Behavioral and neurochemical effects of 5-{4-[4-(5-cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl}-benzofuran-2 -carboxamide (EMD 68843): A combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine1A receptor partial agonist

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 3, 2002, Pages 1220-1227

  Page, Michelle E ^a   Cryan, John F ^a   Sullivan, Arthur ^a   Dalvi, Ashutosh ^a   Saucy, Berangere ^a   Manning, David R ^a   Lucki, Irwin ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 8 HYDROXY 2 [N [N PROPYL N (39 IODO 29 PROPENYL)]]AMINOTETRALIN; FLUOXETINE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); PARTIAL AGONIST; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN UPTAKE INHIBITOR; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG; VILAZODONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG SELECTIVITY; FRONTAL CORTEX; HIPPOCAMPUS; MALE; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; SEROTONIN BLOOD LEVEL; SEROTONIN RELEASE;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; BENZOFURANS; BRAIN CHEMISTRY; CELL LINE; EXTRACELLULAR SPACE; FEMALE; FLUOXETINE; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); INDOLES; MICRODIALYSIS; PREFRONTAL CORTEX; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SEROTONIN UPTAKE INHIBITORS; SWIMMING;

EID: 0036720479     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.034280     Document Type: Article

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