Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cells

Oncogene

Volumn 24, Issue 23, 2005, Pages 3842-3846

  Hay, Trevor ^a   Patrick, Teresa ^a   Winton, Douglas ^b   Sansom, Owen J ^a   Clarke, Alan R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Apoptosis; Brca2; DNA damage; P53; Small intestine

Indexed keywords

BRCA2 PROTEIN; CYTOCHROME P450 1A1; PROTEIN P53;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; GENE DELETION; INTESTINE FUNCTION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SENSITIZATION; SMALL INTESTINE; STEM CELL; ANIMAL; PATHOLOGY; PHYSIOLOGY;

MURINAE;

ANIMALS; APOPTOSIS; BRCA2 PROTEIN; DNA DAMAGE; INTESTINE, SMALL; MICE; STEM CELLS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 19844365155     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208533     Document Type: Article

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