-
1
-
-
0034723055
-
Human genomics and obesity: Finding appropriate drug targets
-
Ravussin E, Bouchard C: Human genomics and obesity: finding appropriate drug targets. Eur J Pharmacol 410:131-145, 2000
-
(2000)
Eur J Pharmacol
, vol.410
, pp. 131-145
-
-
Ravussin, E.1
Bouchard, C.2
-
2
-
-
0032696042
-
Recent advances in basic obesity research
-
Yanovski JA, Yanovski SZ: Recent advances in basic obesity research. JAMA 282:1504-1506, 1999
-
(1999)
JAMA
, vol.282
, pp. 1504-1506
-
-
Yanovski, J.A.1
Yanovski, S.Z.2
-
3
-
-
0031931430
-
Dietary fat and obesity: An epidemiologic perspective
-
Seidell JC: Dietary fat and obesity: an epidemiologic perspective (Review). Am J Clin Nutr 67:5468-5508, 1998
-
(1998)
Am J Clin Nutr
, vol.67
, pp. 5468-5508
-
-
Seidell, J.C.1
-
4
-
-
0001187812
-
From the Reaktionsnorm to the adaptive norm: The norm of reaction, 1909-1960
-
Sarkar S: From the Reaktionsnorm to the adaptive norm: the norm of reaction, 1909-1960. Biology and Philosophy 14:235-252, 1999
-
(1999)
Biology and Philosophy
, vol.14
, pp. 235-252
-
-
Sarkar, S.1
-
7
-
-
0037417725
-
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content
-
Finck BN, Han X, Courtois M, Almond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP: A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc Natl Acad Sci U S A 100:1226-1231, 2003
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1226-1231
-
-
Finck, B.N.1
Han, X.2
Courtois, M.3
Almond, F.4
Nerbonne, J.M.5
Kovacs, A.6
Gross, R.W.7
Kelly, D.P.8
-
8
-
-
0346739933
-
Fatty acid binding protein-2 gene variants and insulin resistance: Gene and gene-environment interaction effects
-
Weiss EP, Brown MD, Shuldiner AR, Hagberg JM: Fatty acid binding protein-2 gene variants and insulin resistance: gene and gene-environment interaction effects. Physiol Genomics 10:145-157, 2002
-
(2002)
Physiol Genomics
, vol.10
, pp. 145-157
-
-
Weiss, E.P.1
Brown, M.D.2
Shuldiner, A.R.3
Hagberg, J.M.4
-
10
-
-
0035123646
-
Evidence for gene-nutrient interaction at the PPAR-γ locus
-
Luan J, Browne PO, Harding AH, Halsall DJ, O'Rahilly S, Chatterjee VK, Wareham NJ: Evidence for gene-nutrient interaction at the PPAR-γ locus. Diabetes 50:686-689, 2001
-
(2001)
Diabetes
, vol.50
, pp. 686-689
-
-
Luan, J.1
Browne, P.O.2
Harding, A.H.3
Halsall, D.J.4
O'Rahilly, S.5
Chatterjee, V.K.6
Wareham, N.J.7
-
11
-
-
0037195149
-
Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: Evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study
-
Ordovas JM, Corella D, Demissie S, Cupples LA, Couture P, Coltell O, Wilson PW, Schaefer EJ, Tucker KL: Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study. Circulation 106:2315-2321, 2002
-
(2002)
Circulation
, vol.106
, pp. 2315-2321
-
-
Ordovas, J.M.1
Corella, D.2
Demissie, S.3
Cupples, L.A.4
Couture, P.5
Coltell, O.6
Wilson, P.W.7
Schaefer, E.J.8
Tucker, K.L.9
-
12
-
-
0242410130
-
Dietary fat interacts with the -514C>T polymorphism in the hepatic lipase gene promoter on plasma lipid profiles in a multiethnic Asian population: The 1998 Singapore National Health Survey
-
Tai ES, Corella D, Deurenberg-Yap M, Cutter J, Chew SK, Tan CE, Ordovas JM: Dietary fat interacts with the -514C>T polymorphism in the hepatic lipase gene promoter on plasma lipid profiles in a multiethnic Asian population: the 1998 Singapore National Health Survey. J Nutr 133:3399-3408, 2003
-
(2003)
J Nutr
, vol.133
, pp. 3399-3408
-
-
Tai, E.S.1
Corella, D.2
Deurenberg-Yap, M.3
Cutter, J.4
Chew, S.K.5
Tan, C.E.6
Ordovas, J.M.7
-
13
-
-
0029837733
-
Panning for gold: Genome-wide scanning for linkage in type 1 diabetes
-
Todd JA, Farrall M: Panning for gold: genome-wide scanning for linkage in type 1 diabetes (Review). Hum Mol Genet 5:1443-1448, 1996
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1443-1448
-
-
Todd, J.A.1
Farrall, M.2
-
14
-
-
0032697493
-
