BRCTx is a novel, highly conserved RAD18-interacting protein

Molecular and Cellular Biology

Volumn 25, Issue 2, 2005, Pages 779-788

  Adams, David J ^a   Van Der Weyden, Louise ^a   Gergely, Fanni V ^b   Arends, Mark J ^c   Bee, Ling Ng ^a   Tannahill, David ^a   Kanaar, Roland ^d   Markus, Andrea ^e   Morris, Brian J ^e   Bradley, Allan ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN BRCTX; PROTEIN RAD 18; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL GROWTH; CELLULAR DISTRIBUTION; CENTROSOME; CLONING; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEMALE; FERTILITY; HISTOPATHOLOGY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; INTERPHASE; MALE; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; TESTIS;

ANIMALIA; MURINAE; RODENTIA;

EID: 19944426586     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.2.779-788.2005     Document Type: Article

References (40)

1. Adams, D. J., L. van der Weyden, A. Mayeda, S. Stamm, B. J. Morris, and J. E. Rasko. 2001. ZNF265: a novel spliceosomal protein able to induce alternative splicing. J. Cell Biol. 154:25-32.
2. Adams, D. J., D. J. Beveridge, L. van der Weyden, H. Mangs, P. J. Leedman, and B. J. Morris. 2003. HADHB, HuR, and CP1 bind to the distal 3′-untranslated region of human renin mRNA and differentially modulate renin expression. J. Biol. Chem. 278:44894-44903.
3. Birney, E., D. Andrews, P. Bevan, M. Caccamo, G. Cameron, Y. Chen, L. Clarke, G. Coates, T. Cox, J. Cuff, V. Curwen, T. Cutts, T. Down, R. Durbin, E. Eyras, X. M. Fernandez-Suarez, P. Gane, B. Gibbins, J. Gilbert, M. Hammond, H. Hotz, V. Iyer, A. Kahari, K. Jekosch, A. Kasprzyk, D. Keefe, S. Keenan, H. Lehvaslaiho, G. McVicker, C. Melsopp, P. Meidl, E. Mongin, R. Pettett, S. Potter, G. Proctor, M. Rae, S. Searle, G. Slater, D. Smedley, J. Smith, W. Spooner, A. Stabenau, J. Stalker, R. Storey, A. Ureta-Vidal, C. Woodwark, M. Clamp, and T. Hubbard. 2004. Ensembl 2004. Nucleic Acids Res. 32(Database Issue):D468-D470.
4. Bork, P., K. Hofmann, P. Bucher, A. F. Neuwald, S. F. Altschul, and E. V. Koonin. 1997. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J. 11:68-76.
5. de Boer, J., J. O. Andressoo, J. de Wit, J. Huijmans, R. B. Beems, H. van Steeg, G. Weeda, G. T. van der Horst, W. van Leeuwen, A. P. Themmen, M. Meradji, and J. H. Hoeijmakers. 2002. Premature aging in mice deficient in DNA repair and transcription. Science 296:1276-1279.
6. Essers, J., A. B. Houtsmuller, L. van Veelen, C. Paulusma, A. L. Nigg, A. Pastink, W. Vermeulen, J. H. Hoeijmakers, and R. Kanaar. 2002. Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J. 21:2030-2037.
7. Gray, J. W., and Z. Darzynkiewicz. 1987. Techniques in cell cycle analysis. Humana Press, London, England.
8. Hakem, R., J. L. de la Pompa, C. Sirard, R. Mo, M. Woo, A. Hakem, A. Wakeham, J. Potter, A. Reitmair, F. Billia, E. Firpo, C. C. Hui, J. Roberts, J. Rossant, and T. W. Mak. 1996. The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell 85:1009-1023.
9. Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
10. Jain, A. N., K. Chin, A. L. Borresen-Dale, B. K. Erikstein, P. Eynstein Lonning, R. Kaaresen, and J. W. Gray. 2001. Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival. Proc. Natl. Acad. Sci. USA 98: 7952-7957.
11. James, P., J. Halladay, and E. A. Craig. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425-1436.
12. Kang, J., R. T. Bronson, and Y. Xu. 2002. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J. 21:1447-1455.
13. Kunapuli, P., R. Somerville, I. H. Still, and J. K. Cowell. 2003. ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins. Oncogene 22:3417-3423.
14. Luo, G., I. M. Santoro, L. D. McDaniel, I. Nishijima, M. Mills, H. Youssoufian. H. Vogel, R. A. Schultz, and A. Bradley. 2000. Cancer predisposition caused by elevated mitotic recombination in Bloom mice. Nat. Genet. 26:424-429.
15. Maclean, K. H., U. B. Keller, C. Rodriguez-Galindo, J. A. Nilsson, and J. L. Cleveland. 2003. c-Myc augments gamma irradiation-induced apoptosis by suppressing Bel-XL. Mol. Cell. Biol. 23:7256-7270.
16. Manke, I. A., D. M. Lowery, A. Nguyen, and M. B. Yaffe. 2003. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 302:636-639.
