Suzuki, Mari ^a   Koike, Tatsuro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

c Jun activation; Energy failure; Mitochondrial permeability transition; Protein delivery; Sympathetic neuron

Indexed keywords

CASPASE 3; CASPASE 7; CYCLIN D1; CYTOCHROME C; GLUTAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; POLYGLUTAMINE; PROTEIN C JUN; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL MEMBRANE; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVATION; MITOCHONDRIAL MEMBRANE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CASPASE 3; CASPASE 7; CASPASES; CELL COUNT; CELLS, CULTURED; CYCLIN D1; CYCLOHEXIMIDE; DIHYDROTACHYSTEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; FORSKOLIN; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; IONOPHORES; LACTIC ACID; MITOCHONDRIA; MODELS, BIOLOGICAL; NECROSIS; NERVE GROWTH FACTOR; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDES; PERMEABILITY; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAUROSPORINE; SUPERIOR CERVICAL GANGLION; TIME FACTORS;

EID: 20344391958     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20461     Document Type: Article

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