The spread of the obesity epidemic in the United States, 1991-1998
-
Mokdad AH, Serdula MK, Dietz WH, Bowman BA, Marks JS, Koplan JP: The spread of the obesity epidemic in the United States, 1991-1998. JAMA 282:1519-1522, 1999
-
(1999)
JAMA
, vol.282
, pp. 1519-1522
-
-
Mokdad, A.H.1
Serdula, M.K.2
Dietz, W.H.3
Bowman, B.A.4
Marks, J.S.5
Koplan, J.P.6
-
15
-
-
0030984073
-
Mapping of mouse obesity genes: A generic approach to a complex trait
-
Fisler JS, Warden CH: Mapping of mouse obesity genes: a generic approach to a complex trait (Review). J Nutr 127:19098-19168, 1997
-
(1997)
J Nutr
, vol.127
, pp. 19098-19168
-
-
Fisler, J.S.1
Warden, C.H.2
-
16
-
-
0000033352
-
Analysis of quantitative inheritance of body size in mice. I. Hybridization and maternal influence
-
Chai C: Analysis of quantitative inheritance of body size in mice. I. Hybridization and maternal influence. Genetics 41:157-164, 1956
-
(1956)
Genetics
, vol.41
, pp. 157-164
-
-
Chai, C.1
-
17
-
-
0000033351
-
Analysis of quantitative inheritance of body size in mice. II. Gene action and segregation
-
Chai C: Analysis of quantitative inheritance of body size in mice. II. Gene action and segregation. Genetics 41:165-178, 1956
-
(1956)
Genetics
, vol.41
, pp. 165-178
-
-
Chai, C.1
-
18
-
-
0029918703
-
Quantitative trait loci for murine growth
-
Cheverud JM, Routman EJ, Duarte FA, van Swinderen B, Cothran K, Perel C: Quantitative trait loci for murine growth. Genetics 142:1305-1319, 1996
-
(1996)
Genetics
, vol.142
, pp. 1305-1319
-
-
Cheverud, J.M.1
Routman, E.J.2
Duarte, F.A.3
Van Swinderen, B.4
Cothran, K.5
Perel, C.6
-
19
-
-
0033564993
-
Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains
-
Cheverud JM, Pletscher LS, Vaughn TT, Marshall B: Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol Genomics 1:33-39, 1999
-
(1999)
Physiol Genomics
, vol.1
, pp. 33-39
-
-
Cheverud, J.M.1
Pletscher, L.S.2
Vaughn, T.T.3
Marshall, B.4
-
20
-
-
1542545179
-
Diet, obesity, and hyperglycemia in LG/J and SM/J mice
-
Ehrich TH, Kenney JP, Vaughn TT, Pletscher LS, Cheverud JM: Diet, obesity, and hyperglycemia in LG/J and SM/J mice. Obes Res 11:1400-1410, 2003
-
(2003)
Obes Res
, vol.11
, pp. 1400-1410
-
-
Ehrich, T.H.1
Kenney, J.P.2
Vaughn, T.T.3
Pletscher, L.S.4
Cheverud, J.M.5
-
21
-
-
4644244736
-
Genetic evidence for discordance between obesity and diabetes-related traits in the LGXSM recombinant inbred mouse strains
-
Cheverud JM, Ehrich TH, Kenney JP, Pletscher LS, Semenkovich CF: Genetic evidence for discordance between obesity and diabetes-related traits in the LGXSM recombinant inbred mouse strains. Diabetes 53:2700-2708, 2004
-
(2004)
Diabetes
, vol.53
, pp. 2700-2708
-
-
Cheverud, J.M.1
Ehrich, T.H.2
Kenney, J.P.3
Pletscher, L.S.4
Semenkovich, C.F.5
-
22
-
-
0035145192
-
Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice
-
Cheverud JM, Vaughn TT, Pletscher LS, Peripato AC, Adams ES, Erikson CF, King-Ellison KJ: Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice. Mamm Genome 12:3-12, 2001
-
(2001)
Mamm Genome
, vol.12
, pp. 3-12
-
-
Cheverud, J.M.1
Vaughn, T.T.2
Pletscher, L.S.3
Peripato, A.C.4
Adams, E.S.5
Erikson, C.F.6
King-Ellison, K.J.7
-
23
-
-
0028803358
-
Advanced intercross lines, an experimental population for fine genetic mapping
-
Darvasi A, Soller M: Advanced intercross lines, an experimental population for fine genetic mapping. Genetics 141:1199-1207, 1995
-
(1995)
Genetics
, vol.141
, pp. 1199-1207
-
-
Darvasi, A.1
Soller, M.2
-
24
-
-
0000604646
-
Genetics of body size and related characters. I. Selection of small and large races of the laboratory mouse
-
MacArthur J: Genetics of body size and related characters. I. Selection of small and large races of the laboratory mouse. Am Nat 78:142-157, 1944
-
(1944)
Am Nat
, vol.78
, pp. 142-157
-
-
MacArthur, J.1
-
25
-
-
0000357103
-
