P53-dependent transcriptional repression of p21waf1 by hepatitis C virus NS3

Journal of General Virology

Volumn 82, Issue 9, 2001, Pages 2235-2241

  Kwun, H J ^a   Jung, E Y ^a   Ahn, J Y ^a   Lee, M N ^a   Jang, K L ^a  

^a Pusan National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; PROTEIN P53; PROTEINASE; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL GROWTH; CELL LINE; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE ACTIVITY; GENE REPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; GROWTH RATE; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; VIRUS CORE;

EID: 0034852454     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-9-2235     Document Type: Article

References (23)

1. p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
2. Full genome cloning and nucleotide sequence analysis of hepatitis C virus from sera of chronic hepatitis patients in Korea
3. WAF1, a potential mediator of p53 tumor suppression
4. Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues
5. Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus
6. High efficiency gene transfer into mammalian cells
7. Hepatitis C virus
8. Complex formation of the nonstructural protein 3 of hepatitis C virus with the p53 tumor suppressor
9. Oncogenic forms of p53 inhibit p53-regulated gene expression
10. Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair
11. Regulation of p21WAF/Cip1 expression through mitogen-activated protein kinase signaling pathway
12. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21cip1
13. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
14. Induction of WAF1/CIP1 by p53-independent pathway
15. Principles of CDK regulation
16. Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
17. Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity
18. Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells
19. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes
20. The difference in immunogenicity among the regions of hepatitis C virus nonstructural protein NS3
21. p21 is a universal inhibitor of cyclin kinases
22. Critical point mutations for hepatitis C virus NS3 proteinase
23. Regulation of p21WAF1/CIP1 expression by p53-independent pathway