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Volumn 100, Issue 6, 2004, Pages 1060-1065

Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide

Author keywords

Chk1; G2 arrest; p38; Temozolomide

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 7 HYDROXYSTAUROSPORINE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 25C; CHECKPOINT KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

EID: 2442689169     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2004.100.6.1060     Document Type: Article
Times cited : (31)

References (21)
  • 1
    • 0028944359 scopus 로고
    • Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma
    • Bleehen NM, Newlands ES, Lee SM, et al: Cancer Research Campaign phase II trial of temozolomide in metastatic melanoma. J Clin Oncol 13:910-913, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 910-913
    • Bleehen, N.M.1    Newlands, E.S.2    Lee, S.M.3
  • 2
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • Bunz F, Dutriaux A, Lengauer C, et al: Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282:1497-1501, 1998
    • (1998) Science , vol.282 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3
  • 3
    • 0031848832 scopus 로고    scopus 로고
    • Involvement of the mismatch repair system in temozolomide-induced apoptosis
    • D'Atri S, Tentori L, Lacal PM, et al: Involvement of the mismatch repair system in temozolomide-induced apoptosis. Mol Pharmacol 54:334-341, 1998
    • (1998) Mol Pharmacol , vol.54 , pp. 334-341
    • D'Atri, S.1    Tentori, L.2    Lacal, P.M.3
  • 4
    • 0028133013 scopus 로고
    • NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA
    • Denny BJ, Wheelhouse RT, Stevens MFG, et al: NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA. Biochemistry 33:9045-9051, 1994
    • (1994) Biochemistry , vol.33 , pp. 9045-9051
    • Denny, B.J.1    Wheelhouse, R.T.2    Stevens, M.F.G.3
  • 5
    • 0022971473 scopus 로고
    • Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine
    • Goldmacher VS, Cuzick RA Jr, Thilly WG: Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. J Biol Chem 261:12462-12471, 1986
    • (1986) J Biol Chem , vol.261 , pp. 12462-12471
    • Goldmacher, V.S.1    Cuzick Jr., R.A.2    Thilly, W.G.3
  • 6
    • 0026713875 scopus 로고
    • Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15
    • Gu Y, Rosenblatt J, Morgan DO: Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15. EMBO J 11:3995-4005, 1992
    • (1992) EMBO J , vol.11 , pp. 3995-4005
    • Gu, Y.1    Rosenblatt, J.2    Morgan, D.O.3
  • 7
    • 0035422203 scopus 로고    scopus 로고
    • Abrogation of the Chk1-mediated G2 checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells
    • Hirose Y, Berger MS, Pieper RO: Abrogation of the Chk1-mediated G2 checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells. Cancer Res 61:5843-5849, 2001
    • (2001) Cancer Res , vol.61 , pp. 5843-5849
    • Hirose, Y.1    Berger, M.S.2    Pieper, R.O.3
  • 8
    • 0035266245 scopus 로고    scopus 로고
    • p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells
    • Hirose Y, Berger MS, Pieper RO: p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells. Cancer Res 61:1957-1963, 2001
    • (2001) Cancer Res , vol.61 , pp. 1957-1963
    • Hirose, Y.1    Berger, M.S.2    Pieper, R.O.3
  • 9
    • 0242663968 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents
    • Hirose Y, Katayama M, Stokoe D, et al: The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents. Mol Cell Biol 23:8306-8315, 2003
    • (2003) Mol Cell Biol , vol.23 , pp. 8306-8315
    • Hirose, Y.1    Katayama, M.2    Stokoe, D.3
  • 10
    • 0037365825 scopus 로고    scopus 로고
    • 6-methylguanione-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity
    • 6-methylguanione-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity. J Neurosurg 98:591-598, 2003