A study of the inheritance of body weight in the albino mouse by selection
-
Goodale H: A study of the inheritance of body weight in the albino mouse by selection. J Hered 29:101-112, 1938
-
(1938)
J Hered
, vol.29
, pp. 101-112
-
-
Goodale, H.1
-
26
-
-
13344287050
-
A comprehensive genetic map of the mouse genome
-
Dietrich WF, Miller J, Steen R, Merchant MA, Damron-Boles D, Husain Z, Dredge R, Daly MJ, Ingalls KA, O'Connor TJ: A comprehensive genetic map of the mouse genome. Nature 380:149-152, 1996
-
(1996)
Nature
, vol.380
, pp. 149-152
-
-
Dietrich, W.F.1
Miller, J.2
Steen, R.3
Merchant, M.A.4
Damron-Boles, D.5
Husain, Z.6
Dredge, R.7
Daly, M.J.8
Ingalls, K.A.9
O'Connor, T.J.10
-
27
-
-
0023426747
-
MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
-
Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newburg L: MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1:174-181, 1987
-
(1987)
Genomics
, vol.1
, pp. 174-181
-
-
Lander, E.S.1
Green, P.2
Abrahamson, J.3
Barlow, A.4
Daly, M.J.5
Lincoln, S.E.6
Newburg, L.7
-
28
-
-
0003414340
-
-
Boston, MA, Whitehead Institute
-
Lincoln S, Daly M, Lander E: Constructing genetic maps with MAPMAKER/EXP 3.0. Boston, MA, Whitehead Institute, 1992
-
(1992)
Constructing Genetic Maps with MAPMAKER/EXP 3.0
-
-
Lincoln, S.1
Daly, M.2
Lander, E.3
-
29
-
-
0024508964
-
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps
-
Lander ES, Botstein D: Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185-199, 1989
-
(1989)
Genetics
, vol.121
, pp. 185-199
-
-
Lander, E.S.1
Botstein, D.2
-
30
-
-
0027976724
-
-
published erratum appears
-
published erratum appears in Genetics 136:705, 1994
-
(1994)
Genetics
, vol.136
, pp. 705
-
-
-
31
-
-
0033394504
-
Mapping quantitative trait loci for murine growth: A closer look at genetic architecture
-
Vaughn TT, Pletscher LS, Peripato A, King-Ellison K. Adams E, Erikson C, Cheverud JM: Mapping quantitative trait loci for murine growth: a closer look at genetic architecture. Genet Res 74:313-322, 1999
-
(1999)
Genet Res
, vol.74
, pp. 313-322
-
-
Vaughn, T.T.1
Pletscher, L.S.2
Peripato, A.3
King-Ellison, K.4
Adams, E.5
Erikson, C.6
Cheverud, J.M.7
-
32
-
-
0000945228
-
Linear models III: General linear models
-
Chicago, SPSS
-
Wilkinson L, Coward M: Linear models III: General linear models. In SYSTAT 8.0: Statistics, Chicago, SPSS, 1998, p. 457-516
-
(1998)
SYSTAT 8.0: Statistics
, pp. 457-516
-
-
Wilkinson, L.1
Coward, M.2
-
33
-
-
0003352363
-
The genetic architecture of pleiotropic relations and differential epistasis
-
Wagner GP, Ed. San Diego, CA, Academic Press
-
Cheverud JM: The genetic architecture of pleiotropic relations and differential epistasis. In The Character Concept in Evolutionary Biology. Wagner GP, Ed. San Diego, CA, Academic Press, 2001, p. 411-434
-
(2001)
The Character Concept in Evolutionary Biology
, pp. 411-434
-
-
Cheverud, J.M.1
-
35
-
-
33646942472
-
A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
-
Haley CS, Knott SA: A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69:315-324, 1992
-
(1992)
Heredity
, vol.69
, pp. 315-324
-
-
Haley, C.S.1
Knott, S.A.2
-
37
-
-
0000135239
-
Correlations, similarities, and distance measures
-
Wilkinson L, Ed. Chicago, SPSS Science Marketing Department
-
Wilkinson L, Engelman L, Marcantonio R: Correlations, similarities, and distance measures. In SYSTAT 10: Statistics I. Wilkinson L, Ed. Chicago, SPSS Science Marketing Department, 2000, p. I-115-I-146
-
(2000)
SYSTAT 10: Statistics I
-
-
Wilkinson, L.1
Engelman, L.2
Marcantonio, R.3
-
39
-
-
0028224156
-
Precision mapping of quantitative trait loci
-
Zeng ZB: Precision mapping of quantitative trait loci. Genetics 136:1457-1468, 1994
-
(1994)
Genetics
, vol.136
, pp. 1457-1468
-
-
Zeng, Z.B.1
-
40
-
-
0034781050
-
A simple correction for multiple comparisons in interval mapping genome scans
-
