Genetic evidence for discordance between obesity- and diabetes-related traits in the LGXSM recombinant inbred mouse strains

Diabetes

Volumn 53, Issue 10, 2004, Pages 2700-2708

  Cheverud, James M ^a   Ehrich, Thomas H ^a   Kenney, Jane P ^a   Pletscher, L Susan ^a   Semenkovich, Clay F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; LEPTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY GROWTH; CONTROLLED STUDY; CORRELATION FUNCTION; DIABETES MELLITUS; FAT INTAKE; FEMALE; GLUCOSE BLOOD LEVEL; INBRED STRAIN; INSULIN BLOOD LEVEL; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL;

ANIMALS; DIABETES MELLITUS; DIET; DIETARY CARBOHYDRATES; DIETARY FATS; FEMALE; MALE; MICE; MICE, INBRED STRAINS; OBESITY; RECOMBINATION, GENETIC; SEX CHARACTERISTICS;

EID: 4644244736     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.10.2700     Document Type: Article

References (23)

1. Mokdad AH, Ford ES, Bowman BA, Dietz WH, Vinicor F, Bales VS, Marks JS: Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 289:76-79, 2003
2. Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH: The disease burden associated with overweight and obesity. JAMA 282:1523-1529, 1999
3. Snyder EE, Walts B, Perusse L, Chagnon YC, Weisnagel SJ, Rankinen T, Bouchard C: The human obesity gene map: the 2003 update. Obes Res 12:369-439, 2004
4. Yanovski JA, Yanovski SZ: Recent advances in basic obesity research. JAMA 282:1504-1506, 1999
5. Seidell JC: Dietary fat and obesity: an epidemiologic perspective. Am J Clin Nutr 67:546S-550S, 1998
6. Bouchard C: Genetics of human obesities: introductory notes. In The Genetics of Obesity. Bouchard C, Ed. Boca Raton, FL, CRC Press, 1994
7. Fisler JS, Warden CH: Mapping of mouse obesity genes: a generic approach to a complex trait. J Nutr 127:1909S-1916S, 1997
8. Comuzzie AG: The emerging pattern of genetic contribution to human obesity. Best Pract Res Clin Endocrinol Metab 16:611-621, 2002
9. Cheverud JM, Routman EJ, Duarte FM, van Swinderen B, Cothran K, Perel C: Quantitative trait loci for murine growth. Genetics 142:1305-1319, 1996
10. Cheverud JM, Vaughn TT, Pletscher LS, Peripato AC, Adams ES, Erikson CF, King-Ellison KJ: Genetic architecture of adiposity in the cross of LG/J and SM/J inbred mice. Mamm Genome 12:3-12, 2001
11. Vaughn TT, Pletscher LS, Peripato A, King-Ellison K, Adams E, Erikson C, Cheverud JM: Mapping quantitative trait loci for murine growth: a closer look at genetic architecture. Genet Res 74:313-322, 1999
12. Cheverud JM, Pletscher LS, Vaughn TT, Marshall B: Differential response to dietary fat in large (LG/J) and small (SM/J) inbred mouse strains. Physiol Genomics 1:33-39, 1999
13. Ehrich TH, Kenney JP, Vaughn TT, Pletscher LS, Cheverud JM: Diet, obesity, and hyperglycemia in LG/J and SM/J Mice. Obes Res 11:1400-1410, 2003
14. Darvasi A, Soller M: Advanced intercross lines, an experimental population for fine genetic mapping. Genetics 141:1199-1207, 1995
15. Silver L: Mouse Genetics. Oxford, U.K., Oxford University Press, 1995
16. Goodale H: A study of the inheritance of body weight in the albino mouse by selection. J Heredity 29:101-112, 1938
17. MacArthur J: Genetics of body size and related characters. I. Selection of small and large races of the laboratory mouse. Am Naturalist 78:142-157, 1944
18. Chai CK: Analysis of quantitative inheritance of body size in mice. II. Gene action and segregation. Genetics 41:167-178, 1956
19. Cheverud JM: Genetic architecture of quantitative variation. In Evolutionary Genetics: Concepts and Case Studies. Fox CW, Wolf JB, Eds. Oxford University Press, Oxford, 2005
20. Sokal RS, Rohlf FJ: Biometry. New York, W.H. Freeman, 1995
21. Falconer DS, Mackay T: Introduction to Quantitative Genetics. New York, John Wiley and Sons, 1997
22. Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 395:763-770, 1998
23. Kramer MG, Vaughn TT, Pletscher LS, King-Ellison K, Adams E, Erickson C, Cheverud JM: Genetic variation in body weight growth and composition in the intercross of large (LG/J) and small (SM/J) inbred strains of mice. Genet Molecular Biol 21:211-218, 1998