β-Carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway

Neuropharmacology

Volumn 48, Issue 1, 2005, Pages 105-117

  Hans, Grégory ^a   Malgrange, Brigitte ^a   Lallemend, François ^a   Crommen, Jessica ^a   Wislet Gendebien, Sabine ^a   Belachew, Shibeshih ^a   Robe, Pierre ^a   Rogister, Bernard ^a   Moonen, Gustave ^a   Rigo, Jean Michel ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b HASSELT UNIVERSITY   (Belgium)

Author keywords

Carbolines; Apoptosis; Caspases; Cerebellar granule neurons; Mitochondrion

Indexed keywords

APOPTOSIS INDUCING FACTOR; BETA CARBOLINE DERIVATIVE; BONGKREKIC ACID; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOSPORIN A; CYTOCHROME C; N BUTYL BETA CARBOLINE 3 CARBOXYLATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; MITOCHONDRIAL MEMBRANE; MOLECULAR DYNAMICS; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; APOPTOSIS INDUCING FACTOR; ASTROCYTES; BENZIMIDAZOLES; BINDING SITES; BLOTTING, WESTERN; CARBOCYANINES; CARBOLINES; CASPASES; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYTOCHROMES C; DRUG INTERACTIONS; ETHIDIUM; FLAVOPROTEINS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; FORMAZANS; MEMBRANE PROTEINS; MITOCHONDRIA; NEURONS; RATS; TETRAZOLIUM SALTS; TIME FACTORS; TRITIUM;

EID: 19944368737     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.09.001     Document Type: Article

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