Cheverud JM: A simple correction for multiple comparisons in interval mapping genome scans. Heredity 87:52-58, 2001
-
(2001)
Heredity
, vol.87
, pp. 52-58
-
-
Cheverud, J.M.1
-
41
-
-
0035026704
-
Predicting deleterious amino acid substitutions
-
Ng PC, Henikoff S: Predicting deleterious amino acid substitutions. Genome Res 11:863-874, 2001
-
(2001)
Genome Res
, vol.11
, pp. 863-874
-
-
Ng, P.C.1
Henikoff, S.2
-
42
-
-
0027968068
-
CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson JD, Higgins DG, Gibson TJ: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acid Res 22:4673-4680, 1996
-
(1996)
Nucleic Acid Res
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
43
-
-
0033180115
-
Cloning, sequencing, expression, and purification of the C isozyme of mouse phosphofructokinase
-
Gunasekera D, Kemp RG: Cloning, sequencing, expression, and purification of the C isozyme of mouse phosphofructokinase. Protein Expr Purif 16:448-453, 1999
-
(1999)
Protein Expr Purif
, vol.16
, pp. 448-453
-
-
Gunasekera, D.1
Kemp, R.G.2
-
44
-
-
1642575964
-
Identification of C-terminal motifs responsible for transmission of inhibition by ATP of mammalian phosphofructokinase, and their contribution to other allosteric effects
-
Martinez-Costa OH, Hermida C, Sanchez-Martinez C, Santamaria B, Aragon JJ: Identification of C-terminal motifs responsible for transmission of inhibition by ATP of mammalian phosphofructokinase, and their contribution to other allosteric effects. Biochem J 377:77-84, 2004
-
(2004)
Biochem J
, vol.377
, pp. 77-84
-
-
Martinez-Costa, O.H.1
Hermida, C.2
Sanchez-Martinez, C.3
Santamaria, B.4
Aragon, J.J.5
-
45
-
-
0342656636
-
Phosphofructokinase C isozyme from ascites tumor cells: Cloning, expression, and properties
-
Sanchez-Martinez C, Estevez AM, Aragon JJ: Phosphofructokinase C isozyme from ascites tumor cells: cloning, expression, and properties. Biochem Biophys Res Commun 271:635-640, 2000
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 635-640
-
-
Sanchez-Martinez, C.1
Estevez, A.M.2
Aragon, J.J.3
-
46
-
-
2942687834
-
Adiponectin: A novel adipokine linking adipocytes and vascular function
-
Goldstein BJ, Scalia R: Adiponectin: a novel adipokine linking adipocytes and vascular function. J Clin Endocrinol Metab 89:2563-2568, 2004
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2563-2568
-
-
Goldstein, B.J.1
Scalia, R.2
-
47
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
Browning JD, Horton JD: Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 114:147-152, 2004
-
(2004)
J Clin Invest
, vol.114
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
48
-
-
0031034366
-
Contribution of energy intake and tissue enzymatic profile to body weight gain in high-fat-fed rats
-
Gayles EC, Pagliasotti MJ, Prach PA, Koppenhafer TA, Hill JO: Contribution of energy intake and tissue enzymatic profile to body weight gain in high-fat-fed rats. Am J Physiol 272:R188-R194, 1997
-
(1997)
Am J Physiol
, vol.272
-
-
Gayles, E.C.1
Pagliasotti, M.J.2
Prach, P.A.3
Koppenhafer, T.A.4
Hill, J.O.5
-
49
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ: Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A 100:8466-8471, 2003
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
50
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI: Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350:664-671, 2004
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
51
-
-
1442339091
-
Causation of type 2 diabetes: The Gordian knot unravels
-
Taylor R: Causation of type 2 diabetes: the Gordian knot unravels. N Engl J Med 350:639-641, 2004
-
(2004)
N Engl J Med
, vol.350
, pp. 639-641
-
-
Taylor, R.1
-
52
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB, Shulman GI: Mitochondrial dysfunction and type 2 diabetes. Science 307:384-387, 2005
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
|