17. Mendes-da-Silva, P., A. Moreira, J. Duro-da-Costa, D. Matias, and C. Monteiro. 2000. Frequent loss of heterozygosity on chromosome 5 in non-small cell lung carcinoma. Mol. Pathol. 53:184-187.
18. Miki, Y., J. Swensen, D. Shattuck-Eidens, P. A. Futreal, K. Harshman, S. Tavtigian, Q. Liu, C. Cochran, L. M. Bennett, W. Ding, et al. 1994. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266:66-71.
19. Mills, A. A., B. Zheng, X. J. Wang, H. Vogel, D. R. Roop, and A. Bradley. 1999. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398:708-713.
20. Morales, J. C., Z. Xia, T. Lu, M. B. Aldrich, B. Wang, C. Rosales, R. E. Kellems, W. N. Hittelman, S. J. Elledge, and P. B. Carpenter. 2003. Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J. Biol. Chem. 278:14971-14977.
21. Moynahan, M. E. 2002. The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans. Oncogene 21:8994-9007.
22. Mulder, L. C., L. A. Chakrabarti, and M. A. Muesing. 2002. Interaction of HIV-1 integrase with DNA repair protein hRad18. J. Biol. Chem. 277: 27489-27493.
23. Nagy, A., M. Gertenstein, K. Vintersten, and R. Behringer 2003. Manipulating the mouse embryo: a laboratory manual, 3rd ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
24. Osoegawa, K., M. Tateno, P. Y. Woon, E. Frengen, A. G. Mammoser, J. J. Catanese, Y. Hayashizaki, and P. J. de Jong. 2000. Bacterial artificial chromosome libraries for mouse sequencing and functional analysis. Genome Res. 10:116-128.
25. Pachnis, V., C. I. Brannan, and S. M. Tilghman. 1988. The structure and expression of a novel gene activated in early mouse embryogenesis. EMBO J. 7:673-681.
26. Ramirez-Solis, R., P. Liu, and A. Bradley. 1995. Chromosome engineering in mice. Nature 378:720-724.
27. Richter, J., U. Wagner, P. Schraml, R. Maurer, G. Alund, H. Knonagel, H. Moch, M. J. Mihatsch, T. C. Gasser, and G. Sauter. 1999. Chromosomal imbalances are associated with a high risk of progression in early invasive (pT1) urinary bladder cancer. Cancer Res. 59:5687-5691.
28. Sharan, S. K., M. Morimatsu, U. Albrecht, D. S. Lim, E. Regel, C. Dinh, A. Sands, G. Eichele, P. Hasty, and A. Bradley. 1997. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2. Nature 386:804-810.
29. Shin, S., and I. M. Verma. 2003. BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription. Proc. Natl. Acad. Sci. USA 100:7201-7206.
30. Shirozu, M., T. Nakano, J. Inazawa, K. Tashiro, H. Tada, T. Shinohara, and T. Honjo. 1995. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics 28:495-500.
31. Smith, K. G., U. Weiss, K. Rajewsky, G. J. Nossal, and D. M. Tarlinton. 1994. Bcl-2 increases memory B-cell recruitment but does not perturb selection in germinal centers. Immunity 1:803-813.
32. Tateishi, S., H. Niwa, J. Miyazaki, S. Fujimoto, H. Inoue, and M. Yamaizumi. 2003. Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells. Mol. Cell. Biol. 23:474-481.
33. Tsao, S. W., N. Wong, X. Wang, Y. Liu, T. S. Wan, L. F. Fung, W. D. Lancaster, L. Gregoire, and Y. C. Wong. 2001. Nonrandom chromosomal imbalances in human ovarian surface epithelial cells immortalized by HPV16-E6E7 viral oncogenes. Cancer Genet. Cytogenet. 130:141-149.
34. Turner, J., and M. Crossley. 1998. Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators. EMBO J. 17:5129-5140.
35. Venkitaraman, A. R. 2003. A growing network of cancer-susceptibility genes. N. Engl. J. Med. 348:1917-1919.
36. Ward, I. M., K. Minn, J. van Deursen, and J. Chen. 2003. p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol. Cell. Biol. 23:2556-2563.
37. Williams, B. R., O. K. Mirzoeva, W. F. Morgan, J. Lin, W. Dunnick, and J. H. Petrini. 2002. A murine model of Nijmegen breakage syndrome. Curr. Biol. 12:648-653.
38. Wooster, R., G. Bignell, J. Lancaster, S. Swift, S. Seal, J. Mangion, N. Collins, S. Gregory, C. Gumbs, and G. Micklem. 1995. Identification of the breast cancer susceptibility gene BRCA2. Nature 378:789-792.
39. Watanabe, K., S. Tateishi, M. Kawasuji, T. Tsurimoto, H. Inoue, and M. Yamaizumi. 2004. Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J. 23:3886-3896.
40. Yu, X., C. C. Chini, M. He, G. Mer, and J. Chen. 2003. The BRCT domain is a phospho-protein binding domain. Science 302:639-642.