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Volumn 69, Issue 4, 1997, Pages 1382-1388

Involvement of a caspase-3-like cysteine protease in 1-methyl-4- phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons

Author keywords

Apoptosis; Caspase 3; Cell death; Cerebellar granule neurons; CPP32; Cytochrome c; Mitochondria; MPP+; Necrosis; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CYSTEINE PROTEINASE; CYTOCHROME C;

EID: 0030984429     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69041382.x     Document Type: Article
Times cited : (161)

References (49)
  • 2
    • 0007347574 scopus 로고    scopus 로고
    • Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging with reference to Parkinson's disease
    • Anglade P., Vyas S., Hirsch E. C., and Agid Y. (1997) Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging with reference to Parkinson's disease. Mov. Disord. 12, 4-10.
    • (1997) Mov. Disord. , vol.12 , pp. 4-10
    • Anglade, P.1    Vyas, S.2    Hirsch, E.C.3    Agid, Y.4
  • 3
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J. M., Orrenius E., Lipton S. A., and Nicotera P. (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15, 961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Orrenius, E.3    Lipton, S.A.4    Nicotera, P.5
  • 5
    • 0029940901 scopus 로고    scopus 로고
    • Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: Protection with antioxidants and glutamate receptor antagonists
    • Atabay C., Cagnoli C. M., Kharlamov E., Ikonomovic M. D., and Manev H. (1996) Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: protection with antioxidants and glutamate receptor antagonists. J. Neurosci. 43, 465-475.
    • (1996) J. Neurosci. , vol.43 , pp. 465-475
    • Atabay, C.1    Cagnoli, C.M.2    Kharlamov, E.3    Ikonomovic, M.D.4    Manev, H.5
  • 6
    • 0000620478 scopus 로고    scopus 로고
    • Keeping neurons alive: The molecular control of apoptosis
    • Bredesen D. E. (1996) Keeping neurons alive: the molecular control of apoptosis. Neuroscientist 2, 181-190.
    • (1996) Neuroscientist , vol.2 , pp. 181-190
    • Bredesen, D.E.1
  • 7
    • 0028915454 scopus 로고
    • Regulation of lymphocyte survival by the bcl-2 gene family
    • Cory S. (1995) Regulation of lymphocyte survival by the bcl-2 gene family. Annu. Rev. Immunol. 13, 513-543.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 513-543
    • Cory, S.1
  • 8
    • 0026345867 scopus 로고
    • Apoptosis and DNA degradation induced by 1-methyl-pyridinium in neurons
    • Dipasquale B., Marini A. M., and Youle R. J. (1991) Apoptosis and DNA degradation induced by 1-methyl-pyridinium in neurons. Biochem. Biophys. Res. Commun. 181, 1442-1448.
    • (1991) Biochem. Biophys. Res. Commun. , vol.181 , pp. 1442-1448
    • Dipasquale, B.1    Marini, A.M.2    Youle, R.J.3
  • 9
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari M., Talanian R. V., Wong W. W., and Nagata S. (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380, 723-726.
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 13
    • 84975751684 scopus 로고
    • Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
    • Hartley A., Stone J. M., Heron C., Cooper J. M., and Schapira A. H. V. (1994) Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J. Neurochem. 63, 1987-1990.
    • (1994) J. Neurochem. , vol.63 , pp. 1987-1990
    • Hartley, A.1    Stone, J.M.2    Heron, C.3    Cooper, J.M.4    Schapira, A.H.V.5
  • 15
    • 0025759279 scopus 로고
    • Different functional boundaries for the major antigenic region of two cytochromes c
    • Jemmerson R. and Johnson J. G. (1991) Different functional boundaries for the major antigenic region of two cytochromes c. Proc. Natl. Acad. Sci. USA 88, 4428-4432.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4428-4432
    • Jemmerson, R.1    Johnson, J.G.2
  • 16
    • 0003059548 scopus 로고    scopus 로고
    • Pathological evidence for oxidative stress
    • (Jenner P. and Olanow C. W., eds), Academic Press, San Diego
    • Jenner P. (1996) Pathological evidence for oxidative stress, in Parkinson's Disease and Related Degenerative Disorders (Jenner P. and Olanow C. W., eds), pp. 24-46. Academic Press, San Diego.
    • (1996) Parkinson's Disease and Related Degenerative Disorders , pp. 24-46
    • Jenner, P.1
  • 17
    • 0026087118 scopus 로고
    • A monoclonal antibody specific for a cytochrome c T cell stimulator peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells
    • Johnson J. G., Burrell E., Taylor P. S., and Jenkins M. K. (1991) A monoclonal antibody specific for a cytochrome c T cell stimulator peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells. Eur. J. Immunol. 21, 143-151.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 143-151
