Akt activation suppresses Chk2-mediated, methylating agent-induced G 2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence

Cancer Research

Volumn 65, Issue 11, 2005, Pages 4861-4869

  Hirose, Yuchi ^a   Katayama, Makoto ^a   Mirzoeva, Olga K ^a   Berger, Mitchel S ^a   Pieper, Russell O ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TEMOZOLOMIDE;

ARTICLE; CELL AGING; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; GLIOBLASTOMA; HUMAN; HUMAN CELL; METHYLATION; MITOSIS; PRIORITY JOURNAL; SENESCENCE; SENSITIZATION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, ALKYLATING; ASTROCYTES; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; DACARBAZINE; ENZYME ACTIVATION; G2 PHASE; GLIOBLASTOMA; HUMANS; METHYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 19644373959     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-2633     Document Type: Article

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