Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation

Journal of Biological Chemistry

Volumn 278, Issue 35, 2003, Pages 32537-32543

  Kavurma, Mary M ^b   Khachigian, Levon M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COMPLEXATION; PROTEINS; RNA;

RESTENOSIS;

ENZYME INHIBITION;

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; PROTEIN P21; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR SP1; ZINC FINGER PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; CELL PROLIFERATION; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RESTENOSIS; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

ANIMALS; APOPTOSIS; ARTERIES; BLOTTING, WESTERN; BROMODEOXYURIDINE; CDC2-CDC28 KINASES; CELL CYCLE; CELL DIVISION; CELL LINE; CELLS, CULTURED; CYCLIN D1; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ETOPOSIDE; GENES, DOMINANT; MUTATION; MYOCYTES, SMOOTH MUSCLE; NUCLEIC ACID SYNTHESIS INHIBITORS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RATS, INBRED WKY; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

ANIMALIA; EUKARYOTA;

EID: 0042358634     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305650200     Document Type: Article

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