Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice

Mammalian Genome

Volumn 12, Issue 1, 2001, Pages 3-12

  Cheverud, James M ^a   Vaughn, Ty T ^a   Pletscher, L Susan ^a   Peripato, Andrea C ^a   Adams, Emily S ^a   Erikson, Christopher F ^a   King Ellison, Kelly J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY SIZE; BODY WEIGHT; CONTROLLED STUDY; EPISTASIS; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HYBRID; INBRED STRAIN; MULTIGENE FAMILY; NONHUMAN; OBESITY; PHENOTYPE; QUANTITATIVE TRAIT; TAIL;

ADIPOSE TISSUE; ALLELES; ANIMALS; BODY CONSTITUTION; BODY WEIGHT; CROSSES, GENETIC; EPISTASIS, GENETIC; FEMALE; GENOTYPE; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED STRAINS; MICROSATELLITE REPEATS; OBESITY; QUANTITATIVE TRAIT, HERITABLE; TAIL; VARIATION (GENETICS);

ANIMALIA;

EID: 0035145192     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003350010218     Document Type: Article

References (75)

1. Genetics of body-weight regulation
2. Detection of QTL for body weight and body fat content in mice using genetic markers
3. Quantitative trait loci affecting body weight and fatness from a mouse line selected for extreme high growth
4. Analysis of quantitative inheritance of body size in mice. I. Hybridization and maternal influence
5. Analysis of quantitative inheritance of body size in mice. II. Gene action and segregation
6. Analysis of quantitative inheritance of body size in mice. III. Dominance
7. Analysis of quantitative inheritance of body size in mice. IV. An attempt to isolate polygenes
8. Analysis of quantitative inheritance of body size in mice. V. Effects of small numbers of polygenes on similar genetic backgrounds
9. Detecting epistasis among quantitative trait loci
10. The genetic architecture of pleiotropic relations and differential epistasis
11. Epistasis and its contribution to genetic variance components
12. Epistasis as a source of increased additive genetic variance at population bottlenecks
13. Methods for the comparative analysis of variation patterns
14. Quantitative trait loci for murine growth
15. Pleiotropic effects of individual gene loci on mandibular morphology
16. Epistasis and the evolution of additive genetic variance in populations that pass through a bottleneck
17. Permanency of response to selection for quantitative characters in finite populations
18. A genetic map of the mouse suitable for typing intraspecific crosses
19. A comprehensive genetic map of the mouse genome
20. Mapping of body weight loci on mouse chromosome X
21. Uncoupling protein 2: A novel gene linked to obesity and hyperinsulinemia
22. A study of the inheritance of body weight in the albino mouse by selection
23. Progress report on possibilities in progeny test breeding
24. Multiple comparisons, explained
25. On the effect of founder events on epistatic genetic variance
26. Epistasis and the effect of founder events on the additive genetic variance
27. Epistasis and the increase in additive genetic variance: Implications for phase I of Wright's shifting balance process
28. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
29. A genetic map of quantitative trait loci for body weight in the mouse
30. Identification of quantitative trait loci for prolificacy and growth in mice
31. Identification and characterization of the mouse obesity gene tubby: A member of a novel gene family
32. Genetic variation in body weight growth and composition in the intercross of Large (LG/J) and Small (SM/J) inbred strains of mice
33. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
34. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
35. MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations
36. Quantitative trait loci for early and late developing skull characters in mice: A test of the genetic independence model of morphological integration
37. Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q
38. Constructing Genetic Maps with MAPMAKER/EXP 3.0
39. Genetics of body size and related characters. I. Selection of small and large races of the laboratory mouse
40. Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model
41. Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice
42. The human gene obesity map: The 1998 update
43. Genetic dissection of obesity in polygenic animal models
44. Mapping quantitative trait loci for body weight on the X chromosome in mice. I. Analysis of a reciprocal F2 population
45. Mapping quantitative trait loci for body weight on the X chromosome in mice. II. Analysis of congenic backcrosses
46. CAT scans, PET scans, and genomic scans
47. A rapid method of scoring simple sequence repeat polymorphisms with agarose gel electrophoresis
48. Polymorphism for PCR-analyzed microsatellites: Data for two additional inbred mouse strains and the utility of agarose gel electrophoresis
49. Gene effects on a quantitative trait: Two-locus epistatre effects measured at microsatellite markers and at estimated QTL
50. Multiple comparisons and related issues in the interpretation of epidemiologic data
51. A building block model for quantitative genetics
52. Detection of obesity QTLs on mouse chromosomes 1 and 7 by selective DNA pooling
53. Obesity QTLs on mouse chromosomes 2 and 17
54. Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain
55. Invited commentary: Re: "Multiple comparisons and related issues in the interpretation of epidemiologic data"
56. The philosophy of multiple comparisons
57. Mapping quantitative trait loci for murine growth - A closer look at genetic architecture
58. UCP3: An uncoupling protein homolog expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
59. Perspective: The theories of Fisher and Wright in the context of metapopulations: When nature does many small experiments
60. On the eigenvalue distribution of genetic and phenotypic dispersion matrices: Evidence for a nonrandom organization of quantitative character variation
61. Identification of four chromosomal loci determining obesity in a multifactorial mouse model
62. A new approach to the problem of multiple comparisons in the genetic dissection of complex traits
63. Dietary obesity linked to genetic loci on chromosomes 9 and 15
64. Genetics of dietary obesity in AKR/J X SWR/J mice: Segregation of the trait and identification of a linked locus on chromosome 4
65. Dietary obesity in the mouse: Interaction of strain with diet composition
66. Variance-induced peak shifts
67. Gene interaction affects the additive genetic variance in subdivided populations with migration and extinction
68. Sensitivity to dietary obesity linked to a locus on chromosome 15 in a Cast/Ei x C57BL/6J F2 intercross
69. 2 mice derived from an AKR/J x SWR/J cross
70. Gene-environment interaction: A significant diet-dependent obesity locus demonstrated in a congenic segment on mouse chromosome 7