    • (2003) J Neurosurg , vol.98 , pp. 591-598
    • Hirose, Y.1    Kreklau, E.L.2    Erickson, L.C.3
  • 11
    • 0036841293 scopus 로고    scopus 로고
    • Activation of Akt/protein kinase B overcomes a G2/M cell cycle checkpoint induced by DNA damage
    • Kandel ES, Skeen J, Majewski N, et al: Activation of Akt/protein kinase B overcomes a G2/M cell cycle checkpoint induced by DNA damage. Mol Cell Biol 22:7831-7841, 2002
    • (2002) Mol Cell Biol , vol.22 , pp. 7831-7841
    • Kandel, E.S.1    Skeen, J.2    Majewski, N.3
  • 12
    • 0026750738 scopus 로고
    • Self-destruction and tolerance in resistance of mammalian cells to alkylation damage
    • Karran, P, Bignami M: Self-destruction and tolerance in resistance of mammalian cells to alkylation damage. Nucleic Acids Res 20:2933-2940, 1992
    • (1992) Nucleic Acids Res , vol.20 , pp. 2933-2940
    • Karran, P.1    Bignami, M.2
  • 13
    • 0020332947 scopus 로고
    • 6-methylguanine residues in E. Coli DNA
    • 6-methylguanine residues in E. Coli DNA. Nature 296:868-869, 1982
    • (1982) Nature , vol.296 , pp. 868-869
    • Karran, P.1    Marinus, M.G.2
  • 14
    • 0027292234 scopus 로고
    • An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
    • Kat A, Thilly WG, Fang WH, et al: An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci 90:6424-6428, 1993
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 6424-6428
    • Kat, A.1    Thilly, W.G.2    Fang, W.H.3
  • 15
    • 0033629383 scopus 로고    scopus 로고
    • Cell cycle regulation by the cdc25 phosphatase family
    • Nilsson I, Hoffman I: Cell cycle regulation by the cdc25 phosphatase family. Prog Cell Cycle Res 4:107-114, 2000
    • (2000) Prog Cell Cycle Res , vol.4 , pp. 107-114
    • Nilsson, I.1    Hoffman, I.2
  • 16
    • 0030611095 scopus 로고    scopus 로고
    • 2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
    • 2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277:1501-1505, 1997
    • (1997) Science , vol.277 , pp. 1501-1505
    • Peng, C.Y.1    Graves, P.R.2    Thoma, R.S.3
  • 17
    • 0034120215 scopus 로고    scopus 로고
    • Future directions in the treatment of malignant gliomas with temozolomide
    • Prados MD: Future directions in the treatment of malignant gliomas with temozolomide. Semin Oncol (Suppl 6) 27:41-46, 2000
    • (2000) Semin Oncol (Suppl 6) , vol.27 , pp. 41-46
    • Prados, M.D.1
  • 18
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through cdc25
    • Sanchez Y, Wong C, Thoma RS, et al: Conservation of the chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through cdc25. Science 277:1497-1501, 1997
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thoma, R.S.3
  • 19
    • 0037238696 scopus 로고    scopus 로고
    • Cyclin-dependent kinase modulators studied at the NCI: Pre-clinical and clinical studies
    • Sausville EA: Cyclin-dependent kinase modulators studied at the NCI: pre-clinical and clinical studies. Curr Med Chem Anti-Canc Agents 3:47-56, 2003
    • (2003) Curr Med Chem Anti-Canc Agents , vol.3 , pp. 47-56
    • Sausville, E.A.1
  • 20
    • 1342335029 scopus 로고    scopus 로고
    • Novel small molecule cyclin-dependent kinases modulators in human clinical trials
    • Senderowicz AM: Novel small molecule cyclin-dependent kinases modulators in human clinical trials. Cancer Biol Ther (Suppl 1) 2:S84-S95, 2003
    • (2003) Cancer Biol Ther (Suppl 1) , vol.2
    • Senderowicz, A.M.1
  • 21
    • 0037018847 scopus 로고    scopus 로고
    • A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
    • Shtivelman E, Sussman J, Stokoe D: A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle. Curr Biol 12:919-924, 2002
    • (2002) Curr Biol , vol.12 , pp. 919-924
    • Shtivelman, E.1    Sussman, J.2    Stokoe, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.