    • Johnson, J.G.1    Burrell, E.2    Taylor, P.S.3    Jenkins, M.K.4
  • 18
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck R. M., Bossy-Wetzel E., Green D. R., and Newmeyer D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Nature 275, 1132-1136.
    • (1997) Nature , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 20
    • 0031017075 scopus 로고    scopus 로고
    • Mitochondrial control of apoptosis
    • Kroemer G., Zamzami N., and Susin S. A. (1997) Mitochondrial control of apoptosis. Immunol. Today 18(1), 44-51.
    • (1997) Immunol. Today , vol.18 , Issue.1 , pp. 44-51
    • Kroemer, G.1    Zamzami, N.2    Susin, S.A.3
  • 21
  • 22
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine analog synthesis
    • Langston J. W., Ballard J. W., Tetrud J. W., and Irwin I. (1983) Chronic parkinsonism in humans due to a product of meperidine analog synthesis. Science 219, 979-980.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, J.W.2    Tetrud, J.W.3    Irwin, I.4
  • 23
    • 0028102478 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik Y. A., Kaufmann S. H., Desnoyers S., Poirier G. G., and Earnshaw W. C. (1994) Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371, 346-347.
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufmann, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 24
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
    • Liu X., Kim C. N., Yang J., Jemmerson R., and Wang X. (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86, 147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 25
    • 0025137923 scopus 로고
    • Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: Protection by synthetic derivatives of endogenous sphingolipids
    • Manev H., Favaron M., Vicini S., Guidotti A., and Costa E. (1990) Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids. J. Pharmacol. Exp. Ther. 252, 419-427.
    • (1990) J. Pharmacol. Exp. Ther. , vol.252 , pp. 419-427
    • Manev, H.1    Favaron, M.2    Vicini, S.3    Guidotti, A.4    Costa, E.5
  • 26
    • 0030897988 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of interleukin-1-β-converting enzyme and related caspases
    • Margolin N., Raybuck S. A., Wilson K. P., Chen W., Fox T., Gu Y., and Livingston D. J. (1997) Substrate and inhibitor specificity of interleukin-1-β-converting enzyme and related caspases. J. Biol. Chem. 272, 7223-7228.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7223-7228
    • Margolin, N.1    Raybuck, S.A.2    Wilson, K.P.3    Chen, W.4    Fox, T.5    Gu, Y.6    Livingston, D.J.7
  • 27
    • 0024439793 scopus 로고
    • The neurotoxicity of 1-methyl-4-pyridinium in cultured cerebellar granule neurons
    • Marini A. M., Schwartz J. P., and Kopin I. J. (1989) The neurotoxicity of 1-methyl-4-pyridinium in cultured cerebellar granule neurons. J. Neurosci. 9, 3665-3672.
    • (1989) J. Neurosci. , vol.9 , pp. 3665-3672
    • Marini, A.M.1    Schwartz, J.P.2    Kopin, I.J.3
  • 28
    • 0029909560 scopus 로고    scopus 로고
    • Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells
    • Miller T. M. and Johnson E. M. Jr. (1996) Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells. J. Neurosci. 16, 7487-7495.
    • (1996) J. Neurosci. , vol.16 , pp. 7487-7495
    • Miller, T.M.1    Johnson Jr., E.M.2
  • 30
    • 0029942337 scopus 로고    scopus 로고
    • Histochemical detection of apoptosis in Parkinson's disease
    • Mochizuki H., Goto K., Mori H., and Mizuno Y. (1996) Histochemical detection of apoptosis in Parkinson's disease. J. Neurol. Sci. 137, 120-123.
    • (1996) J. Neurol. Sci. , vol.137 , pp. 120-123
    • Mochizuki, H.1    Goto, K.2    Mori, H.3    Mizuno, Y.4
  • 31
    • 0031051502 scopus 로고    scopus 로고
    • Cloning and expression of a rat brain interleukin-1β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons
    • Ni B., Wu X., Du Y., Su Y., Hamilton-Byrd E., Rockey P. K., Rosteck P., Poirier G. G., and Paul S. M. (1997) Cloning and expression of a rat brain interleukin-1β-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. J. Neurosci. 17, 1561-1569.
    • (1997) J. Neurosci. , vol.17 , pp. 1561-1569
    • Ni, B.1    Wu, X.2    Du, Y.3    Su, Y.4    Hamilton-Byrd, E.5    Rockey, P.K.6    Rosteck, P.7    Poirier, G.G.8    Paul, S.M.9
  • 33
    • 0030020118 scopus 로고    scopus 로고
    • +) and nitric oxide simultaneously causes cyclosporin A-sensitive mitochondrial calcium efflux and depolarisation
    • +) and nitric oxide simultaneously causes cyclosporin A-sensitive mitochondrial calcium efflux and depolarisation. Biochem. Pharmacol. 51, 267-273.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 267-273
