Pharmacology of flibanserin

CNS Drug Reviews

Volumn 8, Issue 2, 2002, Pages 117-142

  Borsini, Franco ^a   Evans, Kennett ^b   Jason, Kathryn ^c   Rohde, Frank ^a   Alexander, Barbara ^a   Pollentier, Stephan ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b BOEHRINGER INGELHEIM CANADA LTD   (Canada)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Adenylyl cyclase; Animal models; Antidepressants; Dopamine; Firing rate; Flibanserin; Receptors; Serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ADENYLATE CYCLASE; ANTIDEPRESSANT AGENT; BUSPIRONE; DIAZEPAM; DOPAMINE; DOPAMINE 4 RECEPTOR; DOPAMINE 4 RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; FLIBANSERIN; FLUOXETINE; IMIPRAMINE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NORADRENALIN; OPIATE RECEPTOR; PINDOBIND; POSTSYNAPTIC RECEPTOR; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 7 RECEPTOR; TERTATOLOL; UNCLASSIFIED DRUG; ANXIOLYTIC AGENT; BENZIMIDAZOLE DERIVATIVE; DOPAMINE 2 RECEPTOR; DRD4 PROTEIN, HUMAN; NEUROLEPTIC AGENT; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR AFFECTING AGENT;

ANXIETY NEUROSIS; BRAIN CORTEX; BRAIN NERVE CELL; CONCENTRATION RESPONSE; DEPRESSION; DOPAMINE BRAIN LEVEL; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SENSITIVITY; DRUG SENSITIZATION; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MICROIONTOPHORESIS; NERVE CELL STIMULATION; NONHUMAN; NORADRENALIN BRAIN LEVEL; PSYCHOSIS; QUALITATIVE ANALYSIS; RECEPTOR AFFINITY; REVIEW; SEDATION; SEROTONIN BRAIN LEVEL; SEROTONIN METABOLISM; SOMNOLENCE; STRESS; ANIMAL; ANIMAL BEHAVIOR; ANIMAL MODEL; BRAIN; ELECTROPHYSIOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; BENZIMIDAZOLES; BRAIN; DOPAMINE AGENTS; ELECTROPHYSIOLOGY; HUMANS; MODELS, ANIMAL; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN AGENTS;

EID: 0036023385     PISSN: 1080563X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3458.2002.tb00219.x     Document Type: Review

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