    • Packer, M.A.1    Miesel, R.2    Murphy, M.P.3
  • 34
    • 0027373764 scopus 로고
    • Programmed cell death and the control of cell survival: Lessons from the nervous system
    • Raff M. C., Barres B. A., Burne J. F., Coles H. S., Ishizaki Y., and Jacobson M. D. (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262, 695-700.
    • (1993) Science , vol.262 , pp. 695-700
    • Raff, M.C.1    Barres, B.A.2    Burne, J.F.3    Coles, H.S.4    Ishizaki, Y.5    Jacobson, M.D.6
  • 35
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J. B., Weller M., and Klockgether T. (1996) Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16, 4696-4706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 36
    • 0029884711 scopus 로고    scopus 로고
    • Bcl-2 blocks loss of mitochondrial membrane potential while ICE proteases act at a different step during inhibition of death induced by respiratory chain inhibitors
    • Shimizu S., Eguchi Y., Kamiike W., Waguri S., Uchiyama Y., Matsuda H., and Tsujimoto Y. (1996) Bcl-2 blocks loss of mitochondrial membrane potential while ICE proteases act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene 13, 21-29.
    • (1996) Oncogene , vol.13 , pp. 21-29
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 37
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • Susin S. A., Zamzami N., and Castedo M. (1996) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184, 1331-1341.
    • (1996) J. Exp. Med. , vol.184 , pp. 1331-1341
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 38
    • 0010549176 scopus 로고
    • Cerebellar Purkinje cell: Another neuronal basis of MPTP-induced parkinsonism
    • Takada M., Sugimoto T., and Hattori T. (1988) Cerebellar Purkinje cell: another neuronal basis of MPTP-induced parkinsonism. Soc. Neurosci. Abstr. 14, 1026.
    • (1988) Soc. Neurosci. Abstr. , vol.14 , pp. 1026
    • Takada, M.1    Sugimoto, T.2    Hattori, T.3
  • 39
    • 0027180824 scopus 로고
    • Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat
    • Takada M., Sugimoto T., and Hattori T. (1993) Tyrosine hydroxylase immunoreactivity in cerebellar Purkinje cells of the rat. Neurosci. Lett. 150, 61-64.
    • (1993) Neurosci. Lett. , vol.150 , pp. 61-64
    • Takada, M.1    Sugimoto, T.2    Hattori, T.3
  • 40
    • 0030888286 scopus 로고    scopus 로고
    • In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
    • Tatton N. A. and Kish S. J. (1997) In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience 77, 1037-1048.
    • (1997) Neuroscience , vol.77 , pp. 1037-1048
    • Tatton, N.A.1    Kish, S.J.2
  • 41
    • 0027941312 scopus 로고
    • (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis
    • Tatton W. G., Ju W. Y. L., Holland D. P., Tai C., and Kwan M. (1994) (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. J. Neurochem. 63, 1572-1575.
    • (1994) J. Neurochem. , vol.63 , pp. 1572-1575
    • Tatton, W.G.1    Ju, W.Y.L.2    Holland, D.P.3    Tai, C.4    Kwan, M.5
  • 42
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
    • Tipton K. F. and Singer T. P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem. 61, 1191-1206.
    • (1993) J. Neurochem. , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 44
    • 0028133050 scopus 로고
    • Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons
    • Yan G. M., Ni B., Weller M., Wood K. A., and Paul S. M. (1994) Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons. Brain Res. 656, 43-51.
    • (1994) Brain Res. , vol.656 , pp. 43-51
    • Yan, G.M.1    Ni, B.2    Weller, M.3    Wood, K.A.4    Paul, S.M.5
  • 45
  • 46
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J., Shaham S., Ledoux S., Ellis H. M., and Horvitz H. R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75, 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 47
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • Zamzami N., Marchetti P., Castedo M., Zanin C., Vayssiere J. L., Petit P. X., and Kroemer G. (1995) Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181, 1155-1160.
    • (1995) J. Exp. Med. , vol.181 , pp. 1155-1160
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Zanin, C.4    Vayssiere, J.L.5    Petit, P.X.6    Kroemer, G.7
  • 49
    • 0027304263 scopus 로고
    • Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Zang L. Y. and Misra H. P. (1993) Generation of reactive oxygen species during the monoamine oxidase-catalyzed oxidation of the neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Biol. Chem. 268, 16504-16512.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16504-16512
    • Zang, L.Y.1    Misra, H.P.2


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